(6S)-2-Amino-6-[(1S,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-3H-pteridin-4-one (BioDeep_00000183524)

Main id: BioDeep_00000001257

 

human metabolite PANOMIX_OTCML-2023 blood metabolite


代谢物信息卡片


2-amino-6-(1,2-Dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-5,6,7,8-tetrahydro-2-amino-6-(1,2-dihydroxypropyl)-4(1H)-pteridinone

化学式: C9H15N5O3 (241.1175)
中文名称: 四氢生物喋呤
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
InChI: InChI=1S/C9H15N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17)

描述信息

Tetrahydrobiopterin or BH4 is a cofactor in the synthesis of nitric oxide. It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5-hydroxytryptophan via tryptophan hydroxylase. A defect in BH4 production and/or a defect in the enzyme dihydropteridine reductase (DHPR) causes phenylketonuria type IV, as well as dopa-responsive dystonias. -- Wikipedia. [HMDB]
Tetrahydrobiopterin ((Rac)-Sapropterin) is a cofactor of the aromatic amino acid hydroxylases enzymes and also acts as an essential cofactor for all nitric oxide synthase (NOS) isoforms.

同义名列表

34 个代谢物同义名

2-amino-6-(1,2-Dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-5,6,7,8-tetrahydro-2-amino-6-(1,2-dihydroxypropyl)-4(1H)-pteridinone; (6S)-2-Amino-6-[(1S,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-3H-pteridin-4-one; L-erythro-2-amino-6-(1,2-Dihydroxypropyl)-5,6,7,8-tetrahydro-4(3H)-pteridinon; (1R,2S)-(2-amino-3,4,5,6,7,8-hexahydro-4-oxo-6-Pteridinyl)-1,2-propandiol; 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-pteridinone; 5,6,7,8-tetrahydro-2-amino-6-(1,2-Dihydroxypropyl)-4(1H)-pteridinone; 2-amino-6-(1,2-Dihydroxypropyl)-5,6,7,8-tetrahydro-4(1H)-pteridinone; 2-amino-6-(1,2-dihydroxypropyl)-1,4,5,6,7,8-hexahydropteridin-4-one; 5,6,7,8-Tetrahydrobiopterin, (S-(r*,s*))-isomer; 6R-L-erythro-5,6,7,8-Tetrahydrobiopterin; 1-Butanone, 1-(2,4,5-trihydroxyphenyl); 5,6,7,8-tetrahydro-L-Erythrobiopterin; 5,6,7,8-erythro-Tetrahydrobiopterin; Phenylalanine hydroxylase cofactor; 5,6,7,8-Tetrahydrodictyopterin; 2,4,5-Trihydroxybutyrophenone; 2,4,5-trihydroxybutyrophenone; 5,6,7,8-Tetrahydrobiopterin; Sapropterin dihydrochloride; D-threo-Tetrahydrobiopterin; 5,6,7,8-Tetra-H-biopterin; Trihydroxybutyrophenone; tetrahydro-6-Biopterin; Tetra-hydro-biopterin; tetrahydrobiopterin; Tetra-H-biopterin; Sapropterin; 6R-BH4; Kuvan; THBP; BPH4; BH4; (Rac)-Sapropterin; Tetrahydrobiopterin



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代谢反应

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1 个相关的物种来源信息

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