Glyoxylate (BioDeep_00000897518)

   


代谢物信息卡片


Glyoxylate

化学式: C2HO3- (72.9925696)
中文名称: 乙醛酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(=O)C(=O)[O-]
InChI: InChI=1S/C2H2O3/c3-1-2(4)5/h1H,(H,4,5)/p-1

描述信息

The conjugate base of glyoxylic acid.

同义名列表

1 个代谢物同义名

Glyoxylate



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(32)

PlantCyc(7)

代谢反应

326 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(42)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(284)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Ruth Belostotsky, Yaacov Frishberg. Catabolism of Hydroxyproline in Vertebrates: Physiology, Evolution, Genetic Diseases and New siRNA Approach for Treatment. International journal of molecular sciences. 2022 Jan; 23(2):. doi: 10.3390/ijms23021005. [PMID: 35055190]
  • Bohan Wang, Jingchao Wei, Qi Huangfu, Fei Gao, Lanxin Qin, Jiao Zhong, Jiaming Wen, Zhangqun Ye, Xiaoqi Yang, Haoran Liu. Identification of Resolvin D1 and Protectin D1 as Potential Therapeutic Agents for Treating Kidney Stones. Oxidative medicine and cellular longevity. 2022; 2022(?):4345037. doi: 10.1155/2022/4345037. [PMID: 35251472]
  • Shuo Zhao, Daniel Garcia, Yinglei Zhao, Danfeng Huang. Hydro-Electro Hybrid Priming Promotes Carrot (Daucus carota L.) Seed Germination by Activating Lipid Utilization and Respiratory Metabolism. International journal of molecular sciences. 2021 Oct; 22(20):. doi: 10.3390/ijms222011090. [PMID: 34681749]
  • Qing-Lin Ye, Da-Ming Wang, Xin Wang, Zhi-Qiang Zhang, Qi-Xing Tian, Shi-Yao Feng, Zhi-Hui Zhang, De-Xin Yu, De-Mao Ding, Dong-Dong Xie. Sirt1 inhibits kidney stones formation by attenuating calcium oxalate-induced cell injury. Chemico-biological interactions. 2021 Sep; 347(?):109605. doi: 10.1016/j.cbi.2021.109605. [PMID: 34333021]
  • Hiromasa Tanaka, Yugo Hosoi, Kenji Ishikawa, Jun Yoshitake, Takahiro Shibata, Koji Uchida, Hiroshi Hashizume, Masaaki Mizuno, Yasumasa Okazaki, Shinya Toyokuni, Kae Nakamura, Hiroaki Kajiyama, Fumitaka Kikkawa, Masaru Hori. Low temperature plasma irradiation products of sodium lactate solution that induce cell death on U251SP glioblastoma cells were identified. Scientific reports. 2021 09; 11(1):18488. doi: 10.1038/s41598-021-98020-w. [PMID: 34531507]
  • Kathrin Gianmoena, Nina Gasparoni, Adelina Jashari, Philipp Gabrys, Katharina Grgas, Ahmed Ghallab, Karl Nordström, Gilles Gasparoni, Jörg Reinders, Karolina Edlund, Patricio Godoy, Alexander Schriewer, Heiko Hayen, Christian A Hudert, Georg Damm, Daniel Seehofer, Thomas S Weiss, Peter Boor, Hans-Joachim Anders, Manga Motrapu, Peter Jansen, Tobias S Schiergens, Maren Falk-Paulsen, Philip Rosenstiel, Clivia Lisowski, Eduardo Salido, Rosemarie Marchan, Jörn Walter, Jan G Hengstler, Cristina Cadenas. Epigenomic and transcriptional profiling identifies impaired glyoxylate detoxification in NAFLD as a risk factor for hyperoxaluria. Cell reports. 2021 08; 36(8):109526. doi: 10.1016/j.celrep.2021.109526. [PMID: 34433051]
  • Hiba Baaziz, K Karl Compton, Sherry B Hildreth, Richard F Helm, Birgit E Scharf. McpT, a Broad-Range Carboxylate Chemoreceptor in Sinorhizobium meliloti. Journal of bacteriology. 2021 08; 203(17):e0021621. doi: 10.1128/jb.00216-21. [PMID: 34124939]
