Benzil (BioDeep_00000013307)

 

Secondary id: BioDeep_00001868193

human metabolite blood metabolite Industrial Pollutants Volatile Flavor Compounds


代谢物信息卡片


1,2-Diphenylethane-1,2-dione

化学式: C14H10O2 (210.06807600000002)
中文名称: 苯偶酰, 1,2-二苯基-1,2-乙二酮
谱图信息: 最多检出来源 Homo sapiens(blood) 10.42%

分子结构信息

SMILES: C1=CC=C(C=C1)C(=O)C(=O)C2=CC=CC=C2
InChI: InChI=1S/C14H10O2/c15-13(11-7-3-1-4-8-11)14(16)12-9-5-2-6-10-12/h1-10H

描述信息

同义名列表

9 个代谢物同义名

1,2-Diphenylethane-1,2-dione; Diphenyl-alpha-beta-ketone; Diphenylethane-1,2-dione; Diphenylethanedione; Diphenylglyoxal; Bibenzoyl; BENZIL; Benzil; Benzil



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • M Jason Hatfield, Lyudmila G Tsurkan, Janice L Hyatt, Carol C Edwards, Andrew Lemoff, Cynthia Jeffries, Bing Yan, Philip M Potter. Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza ('Danshen'). Journal of natural products. 2013 Jan; 76(1):36-44. doi: 10.1021/np300628a. [PMID: 23286284]
  • Chi C Wong, Ka-Wing Cheng, Gang Xie, Dingying Zhou, Cai-Hua Zhu, Panayiotis P Constantinides, Basil Rigas. Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity. The Journal of pharmacology and experimental therapeutics. 2012 Feb; 340(2):422-32. doi: 10.1124/jpet.111.188508. [PMID: 22085648]
  • Stefan Safer, Serhat S Cicek, Valerio Pieri, Stefan Schwaiger, Peter Schneider, Volker Wissemann, Hermann Stuppner. Metabolic fingerprinting of Leontopodium species (Asteraceae) by means of ¹H NMR and HPLC-ESI-MS. Phytochemistry. 2011 Aug; 72(11-12):1379-89. doi: 10.1016/j.phytochem.2011.04.006. [PMID: 21550615]
  • Thommey P Thomas, Baohua Huang, Ankur Desai, Hong Zong, Xue-Min Cheng, Alina Kotlyar, Pascale R Leroueil, Thomas Dunham, Abraham van der Spek, Brent B Ward, James R Baker. Plasma-mediated release of morphine from synthesized prodrugs. Bioorganic & medicinal chemistry letters. 2010 Nov; 20(21):6250-3. doi: 10.1016/j.bmcl.2010.08.098. [PMID: 20833544]
  • T Sreelatha, A Hymavathi, V Rama Subba Rao, P Devanand, P Usha Rani, J Madhusudana Rao, K Suresh Babu. A new benzil derivative from Derris scandens: Structure-insecticidal activity study. Bioorganic & medicinal chemistry letters. 2010 Jan; 20(2):549-53. doi: 10.1016/j.bmcl.2009.11.103. [PMID: 19969457]
  • Ting Gong, Dong-Xiao Wang, Ruo-Yun Chen, Ping Liu, De-Quan Yu. Novel benzil and isoflavone derivatives from Millettia dielsiana. Planta medica. 2009 Feb; 75(3):236-42. doi: 10.1055/s-0028-1112203. [PMID: 19140097]
  • Toshiyuki Harada, Yoshiaki Nakagawa, Randy M Wadkins, Philip M Potter, Craig E Wheelock. Comparison of benzil and trifluoromethyl ketone (TFK)-mediated carboxylesterase inhibition using classical and 3D-quantitative structure-activity relationship analysis. Bioorganic & medicinal chemistry. 2009 Jan; 17(1):149-64. doi: 10.1016/j.bmc.2008.11.008. [PMID: 19062296]
  • Seru Ganapaty, Guttula Veera Kantha Srilakshmi, Steve Thomas Pannakal, Hafizur Rahman, Hartmut Laatsch, Reto Brun. Cytotoxic benzil and coumestan derivatives from Tephrosia calophylla. Phytochemistry. 2009 Jan; 70(1):95-9. doi: 10.1016/j.phytochem.2008.10.009. [PMID: 19062050]
  • Muhammad Iqbal Choudhary, Sumaira Hareem, Hina Siddiqui, Shazia Anjum, Shamsher Ali, Atta-Ur-Rahman, Mudassir Israr Zaidi. A benzil and isoflavone from Iris tenuifolia. Phytochemistry. 2008 Jun; 69(9):1880-5. doi: 10.1016/j.phytochem.2008.03.011. [PMID: 18472117]
  • YuanYuan Zhang, XiaoHui Chen, ShengYing Qin, ChulSa Kim, Shin-ichi Tebayashi, KaiShun Bi. LC-MS method for determination and pharmacokinetic study of chimaphilin in rat plasma after oral administration of the traditional Chinese medicinal preparation Lu xian cao decoction. Biological & pharmaceutical bulletin. 2006 Dec; 29(12):2523-7. doi: 10.1248/bpb.29.2523. [PMID: 17142995]
  • W Mahabusarakam, S Deachathai, S Phongpaichit, C Jansakul, W C Taylor. A benzil and isoflavone derivatives from Derris scandens Benth. Phytochemistry. 2004 Apr; 65(8):1185-91. doi: 10.1016/j.phytochem.2004.03.006. [PMID: 15110702]
  • Asiye Meriç, Zerrin Incesu, Ilhan Işikdağ. Synthesis and effects on intracellular calcium of some 1,3-bis-(heteroaryl substituted)benzene derivatives. Farmaco (Societa chimica italiana : 1989). 2002 Jul; 57(7):543-8. doi: 10.1016/s0014-827x(02)01246-6. [PMID: 12164210]
  • S Fujisawa, Y Kadoma, E Masuhara. Effects of photoinitiators for the visible-light resin system on hemolysis of dog erythrocytes and lipid peroxidation of their components. Journal of dental research. 1986 Sep; 65(9):1186-90. doi: 10.1177/00220345860650091401. [PMID: 3461034]
  • K Osterlind, M Hansen, H H Hansen, P Dombernowsky. Controlled trial of RSV, herbs or placebo as adjuvants to complete resection of squamous cell lung cancer. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 1985 Dec; 11(4):349-51. doi: ". [PMID: 3905440]
  • Y Uehara, M Hori, T Takeuchi, H Umezawa. Screening of agents which convert 'transformed morphology' of Rous sarcoma virus-infected rat kidney cells to 'normal morphology': identification of an active agent as herbimycin and its inhibition of intracellular src kinase. Japanese journal of cancer research : Gann. 1985 Aug; 76(8):672-5. doi: . [PMID: 3930444]