alpha-thujone (BioDeep_00000899034)

   


代谢物信息卡片


alpha-thujone

化学式: C10H16O (152.12010859999998)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1C2CC2(CC1=O)C(C)C
InChI: InChI=1S/C10H16O/c1-6(2)10-4-8(10)7(3)9(11)5-10/h6-8H,4-5H2,1-3H3/t7-,8+,10+/m1/s1

描述信息

同义名列表

1 个代谢物同义名

alpha-thujone



数据库引用编号

1 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

13 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • R Sasidharan, L Brokate, E J Eilers, C Müller. Chemodiversity in flowers of Tanacetum vulgare has consequences on a florivorous beetle. Plant biology (Stuttgart, Germany). 2023 Dec; 25(7):1071-1082. doi: 10.1111/plb.13576. [PMID: 37703504]
  • Reza Zeynali, Sharareh Najafian, Mehdi Hosseinifarahi. Exogenous putrescine changes biochemical (antioxidant activity, polyphenol, flavonoid, and total phenol compounds) and essential oil constituents of Salvia officinalis L. Chemistry & biodiversity. 2023 Sep; ?(?):e202301043. doi: 10.1002/cbdv.202301043. [PMID: 37751472]
  • Abdellatif Alami, Abdelhakim El Ouali Lalami, Saoussan Annemer, Fouad El-Akhal, Yassine Ez Zoubi, Abdellah Farah. Chemical Composition and Larvicidal Properties of Essential Oils from Wild and Cultivated Artemisia campestris L., an Endemic Plant in Morocco. TheScientificWorldJournal. 2023; 2023(?):5748133. doi: 10.1155/2023/5748133. [PMID: 37849964]
  • Noura S Dosoky, William N Setzer. Maternal Reproductive Toxicity of Some Essential Oils and Their Constituents. International journal of molecular sciences. 2021 Feb; 22(5):. doi: 10.3390/ijms22052380. [PMID: 33673548]
  • Liping Bai, Wenjia Wang, Juan Hua, Zhifu Guo, Shihong Luo. Defensive functions of volatile organic compounds and essential oils from northern white-cedar in China. BMC plant biology. 2020 Nov; 20(1):500. doi: 10.1186/s12870-020-02716-6. [PMID: 33143644]
  • Carolina E Galvez, Cristina M Jimenez, Analía de Los A Gomez, Emilio F Lizarraga, Diego A Sampietro. Chemical composition and antifungal activity of essential oils from Senecio nutans, Senecio viridis, Tagetes terniflora and Aloysia gratissima against toxigenic Aspergillus and Fusarium species. Natural product research. 2020 May; 34(10):1442-1445. doi: 10.1080/14786419.2018.1511555. [PMID: 30456990]
  • Ramalingam Srinivasan, Arumugam Aruna, Jong Suk Lee, Myunghee Kim, Muthugounder Subramaniam Shivakumar, Devarajan Natarajan. Antioxidant and Antiproliferative Potential of Bioactive Molecules Ursolic Acid and Thujone Isolated from Memecylon edule and Elaeagnus indica and Their Inhibitory Effect on Topoisomerase II by Molecular Docking Approach. BioMed research international. 2020; 2020(?):8716927. doi: 10.1155/2020/8716927. [PMID: 32149143]
  • Mehran Mojarrad, Siavash Hosseini Sarghein, Ali Sonboli. Chemical diversity of the essential oils of twenty populations of Tanacetum polycephalum Sch. Bip. from Iran. Natural product research. 2019 May; 33(9):1379-1382. doi: 10.1080/14786419.2018.1474468. [PMID: 29768020]
  • Renato T F Paranaiba, Carlos B V Carvalho, Jorge M Freitas, Levy H Fassio, Élvio D Botelho, Diana B J Neves, Ronaldo C Silva, Sérgio M Aguiar. Forensic botany and forensic chemistry working together: application of plant DNA barcoding as a complement to forensic chemistry-a case study in Brazil. Genome. 2019 Jan; 62(1):11-18. doi: 10.1139/gen-2018-0066. [PMID: 30707055]
  • Irene Thamm, Konrad Tiefenbacher, Michael Rychlik. Quantification of α-Thujone and Its Metabolites in Human Urine after Consumption of a Sage Infusion Using Stable Isotope Dilution Assays. Toxins. 2018 12; 10(12):. doi: 10.3390/toxins10120511. [PMID: 30513900]