  • Tao Ding, Tingting Zhao, Yinhui Li, Zhixiao Liu, Jiarong Ding, Boyao Ji, Yue Wang, Zhiyong Guo. Vitexin exerts protective effects against calcium oxalate crystal-induced kidney pyroptosis in vivo and in vitro. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2021 Jun; 86(?):153562. doi: 10.1016/j.phymed.2021.153562. [PMID: 33857849]
  • Khushboo Borah, Tom A Mendum, Nathaniel D Hawkins, Jane L Ward, Michael H Beale, Gerald Larrouy-Maumus, Apoorva Bhatt, Martine Moulin, Michael Haertlein, Gernot Strohmeier, Harald Pichler, V Trevor Forsyth, Stephan Noack, Celia W Goulding, Johnjoe McFadden, Dany J V Beste. Metabolic fluxes for nutritional flexibility of Mycobacterium tuberculosis. Molecular systems biology. 2021 05; 17(5):e10280. doi: 10.15252/msb.202110280. [PMID: 33943004]
  • Long He, Peng Jin, Xuan Chen, Tian-Ye Zhang, Kai-Li Zhong, Peng Liu, Jian-Ping Chen, Jian Yang. Comparative proteomic analysis of Nicotiana benthamiana plants under Chinese wheat mosaic virus infection. BMC plant biology. 2021 Jan; 21(1):51. doi: 10.1186/s12870-021-02826-9. [PMID: 33468046]
  • Xi Jin, Zhongyu Jian, Xiaoting Chen, Yucheng Ma, Hongwen Ma, Yu Liu, Lina Gong, Liyuan Xiang, Shiyu Zhu, Xiaoling Shu, Shiqian Qi, Hong Li, Kunjie Wang. Short Chain Fatty Acids Prevent Glyoxylate-Induced Calcium Oxalate Stones by GPR43-Dependent Immunomodulatory Mechanism. Frontiers in immunology. 2021; 12(?):729382. doi: 10.3389/fimmu.2021.729382. [PMID: 34675921]
  • Mirco Dindo, Giorgia Mandrile, Carolina Conter, Rosa Montone, Daniela Giachino, Alessandra Pelle, Claudio Costantini, Barbara Cellini. The ILE56 mutation on different genetic backgrounds of alanine:glyoxylate aminotransferase: Clinical features and biochemical characterization. Molecular genetics and metabolism. 2020 Sep; 131(1-2):171-180. doi: 10.1016/j.ymgme.2020.07.012. [PMID: 32792227]
  • Zhisheng Zhang, Xiu Liang, Lei Lu, Zheng Xu, Jiayu Huang, Han He, Xinxiang Peng. Two glyoxylate reductase isoforms are functionally redundant but required under high photorespiration conditions in rice. BMC plant biology. 2020 Jul; 20(1):357. doi: 10.1186/s12870-020-02568-0. [PMID: 32727356]
  • Jasper Schierstaedt, Sven Jechalke, Joseph Nesme, Klaus Neuhaus, Søren J Sørensen, Rita Grosch, Kornelia Smalla, Adam Schikora. Salmonella persistence in soil depends on reciprocal interactions with indigenous microorganisms. Environmental microbiology. 2020 07; 22(7):2639-2652. doi: 10.1111/1462-2920.14972. [PMID: 32128943]
  • M Luisa Hernández, Elena Lima-Cabello, Juan de D Alché, José M Martínez-Rivas, Antonio J Castro. Lipid Composition and Associated Gene Expression Patterns during Pollen Germination and Pollen Tube Growth in Olive (Olea europaea L.). Plant & cell physiology. 2020 Jul; 61(7):1348-1364. doi: 10.1093/pcp/pcaa063. [PMID: 32384163]
  • Wan-Lin Wu, Yu-Yun Hsiao, Hsiang-Chia Lu, Chieh-Kai Liang, Chih-Hsiung Fu, Tian-Hsiang Huang, Ming-Hsiang Chuang, Li-Jun Chen, Zhong-Jian Liu, Wen-Chieh Tsai. Expression regulation of MALATE SYNTHASE involved in glyoxylate cycle during protocorm development in Phalaenopsis aphrodite (Orchidaceae). Scientific reports. 2020 06; 10(1):10123. doi: 10.1038/s41598-020-66932-8. [PMID: 32572104]
