nicotinate ribose (BioDeep_00000397441)

Main id: BioDeep_00000004318

 

PANOMIX_OTCML-2023


代谢物信息卡片


1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate

化学式: C11H13NO6 (255.0743)
中文名称: 烟酸核糖
谱图信息: 最多检出来源 not specific(blood) 37.5%

分子结构信息

SMILES: C1=CC(=C[N+](=C1)C2C(C(C(O2)CO)O)O)C(=O)[O-]
InChI: InChI=1S/C11H13NO6/c13-5-7-8(14)9(15)10(18-7)12-3-1-2-6(4-12)11(16)17/h1-4,7-10,13-15H,5H2/t7-,8-,9-,10-/m1/s1

描述信息

D-ribosylnicotinate is conjugate base of D-ribosylnicotinic acid. It has a role as a human metabolite. It is a conjugate base of a D-ribosylnicotinic acid.
Nicotinic acid riboside is a natural product found in Vitis vinifera, Saccharomyces cerevisiae, and Homo sapiens with data available.
Conjugate base of D-ribosylnicotinic acid.
Nicotinic acid riboside is a NAD+ precursor in human cells. Nicotinic acid riboside is an authentic intermediate of human NAD+ metabolism[1][2].

同义名列表

14 个代谢物同义名

1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1|E?-pyridin-1-ylium-3-carboxylate; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyridin-1-ium-3-carboxylate; Pyridinium, 3-carboxy-1-beta-D-ribofuranosyl-, inner salt; 1-(beta-D-ribofuranosyl)pyridinium-3-carboxylate; nicotinic acid ribonucleoside; nicotinate ribonucleoside; beta-D-Ribosylnicotinate; Nicotinic acid riboside; nicotinic acid ribose; nicotinate riboside; D-ribosylnicotinate; nicotinate ribose; ribosylnicotinate



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(4)

BioCyc(0)

PlantCyc(0)

代谢反应

44 个相关的代谢反应过程信息。

Reactome(44)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Brian J Koos, Jeffrey A Gornbein. Early pregnancy metabolites predict gestational diabetes mellitus: implications for fetal programming. American journal of obstetrics and gynecology. 2021 02; 224(2):215.e1-215.e7. doi: 10.1016/j.ajog.2020.07.050. [PMID: 32739399]
  • Hiroshi Ashihara, Wei-Wei Deng. Pyridine metabolism in tea plants: salvage, conjugate formation and catabolism. Journal of plant research. 2012 Nov; 125(6):781-91. doi: 10.1007/s10265-012-0490-x. [PMID: 22527843]
  • Ayu Matsui, Hiroshi Ashihara. Nicotinate riboside salvage in plants: presence of nicotinate riboside kinase in mungbean seedlings. Plant physiology and biochemistry : PPB. 2008 Jan; 46(1):104-8. doi: 10.1016/j.plaphy.2007.10.008. [PMID: 18042392]
  • R J Knox, F Friedlos, M Jarman, L C Davies, P Goddard, G M Anlezark, R G Melton, R F Sherwood. Virtual cofactors for an Escherichia coli nitroreductase enzyme: relevance to reductively activated prodrugs in antibody directed enzyme prodrug therapy (ADEPT). Biochemical pharmacology. 1995 May; 49(11):1641-7. doi: 10.1016/0006-2952(95)00077-d. [PMID: 7786305]
  • F Friedlos, P J Biggs, J A Abrahamson, R J Knox. Potentiation of CB 1954 cytotoxicity by reduced pyridine nucleotides in human tumour cells by stimulation of DT diaphorase activity. Biochemical pharmacology. 1992 Nov; 44(9):1739-43. doi: 10.1016/0006-2952(92)90067-s. [PMID: 1449531]