HQMME (BioDeep_00000863185)

Main id: BioDeep_00000017462

 

PANOMIX_OTCML-2023


代谢物信息卡片


InChI=1\C7H8O2\c1-9-7-4-2-6(8)3-5-7\h2-5,8H,1H

化学式: C7H8O2 (124.05242679999999)
中文名称: 4-甲氧基苯酚(MEHQ)
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=CC=C(C=C1)O
InChI: InChI=1S/C7H8O2/c1-9-7-4-2-6(8)3-5-7/h2-5,8H,1H3

描述信息

D020011 - Protective Agents > D000975 - Antioxidants
C78284 - Agent Affecting Integumentary System
D000970 - Antineoplastic Agents
D - Dermatologicals
Mequinol (4-Methoxyphenol) is one of bioactive components in Mercurialis. Mequinol is used for skin depigmentation[1]
Mequinol (4-Methoxyphenol) is one of bioactive components in Mercurialis. Mequinol is used for skin depigmentation[1]

同义名列表

47 个代谢物同义名

InChI=1\C7H8O2\c1-9-7-4-2-6(8)3-5-7\h2-5,8H,1H; Mono methyl ether hydroquinone; 4-Hydroxyphenol, polymer-bound; hydroquinone monomethyl ether; Monomethyl ether hydroquinone; 1-Hydroxy-4-methoxybenzene; hydroquinone methyl ether; p-Hydroxymethoxybenzene; Mequinolum [INN-Latin]; Phenol, p-methoxy-; Phenol, 4-methoxy-; Mequinol [DCF:INN]; PMF (antioxidant); Novo-Dermoquinona; PHENOL,4-METHOXY; 4-hydroxyanisole; p-hydroxyanisole; EINECS 205-769-8; Mechinolo [DCIT]; p-Methoxyphenol; Mequinol (USAN); 4-methoxyphenol; NCGC00091390-01; 650382_ALDRICH; NCIMech_000709; M18655_ALDRICH; NCI60_004190; ZINC00001684; WLN: QR DO1; 54050_FLUKA; Leucodine B; Mechinolum; CCRIS 5531; Leucobasal; P-Guaiacol; BMS 181158; AI3-00841; HSDB 4258; USAF AN-7; Mequinol; SB 01123; 150-76-5; NSC 4960; NSC4960; D04926; HQMME; MEHQ



