Ardisiacrispin A (BioDeep_00000176184)

human metabolite PANOMIX_OTCML-2023 blood metabolite natural product

代谢物信息卡片

化学式: C52H84O22 (1060.5454)
中文名称: 百两金素A
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1(C2CCC3(C(C2(CCC1OC4C(C(C(CO4)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(CO6)O)O)O)O)OC7C(C(C(C(O7)CO)O)O)O)C)CCC89C3(CC(C1(C8CC(CC1)(C)C=O)CO9)O)C)C)C
InChI: InChI=1S/C52H84O22/c1-46(2)27-7-11-49(5)28(8-12-52-29-15-47(3,21-55)13-14-51(29,22-68-52)30(57)16-50(49,52)6)48(27,4)10-9-31(46)72-44-40(74-43-39(65)36(62)33(59)24(17-53)69-43)35(61)26(20-67-44)71-45-41(37(63)34(60)25(18-54)70-45)73-42-38(64)32(58)23(56)19-66-42/h21,23-45,53-54,56-65H,7-20,22H2,1-6H3

描述信息

Ardisiacrispin A (Deglucocyclamin) is a common triterpenoid saponin from Ardisia species. Ardisiacrispin A has similar biological properties with some triterpenoid saponins in A. crenata which is one of the species of genus Ardisia and exhibits cytotoxic effect on tumor cells, immunomodulatory and antiviral activities[1].
Ardisiacrispin A (Deglucocyclamin) is a common triterpenoid saponin from Ardisia species. Ardisiacrispin A has similar biological properties with some triterpenoid saponins in A. crenata which is one of the species of genus Ardisia and exhibits cytotoxic effect on tumor cells, immunomodulatory and antiviral activities[1].

同义名列表

7 个代谢物同义名

10-[(5-{[4,5-dihydroxy-6-(hydroxymethyl)-3-[(3,4,5-trihydroxyoxan-2-yl)oxy]oxan-2-yl]oxy}-4-hydroxy-3-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl)oxy]-2-hydroxy-4,5,9,9,13,20-hexamethyl-24-oxahexacyclo[15.5.2.0¹,¹⁸.0⁴,¹⁷.0⁵,¹⁴.0⁸,¹³]tetracosane-20-carbaldehyde; 3 beta-O-(beta-D-xylopyranosyl-(1-2)-O-beta-D-glucopyranosyl-(1-4)-(O-beta-D-glucopyranosyl-(1-2))-alpha-L-arabinopyranosyl)-16 alpha-hydroxy-13 beta,28-epoxyolean-30-al; Ardisiacrispin A; CID 14019197; Deglucocyclamin; LTS-4; Saxifragifolin B

数据库引用编号

7 个数据库交叉引用编号

PubChem: 14019197
HMDB: HMDB0248569
KNApSAcK: C00050053
CAS: 23643-61-0
PMhub: MS000104431
medchemexpress: HY-N0206
LOTUS: LTS0028095