  • Wei Zhou, Yanli Hong, Ailing Yin, Shijia Liu, Minmin Chen, Xifeng Lv, Xiaowei Nie, Ninghua Tan, Zhihao Zhang. Non-invasive urinary metabolomics reveals metabolic profiling of polycystic ovary syndrome and its subtypes. Journal of pharmaceutical and biomedical analysis. 2020 Jun; 185(?):113262. doi: 10.1016/j.jpba.2020.113262. [PMID: 32222648]
  • Seanna L Hewitt, Rishikesh Ghogare, Amit Dhingra. Glyoxylic acid overcomes 1-MCP-induced blockage of fruit ripening in Pyrus communis L. var. 'D'Anjou'. Scientific reports. 2020 04; 10(1):7084. doi: 10.1038/s41598-020-63642-z. [PMID: 32341384]
  • Vincenzo Cuomo, Cesare Gerardo Riccio, Salvatore Coppola. [Primary hyperoxaluria: case report and therapeutic perspectives]. Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia. 2020 Feb; 37(1):. doi: NULL. [PMID: 32068359]
  • Toshiaki Kozuka, Yuji Sawada, Hiroyuki Imai, Masatake Kanai, Masami Yokota Hirai, Shoji Mano, Matsuo Uemura, Mikio Nishimura, Makoto Kusaba, Akira Nagatani. Regulation of Sugar and Storage Oil Metabolism by Phytochrome during De-etiolation. Plant physiology. 2020 02; 182(2):1114-1129. doi: 10.1104/pp.19.00535. [PMID: 31748417]
  • Dewi van Harskamp, Sander F Garrelfs, Michiel J S Oosterveld, Jaap W Groothoff, Johannes B van Goudoever, Henk Schierbeek. Development and Validation of a New Gas Chromatography-Tandem Mass Spectrometry Method for the Measurement of Enrichment of Glyoxylate Metabolism Analytes in Hyperoxaluria Patients Using a Stable Isotope Procedure. Analytical chemistry. 2020 01; 92(2):1826-1832. doi: 10.1021/acs.analchem.9b03670. [PMID: 31867958]
  • Xiaoqi Yang, Haoran Liu, Tao Ye, Chen Duan, Peng Lv, Xiaoliang Wu, Jianhe Liu, Kehua Jiang, Hongyan Lu, Huan Yang, Ding Xia, Ejun Peng, Zhiqiang Chen, Kun Tang, Zhangqun Ye. AhR activation attenuates calcium oxalate nephrocalcinosis by diminishing M1 macrophage polarization and promoting M2 macrophage polarization. Theranostics. 2020; 10(26):12011-12025. doi: 10.7150/thno.51144. [PMID: 33204326]
  • Jade Martins, Darina Czamara, Jennifer Lange, Frederik Dethloff, Elisabeth B Binder, Chris W Turck, Angelika Erhardt. Exposure-induced changes of plasma metabolome and gene expression in patients with panic disorder. Depression and anxiety. 2019 12; 36(12):1173-1181. doi: 10.1002/da.22946. [PMID: 31374578]
  • Spencer M Heuchan, Bo Fan, Jessica J Kowalski, Elizabeth R Gillies, Hugh A L Henry. Development of Fertilizer Coatings from Polyglyoxylate-Polyester Blends Responsive to Root-Driven pH Change. Journal of agricultural and food chemistry. 2019 Nov; 67(46):12720-12729. doi: 10.1021/acs.jafc.9b04717. [PMID: 31652059]
  • Yong Jia, Crista A Burbidge, Crystal Sweetman, Emi Schutz, Kathy Soole, Colin Jenkins, Robert D Hancock, John B Bruning, Christopher M Ford. An aldo-keto reductase with 2-keto-l-gulonate reductase activity functions in l-tartaric acid biosynthesis from vitamin C in Vitis vinifera. The Journal of biological chemistry. 2019 11; 294(44):15932-15946. doi: 10.1074/jbc.ra119.010196. [PMID: 31488549]
  • Mingwei Wang, Hailiang Nie, Dandan Han, Xiaoqiang Qiao, Hongyuan Yan, Shigang Shen. Cauliflower-like resin microspheres with tuneable surface roughness as solid-phase extraction adsorbent for efficient extraction and determination of plant growth regulators in cucumbers. Food chemistry. 2019 Oct; 295(?):259-266. doi: 10.1016/j.foodchem.2019.05.130. [PMID: 31174757]