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

20 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

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  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Sonia Losada-Barreiro, Carlos Bravo-Díaz. Free radicals and polyphenols: The redox chemistry of neurodegenerative diseases. European journal of medicinal chemistry. 2017 Jun; 133(?):379-402. doi: 10.1016/j.ejmech.2017.03.061. [PMID: 28415050]
  • Edward J Land, Christopher A Ramsden, Patrick A Riley, Michael R L Stratford. Investigation of the anomalous action of 5-hydroxyresorcinol on tyrosinase. Pigment cell & melanoma research. 2016 07; 29(4):474-6. doi: 10.1111/pcmr.12490. [PMID: 27166874]
  • Walter A Zin, Ana G L S Silva, Clarissa B Magalhães, Giovanna M C Carvalho, Douglas R Riva, Crystianne C Lima, Jose H Leal-Cardoso, Christina M Takiya, Samuel S Valença, Paulo H N Saldiva, Débora S Faffe. Eugenol attenuates pulmonary damage induced by diesel exhaust particles. Journal of applied physiology (Bethesda, Md. : 1985). 2012 Mar; 112(5):911-7. doi: 10.1152/japplphysiol.00764.2011. [PMID: 22194320]
  • Sylvain Valère Tanemossu Sob, Hippolyte Kamdem Wabo, Chun-Ping Tang, Pierre Tane, Bonaventure Tchaleu Ngadjui, Yang Ye. Phenol esters and other constituents from the stem barks of Stereospermum acuminatissimum. Journal of Asian natural products research. 2011 Dec; 13(12):1128-34. doi: 10.1080/10286020.2011.619182. [PMID: 22008010]
  • Zhong-Duo Yang, Zhu-Wen Song, Jin Ren, Ming-Jun Yang, Shuo Li. Improved thin-layer chromatography bioautographic assay for the detection of actylcholinesterase inhibitors in plants. Phytochemical analysis : PCA. 2011 Nov; 22(6):509-15. doi: 10.1002/pca.1310. [PMID: 21433160]
  • Horacio Riojas-Rodriguez, Astrid Schilmann, Adriana Teresa Marron-Mares, Omar Masera, Zheng Li, Lovisa Romanoff, Andreas Sjödin, Leonora Rojas-Bracho, Larry L Needham, Isabelle Romieu. Impact of the improved patsari biomass stove on urinary polycyclic aromatic hydrocarbon biomarkers and carbon monoxide exposures in rural Mexican women. Environmental health perspectives. 2011 Sep; 119(9):1301-7. doi: 10.1289/ehp.1002927. [PMID: 21622083]
  • Carolina Arevalo, Ines Ruiz, Anna Lisa Piccinelli, Luca Campone, Luca Rastrelli. Phenolic derivatives from the leaves of Martinella obovata (Bignoniaceae). Natural product communications. 2011 Jul; 6(7):957-60. doi: ". [PMID: 21834232]
  • Ante Jerkovic, Alison M Kriegel, John R Bradner, Brian J Atwell, Thomas H Roberts, Robert D Willows. Strategic distribution of protective proteins within bran layers of wheat protects the nutrient-rich endosperm. Plant physiology. 2010 Mar; 152(3):1459-70. doi: 10.1104/pp.109.149864. [PMID: 20061449]
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  • Padmarajaiah Nagaraja, Anantharaman Shivakumar, Ashwinee Kumar Shrestha. Development and evaluation of kinetic spectrophotometric assays for horseradish peroxidase by catalytic coupling of paraphenylenediamine and mequinol. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2009 Oct; 25(10):1243-8. doi: 10.2116/analsci.25.1243. [PMID: 19822971]
  • Christopher T Migliaccio, Megan A Bergauff, Christopher P Palmer, Forrest Jessop, Curtis W Noonan, Tony J Ward. Urinary levoglucosan as a biomarker of wood smoke exposure: observations in a mouse model and in children. Environmental health perspectives. 2009 Jan; 117(1):74-9. doi: 10.1289/ehp.11378. [PMID: 19165390]
  • Andrea L Hinwood, Masooma Trout, John Murby, Caroline Barton, Bob Symons. Assessing urinary levoglucosan and methoxyphenols as biomarkers for use in woodsmoke exposure studies. The Science of the total environment. 2008 Aug; 402(1):139-46. doi: 10.1016/j.scitotenv.2008.04.012. [PMID: 18511108]
  • Yasmin Akhtar, Murray B Isman, Peggy M Paduraru, Srinivas Nagabandi, Ranjeet Nair, Erika Plettner. Screening of dialkoxybenzenes and disubstituted cyclopentene derivatives against the cabbage looper, Trichoplusia ni, for the discovery of new feeding and oviposition deterrents. Journal of agricultural and food chemistry. 2007 Dec; 55(25):10323-30. doi: 10.1021/jf071636d. [PMID: 18020407]