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

58 个相关的物种来源信息

85163 - Androsace: LTS0028095
229443 - Androsace integra: 10.1016/J.FITOTE.2011.04.001
229443 - Androsace integra: LTS0028095
265254 - Androsace umbellata: 10.1055/S-2008-1081291
265254 - Androsace umbellata: LTS0028095
13344 - Ardisia: LTS0028095
13345 - Ardisia crenata: 10.1002/HLCA.201000285
13345 - Ardisia crenata: 10.1016/S0031-9422(00)90418-7
13345 - Ardisia crenata: LTS0028095
13345 - Ardisia crenata Sims: -
59973 - Cyclamen: LTS0028095
87515 - Cyclamen africanum: 10.1016/0031-9422(89)80123-2
87515 - Cyclamen africanum: LTS0028095
87516 - Cyclamen balearicum: 10.1016/0031-9422(89)80123-2
87516 - Cyclamen balearicum: LTS0028095
87517 - Cyclamen cilicium: LTS0028095
87519 - Cyclamen coum: 10.1016/0031-9422(89)80123-2
87519 - Cyclamen coum: 10.1055/S-2006-957637
87519 - Cyclamen coum: LTS0028095
87520 - Cyclamen coum subsp. coum: 10.1055/S-2006-957637
87520 - Cyclamen coum subsp. coum: LTS0028095
87523 - Cyclamen creticum: 10.1016/0031-9422(89)80123-2
87523 - Cyclamen creticum: LTS0028095
87524 - Cyclamen cyprium: 10.1016/0031-9422(89)80123-2
87524 - Cyclamen cyprium: LTS0028095
87525 - Cyclamen graecum: 10.1016/0031-9422(89)80123-2
87525 - Cyclamen graecum: LTS0028095
59974 - Cyclamen hederifolium: LTS0028095
87528 - Cyclamen mirabile: 10.1016/0031-9422(89)80123-2
87528 - Cyclamen mirabile: 10.1021/NP960658J
87528 - Cyclamen mirabile: LTS0028095
87530 - Cyclamen persicum: 10.1016/0031-9422(89)80123-2
87530 - Cyclamen persicum: LTS0028095
87531 - Cyclamen pseudibericum: 10.1016/0031-9422(89)80123-2
87531 - Cyclamen pseudibericum: LTS0028095
87532 - Cyclamen purpurascens: 10.1016/0031-9422(89)80123-2
87532 - Cyclamen purpurascens: LTS0028095
87533 - Cyclamen repandum: 10.1016/J.CARRES.2009.12.028
87533 - Cyclamen repandum: LTS0028095
2759 - Eukaryota: LTS0028095
9606 - Homo sapiens: -
396391 - Labisia: LTS0028095
396393 - Labisia pumila: 10.1016/J.PHYTOCHEM.2011.06.014
396393 - Labisia pumila: LTS0028095
59977 - Lysimachia: LTS0028095
1043457 - Lysimachia patungensis: 10.1007/S10600-007-0071-8
1043457 - Lysimachia patungensis: LTS0028095
3398 - Magnoliopsida: LTS0028095
16614 - Myrsinaceae: LTS0028095
59981 - Myrsine: LTS0028095
33090 - Plants: -
49647 - Primula: LTS0028095
175055 - Primula denticulata: 10.1016/0031-9422(88)80644-7
175055 - Primula denticulata: LTS0028095
4335 - Primulaceae: LTS0028095
35493 - Streptophyta: LTS0028095
58023 - Tracheophyta: LTS0028095
33090 - Viridiplantae: LTS0028095

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表

文献列表

Irma Podolak, Barbara Żuromska-Witek, Karolina Grabowska, Sara Żebrowska, Agnieszka Galanty, Urszula Hubicka. Comparative Quantitative Study of Ardisiacrispin A in Extracts from Ardisia crenata Sims Varieties and Their Cytotoxic Activities. Chemistry & biodiversity. 2021 Jul; 18(7):e2100335. doi: 10.1002/cbdv.202100335. [PMID: 34089236]
Bingmu Fang, Shihui Bao, Shuanghu Wang, Minle Chen, Bingbao Chen, Ke Su, Congcong Wen, Yunfang Zhou, Xianqin Wang, Yuepeng Jin. Pharmacokinetic study of ardisiacrispin A in rat plasma after intravenous administration by UPLC-MS/MS. Biomedical chromatography : BMC. 2017 Mar; 31(3):. doi: 10.1002/bmc.3826. [PMID: 27565758]
Weiwei Dong, Xin Liu, Xiaobo Li, Dajian Yang, Lisheng Ding. A new triterpene saponin from Androsace integra. Fitoterapia. 2011 Jul; 82(5):782-5. doi: 10.1016/j.fitote.2011.04.001. [PMID: 21497642]
Z Jia, K Koike, T Ohmoto, M Ni. Triterpenoid saponins from Ardisia crenata. Phytochemistry. 1994 Nov; 37(5):1389-96. doi: 10.1016/s0031-9422(00)90418-7. [PMID: 7765756]
C Jansakul, H Baumann, L Kenne, G Samuelsson. Ardisiacrispin A and B, two utero-contracting saponins from Ardisia crispa. Planta medica. 1987 Oct; 53(5):405-9. doi: 10.1055/s-2006-962758. [PMID: 3432422]