Oleoylethanolamide (BioDeep_00000015031)
Main id: BioDeep_00000018228
PANOMIX_OTCML-2023
代谢物信息卡片
N-Oleoylethanolamine
化学式: C20H39NO2 (325.2980634)
中文名称: 油酰单乙醇胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCC/C=C\CCCCCCCC(=O)NCCO
InChI: InChI=1S/C20H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h9-10,22H,2-8,11-19H2,1H3,(H,21,23)/b10-9-
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D063385 - Cannabinoid Receptor Modulators
D018377 - Neurotransmitter Agents > D063385 - Cannabinoid Receptor Modulators > D063386 - Cannabinoid Receptor Agonists
COVID info from DrugBank
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
CONFIDENCE standard compound; INTERNAL_ID 31
Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.
Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.
同义名列表
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:71466
- KEGG: C20792
- KEGGdrug: D82195
- PubChem: 5283454
- ChEMBL: CHEMBL280065
- CAS: 111-58-0
- MoNA: RP003103
- MoNA: RP003102
- MoNA: RP003101
- PubChem: 254741259
- PDB-CCD: 5YM
- medchemexpress: HY-107542
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
6 个相关的物种来源信息
- 7227 Drosophila melanogaster: 10.1038/S41467-019-11933-Z
- 3039 Euglena gracilis: 10.3389/FBIOE.2021.662655
- 7461 Apis cerana: 10.1371/JOURNAL.PONE.0175573
- 7227 Drosophila melanogaster: 10.1038/S41467-019-11933-Z
- 3039 Euglena gracilis: 10.3389/FBIOE.2021.662655
- 7461 Apis cerana: 10.1371/JOURNAL.PONE.0175573
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Xianru Xia, Xiandong Li, Fei Xie, Guolin Yuan, Dongliang Cheng, Chunyan Peng. Non-targeted metabonomic analysis of plasma in patients with atherosclerosis by liquid chromatography-mass spectrometry.
Annals of translational medicine.
2022 Feb; 10(3):133. doi:
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Toxicology in vitro : an international journal published in association with BIBRA.
2022 Feb; 78(?):105268. doi:
10.1016/j.tiv.2021.105268. [PMID: 34756920] - Claudia Manca, Stefano Pintus, Elisabetta Murru, Giovanni Fantola, Michela Vincis, Barbara Batetta, Enrico Moroni, Gianfranca Carta, Sebastiano Banni. Fatty Acid Metabolism and Derived-Mediators Distinctive of PPAR-α Activation in Obese Subjects Post Bariatric Surgery.
Nutrients.
2021 Dec; 13(12):. doi:
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American journal of physiology. Endocrinology and metabolism.
2020 09; 319(3):E647-E657. doi:
10.1152/ajpendo.00146.2020. [PMID: 32776827] - Chelsea R Hutch, Danielle R Trakimas, Karen Roelofs, Joshua Pressler, Joyce Sorrell, Daniela Cota, Silvana Obici, Darleen A Sandoval. Oea Signaling Pathways and the Metabolic Benefits of Vertical Sleeve Gastrectomy.
Annals of surgery.
2020 03; 271(3):509-518. doi:
10.1097/sla.0000000000003093. [PMID: 30702457] - P Bachkangi, A H Taylor, Monica Bari, Mauro Maccarrone, Justin C Konje. Prediction of preterm labour from a single blood test: The role of the endocannabinoid system in predicting preterm birth in high-risk women.
European journal of obstetrics, gynecology, and reproductive biology.
2019 Dec; 243(?):1-6. doi:
10.1016/j.ejogrb.2019.09.029. [PMID: 31618675] - Yuanying Fang, Jun Xu, Zhifeng Li, Zunhua Yang, Lijuan Xiong, Yi Jin, Qi Wang, Saisai Xie, Wufu Zhu, Sheng Chang. Design and synthesis of novel pyrimido[5,4-d]pyrimidine derivatives as GPR119 agonist for treatment of type 2 diabetes.