  • Agnese Serafini, Lendl Tan, Stuart Horswell, Steven Howell, Daniel J Greenwood, Deborah M Hunt, Minh-Duy Phan, Mark Schembri, Mercedes Monteleone, Christine R Montague, Warwick Britton, Acely Garza-Garcia, Ambrosius P Snijders, Brian VanderVen, Maximiliano G Gutierrez, Nicholas P West, Luiz Pedro S de Carvalho. Mycobacterium tuberculosis requires glyoxylate shunt and reverse methylcitrate cycle for lactate and pyruvate metabolism. Molecular microbiology. 2019 10; 112(4):1284-1307. doi: 10.1111/mmi.14362. [PMID: 31389636]
  • Lu Wang, Huaiyuan Zhang, Yao Zhang, Yuanda Song. 13C metabolic flux analysis on roles of malate transporter in lipid accumulation of Mucor circinelloides. Microbial cell factories. 2019 Sep; 18(1):154. doi: 10.1186/s12934-019-1207-9. [PMID: 31506101]
  • Falicia Qi Yun Goh, Justin Jeyakani, Phornpimon Tipthara, Amaury Cazenave-Gassiot, Rajoshi Ghosh, Nicholas Bogard, Zhenxuan Yeo, Gane Ka-Shu Wong, Michael Melkonian, Markus R Wenk, Neil D Clarke. Gains and losses of metabolic function inferred from a phylotranscriptomic analysis of algae. Scientific reports. 2019 07; 9(1):10482. doi: 10.1038/s41598-019-46869-3. [PMID: 31324835]
  • Junhua Xi, Yang Chen, Junfeng Jing, Yanbin Zhang, Chaozhao Liang, Zongyao Hao, Li Zhang. Sirtuin 3 suppresses the formation of renal calcium oxalate crystals through promoting M2 polarization of macrophages. Journal of cellular physiology. 2019 07; 234(7):11463-11473. doi: 10.1002/jcp.27803. [PMID: 30588609]
  • Paola Faraoni, Elettra Sereni, Alessio Gnerucci, Francesca Cialdai, Monica Monici, Francesco Ranaldi. Glyoxylate cycle activity in Pinus pinea seeds during germination in altered gravity conditions. Plant physiology and biochemistry : PPB. 2019 Jun; 139(?):389-394. doi: 10.1016/j.plaphy.2019.03.042. [PMID: 30959447]
  • Teruaki Sugino, Atsushi Okada, Kazumi Taguchi, Rei Unno, Shuzo Hamamoto, Ryosuke Ando, Tohru Mogami, Kenjiro Kohri, Hitoshi Yamashita, Takahiro Yasui. Brown adipocytes and β3-stimulant-induced brown-like adipocytes contribute to the prevention of renal crystal formation. American journal of physiology. Renal physiology. 2019 06; 316(6):F1282-F1292. doi: 10.1152/ajprenal.00523.2018. [PMID: 30995115]
  • Yong Min, Wenjia Cao, Yun Xiong, Zhihao Si, Dawood Khan, Limei Chen. Formaldehyde assimilation through coordination of the glyoxylate pathway and the tricarboxylic acid cycle in broad bean roots. Plant physiology and biochemistry : PPB. 2019 May; 138(?):65-79. doi: 10.1016/j.plaphy.2019.02.019. [PMID: 30852239]
  • Anjli Kukreja, Melissa Lasaro, Christian Cobaugh, Chris Forbes, Jian-Ping Tang, Xiang Gao, Cristina Martin-Higueras, Angel L Pey, Eduardo Salido, Susan Sobolov, Romesh R Subramanian. Systemic Alanine Glyoxylate Aminotransferase mRNA Improves Glyoxylate Metabolism in a Mouse Model of Primary Hyperoxaluria Type 1. Nucleic acid therapeutics. 2019 04; 29(2):104-113. doi: 10.1089/nat.2018.0740. [PMID: 30676254]
  • Mirco Dindo, Carolina Conter, Elisa Oppici, Veronica Ceccarelli, Lorella Marinucci, Barbara Cellini. Molecular basis of primary hyperoxaluria: clues to innovative treatments. Urolithiasis. 2019 Feb; 47(1):67-78. doi: 10.1007/s00240-018-1089-z. [PMID: 30430197]
