Corydine (BioDeep_00000229998)

PANOMIX_OTCML-2023

代谢物信息卡片

4H-DIBENZO(DE,G)QUINOLIN-1-OL, 5,6,6A,7-TETRAHYDRO-2,10,11-TRIMETHOXY-6-METHYL-, (6AS)-

化学式: C20H23NO4 (341.16269980000004)
中文名称: 紫菫定酚, 紫堇定
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CN1CCC2=CC(=C(C3=C2C1CC4=C3C(=C(C=C4)OC)OC)O)OC
InChI: InChI=1S/C20H23NO4/c1-21-8-7-12-10-15(24-3)19(22)18-16(12)13(21)9-11-5-6-14(23-2)20(25-4)17(11)18/h5-6,10,13,22H,7-9H2,1-4H3/t13-/m0/s1

描述信息

Corydine is a natural product found in Zanthoxylum oxyphyllum, Aconitum orientale, and other organisms with data available.

同义名列表

26 个代谢物同义名

4H-Dibenzo(de,g)quinolin-1-ol, 5,6,6a,7-tetrahydro-2,10,11-trimethoxy-6-methyl-, (S)-; 5-21-06-00134 (Beilstein Handbook Reference); 6a-alpha-APORPHIN-1-OL, 2,10,11-TRIMETHOXY-; O(sup 11)-Methylcorytuberine; (S)-(+)-Corydine; STOCK1N-48890; Glaucentrine; Glaucentrin; BRN 0095568; d-Corydine; Corydine; 4H-DIBENZO(DE,G)QUINOLIN-1-OL, 5,6,6A,7-TETRAHYDRO-2,10,11-TRIMETHOXY-6-METHYL-, (6AS)-; (6AS)-5,6,6A,7-TETRAHYDRO-2,10,11-TRIMETHOXY-6-METHYL-4H-DIBENZO(DE,G)QUINOLIN-1-OL; (6aS)-2,10,11-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1-ol; (S)-2,10,11-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1-ol; 2,10,11-Trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1-ol; CORYTUBERINE METHYL ETHER [MI]; Corytuberine methyl ether; O11-Methylcorytuberine; corydine hydrochloride; corydine, (R)-isomer; UNII-1O1D15OP5R; CORYDINE [MI]; (+)-Corydine; (S)-Corydine; 1O1D15OP5R

数据库引用编号

7 个数据库交叉引用编号

PubChem: 10153
ChEMBL: CHEMBL489524
MeSH: corydine
ChemIDplus: 0000476697
chemspider: 9747
CAS: 476-69-7
medchemexpress: HY-N2571

分类词条

异喹啉生物碱

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

45 个相关的物种来源信息

632164 - Aconitum leucostomum: 10.1007/BF00581601
112592 - Aconitum orientale: 10.1007/BF00597733
301862 - Annona reticulata: 10.1007/978-3-642-22144-6_19
301693 - Annona squamosa: 10.1016/0031-9422(72)85042-8
1433301 - Berberis actinacantha: 10.1039/C39830000799
559508 - Berberis repens: 10.1021/NP50018A011
71251 - Chelidonium majus: 10.1055/S-2006-957498
2662156 - Cissampelos fasciculata: 10.1016/S0040-4020(01)90186-3
984853 - Consolida hellespontica: 10.3987/COM-92-6277
581246 - Corydalis cava: 10.1055/S-2007-969652
38904 - Corydalis decumbens: 10.3987/COM-93-6445
765397 - Croton hemiargyreus: 10.1002/(SICI)1099-1565(199909/10)10:5<254::AID-PCA462>3.0.CO;2-Q
128651 - Damburneya salicifolia: 10.1021/NP960195H
610223 - Dehaasia hainanensis: 10.1177/1934578X0700200115
54418 - Dicentra peregrina: 10.1201/B16160-69
1533087 - Glaucium corniculatum:
1353837 - Glaucium fimbrilligerum:
56853 - Glaucium flavum:
1353838 - Glaucium squamigerum:
343270 - Guatteria amplifolia: 10.1016/J.BSE.2011.03.001
74947 - Hedycarya angustifolia: 10.3987/R-1987-02-0447
72180 - Hypecoum leptocarpum: 10.1135/CCCC19870508
391933 - Hypecoum procumbens: 10.1135/CCCC19870508
54415 - Lamprocapnos spectabilis:
74887 - Laurelia novae-zelandiae: 10.1021/NP50033A032
1609886 - Neolitsea konishii: 10.1002/JCCS.199800018
881612 - Ocotea velloziana: 10.1016/0031-9422(94)00961-R
357464 - Papaver argemone: 10.1135/CCCC19881845
215227 - Papaver bracteatum: 10.1135/CCCC19851216
357469 - Papaver dubium: 10.1080/10575630008041232
357470 - Papaver glaucum: 10.1135/CCCC19862232
357473 - Papaver pavoninum: 10.1135/CCCC19881845
152836 - Papaver tatricum: 10.1135/CCCC19851745
54436 - Pseudofumaria lutea: 10.1016/0031-9422(93)85313-G
1184746 - Stephania abyssinica: 10.1016/S0031-9422(00)80650-0
152367 - Stephania cephalantha:
1501467 - Stephania lincangensis: 10.1016/S0031-9422(00)80650-0
1924984 - Stephania pierrei: 10.1021/NP50099A005
425106 - Stephania tetrandra: 10.1021/NP50084A023
56864 - Stylophorum diphyllum: 10.1135/CCCC19840704
46970 - Thalictrum dioicum: 10.1016/S0040-4020(01)82640-5
1264574 - Thalictrum tuberiferum: 10.1016/0040-4039(64)83163-4
1056476 - Zanthoxylum oxyphyllum: 10.1016/S0031-9422(00)94287-0
33090 - 延胡索: -
33090 - 紫堇: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Teresa Kaserer, Theresa Steinacher, Roman Kainhofer, Filippo Erli, Sonja Sturm, Birgit Waltenberger, Daniela Schuster, Mariana Spetea. Identification and characterization of plant-derived alkaloids, corydine and corydaline, as novel mu opioid receptor agonists. Scientific reports. 2020 08; 10(1):13804. doi: 10.1038/s41598-020-70493-1. [PMID: 32796875]
Qian Yan, Ruxia Li, Aiyi Xin, Yin Han, Yanxia Zhang, Junxi Liu, Wenguang Li, Duolong Di. Design, synthesis, and anticancer properties of isocorydine derivatives. Bioorganic & medicinal chemistry. 2017 12; 25(24):6542-6553. doi: 10.1016/j.bmc.2017.10.027. [PMID: 29103873]
Anne Adsersen, Anne Kjølbye, Ole Dall, Anna K Jäger. Acetylcholinesterase and butyrylcholinesterase inhibitory compounds from Corydalis cava Schweigg. & Kort. Journal of ethnopharmacology. 2007 Aug; 113(1):179-82. doi: 10.1016/j.jep.2007.05.006. [PMID: 17574358]