1H-Imidazole-4-carboxamide, 5-amino-1-(5-O-phosphono-beta-D-ribofuranosyl)- (BioDeep_00000871834)

Main id: BioDeep_00000002270

 

human metabolite PANOMIX_OTCML-2023 blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


5-amino-1-{3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl}-1H-imidazole-4-carboximidic acid

化学式: C9H15N4O8P (338.062748)
中文名称: 5-氨基咪唑-4-甲酰胺-1-Β-D-呋喃核糖苷5-一磷酸盐
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=NC(=C(N1C2C(C(C(O2)COP(=O)(O)O)O)O)N)C(=O)N
InChI: InChI=1S/C9H15N4O8P/c10-7-4(8(11)16)12-2-13(7)9-6(15)5(14)3(21-9)1-20-22(17,18)19/h2-3,5-6,9,14-15H,1,10H2,(H2,11,16)(H2,17,18,19)

描述信息

Produced by the action of brewers yeast on the riboside. The 5-phosphate and its nontoxic salts are potent flavour enhancers of soups, canned foods, beverages, etc [DFC]. Acadesine 5-monophosphate is found in herbs and spices.

同义名列表

6 个代谢物同义名

5-amino-1-{3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl}-1H-imidazole-4-carboximidic acid; 5-amino-1-{3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl}imidazole-4-carboximidic acid; 1H-Imidazole-4-carboxamide, 5-amino-1-(5-O-phosphono-beta-D-ribofuranosyl)-; Acadesine 5-monophosphoric acid; Acadesine 5-monophosphate; Aica ribonucleotide



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Marta Fernández-Galilea, Patricia Pérez-Matute, Pedro L Prieto-Hontoria, J Alfredo Martinez, Maria J Moreno-Aliaga. Effects of lipoic acid on lipolysis in 3T3-L1 adipocytes. Journal of lipid research. 2012 Nov; 53(11):2296-306. doi: 10.1194/jlr.m027086. [PMID: 22941773]
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  • Christina A Shugrue, Martine Alexandre, Alexander Diaz de Villalvilla, Thomas R Kolodecik, Lawrence H Young, Fred S Gorelick, Edwin C Thrower. Cerulein hyperstimulation decreases AMP-activated protein kinase levels at the site of maximal zymogen activation. American journal of physiology. Gastrointestinal and liver physiology. 2012 Sep; 303(6):G723-32. doi: 10.1152/ajpgi.00082.2012. [PMID: 22821946]
  • Eun Jeong Lee, Minseok Kang, Yeong Shik Kim. Platycodin D inhibits lipogenesis through AMPKα-PPARγ2 in 3T3-L1 cells and modulates fat accumulation in obese mice. Planta medica. 2012 Sep; 78(14):1536-42. doi: 10.1055/s-0032-1315147. [PMID: 22872592]
  • Boubacar Benziane, Marie Björnholm, Sergej Pirkmajer, Reginald L Austin, Olga Kotova, Benoit Viollet, Juleen R Zierath, Alexander V Chibalin. Activation of AMP-activated protein kinase stimulates Na+,K+-ATPase activity in skeletal muscle cells. The Journal of biological chemistry. 2012 Jul; 287(28):23451-63. doi: 10.1074/jbc.m111.331926. [PMID: 22610379]
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  • Yong-Qiang Liu, Xin Cheng, Liang-Xia Guo, Chan Mao, Yi-Jie Chen, Hai-Xia Liu, Qi-Cai Xiao, Sheng Jiang, Zhu-Jun Yao, Guang-Biao Zhou. Identification of an annonaceous acetogenin mimetic, AA005, as an AMPK activator and autophagy inducer in colon cancer cells. PloS one. 2012; 7(10):e47049. doi: 10.1371/journal.pone.0047049. [PMID: 23056575]
  • Mohamed Kodiha, Dennis Ho-Wo-Cheong, Ursula Stochaj. Pharmacological AMP-kinase activators have compartment-specific effects on cell physiology. American journal of physiology. Cell physiology. 2011 Dec; 301(6):C1307-15. doi: 10.1152/ajpcell.00309.2011. [PMID: 21918180]
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  • Mamoru Tanida, Naoki Yamamoto. Central AMP-activated protein kinase affects sympathetic nerve activity in rats. Neuroscience letters. 2011 Oct; 503(3):167-70. doi: 10.1016/j.neulet.2011.08.013. [PMID: 21893163]
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  • Eun-Jeong Jung, Sung-Won Kwon, Byung-Hwa Jung, Seon-Hee Oh, Byung-Hoon Lee. Role of the AMPK/SREBP-1 pathway in the development of orotic acid-induced fatty liver. Journal of lipid research. 2011 Sep; 52(9):1617-25. doi: 10.1194/jlr.m015263. [PMID: 21757781]
  • Mandeep P Gaidhu, Andrea Frontini, Steven Hung, Kathryn Pistor, Saverio Cinti, Rolando B Ceddia. Chronic AMP-kinase activation with AICAR reduces adiposity by remodeling adipocyte metabolism and increasing leptin sensitivity. Journal of lipid research. 2011 Sep; 52(9):1702-11. doi: 10.1194/jlr.m015354. [PMID: 21737753]
  • Yanzhuo Ma, Yi Liu, Shaowei Liu, Yan Qu, Rutao Wang, Chenhai Xia, Haifeng Pei, Kun Lian, Tao Yin, Xiaoyan Lu, Lu Sun, Lu Yang, Yanjie Cao, Wayne Bond Lau, Erhe Gao, Haichang Wang, Ling Tao. Dynamic alteration of adiponectin/adiponectin receptor expression and its impact on myocardial ischemia/reperfusion in type 1 diabetic mice. American journal of physiology. Endocrinology and metabolism. 2011 Sep; 301(3):E447-55. doi: 10.1152/ajpendo.00687.2010. [PMID: 21586697]
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