L-1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid (BioDeep_00000019176)

Main id: BioDeep_00000619946

 

human metabolite


代谢物信息卡片


1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid, (S)-isomer

化学式: C12H12N2O2 (216.0898732)
中文名称: (S)-2,3,4,9-四氢-1H-吡啶[3,4-b]吲哚-3-羧酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c12c(c3c([nH]1)CN[C@@H](C3)C(=O)O)cccc2
InChI: InChI=1S/C12H12N2O2/c15-12(16)10-5-8-7-3-1-2-4-9(7)14-11(8)6-13-10/h1-4,10,13-14H,5-6H2,(H,15,16)

描述信息

L-1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid is found in garden tomato (var.). L-1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid is widespread in many foodstuffs especially fruit juices, jams and fermented foods or beverages. L-1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid is formed by Pictet-Spengler condensation of L-tryptophan and formaldehyde in nature or during food processin
Widespread in many foodstuffs especially fruit juices, jams and fermented foods or beverages. Formed by Pictet-Spengler condensation of L-tryptophan and formaldehyde in nature or during food processing. L-1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid is found in garden tomato (variety).

同义名列表

27 个代谢物同义名

1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid, (S)-isomer; 1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid,(+-)-isomer; L-1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid; 1H,2H,3H,4H,9H-pyrido[3,4-b]indole-3-carboxylic acid; 1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid; L-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic acid; L-1,2,3,4-Tetrahydro-b-carboline-3-carboxylic acid; L-1,2,3,4-Tetrahydro-beta-carboline-3-carboxylate; 1,2,3,4-Tetrahydro-b-carboline-3-carboxylic acid; 1,2,3,4-Tetrahydro-β-carboline-3-carboxylic acid; (-)-3-Carboxy-1,2,3,4-tetrahydro-beta-carboline; L-1,2,3,4-Tetrahydronorharman-3-carboxylic acid; 1,2,3,4-Tetrahydro-beta-carboline-3-carboxylate; L-1,2,3,4-Tetrahydro-β-carboline-3-carboxylate; L-1,2,3,4-Tetrahydro-b-carboline-3-carboxylate; 3S-Tetrahydro-beta-carboline-3-carboxylic acid; 1,2,3,4-Tetrahydro-b-carboline-3-carboxylate; 1,2,3,4-Tetrahydro-β-carboline-3-carboxylate; 3-Carboxy-1,2,3,4-tetrahydro-beta-carboline; 3-Carboxy-1,2,3,4-tetrahydro-2-carboline; Cyclomethyltryptophan; Lycoperodine 1; Lycoperodine; CCRIS 6486; NSC 96912; THBC-CA; tnca



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Xiaomin Wang, Rui Liu, Yukun Yang, Min Zhang. Isolation, purification and identification of antioxidants in an aqueous aged garlic extract. Food chemistry. 2015 Nov; 187(?):37-43. doi: 10.1016/j.foodchem.2015.03.109. [PMID: 25976995]
  • Hong-jian Song, Yong-xian Liu, Yu-xiu Liu, Yuan-qiong Huang, Yong-qiang Li, Qing-min Wang. Design, synthesis, anti-TMV, fungicidal, and insecticidal activity evaluation of 1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid derivatives based on virus inhibitors of plant sources. Bioorganic & medicinal chemistry letters. 2014 Nov; 24(22):5228-33. doi: 10.1016/j.bmcl.2014.09.063. [PMID: 25442317]
  • Tomás Herraiz, Juan Galisteo. Naturally-occurring tetrahydro-β-carboline alkaloids derived from tryptophan are oxidized to bioactive β-carboline alkaloids by heme peroxidases. Biochemical and biophysical research communications. 2014 Aug; 451(1):42-7. doi: 10.1016/j.bbrc.2014.07.047. [PMID: 25035927]
  • Jan Stanstrup, Simon S Schou, Jens Holmer-Jensen, Kjeld Hermansen, Lars O Dragsted. Whey protein delays gastric emptying and suppresses plasma fatty acids and their metabolites compared to casein, gluten, and fish protein. Journal of proteome research. 2014 May; 13(5):2396-408. doi: 10.1021/pr401214w. [PMID: 24708224]
  • Fu-Xin Wang, An-Jun Deng, Ming Li, Jin-Feng Wei, Hai-Lin Qin, Ai-Ping Wang. (3S)-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic acid from Cichorium endivia. L induces apoptosis of human colorectal cancer HCT-8 cells. Molecules (Basel, Switzerland). 2012 Dec; 18(1):418-29. doi: 10.3390/molecules18010418. [PMID: 23275050]
  • An Choudhary, Ms Kohli, A Kumar, A Joshi. Synthesis of tryptoline-3-carboxylic Acid derivatives a novel antidiabetic agent. Journal of young pharmacists : JYP. 2011 Apr; 3(2):132-7. doi: 10.4103/0975-1483.80302. [PMID: 21731359]
  • Yong-Qin Yin, Zhi-Bin Shen, Ling-Yi Kong. [Studies on chemical constituents from Ipomoea batatas]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2008 Oct; 31(10):1501-3. doi: ". [PMID: 19230398]
  • Yi He, Ya-jian Guo, Yun-yan Gao. [Studies on chemical constituents of root of Cichorium intybus]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2002 Mar; 27(3):209-10. doi: ". [PMID: 12774404]
  • G K Tóth, K Bakos, B Penke, I Pávó, C Varga, G Török, A Péter, F Fülöp. Synthesis of oxytocin antagonists containing conformationally constrained amino acids in position 2. Bioorganic & medicinal chemistry letters. 1999 Mar; 9(5):667-72. doi: 10.1016/s0960-894x(99)00041-4. [PMID: 10201826]
  • J Adachi, Y Ueno, Y Ogawa, S Hishida, K Yamamoto, H Ouchi, Y Tatsuno. Acetaldehyde-induced formation of 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid in rats. Biochemical pharmacology. 1993 Feb; 45(4):935-41. doi: 10.1016/0006-2952(93)90179-z. [PMID: 8452569]
  • J Adachi, Y Mizoi, T Naito, Y Ogawa, Y Uetani, I Ninomiya. Identification of tetrahydro-beta-carboline-3-carboxylic acid in foodstuffs, human urine and human milk. The Journal of nutrition. 1991 May; 121(5):646-52. doi: 10.1093/jn/121.5.646. [PMID: 2019874]