3-Deoxythymidine (BioDeep_00000897340)
代谢物信息卡片
化学式: C10H14N2O4 (226.0953524)
中文名称: 2,3-二脱氧胸苷
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CN(C(=O)NC1=O)C2CCC(O2)CO
InChI: InChI=1S/C10H14N2O4/c1-6-4-12(10(15)11-9(6)14)8-3-2-7(5-13)16-8/h4,7-8,13H,2-3,5H2,1H3,(H,11,14,15)/t7-,8+/m0/s1
描述信息
D009676 - Noxae > D000963 - Antimetabolites > D015224 - Dideoxynucleosides
同义名列表
2 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- William Lewis, Chad P Haase, Yoon K Miller, Brandy Ferguson, Tami Stuart, Tomika Ludaway, Jamie McNaught, Rodney Russ, Jeffrey Steltzer, Robert Santoianni, Robert Long, Giuseppe Fiermonte, Ferdinando Palmieri. Transgenic expression of the deoxynucleotide carrier causes mitochondrial damage that is enhanced by NRTIs for AIDS.
Laboratory investigation; a journal of technical methods and pathology.
2005 Aug; 85(8):972-81. doi:
10.1038/labinvest.3700301. [PMID: 15951836] - Margaret Q Wang, Wankee Kim, Guangxia Gao, Ted A Torrey, Herbert C Morse, Pietro De Camilli, Stephen P Goff. Endophilins interact with Moloney murine leukemia virus Gag and modulate virion production.
Journal of biology.
2003; 3(1):4. doi:
10.1186/1475-4924-3-4. [PMID: 14659004] - Z J Ma, M Yamaguchi. Stimulatory effect of zinc on deoxyribonucleic acid synthesis in bone growth of newborn rats: enhancement with zinc and insulin-like growth factor-I.
Calcified tissue international.
2001 Sep; 69(3):158-63. doi:
10.1007/s00223-001-2010-1. [PMID: 11683530] - K Y Hostetler, D D Richman, D A Carson, L M Stuhmiller, G M van Wijk, H van den Bosch. Greatly enhanced inhibition of human immunodeficiency virus type 1 replication in CEM and HT4-6C cells by 3'-deoxythymidine diphosphate dimyristoylglycerol, a lipid prodrug of 3'-deoxythymidine.
Antimicrobial agents and chemotherapy.
1992 Sep; 36(9):2025-9. doi:
10.1128/aac.36.9.2025. [PMID: 1416896] - B E Korba, J L Gerin. Use of a standardized cell culture assay to assess activities of nucleoside analogs against hepatitis B virus replication.
Antiviral research.
1992 Jul; 19(1):55-70. doi:
10.1016/0166-3542(92)90056-b. [PMID: 1444322] - E Matthes, M von Janta-Lipinski, H Will, H C Schröder, H Merz, R Steffen, W E Müller. Inhibition of hepatitis B virus production by modified 2',3'-dideoxy-thymidine and 2',3'-dideoxy-5-methylcytidine derivatives. In vitro and in vivo studies.
Biochemical pharmacology.
1992 Apr; 43(7):1571-7. doi:
10.1016/0006-2952(92)90216-6. [PMID: 1314607] - P G Plagemann, C Woffendin. Permeation and salvage of dideoxyadenosine in mammalian cells.
Molecular pharmacology.
1989 Jul; 36(1):185-92. doi:
. [PMID: 2787472] - H Alexandre. Involvement of DNA-polymerase activities in mouse-blastocyst differentiation in vitro.
Differentiation; research in biological diversity.
1985; 29(2):152-9. doi:
10.1111/j.1432-0436.1985.tb00309.x. [PMID: 3930334] - M A Waqar, M J Evans, K F Manly, R G Hughes, J A Huberman. Effects of 2',3'-dideoxynucleosides on mammalian cells and viruses.
Journal of cellular physiology.
1984 Nov; 121(2):402-8. doi:
10.1002/jcp.1041210218. [PMID: 6092393]
