Rebaudioside A (BioDeep_00000017274)

 

Secondary id: BioDeep_00000395089

human metabolite PANOMIX_OTCML-2023 Endogenous natural product


代谢物信息卡片


(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl (1R,4S,5R,9S,10R,13S)-13-{[(2S,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis({[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy})oxan-2-yl]oxy}-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.0^{1,10}.0^{4,9}]hexadecane-5-carboxylate

化学式: C44H70O23 (966.4308)
中文名称: 甜菊双糖苷 A, 甜菊双糖甙 A, A 甙甜菊糖, 莱苞迪甙 A, 瑞鲍迪甙 A, 莱苞迪甙A, 甜菊苷
谱图信息: 最多检出来源 Viridiplantae(plant) 94.46%

分子结构信息

SMILES: C=C1CC23CCC4C(C)(C(=O)OC5OC(CO)C(O)C(O)C5O)CCCC4(C)C2CCC1(OC1OC(CO)C(O)C(OC2OC(CO)C(O)C(O)C2O)C1OC1OC(CO)C(O)C(O)C1O)C3
InChI: InChI=1S/C44H70O23/c1-17-11-43-9-5-22-41(2,7-4-8-42(22,3)40(59)66-38-33(58)30(55)26(51)20(14-47)62-38)23(43)6-10-44(17,16-43)67-39-35(65-37-32(57)29(54)25(50)19(13-46)61-37)34(27(52)21(15-48)63-39)64-36-31(56)28(53)24(49)18(12-45)60-36/h18-39,45-58H,1,4-16H2,2-3H3/t18-,19-,20-,21-,22+,23+,24-,25-,26-,27-,28+,29+,30+,31-,32-,33-,34+,35-,36+,37+,38+,39+,41-,42-,43-,44+/m1/s1

描述信息

Rebaudioside A is a rebaudioside that is rubusoside in which the hydroxy groups at positions 3 and 4 of the beta-D-glucopyranosyloxy group at the 13alpha position have both been converted to the corresponding beta-D-glucopyranoside. It has a role as a sweetening agent. It is a beta-D-glucoside, a tetracyclic diterpenoid and a rebaudioside. It is functionally related to a rubusoside and a beta-D-Glcp-(1->2)-[beta-D-Glcp-(1->3)]-beta-D-Glcp.
Rebaudioside A is under investigation in clinical trial NCT03510624 (Acute Effect of Rebaudioside A on Glucose Excursion During an Oral Glucose Tolerance Test in Type 2 Diabetes Mellitus).
Rebaudioside A is a natural product found in Stevia rebaudiana and Bos taurus with data available.
See also: Stevia rebaudiuna Leaf (part of).
Rebaudioside A belongs to the class of organic compounds known as steviol glycosides. These are prenol lipids containing a carbohydrate moiety glycosidically linked to a steviol (a diterpenoid based on a 13-hydroxykaur-16-en-18-oic acid) moiety. Rebaudioside A is an extremely weak basic (essentially neutral) compound (based on its pKa). Rebaudioside A is a constituent of Stevia rebaudiana (stevia). Rebaudioside B, D, and E may also be present in minute quantities; however, it is suspected that rebaudioside B is a byproduct of the isolation technique. The two major compounds stevioside and rebaudioside, primarily responsible for the sweet taste of stevia leaves, were first isolated by two French chemists in 1931.
A rebaudioside that is rubusoside in which the hydroxy groups at positions 3 and 4 of the beta-D-glucopyranosyloxy group at the 13alpha position have both been converted to the corresponding beta-D-glucopyranoside.
Constituent of Stevia rebaudiana (stevia)
Rebaudioside A is a steviol glycoside and α-glucosidase inhibitor with an IC50 of 35.01 ug/mL.
Rebaudioside A is a steviol glycoside and α-glucosidase inhibitor with an IC50 of 35.01 ug/mL.