  • Hua Shao, Yunxia Hu, Caixia Han, Caixia Wei, Shixing Zhou, Chenpeng Zhang, Chi Zhang. Chemical Composition and Phytotoxic Activity of Seriphidium terrae-albae (Krasch.) Poljakov (Compositae) Essential Oil. Chemistry & biodiversity. 2018 Nov; 15(11):e1800348. doi: 10.1002/cbdv.201800348. [PMID: 30168654]
  • Chiara Di Lorenzo, Francesco Ferretti, Enzo Moro, Alessandro Ceschi, Francesca Colombo, Gianfranco Frigerio, Saskia Lüde, Patrizia Restani. Identification and Quantification of Thujone in a Case of Poisoning Due to Repeated Ingestion of an Infusion of Artemisia Vulgaris L. Journal of food science. 2018 Aug; 83(8):2257-2264. doi: 10.1111/1750-3841.14273. [PMID: 30044501]
  • Faten Younsi, Najoua Rahali, Sameh Mehdi, Mohamed Boussaid, Chokri Messaoud. Relationship between chemotypic and genetic diversity of natural populations of Artemisia herba-alba Asso growing wild in Tunisia. Phytochemistry. 2018 Apr; 148(?):48-56. doi: 10.1016/j.phytochem.2018.01.014. [PMID: 29421510]
  • Niluni M Wijesundara, H P Vasantha Rupasinghe. Essential oils from Origanum vulgare and Salvia officinalis exhibit antibacterial and anti-biofilm activities against Streptococcus pyogenes. Microbial pathogenesis. 2018 Apr; 117(?):118-127. doi: 10.1016/j.micpath.2018.02.026. [PMID: 29452197]
  • Sanpeng Fan, Jin Chang, Yufeng Zong, Gaosheng Hu, Jingming Jia. GC-MS Analysis of the Composition of the Essential Oil from Dendranthema indicum Var. Aromaticum Using Three Extraction Methods and Two Columns. Molecules (Basel, Switzerland). 2018 Mar; 23(3):. doi: 10.3390/molecules23030576. [PMID: 29510531]
  • Eirini Sarrou, Ioannis Ganopoulos, Aliki Xanthopoulou, Domenico Masuero, Stefan Martens, Panagiotis Madesis, Athanasios Mavromatis, Paschalina Chatzopoulou. Genetic diversity and metabolic profile of Salvia officinalis populations: implications for advanced breeding strategies. Planta. 2017 Aug; 246(2):201-215. doi: 10.1007/s00425-017-2666-z. [PMID: 28314999]
  • Benoit Bach, Marilyn Cleroux, Mayra Saillen, Patrik Schönenberger, Stephane Burgos, Julien Ducruet, Armelle Vallat. A new chemical tool for absinthe producers, quantification of α/β-thujone and the bitter components in Artemisia absinthium. Food chemistry. 2016 Dec; 213(?):813-817. doi: 10.1016/j.foodchem.2016.06.045. [PMID: 27451252]
  • Asta Judzentiene, Rasa Garjonyte. Compositional Variability and Toxic Activity of Mugwort (Artemisia vulgaris) Essential Oils. Natural product communications. 2016 Sep; 11(9):1353-1356. doi: . [PMID: 30807041]
  • Alessandra Manzo, Loana Musso, Sara Panseri, Marcello Iriti, Sabrina Dallavalle, Enrico Catalano, Giorgio Scarì, Annamaria Giorgi. Screening of the chemical composition and bioactivity of Waldheimia glabra (Decne.) Regel essential oil. Journal of the science of food and agriculture. 2016 Jul; 96(9):3195-201. doi: 10.1002/jsfa.7499. [PMID: 26467601]
  • Jack D Williams, Jessica A Yazarians, Chelcie C Almeyda, Kristin A Anderson, Gregory R Boyce. Detection of the Previously Unobserved Stereoisomers of Thujone in the Essential Oil and Consumable Products of Sage (Salvia officinalis L.) Using Headspace Solid-Phase Microextraction-Gas Chromatography-Mass Spectrometry. Journal of agricultural and food chemistry. 2016 Jun; 64(21):4319-26. doi: 10.1021/acs.jafc.6b01065. [PMID: 27181395]
  • Angelo Torres, Yosselyn Vargas, Daniel Uribe, Cristian Carrasco, Cristian Torres, René Rocha, Carlos Oyarzún, Rody San Martín, Claudia Quezada. Pro-apoptotic and anti-angiogenic properties of the α /β-thujone fraction from Thuja occidentalis on glioblastoma cells. Journal of neuro-oncology. 2016 05; 128(1):9-19. doi: 10.1007/s11060-016-2076-2. [PMID: 26900077]
