Fluorescein dilaurate (BioDeep_00000179124)
human metabolite blood metabolite
代谢物信息卡片
3-(Dodecanoyloxy)-3-oxo-3H-spiro[2-benzofuran-1,9-xanthene]-6-yl dodecanoic acid
化学式: C44H56O7 (696.4026)
中文名称: 荧光素二月桂酯
谱图信息:
最多检出来源 Homo sapiens(blood) 42.86%
分子结构信息
SMILES: CCCCCCCCCCCC(=O)OC1=CC2=C(C=C1)C1(OC(=O)C3=CC=CC=C13)C1=C(O2)C=C(OC(=O)CCCCCCCCCCC)C=C1
InChI: InChI=1S/C44H56O7/c1-3-5-7-9-11-13-15-17-19-25-41(45)48-33-27-29-37-39(31-33)50-40-32-34(49-42(46)26-20-18-16-14-12-10-8-6-4-2)28-30-38(40)44(37)36-24-22-21-23-35(36)43(47)51-44/h21-24,27-32H,3-20,25-26H2,1-2H3
描述信息
D004396 - Coloring Agents > D005456 - Fluorescent Dyes > D005452 - Fluoresceins
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents
同义名列表
9 个代谢物同义名
3-(Dodecanoyloxy)-3-oxo-3H-spiro[2-benzofuran-1,9-xanthene]-6-yl dodecanoic acid; 3-(dodecanoyloxy)-3-oxo-3H-spiro[2-benzofuran-1,9-xanthene]-6-yl dodecanoate; (6-dodecanoyloxy-3-oxospiro[2-benzofuran-1,9-xanthene]-3-yl) dodecanoate; 3-(dodecanoyloxy)-3-oxospiro[2-benzofuran-1,9-xanthene]-6-yl dodecanoate; Fluorescein dilauric acid; Fluorescein dilaurate; Pancreolauryl test; Pancreolauryl; 3'-(Dodecanoyloxy)-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-6'-yl dodecanoic acid
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Maria Beatriz Di Carlo, Fabiana N López Mingorance, M del Carmen Maselli, Susana Hamamura, Graciela Otero, Osvaldo M Tiscornia, Gustavo A Negri. [Biochemical profile of the pancreatic function: pancreolauril and oral glucose tolerance tests].
Acta gastroenterologica Latinoamericana.
2010 Jun; 40(2):128-33. doi:
NULL. [PMID: 20645560] - D A Elphick, K Kapur. Comparing the urinary pancreolauryl ratio and faecal elastase-1 as indicators of pancreatic insufficiency in clinical practice.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].
2005; 5(2-3):196-200. doi:
10.1159/000085271. [PMID: 15849489] - R S Chowdhury, C E Forsmark. Review article: Pancreatic function testing.
Alimentary pharmacology & therapeutics.
2003 Mar; 17(6):733-50. doi:
10.1046/j.1365-2036.2003.01495.x. [PMID: 12641496] - A Leodolter, S Kahl, J E Domínguez-Muñoz, C Gerards, B Glasbrenner, P Malfertheiner. Comparison of two tubeless function tests in the assessment of mild-to-moderate exocrine pancreatic insufficiency.
European journal of gastroenterology & hepatology.
2000 Dec; 12(12):1335-8. doi:
10.1097/00042737-200012120-00012. [PMID: 11192324] - C von Tirpitz, B Glasbrenner, D Mayer, P Malfertheiner, G Adler. Comparison of different endocrine stimulation tests in nondiabetic patients with chronic pancreatitis.
Hepato-gastroenterology.
1998 Jul; 45(22):1111-6. doi:
NULL. [PMID: 9756016] - J E Domínguez-Muñoz, P Malfertheiner. Optimized serum pancreolauryl test for differentiating patients with and without chronic pancreatitis.
Clinical chemistry.
1998 Apr; 44(4):869-75. doi:
10.1093/clinchem/44.4.869. [PMID: 9580240] - G Lock, R Kadow, H Messmann, H Zirngibl, J Schölmerich, A Holstege. Modified serum pancreolauryl test in chronic pancreatitis: evaluation in comparison to endoscopic retrograde pancreatography.
Hepato-gastroenterology.