同义名列表

57 个代谢物同义名

(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl (1R,4S,5R,9S,10R,13S)-13-{[(2S,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis({[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy})oxan-2-yl]oxy}-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.0^{1,10}.0^{4,9}]hexadecane-5-carboxylate; (2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl (1R,4S,5R,9S,10R,13S)-13-{[(2S,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis({[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy})oxan-2-yl]oxy}-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecane-5-carboxylic acid; [(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,4S,5R,9S,10R,13S)-13-[(2S,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]oxan-2-yl]oxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylate; [(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl](1R,4S,5R,9S,10R,13S)-13-[(2S,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]oxan-2-yl]oxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylate; 1-O-(13alpha-{[beta-D-glucopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->3)]-beta-D-glucopyranosyl]oxy}-18-oxo-5beta,8alpha,9beta,10alpha-kaur-16-en-18-yl)-beta-D-glucopyranose; 1-O-(13alpha-((beta-D-glucopyranosyl-(1->2)-(beta-D-glucopyranosyl-(1->3))-beta-D-glucopyranosyl)oxy)-18-oxo-5beta,8alpha,9beta,10alpha-kaur-16-en-18-yl)-beta-D-glucopyranose; (4.ALPHA.)-13-((O-.BETA.-D-GLUCOPYRANOSYL-(1->2)-O-(.BETA.-D-GLUCOPYRANOSYL-(1->3))-.BETA.-D-GLUCOPYRANOSYL)OXY)KAUR-16-EN-18-OIC ACID .BETA.-D-GLUCOPYRANOSYL ESTER; (4alpha)-13-((O-beta-D-GLUCOPYRANOSYL-(1->2)-O-(beta-D-GLUCOPYRANOSYL-(1->3))-beta-D-GLUCOPYRANOSYL)OXY)KAUR-16-EN-18-OIC ACID beta-D-GLUCOPYRANOSYL ESTER; 13-((2-O-beta-D-glucopyranosyl-3-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)-ent-kaur-16-en-19-oic acid beta-D-glucopyranosyl ester; 13-[(2-O-beta-D-glucopyranosyl-3-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-ent-kaur-16-en-19-oic acid beta-D-glucopyranosyl ester; 19-O-beta-glucopyranosyl-13-O-(beta-glucopyranosyl(1-2)-beta-glucopyranosyl(1-3))-beta-glucopyranosyl-13-hydroxykaur-16-en-19-oic acid; 13-[(2-O-beta-D-Glucopyranosyl-3-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-ent-kaur-16-en-19-Oate beta-D-glucopyranosyl ester; 19-O-beta-Glucopyranosyl-13-O-(beta-glucopyranosyl(1-2)-beta-glucopyranosyl(1-3))-beta-glucopyranosyl-13-hydroxykaur-16-en-19-Oate; 13-[(2-O-Β-D-glucopyranosyl-3-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-ent-kaur-16-en-19-Oic acid β-D-glucopyranosyl ester; 13-[(2-O-b-D-Glucopyranosyl-3-O-b-D-glucopyranosyl-b-D-glucopyranosyl)oxy]-ent-kaur-16-en-19-Oic acid b-D-glucopyranosyl ester; 13-[(2-O-Β-D-glucopyranosyl-3-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-ent-kaur-16-en-19-Oate β-D-glucopyranosyl ester; 19-O-b-Glucopyranosyl-13-O-(b-glucopyranosyl(1-2)-b-glucopyranosyl(1-3))-b-glucopyranosyl-13-hydroxykaur-16-en-19-Oic acid; 13-[(2-O-b-D-Glucopyranosyl-3-O-b-D-glucopyranosyl-b-D-glucopyranosyl)oxy]-ent-kaur-16-en-19-Oate b-D-glucopyranosyl ester; 19-O-Β-glucopyranosyl-13-O-(β-glucopyranosyl(1-2)-β-glucopyranosyl(1-3))-β-glucopyranosyl-13-hydroxykaur-16-en-19-Oic acid; 19-O-b-Glucopyranosyl-13-O-(b-glucopyranosyl(1-2)-b-glucopyranosyl(1-3))-b-glucopyranosyl-13-hydroxykaur-16-en-19-Oate; 19-O-Β-glucopyranosyl-13-O-(β-glucopyranosyl(1-2)-β-glucopyranosyl(1-3))-β-glucopyranosyl-13-hydroxykaur-16-en-19-Oate; 19-O-beta-glucopyranosyl-13-O-(beta-glucopyranosyl(1-2)-beta-glucopyranosyl(1-3))-beta-glucopyranosylsteviol; 19-O-Β-glucopyranosyl-13-O-(β-glucopyranosyl(1-2)-β-glucopyranosyl(1-3))-β-glucopyranosylsteviol; 19-O-b-Glucopyranosyl-13-O-(b-glucopyranosyl(1-2)-b-glucopyranosyl(1-3))-b-glucopyranosylsteviol; Rebaudioside A, United States Pharmacopeia (USP) Reference Standard; Rebaudioside A, analytical reference material; Glycoside A3, from Stevia rebaudiana; Rebaudioside A, >=96\\% (HPLC); REBAUDIOSIDE A [USP-RS]; REBAUDIOSIDE A (USP-RS); REBAUDIOSIDE A [INCI]; REBAUDIOSIDE A [FCC]; REBAUDIOSIDE A [MI]; UNII-B3FUD0528F; Sooolite!-Pure; Chrysanta AR-P; Rebaudioside A; Sweetener 4G-S; Rebaudioside-A; REBAUDIOSIDEA; Stevioside A3; Rebaudiana a; Glycoside A3; Rebaudioside; Tox21_200565; Glycoside X; B3FUD0528F; SG 95RA50; Reb-A 97; Pure Via; Rebiana; Stevia; Truvia; Reb-A; Reb A; RA 95; Stevia rebaudiana, ext.



