anhydroretinol (BioDeep_00000019639)

 

Secondary id: BioDeep_00001871571

human metabolite PANOMIX_OTCML-2023


代谢物信息卡片


(6E)-6-[(2E,4E,6E)-3,7-dimethylnona-2,4,6,8-tetraen-1-ylidene]-1,5,5-trimethylcyclohex-1-ene

化学式: C20H28 (268.2190888)
中文名称:
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 5.26%

分子结构信息

SMILES: C=CC(C)=CC=CC(C)=CC=C1C(C)=CCCC1(C)C
InChI: InChI=1S/C20H28/c1-7-16(2)10-8-11-17(3)13-14-19-18(4)12-9-15-20(19,5)6/h7-8,10-14H,1,9,15H2,2-6H3/b11-8+,16-10+,17-13+,19-14-

描述信息

anhydroretinol, also known as Anhydrovitamin a, is classified as a member of the Sesquiterpenoids. Sesquiterpenoids are terpenes with three consecutive isoprene units
D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids
all-trans-Anhydro Retinol (Anhydrovitamin A) is a metabolite of Vitamin A. all-trans-Anhydro Retinol is used in synthetic multivitamin preparations[1].

同义名列表

6 个代谢物同义名

(6E)-6-[(2E,4E,6E)-3,7-dimethylnona-2,4,6,8-tetraen-1-ylidene]-1,5,5-trimethylcyclohex-1-ene; Vitamin A Impurity B (Anhydro-Vitamin A); trans-Anhydrovitamin a; Anhydrovitamin a; anhydroretinol; all-trans-Anhydro Retinol



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ulrich Hammerling, Youn-Kyung Kim, Loredana Quadro. Quantum chemistry rules retinoid biology. Communications biology. 2023 02; 6(1):227. doi: 10.1038/s42003-023-04602-x. [PMID: 36854887]
  • Ulrich Hammerling. Vitamin A as PKC Co-factor and Regulator of Mitochondrial Energetics. Sub-cellular biochemistry. 2016 ; 81(?):201-230. doi: 10.1007/978-94-024-0945-1_8. [PMID: 27830506]
  • Beatrice Hoyos, Rebeca Acin-Perez, Donald A Fischman, Giovanni Manfredi, Ulrich Hammerling. Hiding in plain sight: uncovering a new function of vitamin A in redox signaling. Biochimica et biophysica acta. 2012 Jan; 1821(1):241-7. doi: 10.1016/j.bbalip.2011.06.014. [PMID: 21763457]
  • J J Yin, Q Xia, P P Fu. UVA photoirradiation of anhydroretinol--formation of singlet oxygen and superoxide. Toxicology and industrial health. 2007 Nov; 23(10):625-31. doi: 10.1177/0748233708090909. [PMID: 18717521]
  • Qingsu Xia, Jun Jie Yin, Shu-Hui Cherng, Wayne G Wamer, Mary Boudreau, Paul C Howard, Peter P Fu. UVA photoirradiation of retinyl palmitate--formation of singlet oxygen and superoxide, and their role in induction of lipid peroxidation. Toxicology letters. 2006 May; 163(1):30-43. doi: 10.1016/j.toxlet.2005.09.010. [PMID: 16384671]
  • G E Mao, M D Collins, F Derguini. Teratogenicity, tissue distribution, and metabolism of the retro-retinoids, 14-hydroxy-4,14-retro-retinol and anhydroretinol, in the C57BL/6J mouse. Toxicology and applied pharmacology. 2000 Feb; 163(1):38-49. doi: 10.1006/taap.1999.8828. [PMID: 10662603]
  • Y F Shealy, D L Hill, B P Sani, I Eto, M M Juliana, C J Crubbs. Anhydroretinol, a retinoid active in preventing mammary cancer induced in rats by N-methyl-N-nitrosourea. Oncology reports. 1998 Jul; 5(4):857-60. doi: 10.3892/or.5.4.857. [PMID: 9625832]
  • T M Eppinger, J Buck, U Hämmerling. Growth control or terminal differentiation: endogenous production and differential activities of vitamin A metabolites in HL-60 cells. The Journal of experimental medicine. 1993 Dec; 178(6):1995-2005. doi: 10.1084/jem.178.6.1995. [PMID: 8245778]
  • M E Cullum, M H Zile, S W Veysey. Analysis of retinol and dideuterated retinol in rat plasma by gas chromatography combined mass spectrometry. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 1984; 54(1):11-6. doi: NULL. [PMID: 6376395]
  • M E Cullum, J A Olson, S W Veysey. Analysis of deuterated analogs of vitamin A by electron impact and chemical ionization modes in gas chromatography coupled to mass spectrometry. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 1984; 54(1):3-10. doi: NULL. [PMID: 6735613]