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  • Kazuhisa Maeda, Tomoko Naitou, Kenichi Umishio, Tadao Fukuhara, Akira Motoyama. A novel melanin inhibitor: hydroperoxy traxastane-type triterpene from flowers of Arnica montana. Biological & pharmaceutical bulletin. 2007 May; 30(5):873-9. doi: 10.1248/bpb.30.873. [PMID: 17473428]
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  • Tsutomu Warashina, Yoshimi Nagatani, Tadataka Noro. Constituents from the bark of Tabebuia impetiginosa. Phytochemistry. 2004 Jul; 65(13):2003-11. doi: 10.1016/j.phytochem.2004.06.012. [PMID: 15280007]
  • Clyatt E Drakeford, N Dwight Camper, Melissa B Riley. Fate of isoxaben in a containerized plant rhizosphere system. Chemosphere. 2003 Mar; 50(9):1243-7. doi: 10.1016/s0045-6535(02)00578-7. [PMID: 12547338]
  • Majid Y Moridani, Sophia S Cheon, Sumsullah Khan, Peter J O'Brien. Metabolic activation of 3-hydroxyanisole by isolated rat hepatocytes. Chemico-biological interactions. 2003 Jan; 142(3):317-33. doi: 10.1016/s0009-2797(02)00125-4. [PMID: 12453669]
  • Byeoung-Soo Park, Kwang-Geun Lee, Takayuki Shibamoto, Sung-Eun Lee, Gary R Takeoka. Antioxidant activity and characterization of volatile constituents of Taheebo (Tabebuia impetiginosa Martius ex DC). Journal of agricultural and food chemistry. 2003 Jan; 51(1):295-300. doi: 10.1021/jf020811h. [PMID: 12502424]
  • M Y Moridani, S S Cheon, S Khan, P J O'Brien. Metabolic activation of 4-hydroxyanisole by isolated rat hepatocytes. Drug metabolism and disposition: the biological fate of chemicals. 2002 Oct; 30(10):1063-9. doi: 10.1124/dmd.30.10.1063. [PMID: 12228181]
  • Michael D Hays, Christopher D Geron, Kara J Linna, N Dean Smith, James J Schauer. Speciation of gas-phase and fine particle emissions from burning of foliar fuels. Environmental science & technology. 2002 Jun; 36(11):2281-95. doi: 10.1021/es0111683. [PMID: 12075778]
  • Jan-Willem de Kraker, Maurice C R Franssen, Maaike Joerink, Aede de Groot, Harro J Bouwmeester. Biosynthesis of costunolide, dihydrocostunolide, and leucodin. Demonstration of cytochrome p450-catalyzed formation of the lactone ring present in sesquiterpene lactones of chicory. Plant physiology. 2002 May; 129(1):257-68. doi: 10.1104/pp.010957. [PMID: 12011356]
  • Carol A Lapp, George S Schuster. Effects of DMAEMA and 4-methoxyphenol on gingival fibroblast growth, metabolism, and response to interleukin-1. Journal of biomedical materials research. 2002 Apr; 60(1):30-5. doi: 10.1002/jbm.10057. [PMID: 11835156]
  • N D Camper, J H Kim, M B Riley. Degradation of isoxaben in soils and an aqueous system. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2001 Nov; 36(6):729-39. doi: 10.1081/pfc-100107407. [PMID: 11757733]
  • D W Everett, T J Franz, T J Chando, P J Gale, P A Lehman, E H Schwarzel, P V Parab, C J D'Arienzo, K J Kripalani. Percutaneous absorption of [3H]tretinoin and systemic exposure to mequinol after dermal application of 2\% mequinol/0.01\% [3H]tretinoin (Solagé) solution in healthy volunteers. Biopharmaceutics & drug disposition. 1999 Sep; 20(6):301-8. doi: 10.1002/(sici)1099-081x(199909)20:6<301::aid-bdd189>3.0.co;2-5. [PMID: 10701701]
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  • M Hirose, Y Takesada, H Tanaka, S Tamano, T Kato, T Shirai. Carcinogenicity of antioxidants BHA, caffeic acid, sesamol, 4-methoxyphenol and catechol at low doses, either alone or in combination, and modulation of their effects in a rat medium-term multi-organ carcinogenesis model. Carcinogenesis. 1998 Jan; 19(1):207-12. doi: 10.1093/carcin/19.1.207. [PMID: 9472713]
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  • S Koga, M Nakano, T Ito, Y Tomita. Importance of iron in lipid peroxidation in the tyrosinase/4-hydroxyanisole system: possible mechanism of killing of malignant melanoma cells by 4-hydroxyanisole. Biochemistry international. 1992 Mar; 26(3):397-403. doi: ". [PMID: 1627152]
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