1997 Jul; 44(16):1110-6. doi:
NULL. [PMID: 9261608] - P Zhao, J Tu, J J van den Oord, J Fevery. Damage to duct epithelium is necessary to develop progressing lesions of chronic pancreatitis in the cat.
Hepato-gastroenterology.
1996 Nov; 43(12):1620-6. doi:
NULL. [PMID: 8975976] - H Friess, P Malfertheiner, R Isenmann, H Kühne, H G Beger, M W Büchler. The risk of pancreaticointestinal anastomosis can be predicted preoperatively.
Pancreas.
1996 Aug; 13(2):202-8. doi:
NULL. [PMID: 8829190] - J E Domínguez-Muñoz, C Hieronymus, T Sauerbruch, P Malfertheiner. Fecal elastase test: evaluation of a new noninvasive pancreatic function test.
The American journal of gastroenterology.
1995 Oct; 90(10):1834-7. doi:
. [PMID: 7572904] - E Małecka-Panas, A Juszyński, J Chrzastek, G Krysiak, W Torzecka. [Comparison of three indirect pancreatic function tests in severe chronic pancreatitis--personal observations].
Polskie Archiwum Medycyny Wewnetrznej.
1995 Oct; 94(4):315-23. doi:
NULL. [PMID: 8834125] - M R Green, S Austin, P McClean, S Jolliffe, L T Weaver. Spot urine pancreolauryl test for use in infancy.
Archives of disease in childhood.
1995 Mar; 72(3):233-4. doi:
10.1136/adc.72.3.233. [PMID: 7741571] - M Fuchs, H Köhler, A Schafmayer. [Effect of various methods of resection of the stomach in liberation of cholecystokinin, neurotensin and on pancreatic function].
Zentralblatt fur Chirurgie.
1995; 120(6):472-7. doi:
NULL. [PMID: 7639036] - J E Domínguez-Muñoz, O Pieramico, M Büchler, P Malfertheiner. Clinical utility of the serum pancreolauryl test in diagnosis and staging of chronic pancreatitis.
The American journal of gastroenterology.
1993 Aug; 88(8):1237-41. doi:
NULL. [PMID: 7687820] - M R Green, S Austin, L T Weaver. Dual marker one day pancreolauryl test.
Archives of disease in childhood.
1993 May; 68(5):649-52. doi:
10.1136/adc.68.5.649. [PMID: 8323334] - L Duntas, B Glasbrenner, C Wolf, O Pieramico, M Büchler, P Malfertheiner. TRH-immunoreactivity in chronic pancreatitis.
Hepato-gastroenterology.
1992 Oct; 39(5):413-6. doi:
NULL. [PMID: 1459520] - J Sarles. [Current techniques for investigating exocrine pancreatic function in children].
Annales de pediatrie.
1992 Apr; 39(4):221-5. doi:
NULL. [PMID: 1616235] - L M Burrell, E J Boyd, K G Wormsley. Is the fluorescein dilaurate test suitable for monitoring the effectiveness of pancreatic enzyme replacement therapy?.
Scandinavian journal of clinical and laboratory investigation.
1991 Dec; 51(8):675-80. doi:
10.3109/00365519109104580. [PMID: 1725463] - M Otte. [Diagnostic value of direct and indirect pancreatic function tests in chronic pancreatitis].
Deutsche medizinische Wochenschrift (1946).
1989 Oct; 114(43):1662-4. doi:
10.1055/s-2008-1066812. [PMID: 2806097] - P Kibat, H Stricker. [Factors of elimination of liposome-encapsulated drug model substances after intravenous administration].
Arzneimittel-Forschung.
1988 Oct; 38(10):1472-8. doi:
NULL. [PMID: 3196388] - P G Lankisch, J Otto, J Brauneis, R Hilgers, B Lembcke. Detection of pancreatic steatorrhea by oral pancreatic function tests.
Digestive diseases and sciences.
1988 Oct; 33(10):1233-6. doi:
10.1007/bf01536672. [PMID: 3262493] - P Malfertheiner, M Büchler, A Müller, H Ditschuneit. [The fluorescein dilaurate serum test following metoclopramide and secretin stimulation for evaluating pancreatic function. Contribution to the diagnosis of chronic pancreatitis].
Zeitschrift fur Gastroenterologie.
1987 Apr; 25(4):225-32. doi:
. [PMID: 3590900] - S Scharpé, L Iliano. Two indirect tests of exocrine pancreatic function evaluated.