  • Michal P Dybowski, Andrzej L Dawidowicz. The determination of α- and β-thujone in human serum - Simple analysis of absinthe congener substance. Forensic science international. 2016 Feb; 259(?):188-92. doi: 10.1016/j.forsciint.2015.12.015. [PMID: 26773227]
  • Rosaria Cozzolino, Sadrollah Ramezani, Antonella Martignetti, Angela Mari, Sonia Piacente, Beatrice De Giulio. Determination of volatile organic compounds in the dried leaves of Salvia species by solid-phase microextraction coupled to gas chromatography mass spectrometry. Natural product research. 2016; 30(7):841-8. doi: 10.1080/14786419.2015.1076817. [PMID: 26305878]
  • Esra Küpeli Akkol, Mert İlhan, Mürşide Ayşe Demirel, Hikmet Keleş, Ibrahim Tümen, İpek Süntar. Thuja occidentalis L. and its active compound, α-thujone: Promising effects in the treatment of polycystic ovary syndrome without inducing osteoporosis. Journal of ethnopharmacology. 2015 Jun; 168(?):25-30. doi: 10.1016/j.jep.2015.03.029. [PMID: 25818694]
  • M Mahboubi, N Kazempour. The antifungal activity of Artemisia sieberi essential oil from different localities of Iran against dermatophyte fungi. Journal de mycologie medicale. 2015 Jun; 25(2):e65-71. doi: 10.1016/j.mycmed.2015.02.042. [PMID: 25770648]
  • Andreas Gesell, Markus Blaukopf, Lina Madilao, Macaire M S Yuen, Stephen G Withers, Jim Mattsson, John H Russell, Jörg Bohlmann. The gymnosperm cytochrome P450 CYP750B1 catalyzes stereospecific monoterpene hydroxylation of (+)-sabinene in thujone biosynthesis in western redcedar. Plant physiology. 2015 May; 168(1):94-106. doi: 10.1104/pp.15.00315. [PMID: 25829465]
  • Cory Creed, Ariel Mollhagen, Noelle Mollhagen, Maciej A Pszczolkowski. Artemisia arborescens 'Powis Castle' extracts and α-thujone prevent fruit infestation by codling moth neonates. Pharmaceutical biology. 2015; 53(10):1458-64. doi: 10.3109/13880209.2014.985796. [PMID: 25853962]
  • Richard Karban, William C Wetzel, Kaori Shiojiri, Satomi Ishizaki, Santiago R Ramirez, James D Blande. Deciphering the language of plant communication: volatile chemotypes of sagebrush. The New phytologist. 2014 Oct; 204(2):380-5. doi: 10.1111/nph.12887. [PMID: 24920243]
  • Haobin Hu, Xudong Zheng, Huaisheng Hu, Ruirui Wang, Yun Wu. Study on gas chromatography-mass spectrometry fingerprint of Acanthopanax brachypus. Journal of chromatographic science. 2014 Sep; 52(8):759-65. doi: 10.1093/chromsci/bmt137. [PMID: 24076562]
  • Effie Hanlidou, Regina Karousou, Diamanto Lazari. Essential-oil diversity of Salvia tomentosa Mill. in Greece. Chemistry & biodiversity. 2014 Aug; 11(8):1205-15. doi: 10.1002/cbdv.201300408. [PMID: 25146764]
  • Lucia D'Ulivo. The absinthe challenge. Analytical and bioanalytical chemistry. 2014 Mar; 406(7):1815-6. doi: 10.1007/s00216-013-7576-8. [PMID: 24632744]
  • Alessandro Venditti, Filippo Maggi, Sauro Vittori, Fabrizio Papa, Anna Maria Serrilli, Mirella Di Cecco, Giampiero Ciaschetti, Manuela Mandrone, Ferruccio Poli, Armandodoriano Bianco. Volatile compounds from Achillea tenorii (Grande) growing in the Majella National Park (Italy). Natural product research. 2014; 28(20):1699-704. doi: 10.1080/14786419.2014.940349. [PMID: 25103502]
  • Sandra Kleine, Caroline Müller. Differences in shoot and root terpenoid profiles and plant responses to fertilisation in Tanacetum vulgare. Phytochemistry. 2013 Dec; 96(?):123-31. doi: 10.1016/j.phytochem.2013.09.018. [PMID: 24128753]
  • Györgyi Horváth, Kamilla Acs, Béla Kocsis. TLC-direct bioautography for determination of antibacterial activity of Artemisia adamsii essential oil. Journal of AOAC International. 2013 Nov; 96(6):1209-13. doi: 10.5740/jaoacint.sgehorvath. [PMID: 24645495]