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

10 个相关的代谢反应过程信息。

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BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(10)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

14 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Agata Ptak, Agnieszka Szewczyk, Magdalena Simlat, Alicja Błażejczak, Marzena Warchoł. Meta-Topolin-induced mass shoot multiplication and biosynthesis of valuable secondary metabolites in Stevia rebaudiana Bertoni bioreactor culture. Scientific reports. 2023 09; 13(1):15520. doi: 10.1038/s41598-023-42619-8. [PMID: 37726319]
  • Yuping Li, Yuan Qiu, Xin Xu, Ming Luo. Genome-wide identification of SrbHLH transcription factors highlights its potential role in rebaudioside A (RA) biosynthesis in Stevia rebaudiana. BMC plant biology. 2023 Jul; 23(1):352. doi: 10.1186/s12870-023-04353-1. [PMID: 37415121]
  • Magdalena Simlat, Agata Ptak, Anita Jaglarz, Agnieszka Szewczyk, Michał Dziurka, Artur Gurgul. Seeds of Stevia rebaudiana Bertoni as a Source of Plant Growth-Promoting Endophytic Bacteria with the Potential to Synthesize Rebaudioside A. International journal of molecular sciences. 2023 Jan; 24(3):. doi: 10.3390/ijms24032174. [PMID: 36768498]
  • F Kh Kamilov, I G Konkina, V N Kozlov, T I Ganeev, L A Badykova, A N Kryachko. [Evaluation of the nanosize and stability of aqueous dispersions of iodinecontaining conjugates based on carriers of plant origin, promising for iodine enrichment of foods]. Voprosy pitaniia. 2022; 91(6):110-117. doi: 10.33029/0042-8833-2022-91-6-110-117. [PMID: 36648189]
  • Nazli Mert Ozupek, Levent Cavas. Modelling of multilinear gradient retention time of bio-sweetener rebaudioside A in HPLC analysis. Analytical biochemistry. 2021 08; 627(?):114248. doi: 10.1016/j.ab.2021.114248. [PMID: 34022188]
  • Luciana M Sergio, Yandara A Martins, Jackson L Amaral, Victor L B França, Camila F de Freitas, Antônio Medina Neto, Noboru Hioka, Maria I Ravanelli, Cecília Mareze-Costa, Sílvio Claudio da Costa, Valder N Freire, Kellen Brunaldi. Molecular insight on the binding of stevia glycosides to bovine serum albumin. Chemico-biological interactions. 2021 Aug; 344(?):109526. doi: 10.1016/j.cbi.2021.109526. [PMID: 34023281]
  • Maria Margarida Ribeiro, Tatiana Diamantino, Joana Domingues, Ílio Montanari, Marcos Nopper Alves, José Carlos Gonçalves. Stevia rebaudiana germplasm characterization using microsatellite markers and steviol glycosides quantification by HPLC. Molecular biology reports. 2021 Mar; 48(3):2573-2582. doi: 10.1007/s11033-021-06308-x. [PMID: 33811576]
  • Liwei Xu, Yuqing Wei, Jiurong Wang, Shaoxun Tang, Chuanshe Zhou, Zhiliang Tan, Xuefeng Han. Effects of the natural sweetener rebaudioside A on intake, nutrient digestion, rumen fermentation, and blood biochemical parameters in adult goats during summer. Animal science journal = Nihon chikusan Gakkaiho. 2021 Jan; 92(1):e13532. doi: 10.1111/asj.13532. [PMID: 33634929]