Clinical chemistry.
1987 Jan; 33(1):5-12. doi:
10.1093/clinchem/33.1.5. [PMID: 3542296] - P Malfertheiner, M Büchler, A Müller, H Ditschuneit. Fluorescein dilaurate serum test: a rapid tubeless pancreatic function test.
Pancreas.
1987; 2(1):53-60. doi:
10.1097/00006676-198701000-00009. [PMID: 3575314] - D Rosemeyer, P Brackmann, H de Boer, J Freitag, D K Koblitz, K Müller. [1,000 pancreolauryl tests: evaluation of sensitivity, specificity and use in clinical routine].
Zeitschrift fur Gastroenterologie.
1986 Oct; 24(10):635-44. doi:
NULL. [PMID: 3788229] - J G Cumming, J S Forsyth, E J Boyd, G J Frost, A Cuschieri. Diagnosis of exocrine pancreatic insufficiency in cystic fibrosis by use of fluorescein dilaurate test.
Archives of disease in childhood.
1986 Jun; 61(6):573-5. doi:
10.1136/adc.61.6.573. [PMID: 3729527] - P G Lankisch, J Brauneis, J Otto, B Göke. Pancreolauryl and NBT-PABA tests. Are serum tests more practicable alternatives to urine tests in the diagnosis of exocrine pancreatic insufficiency?.
Gastroenterology.
1986 Feb; 90(2):350-4. doi:
. [PMID: 3484456] - J Keller, J Ornsholt, F Andersen, V Munck. Reproducibility of the fluorescein dilaurate pancreatic function test.
Scandinavian journal of clinical and laboratory investigation.
1985 Nov; 45(7):585-8. doi:
10.3109/00365518509155264. [PMID: 4070959] - E J Boyd. Pancreatic function tests in the diagnosis of chronic pancreatitis--current status.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.
1985 Sep; 68(7):495-8. doi:
NULL. [PMID: 3901323] - G Cavallini, W Piubello, G Brocco, R Micciolo, G Chech, G Angelini, L Benini, A Riela, L Dalle Molle, I Vantini. Serum PABA and fluorescein in the course of Bz-Ty-PABA and pancreolauryl test as an index of exocrine pancreatic insufficiency.
Digestive diseases and sciences.
1985 Jul; 30(7):655-63. doi:
10.1007/bf01308415. [PMID: 3874051] - S Gil, E Galván, G Robles-Díaz, L Uscanga, L Alvarez, J C Ramírez. [Available, easy and useful tests for the diagnosis of chronic pancreatitis].
Revista de gastroenterologia de Mexico.
1985 Jul; 50(3):213-8. doi:
NULL. [PMID: 2417300] - R E Barry, W A Behrendt. Studies on the pharmacokinetics of fluorescein and its dilaurate ester under the conditions of the fluorescein dilaurate test.
Arzneimittel-Forschung.
1985; 35(3):644-8. doi:
NULL. [PMID: 4039592] - G Robles-Díaz, M Chávez, E Galván, L Uscanga, E Wolpert. [The fluorescein dilaurate test in the diagnosis of chronic pancreatitis].
Revista de gastroenterologia de Mexico.
1984 Oct; 49(4):215-9. doi:
NULL. [PMID: 6531599] - P G Lankisch, B Lembcke. Indirect pancreatic function tests: chemical and radioisotope methods.
Clinics in gastroenterology.
1984 Sep; 13(3):717-37. doi:
NULL. [PMID: 6386238] - P G Lankisch, A Schreiber, J Otto. Pancreolauryl test. Evaluation of a tubeless pancreatic function test in comparison with other indirect and direct tests for exocrine pancreatic function.
Digestive diseases and sciences.
1983 Jun; 28(6):490-3. doi:
10.1007/bf01308149. [PMID: 6602697] - R E Barry, R Barry, M D Ene, G Parker. Fluorescein dilaurate--tubeless test for pancreatic exocrine failure.
Lancet (London, England).
1982 Oct; 2(8301):742-4. doi:
10.1016/s0140-6736(82)90924-2. [PMID: 6125813] - P G Lankisch. Tubeless pancreatic function tests.
Hepato-gastroenterology.
1981 Dec; 28(6):333-8. doi:
NULL. [PMID: 6178672]