  • Masayuki Usami, Atsushi Okada, Kazumi Taguchi, Shuzo Hamamoto, Kenjiro Kohri, Takahiro Yasui. Genetic differences in C57BL/6 mouse substrains affect kidney crystal deposition. Urolithiasis. 2018 Nov; 46(6):515-522. doi: 10.1007/s00240-018-1040-3. [PMID: 29362828]
  • Yufan Chao, Songyan Gao, Xuelei Wang, Na Li, Hongxia Zhao, Xiaofei Wen, Ziyang Lou, Xin Dong. Untargeted lipidomics based on UPLC-QTOF-MS/MS and structural characterization reveals dramatic compositional changes in serum and renal lipids in mice with glyoxylate-induced nephrolithiasis. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2018 Sep; 1095(?):258-266. doi: 10.1016/j.jchromb.2018.08.003. [PMID: 30099286]
  • Alexander T Eprintsev, Dmitry N Fedorin, Maria A Dobychina, Abir U Igamberdiev. Regulation of expression of the mitochondrial and peroxisomal forms of citrate synthase in maize during germination and in response to light. Plant science : an international journal of experimental plant biology. 2018 Jul; 272(?):157-163. doi: 10.1016/j.plantsci.2018.04.017. [PMID: 29807587]
  • Manman Zhang, Chao Gao, Xiaoting Guo, Shiting Guo, Zhaoqi Kang, Dan Xiao, Jinxin Yan, Fei Tao, Wen Zhang, Wenyue Dong, Pan Liu, Chen Yang, Cuiqing Ma, Ping Xu. Increased glutarate production by blocking the glutaryl-CoA dehydrogenation pathway and a catabolic pathway involving L-2-hydroxyglutarate. Nature communications. 2018 05; 9(1):2114. doi: 10.1038/s41467-018-04513-0. [PMID: 29844506]
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  • Mahmoud El-Maghrabey, Masaki Mine, Naoya Kishikawa, Kaname Ohyama, Naotaka Kuroda. A novel dual labeling approach enables converting fluorescence labeling reagents into fluorogenic ones via introduction of purification tags. Application to determination of glyoxylic acid in serum. Talanta. 2018 Apr; 180(?):323-328. doi: 10.1016/j.talanta.2017.12.023. [PMID: 29332818]
  • Rui Zheng, Xiaoliang Fang, Lei He, Yanjiao Shao, Nana Guo, Liren Wang, Mingyao Liu, Dali Li, Hongquan Geng. Generation of a Primary Hyperoxaluria Type 1 Disease Model Via CRISPR/Cas9 System in Rats. Current molecular medicine. 2018; 18(7):436-447. doi: 10.2174/1566524019666181212092440. [PMID: 30539697]
  • Jingbo Yu, Ling Kong, Aihua Zhang, Ying Han, Zhidong Liu, Hui Sun, Liang Liu, Xijun Wang. High-Throughput Metabolomics for Discovering Potential Metabolite Biomarkers and Metabolic Mechanism from the APPswe/PS1dE9 Transgenic Model of Alzheimer's Disease. Journal of proteome research. 2017 09; 16(9):3219-3228. doi: 10.1021/acs.jproteome.7b00206. [PMID: 28753016]
  • Rosaria Campilongo, Rowena K Y Fung, Richard H Little, Lucia Grenga, Eleftheria Trampari, Simona Pepe, Govind Chandra, Clare E M Stevenson, Davide Roncarati, Jacob G Malone. One ligand, two regulators and three binding sites: How KDPG controls primary carbon metabolism in Pseudomonas. PLoS genetics. 2017 Jun; 13(6):e1006839. doi: 10.1371/journal.pgen.1006839. [PMID: 28658302]
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  • Zhongjiang Peng, Wei Chen, Li Wang, Zhouheng Ye, Songyan Gao, Xuejun Sun, Zhiyong Guo. Inhalation of hydrogen gas ameliorates glyoxylate-induced calcium oxalate deposition and renal oxidative stress in mice. International journal of clinical and experimental pathology. 2015; 8(3):2680-9. doi: NULL. [PMID: 26045773]
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