L-Olivosyl-oleandolide (BioDeep_00000009020)
natural product Cytotoxicity
代谢物信息卡片
化学式: C26H44O10 (516.2934324)
中文名称: 橄榄酸基-去氧olean烷醇
谱图信息:
最多检出来源 Homo sapiens(blood) 0.05%
Last reviewed on 2024-07-15.
Cite this Page
L-Olivosyl-oleandolide. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/l-olivosyl-oleandolide (retrieved
2024-11-24) (BioDeep RN: BioDeep_00000009020). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
分子结构信息
SMILES: CC1CC2(CO2)C(=O)C(C(C(C(OC(=O)C(C(C(C1O)C)OC3CC(C(C(O3)C)O)O)C)C)C)O)C
InChI: InChI=1S/C26H44O10/c1-11-9-26(10-33-26)24(31)14(4)21(29)12(2)16(6)35-25(32)15(5)23(13(3)20(11)28)36-19-8-18(27)22(30)17(7)34-19/h11-23,27-30H,8-10H2,1-7H3/t11-,12-,13+,14+,15+,16+,17-,18-,19-,20-,21-,22-,23-,26+/m0/s1
描述信息
3-O-(alpha-L-olivosyl)oleandolide is a macrolide that is oleandolide having a 2,6-dideoxy-alpha-L-arabino-hexopyranosyl (alpha-L-olivosyl) residue attached at position 3. It has a role as a metabolite. It is a macrolide, a glycoside and a monosaccharide derivative. It is functionally related to an oleandolide.
L-Olivosyl-oleandolide is a naturally occurring sesquiterpene lactone derivative that contains an olivosyl moiety, which is a specific type of ester derived from olivolic acid. The "L" in the name indicates that the olivosyl group is in the L-configuration, which refers to the spatial arrangement of atoms around the chiral center in the molecule. This compound is an example of a glycosylated sesquiterpene lactone, where the sesquiterpene lactone oleandolide is modified by the attachment of the olivosyl group.
The presence of the olivosyl group can alter the biological properties of the parent compound, oleandolide, potentially affecting its pharmacological activities such as cytotoxicity, anti-inflammatory effects, and antimicrobial activity. L-Olivosyl-oleandolide can be found in certain plant species and may contribute to the plant's defense mechanisms against pathogens and herbivores.
In its chemical structure, L-Olivosyl-oleandolide consists of a sesquiterpene lactone core with a lactone ring fused to a sesquiterpene framework, and it is appended with the L-olivosyl ester group, which adds complexity to its molecular structure and function. This compound is of interest in the fields of natural products chemistry and pharmacognosy for its potential therapeutic applications and as a subject of study for understanding the biosynthesis of such natural products.
同义名列表
1 个代谢物同义名
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:29614
- KEGG: C11991
- PubChem: 443565
- Metlin: METLIN40996
- LipidMAPS: LMPK04000032
- PMhub: MS000022757
- 3DMET: B04397
- NIKKAJI: J2.778.847E
- RefMet: L-Olivosyl-oleandolide
- LOTUS: LTS0214211
分类词条
相关代谢途径
Reactome(0)
PlantCyc(0)
代谢反应
1 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(1)
- oleandomycin biosynthesis:
(S)-methylmalonyl-CoA + H+ + NADPH + acetyl-CoA ⟶ 8,8a-deoxyoleandolide + CO2 + H2O + NADP+ + coenzyme A
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
8 个相关的物种来源信息
- 7458 - Apidae: LTS0214211
- 7459 - Apis: LTS0214211
- 7461 - Apis cerana: 10.1371/JOURNAL.PONE.0175573
- 7461 - Apis cerana: LTS0214211
- 6656 - Arthropoda: LTS0214211
- 2759 - Eukaryota: LTS0214211
- 50557 - Insecta: LTS0214211
- 33208 - Metazoa: LTS0214211
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- V V Vorontsov. [Effect of some phenothiazine derivatives on kidney function].
Farmakologiia i toksikologiia.
1975 May; 38(3):313-6. doi:
NULL
. [PMID: 6306]