  • Muhammad Imran Khan, Muhammad Zubair Khan, Jin Hyuk Shin, Tia Sun Shin, Young Bok Lee, Min Yung Kim, Jong Deog Kim. Pharmacological Approaches to Attenuate Inflammation and Obesity with Natural Products Formulations by Regulating the Associated Promoting Molecular Signaling Pathways. BioMed research international. 2021; 2021(?):2521273. doi: 10.1155/2021/2521273. [PMID: 34812408]
  • Jakub Michał Kurek, Ewelina Król, Zbigniew Krejpcio. Steviol Glycosides Supplementation Affects Lipid Metabolism in High-Fat Fed STZ-Induced Diabetic Rats. Nutrients. 2020 Dec; 13(1):. doi: 10.3390/nu13010112. [PMID: 33396905]
  • Victor Markus, Orr Share, Kerem Teralı, Nazmi Ozer, Robert S Marks, Ariel Kushmaro, Karina Golberg. Anti-Quorum Sensing Activity of Stevia Extract, Stevioside, Rebaudioside A and Their Aglycon Steviol. Molecules (Basel, Switzerland). 2020 Nov; 25(22):. doi: 10.3390/molecules25225480. [PMID: 33238612]
  • Zhenyang Wang, Jiefang Hong, Siyuan Ma, Tong Huang, Yuanyuan Ma, Wei Liu, Wenbin Liu, Zhiming Liu, Hao Song. Heterologous expression of EUGT11 from Oryza sativa in Pichia pastoris for highly efficient one-pot production of rebaudioside D from rebaudioside A. International journal of biological macromolecules. 2020 Nov; 163(?):1669-1676. doi: 10.1016/j.ijbiomac.2020.09.132. [PMID: 32976903]
  • Dandan Zhou, Yunting Xu, Yedong Wang, Jiajun Li, Chunshan Gui, Hongjian Zhang. Interaction of Organic Anion Transporter 3-Mediated Uptake of Steviol Acyl Glucuronide, a Major Metabolite of Rebaudioside A, with Selected Drugs. Journal of agricultural and food chemistry. 2020 Feb; 68(6):1579-1587. doi: 10.1021/acs.jafc.9b05808. [PMID: 31760750]
  • Concetta Schiano, Vincenzo Grimaldi, Monica Franzese, Carmela Fiorito, Filomena De Nigris, Francesco Donatelli, Andrea Soricelli, Marco Salvatore, Claudio Napoli. Non-nutritional sweeteners effects on endothelial vascular function. Toxicology in vitro : an international journal published in association with BIBRA. 2020 Feb; 62(?):104694. doi: 10.1016/j.tiv.2019.104694. [PMID: 31655124]
  • Zhifeng Liu, Jianxu Li, Yuwei Sun, Peng Zhang, Yong Wang. Structural Insights into the Catalytic Mechanism of a Plant Diterpene Glycosyltransferase SrUGT76G1. Plant communications. 2020 01; 1(1):100004. doi: 10.1016/j.xplc.2019.100004. [PMID: 33404544]
  • Kavita Ngekure M X, Jingle Jiang, Hamdard Enayatullah, Wael Ennab, Sheeraz Mustafa, Saif Rodeni, Quanwei Wei, Fangxiong Shi. Sweet taste receptor agonists alter ovarian functions and ovarian cycles in aged mice. Reproductive biology. 2019 Sep; 19(3):230-236. doi: 10.1016/j.repbio.2019.07.007. [PMID: 31399370]
