Morelloflavone (BioDeep_00000181086)

Main id: BioDeep_00000238582

 

human metabolite PANOMIX_OTCML-2023 blood metabolite natural product


代谢物信息卡片


8-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-1-benzopyran-3-yl]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one

化学式: C30H20O11 (556.100557)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC=C1C2C(C(=O)C3=C(C=C(C=C3O2)O)O)C4=C(C=C(C5=C4OC(=CC5=O)C6=CC(=C(C=C6)O)O)O)O)O
InChI: InChI=1S/C30H20O11/c31-14-4-1-12(2-5-14)29-27(28(39)25-18(35)8-15(32)9-23(25)41-29)26-20(37)10-19(36)24-21(38)11-22(40-30(24)26)13-3-6-16(33)17(34)7-13/h1-11,27,29,31-37H

描述信息

同义名列表

3 个代谢物同义名

8-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-1-benzopyran-3-yl]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one; 8-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-2,3-dihydro-1-benzopyran-3-yl]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one; Morelloflavone



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

73 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Luis Carrillo-Hormaza, Ana M Ramírez, Edison Osorio. Chemometric classification of Garcinia madruno raw material: Impact of the regional origin and ripeness stage of a neotropical exotic species. Food chemistry. 2019 Sep; 293(?):291-298. doi: 10.1016/j.foodchem.2019.04.118. [PMID: 31151614]
  • Blaise Kemajou Nganou, Ingrid Simo Konga, Aimé G Fankam, Gabin Thierry M Bitchagno, Gaielle Sonfack, Paul Nayim, Ilhami Celik, Sema Koyutürk, Victor Kuete, Pierre Tane. Guttiferone BL with antibacterial activity from the fruits of Allanblackia gabonensis. Natural product research. 2019 Sep; 33(18):2638-2646. doi: 10.1080/14786419.2018.1465424. [PMID: 29683342]
  • Tomisin Happy Ogunwa, Kenichi Taii, Kei Sadakane, Yuka Kawata, Shinsaku Maruta, Takayuki Miyanishi. Morelloflavone as a novel inhibitor of mitotic kinesin Eg5. Journal of biochemistry. 2019 Aug; 166(2):129-137. doi: 10.1093/jb/mvz015. [PMID: 30785183]
  • Yulin Ren, Esperanza J Carcache de Blanco, James R Fuchs, Djaja D Soejarto, Joanna E Burdette, Steven M Swanson, A Douglas Kinghorn. Potential Anticancer Agents Characterized from Selected Tropical Plants. Journal of natural products. 2019 03; 82(3):657-679. doi: 10.1021/acs.jnatprod.9b00018. [PMID: 30830783]
  • G Brusotti, A Papetti, M Serra, C Temporini, E Marini, S Orlandini, A Kada Sanda, P Watcho, P Kamtchouing. Allanblackia floribunda Oliv.: An aphrodisiac plant with vasorelaxant properties. Journal of ethnopharmacology. 2016 Nov; 192(?):480-485. doi: 10.1016/j.jep.2016.09.033. [PMID: 27647010]
  • A P Anu Aravind, K R T Asha, K B Rameshkumar. Phytochemical analysis and antioxidant potential of the leaves of Garcinia travancorica Bedd. Natural product research. 2016; 30(2):232-6. doi: 10.1080/14786419.2015.1043551. [PMID: 25982126]
  • Yunfang Li, Jia Xu, Yu Chen, Zhinan Mei, Yuxiu Xiao. Screening of inhibitors of glycogen synthase kinase-3β from traditional Chinese medicines using enzyme-immobilized magnetic beads combined with high-performance liquid chromatography. Journal of chromatography. A. 2015 Dec; 1425(?):8-16. doi: 10.1016/j.chroma.2015.10.062. [PMID: 26610618]
  • Anatole Guy Blaise Azebaze, Jean Emmanuel Mbosso Teinkela, Edwige Laure Nguemfo, Alexis Valentin, Alain Bertrand Dongmo, Juliette Catherine Vardamides. Antiplasmodial activity of some phenolic compounds from Cameroonians Allanblackia. African health sciences. 2015 Sep; 15(3):835-40. doi: 10.4314/ahs.v15i3.18. [PMID: 26957972]
  • Aline Pereira Castro, Ana Carolina Alves de Mattos, Neusa Araújo Pereira, Naira Ferreira Anchieta, Matheus Siqueira Silva, Danielle Ferreira Dias, Claudinei Alves Silva, Giulliano Vilela Barros, Raquel Lopes Martins Souza, Marcelo Henrique Dos Santos, Marcos José Marques. Potent Schistosomicidal Constituents from Garcinia brasiliensis. Planta medica. 2015 Jun; 81(9):733-41. doi: 10.1055/s-0035-1545927. [PMID: 25905590]
  • Decha Pinkaew, Nongporn Hutadilok-Towatana, Ba-Bie Teng, Wilawan Mahabusarakam, Ken Fujise. Morelloflavone, a biflavonoid inhibitor of migration-related kinases, ameliorates atherosclerosis in mice. American journal of physiology. Heart and circulatory physiology. 2012 Jan; 302(2):H451-8. doi: 10.1152/ajpheart.00669.2011. [PMID: 22058152]
  • Decha Pinkaew, Sung Gook Cho, David Y Hui, John E Wiktorowicz, Nongporn Hutadilok-Towatana, Wilawan Mahabusarakam, Moltira Tonganunt, Lewis J Stafford, Amornrat Phongdara, Mingyao Liu, Ken Fujise. Morelloflavone blocks injury-induced neointimal formation by inhibiting vascular smooth muscle cell migration. Biochimica et biophysica acta. 2009 Jan; 1790(1):31-9. doi: 10.1016/j.bbagen.2008.09.006. [PMID: 18930785]
  • Shuai Li, Ruo-Yun Chen, De-Quan Yu. [Study on chemical constituents of Myricaria paniculata I]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2007 Mar; 32(5):403-6. doi: ". [PMID: 17511145]