Cyclo-prolylglycine (BioDeep_00000017730)

 

Secondary id: BioDeep_00000171413, BioDeep_00000179750, BioDeep_00000278286

human metabolite PANOMIX_OTCML-2023 blood metabolite


代谢物信息卡片


(S)-Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, Cyclo-Gly-Pro, CYCLO(-GLY-PRO)

化学式: C7H10N2O2 (154.07422400000002)
中文名称: 六氢吡咯并[1,2-a]吡嗪-1,4-二酮
谱图信息: 最多检出来源 Homo sapiens(blood) 2.71%

分子结构信息

SMILES: C1CC2C(=O)NCC(=O)N2C1
InChI: InChI=1S/C7H10N2O2/c10-6-4-8-7(11)5-2-1-3-9(5)6/h5H,1-4H2,(H,8,11)

描述信息

Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid.
Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione is a natural product found in Streptomyces antioxidans, Streptomyces nigra, and Streptomyces xanthophaeus with data available.
Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione is a natural product found in Streptomyces antioxidans, Streptomyces nigra, and Streptomyces xanthophaeus with data available.
Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione), an alkaloid isolated from green algae Ulva prolifera, possesses antialgal activity against the common harmful red tide microalgae[1]. Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione) possesses antiamnesic effects and neuroprotective actions[2].

同义名列表

17 个代谢物同义名

(S)-Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, Cyclo-Gly-Pro, CYCLO(-GLY-PRO); 2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione; Pyrrolo(1,2-a)pyrazine-1,4-dione, hexahydro-, (S)-; Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-; octahydropyrrolo[1,2-a]piperazine-1,4-dione; Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione; Pyrrolidino[1,2-a]piperazine-3,6-dione; cyclo(glycylprolyl), (L)-isomer; Cyclo-Gly-Pro, >=98\\% (GC/HPLC); cyclo(glycyl-L-prolyl); cyclo(glycylprolyl); Cyclo-prolylglycine; cyclo(Gly-O-Pro); Cyclo-(Pro-Gly); cyclo(Gly-Pro); Cyclo(pro-gly); Pyrrolopiperazine-2,5-dione



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Z-F Wu, G-L Liu, Z Zhou, G-X Wang, L Xia, J-L Liu. Induction of immune-related gene expression in Ctenopharyngodon idella kidney cells by secondary metabolites from immunostimulatory Alcaligenes faecalis FY-3. Scandinavian journal of immunology. 2012 Aug; 76(2):131-40. doi: 10.1111/j.1365-3083.2012.02722.x. [PMID: 22606987]
  • J Liu, Y Lei, F Wang, Y Yi, Y Liu, G Wang. Immunostimulatory activities of specific bacterial secondary metabolite of Anoxybacillus flavithermus strain SX-4 on carp, Cyprinus carpio. Journal of applied microbiology. 2011 Apr; 110(4):1056-64. doi: 10.1111/j.1365-2672.2011.04963.x. [PMID: 21294820]
  • J Guan, S Mathai, P Harris, J-Y Wen, R Zhang, M Brimble, P Gluckman. Peripheral administration of a novel diketopiperazine, NNZ 2591, prevents brain injury and improves somatosensory-motor function following hypoxia-ischemia in adult rats. Neuropharmacology. 2007 Nov; 53(6):749-62. doi: 10.1016/j.neuropharm.2007.08.010. [PMID: 17904590]