  • Concetta Schiano, Vincenzo Grimaldi, Serena Boccella, Monica Iannotta, Alberto Zullo, Livio Luongo, Francesco Paolo Mancini, Sabatino Maione, Claudio Napoli. Sweeteners modulate bioactivity of endothelial progenitor cells but not induce detrimental effects both on inflammation and behavioural changes. International journal of food sciences and nutrition. 2019 Sep; 70(6):725-737. doi: 10.1080/09637486.2018.1563052. [PMID: 30775939]
  • Sael Casas-Grajales, Karina Reyes-Gordillo, Carlos M Cerda-García-Rojas, Víctor Tsutsumi, M Raj Lakshman, Pablo Muriel. Rebaudioside A administration prevents experimental liver fibrosis: an in vivo and in vitro study of the mechanisms of action involved. Journal of applied toxicology : JAT. 2019 08; 39(8):1118-1131. doi: 10.1002/jat.3797. [PMID: 30883860]
  • Jodi E Nettleton, Teja Klancic, Alana Schick, Ashley C Choo, Jane Shearer, Stephanie L Borgland, Faye Chleilat, Shyamchand Mayengbam, Raylene A Reimer. Low-Dose Stevia (Rebaudioside A) Consumption Perturbs Gut Microbiota and the Mesolimbic Dopamine Reward System. Nutrients. 2019 May; 11(6):. doi: 10.3390/nu11061248. [PMID: 31159256]
  • Kelly A Higgins, Richard D Mattes. A randomized controlled trial contrasting the effects of 4 low-calorie sweeteners and sucrose on body weight in adults with overweight or obesity. The American journal of clinical nutrition. 2019 05; 109(5):1288-1301. doi: 10.1093/ajcn/nqy381. [PMID: 30997499]
  • Arman Pazuki, Fatemeh Aflaki, Buhara Yücesan, Songül Gürel. Effects of cytokinins, gibberellic acid 3, and gibberellic acid 4/7 on in vitro growth, morphological traits, and content of steviol glycosides in Stevia rebaudiana. Plant physiology and biochemistry : PPB. 2019 Apr; 137(?):154-161. doi: 10.1016/j.plaphy.2019.02.009. [PMID: 30784987]
  • Ramit Singla, Navdeep Singla, Vikas Jaitak. Stevia rebaudiana targeting α-amylase: An in-vitro and in-silico mechanistic study. Natural product research. 2019 Feb; 33(4):548-552. doi: 10.1080/14786419.2017.1395433. [PMID: 29072099]
  • Erik N Gomes, Diego Moterle, Luiz Antonio Biasi, Henrique S Koehler, Luiz Alberto Kanis, Cícero Deschamps. Plant densities and harvesting times on productive and physiological aspects of Stevia rebaudiana Bertoni grown in southern Brazil. Anais da Academia Brasileira de Ciencias. 2018 Oct; 90(4):3249-3264. doi: 10.1590/0001-3765201820170510. [PMID: 30517213]
  • Liangliang Chen, Ping Sun, Fangfang Zhou, Yan Li, Kequan Chen, Honghua Jia, Ming Yan, Dachun Gong, Pingkai Ouyang. Synthesis of rebaudioside D, using glycosyltransferase UGTSL2 and in situ UDP-glucose regeneration. Food chemistry. 2018 Sep; 259(?):286-291. doi: 10.1016/j.foodchem.2018.03.126. [PMID: 29680056]