Bioorganic & medicinal chemistry.
2018 08; 26(14):4080-4087. doi:
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Scandinavian journal of gastroenterology.
2017 Oct; 52(10):1133-1139. doi:
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2015 Sep; 10(3):396-401. doi:
10.1007/s11481-015-9624-y. [PMID: 26232265] - Fabrizio Montecucco, Sébastien Lenglet, Alessandra Quercioli, Fabienne Burger, Aurélien Thomas, Estelle Lauer, Analina Raquel da Silva, François Mach, Nicolas Vuilleumier, Elisabetta Bobbioni-Harsch, Alain Golay, Thomas H Schindler, Zoltan Pataky. Gastric bypass in morbid obese patients is associated with reduction in adipose tissue inflammation via N-oleoylethanolamide (OEA)-mediated pathways.
Thrombosis and haemostasis.
2015 Apr; 113(4):838-50. doi:
10.1160/th14-06-0506. [PMID: 25413674] - Miguel Wulff-Pérez, Francisco J Pavón, Antonio Martín-Rodríguez, Juan de Vicente, Francisco Alen, Fernando Rodríguez de Fonseca, María J Gálvez-Ruiz, Antonia Serrano. Preparation, characterization and in vivo evaluation of nanoemulsions for the controlled delivery of the antiobesity agent N-oleoylethanolamine.
Nanomedicine (London, England).
2014 Dec; 9(18):2761-72. doi:
10.2217/nnm.14.35. [PMID: 24673263] - Wenjing Li, Xiaoyan Yang, Shasha Xing, Fang Bian, Wanjing Yao, Xiangli Bai, Tao Zheng, Guangjie Wu, Si Jin. Endogenous ceramide contributes to the transcytosis of oxLDL across endothelial cells and promotes its subendothelial retention in vascular wall.
Oxidative medicine and cellular longevity.
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Science (New York, N.Y.).
2013 Aug; 341(6147):800-2. doi:
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Journal of medicinal chemistry.
2013 May; 56(9):3518-30. doi:
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American journal of physiology. Endocrinology and metabolism.
2012 Dec; 303(12):E1469-78. doi:
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Current cancer drug targets.
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Psychoneuroendocrinology.
2012 Jun; 37(6):844-51. doi:
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The Journal of pharmacology and experimental therapeutics.
2011 Feb; 336(2):423-30. doi:
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PloS one.
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Bioanalysis.
2011 Jan; 3(2):181-96. doi:
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Liver international : official journal of the International Association for the Study of the Liver.
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Molecular endocrinology (Baltimore, Md.).
2010 Jan; 24(1):161-70. doi:
10.1210/me.2009-0239. [PMID: 19901198] - O I Voĭtychuk, V S Asmolkova, N M Hula, M Oz, Ia M Shuba. [Effects of N-stearoyl- and N-oleoylethanolamine on cardiac voltage-dependent sodium channels].
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2010; 56(5):13-22. doi:
10.15407/fz56.05.013. [PMID: 21265075] - María Martínez de Ubago, Inmaculada García-Oya, Antonio Pérez-Pérez, Alberto Canfrán-Duque, Rocio Quintana-Portillo, Fernando Rodríguez de Fonseca, Carmen González-Yanes, Víctor Sánchez-Margalet. Oleoylethanolamide, a natural ligand for PPAR-alpha, inhibits insulin receptor signalling in HTC rat hepatoma cells.
Biochimica et biophysica acta.
2009 Aug; 1791(8):740-5. doi:
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The Journal of endocrinology.
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2008 Jan; 17(1):1-10. doi:
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Cell metabolism.
2006 Mar; 3(3):167-75. doi:
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American journal of physiology. Regulatory, integrative and comparative physiology.
2005 Sep; 289(3):R729-37. doi:
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Neuropharmacology.
2005 Jun; 48(8):1147-53. doi:
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