  • Suramya Waidyanatha, Jerry D Johnson, S Peter Hong, Veronica Godfrey Robinson, Seth Gibbs, Steven W Graves, Michelle J Hooth, Cynthia S Smith. Toxicokinetics of α-thujone following intravenous and gavage administration of α-thujone or α- and β-thujone mixture in male and female F344/N rats and B6C3F1 mice. Toxicology and applied pharmacology. 2013 Sep; 271(2):216-28. doi: 10.1016/j.taap.2013.05.001. [PMID: 23669748]
  • Agnieszka Arceusz, Andrea Occhipinti, Andrea Capuzzo, Massimo E Maffei. Comparison of different extraction methods for the determination of α- and β-thujone in sage (Salvia officinalis L.) herbal tea. Journal of separation science. 2013 Sep; 36(18):3130-4. doi: 10.1002/jssc.201300206. [PMID: 23843295]
  • Miriam M Ehrnhöfer-Ressler, Kristina Fricke, Marc Pignitter, Joel M Walker, Jessica Walker, Michael Rychlik, Veronika Somoza. Identification of 1,8-cineole, borneol, camphor, and thujone as anti-inflammatory compounds in a Salvia officinalis L. infusion using human gingival fibroblasts. Journal of agricultural and food chemistry. 2013 Apr; 61(14):3451-9. doi: 10.1021/jf305472t. [PMID: 23488631]
  • Adam J Foster, Dawn E Hall, Leanne Mortimer, Shelley Abercromby, Regine Gries, Gerhard Gries, Jörg Bohlmann, John Russell, Jim Mattsson. Identification of genes in Thuja plicata foliar terpenoid defenses. Plant physiology. 2013 Apr; 161(4):1993-2004. doi: 10.1104/pp.112.206383. [PMID: 23388118]
  • Olavi Pelkonen, Khaled Abass, Jacqueline Wiesner. Thujone and thujone-containing herbal medicinal and botanical products: toxicological assessment. Regulatory toxicology and pharmacology : RTP. 2013 Feb; 65(1):100-7. doi: 10.1016/j.yrtph.2012.11.002. [PMID: 23201408]
  • S Bouajaj, A Benyamna, H Bouamama, A Romane, D Falconieri, A Piras, B Marongiu. Antibacterial, allelopathic and antioxidant activities of essential oil of Salvia officinalis L. growing wild in the Atlas Mountains of Morocco. Natural product research. 2013; 27(18):1673-6. doi: 10.1080/14786419.2012.751600. [PMID: 23240623]
  • Sabine Grausgruber-Gröger, Corinna Schmiderer, Ralf Steinborn, Johannes Novak. Seasonal influence on gene expression of monoterpene synthases in Salvia officinalis (Lamiaceae). Journal of plant physiology. 2012 Mar; 169(4):353-9. doi: 10.1016/j.jplph.2011.11.004. [PMID: 22196947]
  • Biljana Nikolić, Dragana Mitić-Ćulafić, Branka Vuković-Gačić, Jelena Knežević-Vukčević. Modulation of genotoxicity and DNA repair by plant monoterpenes camphor, eucalyptol and thujone in Escherichia coli and mammalian cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2011 Sep; 49(9):2035-45. doi: 10.1016/j.fct.2011.05.015. [PMID: 21620923]
  • Nour W Al-Haj Baddar, Talal A Aburjai, Mutasem O Taha, Ahmad M Disi. Thujone corrects cholesterol and triglyceride profiles in diabetic rat model. Natural product research. 2011 Jul; 25(12):1180-4. doi: 10.1080/14786419.2010.496116. [PMID: 21740283]
  • Hédi Mighri, Ahmed Akrout, Hajer El-jeni, Slah Zaidi, Félix Tomi, Joseph Casanova, Mohamed Neffati. Composition and intraspecific chemical variability of the essential oil from Artemisia herba-alba growing wild in a Tunisian arid zone. Chemistry & biodiversity. 2010 Nov; 7(11):2709-17. doi: 10.1002/cbdv.201000054. [PMID: 21072770]
  • Ilioara Oniga, R Oprean, Anca Toiu, Daniela Benedec. Chemical composition of the essential oil of Salvia officinalis L. from Romania. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi. 2010 Apr; 114(2):593-5. doi: . [PMID: 20701010]
  • A Laciar, M L Vaca Ruiz, R Carrizo Flores, J R Saad. Antibacterial and antioxidant activities of the essential oil of Artemisia echegarayi Hieron. (Asteraceae). Revista Argentina de microbiologia. 2009 Oct; 41(4):226-31. doi: ". [PMID: 20085186]
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