Tetramethylluteolin (BioDeep_00000396878)

 

Secondary id: BioDeep_00000226803, BioDeep_00000270490, BioDeep_00000866170

PANOMIX_OTCML-2023


代谢物信息卡片


3 inverted exclamation mark ,4 inverted exclamation mark ,5,7-Tetramethoxyflavone

化学式: C19H18O6 (342.11033280000004)
中文名称: 3,4,5,7-四甲氧基黄酮, 木犀草素四甲醚, 3,4,5,7-四甲氧基黄酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1(OC)=CC2OC(C3C=C(OC)C(OC)=CC=3)=CC(=O)C=2C(OC)=C1
InChI: InChI=1S/C19H18O6/c1-21-12-8-17(24-4)19-13(20)10-15(25-18(19)9-12)11-5-6-14(22-2)16(7-11)23-3/h5-10H,1-4H3

描述信息

3,4,5,7-Tetramethoxyflavone is a natural product found in Orthosiphon aristatus, Bryobium eriaeoides, and other organisms with data available.
5,7,3',4'-Tetramethoxyflavone, one of the major polymethoxyflavones (PMFs) isolated from M. exotica, possesses various bioactivities, including anti-fungal, anti-malarial, anti-mycobacterial, and anti-inflammatory activities. 5,7,3',4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling[1].
5,7,3',4'-Tetramethoxyflavone, one of the major polymethoxyflavones (PMFs) isolated from M. exotica, possesses various bioactivities, including anti-fungal, anti-malarial, anti-mycobacterial, and anti-inflammatory activities. 5,7,3',4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling[1].

同义名列表

18 个代谢物同义名

3 inverted exclamation mark ,4 inverted exclamation mark ,5,7-Tetramethoxyflavone; 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-; 2-(3,4-Dimethoxyphenyl)-5,7-dimethoxy-4H-1-benzopyran-4-one; 2-(3,4-Dimethoxyphenyl)-5,7-dimethoxy-4H-chromen-4-one #; 2-(3,4-Dimethoxyphenyl)-5,7-dimethoxy-4H-chromen-4-one; 2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-chromen-4-one; 2-(3,4-dimethoxyphenyl)-5,7-dimethoxychromen-4-one; Luteolin 5,7,3,4-tetramethyl ether; Flavone, 3,4,5,7-tetramethoxy; ?3,4,5,7-TETRAMETHOXYFLAVONE; 3,4,5,7-tetramethyl-luteolin; 3,4,5,7-Tetramethoxyflavone; 5,7,3,4-Tetramethoxyflavone; 5,7,3,4-tetramethylluteolin; Luteolin tetramethyl ether; Tetramethoxyluteolin; Tetramethylluteolin; 5,7,3',4'-Tetramethoxyflavone



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Noriyuki Natsume, Aki Yamano, Akio Watanabe, Takayuki Yonezawa, Je-Tae Woo, Tohru Yamakuni, Toshiaki Teruya. Effect of methoxyflavones contained in Kaempferia parviflora on CRE-mediated transcription in PC12D cells. Bioorganic & medicinal chemistry letters. 2020 12; 30(23):127606. doi: 10.1016/j.bmcl.2020.127606. [PMID: 33038547]
  • Wen-Chien Lu, Jenn-Feng Sheen, Lucy Sun Hwang, Guor-Jien Wei. Identification of 5,7,3',4'-tetramethoxyflavone metabolites in rat urine by the isotope-labeling method and ultrahigh-performance liquid chromatography-electrospray ionization-mass spectrometry. Journal of agricultural and food chemistry. 2012 Aug; 60(33):8123-8. doi: 10.1021/jf302043a. [PMID: 22812915]
  • Kikuyo Nakao, Kazuya Murata, Takahiro Deguchi, Kimihisa Itoh, Takanori Fujita, Masayuki Higashino, Yuri Yoshioka, Shin-Ichi Matsumura, Rika Tanaka, Tetsuro Shinada, Yasufumi Ohfune, Hideaki Matsuda. Xanthine oxidase inhibitory activities and crystal structures of methoxyflavones from Kaempferia parviflora rhizome. Biological & pharmaceutical bulletin. 2011; 34(7):1143-6. doi: 10.1248/bpb.34.1143. [PMID: 21720029]
  • Chavi Yenjai, Khanchara Prasanphen, Supawadee Daodee, Varima Wongpanich, Prasat Kittakoop. Bioactive flavonoids from Kaempferia parviflora. Fitoterapia. 2004 Jan; 75(1):89-92. doi: 10.1016/j.fitote.2003.08.017. [PMID: 14693228]
  • I M Lyckander, K E Malterud. Lipophilic flavonoids from Orthosiphon spicatus prevent oxidative inactivation of 15-lipoxygenase. Prostaglandins, leukotrienes, and essential fatty acids. 1996 Apr; 54(4):239-46. doi: 10.1016/s0952-3278(96)90054-x. [PMID: 8804120]