  • Mousumi Debnath, Nanjappa Ashwath, Camilla Beate Hill, Damien L Callahan, Daniel Anthony Dias, Nirupama Samanmalie Jayasinghe, David James Midmore, Ute Roessner. Comparative metabolic and ionomic profiling of two cultivars of Stevia rebaudiana Bert. (Bertoni) grown under salinity stress. Plant physiology and biochemistry : PPB. 2018 Aug; 129(?):56-70. doi: 10.1016/j.plaphy.2018.05.001. [PMID: 29800808]
  • Yuxin Wang, Linyao Li, Yawen Wang, Xiaokang Zhu, Mingdong Jiang, Erqun Song, Yang Song. New application of the commercial sweetener rebaudioside a as a hepatoprotective candidate: Induction of the Nrf2 signaling pathway. European journal of pharmacology. 2018 Mar; 822(?):128-137. doi: 10.1016/j.ejphar.2018.01.020. [PMID: 29355553]
  • Jingle Jiang, Lina Qi, Quanwei Wei, Fangxiong Shi. Effects of daily exposure to saccharin sodium and rebaudioside A on the ovarian cycle and steroidogenesis in rats. Reproductive toxicology (Elmsford, N.Y.). 2018 03; 76(?):35-45. doi: 10.1016/j.reprotox.2017.12.006. [PMID: 29262312]
  • Fatemeh Esmaeili, Matin Ghaheri, Danial Kahrizi, Mohsen Mansouri, Seyed Mehdi Safavi, Tayebeh Ghorbani, Sarre Muhammadi, Elham Rahmanian, Siavash Vaziri. Effects of various glutamine concentrations on gene expression and steviol glycosides accumulation in Stevia rebaudiana Bertoni. Cellular and molecular biology (Noisy-le-Grand, France). 2018 Feb; 64(2):1-5. doi: 10.14715/cmb/2018.64.2.1. [PMID: 29433620]
  • Matin Ghaheri, Elaheh Adibrad, Seyed Mehdi Safavi, Danial Kahrizi, Ali Soroush, Saare Muhammadi, Tayebeh Ghorbani, Ali Sabzevari, Zahra Ansarypour, Elham Rahmanian. Effects of life cycle and leaves location on gene expression and glycoside biosynthesis pathway in Stevia rebaudiana Bertoni. Cellular and molecular biology (Noisy-le-Grand, France). 2018 Feb; 64(2):17-22. doi: 10.14715/cmb/2018.64.2.4. [PMID: 29433623]
  • Danial Kahrizi, Matin Ghaheri, Zahra Yari, Khirollah Yari, Sohbat Bahraminejad. Investigation of different concentrations of MS media effects on gene expression and steviol glycosides accumulation in Stevia rebaudiana Bertoni. Cellular and molecular biology (Noisy-le-Grand, France). 2018 02; 64(2):23-27. doi: 10.14715/cmb/2018.64.2.11. [PMID: 29433624]
  • Fariba Akbari, Ali Arminian, Danial Kahrizi, Arash Fazeli, Matin Ghaheri. Effect of nitrogen sources on gene expression of Stevia rebaudiana (Bertoni) under in vitro conditions. Cellular and molecular biology (Noisy-le-Grand, France). 2018 Feb; 64(2):11-16. doi: 10.14715/cmb/2018.64.2.3. [PMID: 29433622]
  • Alireza Mirzaei, Gholamreza Kavoosi, Sara Dezhsetan, Mahdi Behnamian. Metal oxides as a biostimulator for upregulation of genes involved in the biosynthesis of Rebaudioside- A. Cellular and molecular biology (Noisy-le-Grand, France). 2018 Feb; 64(2):32-38. doi: 10.14715/cmb/2018.64.2.7. [PMID: 29433626]
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