Artonin E (BioDeep_00000269958)

Main id: BioDeep_00000026625

 

PANOMIX_OTCML-2023


代谢物信息卡片


5-Hydroxy-8,8-dimethyl-3- (3-methyl-2-butenyl) -2- (2,4,5-trihydroxyphenyl) -4H,8H-benzo [ 1,2-b:3,4-b ] dipyran-4-one

化学式: C25H24O7 (436.1521954)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c12cc(c3c(c1C=CC(O2)(C)C)oc(c(c3=O)CC=C(C)C)c1cc(c(cc1O)O)O)O
InChI: InChI=1S/C25H24O7/c1-12(2)5-6-14-22(30)21-19(29)11-20-13(7-8-25(3,4)32-20)24(21)31-23(14)15-9-17(27)18(28)10-16(15)26/h5,7-11,26-29H,6H2,1-4H3

描述信息

同义名列表

12 个代谢物同义名

4H,8H-Benzo(1,2-b:3,4-b)dipyran-4-one, 5-hydroxy-8,8-dimethyl-3-(3-methyl-2-butenyl)-2-(2,4,5-trihydroxyphenyl)-; 5-Hydroxy-8,8-dimethyl-3-(3-methyl-but-2-enyl)-2-(2,4,5-trihydroxy-phenyl)-8H-benzo[1,2-b:4,3-b]dipyran-4-one; 5-hydroxy-8,8-dimethyl-3-(3-methylbut-2-enyl)-2-(2,4,5-trihydroxyphenyl)-4-pyrano[6,5-h]chromenone; 5-hydroxy-8,8-dimethyl-3-(3-methylbut-2-enyl)-2-(2,4,5-trihydroxyphenyl)pyrano[6,5-h]chromen-4-one; 5-Hydroxymorusin; AIDS-095972; 129683-93-8; AIDS095972; Artonin E; 5-Hydroxy-8,8-dimethyl-3- (3-methyl-2-butenyl) -2- (2,4,5-trihydroxyphenyl) -4H,8H-benzo [ 1,2-b:3,4-b ] dipyran-4-one; 5-Hydroxy-8,8-dimethyl-3-(3-methyl-2-butenyl)-2-(2,4,5-trihydroxyphenyl)-4H,8H-benzo[1,2-b:3,4-b]dipyran-4-one; KB 3



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yulin Ren, Esperanza J Carcache de Blanco, James R Fuchs, Djaja D Soejarto, Joanna E Burdette, Steven M Swanson, A Douglas Kinghorn. Potential Anticancer Agents Characterized from Selected Tropical Plants. Journal of natural products. 2019 03; 82(3):657-679. doi: 10.1021/acs.jnatprod.9b00018. [PMID: 30830783]
  • Imaobong Christopher Etti, Rasedee Abdullah, Arifah Kadir, Najihah Mohd Hashim, Swee Keong Yeap, Mustapha Umar Imam, Faiqah Ramli, Ibrahim Malami, Kian Lim Lam, Ubong Etti, Peter Waziri, Marsitoh Rahman. The molecular mechanism of the anticancer effect of Artonin E in MDA-MB 231 triple negative breast cancer cells. PloS one. 2017; 12(8):e0182357. doi: 10.1371/journal.pone.0182357. [PMID: 28771532]
  • Ekkarat Wongpankam, Preedakorn Chunhacha, Varisa Pongrakhananon, Boonchoo Sritularak, Pithi Chanvorachote. Artonin E mediates MCL1 down-regulation and sensitizes lung cancer cells to anoikis. Anticancer research. 2012 Dec; 32(12):5343-51. doi: NULL. [PMID: 23225436]
  • Victor Kuete, Patrick Y Ango, Ghislain W Fotso, Gilbert D W F Kapche, Jean P Dzoyem, Arlette G Wouking, Bonaventure T Ngadjui, Berhanu M Abegaz. Antimicrobial activities of the methanol extract and compounds from Artocarpus communis (Moraceae). BMC complementary and alternative medicine. 2011 May; 11(?):42. doi: 10.1186/1472-6882-11-42. [PMID: 21612612]
  • U L B Jayasinghe, T B Samarakoon, B M M Kumarihamy, N Hara, Y Fujimoto. Four new prenylated flavonoids and xanthones from the root bark of Artocarpus nobilis. Fitoterapia. 2008 Jan; 79(1):37-41. doi: 10.1016/j.fitote.2007.07.014. [PMID: 17855020]
  • Yong-Hong Wang, Ai-Jun Hou, Lei Chen, Dao-Feng Chen, Han-Dong Sun, Qin-Shi Zhao, Kenneth F Bastow, Yuka Nakanish, Xi-Hong Wang, Kuo-Hsiung Lee. New isoprenylated flavones, artochamins A--E, and cytotoxic principles from Artocarpus chama. Journal of natural products. 2004 May; 67(5):757-61. doi: 10.1021/np030467y. [PMID: 15165133]
  • Shugeng Cao, Mark S Butler, Antony D Buss. Flavonoids from Artocarpus lanceifolius. Natural product research. 2003 Apr; 17(2):79-81. doi: 10.1080/1478641031000103641. [PMID: 12713118]
  • Eun-Kyoung Seo, Dongho Lee, Young Geun Shin, Hee-Byung Chai, Hernán A Navarro, Leonardus B S Kardono, Ismail Rahman, Geoffrey A Cordell, Norman R Farnsworth, John M Pezzuto, A Douglas Kinghorn, Mansukh C Wani, Monroe E Wall. Bioactive prenylated flavonoids from the stem bark of Artocarpus kemando. Archives of pharmacal research. 2003 Feb; 26(2):124-7. doi: 10.1007/bf02976656. [PMID: 12643587]