34-74-2 (BioDeep_00000863036)
Main id: BioDeep_00000018074
PANOMIX_OTCML-2023 Industrial Pollutants
代谢物信息卡片
化学式: C12H14O4 (222.0892044)
中文名称: 邻苯二甲酸单丁酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCOC(=O)C1=CC=CC=C1C(=O)O
InChI: InChI=1S/C12H14O4/c1-2-3-8-16-12(15)10-7-5-4-6-9(10)11(13)14/h4-7H,2-3,8H2,1H3,(H,13,14)
描述信息
Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant[1][2].
Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant[1][2].
同义名列表
18 个代谢物同义名
1,2-Benzenedicarboxylic acid, monobutyl ester; 2-(butoxy-oxomethyl)benzoic acid; 2-(Butoxycarbonyl)benzoic acid; Phthalic acid, monobutyl ester; 2-butoxycarbonylbenzoic acid; Butyl hydrogen phthalate; mono-N-Butyl phthalate; Mono-n-butyl-phthalate; MONOBUTYL PHTHALATE; EINECS 205-036-2; BRN 2051402; AI3-01768; 131-70-4; NSC 8479; 34-74-2; NSC8479; MBP; MBPA
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:88522
- PubChem: 8575
- ChEMBL: CHEMBL2447930
- CAS: 131-70-4
- CAS: 34-74-2
- medchemexpress: HY-N7143
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
7 个相关的物种来源信息
- 49827 - Glycyrrhiza glabra: 10.1021/JF60214A042
- 84561 - Oecophylla smaragdina: 10.1271/BBB1961.54.3335
- 33090 - 天山雪莲: -
- 33090 - 罗汉果: -
- 33090 - 荆芥: -
- 33090 - 郁金: -
- 33090 - 麻黄: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Fulya Dal Yöntem, Sinem Ayaz, Şeyma Bulut, Ebru Hacıosmanoğlu Aldoğan, Müfide Aydoğan Ahbab. Endoplasmic reticulum stress and pro-inflammatory responses induced by phthalate metabolites monoethylhexyl phthalate and monobutyl phthalate in 1.1B4 pancreatic beta cells.
Toxicology.
2024 Jan; 501(?):153695. doi:
10.1016/j.tox.2023.153695
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Environmental science & technology.
2023 Jun; ?(?):. doi:
10.1021/acs.est.2c09737
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Environmental science & technology.
2023 Feb; ?(?):. doi:
10.1021/acs.est.2c07656
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Environmental toxicology.
2023 Jan; ?(?):. doi:
10.1002/tox.23734
. [PMID: 36602389] - Xiaoying Guo, Yu Hao, Huiying Ma, Hai Li, Liping Li, Fengmei Yan, Jing Huang, Ling Li. The mechanism of monobutyl phthalate -induced ferroptosis via TNF/IL6/STAT3 signal pathway in TM-3 cells.
The Journal of toxicological sciences.
2023; 48(5):299-310. doi:
10.2131/jts.48.299
. [PMID: 37121744] - Quang Luu Quoc, Tra Cao Thi Bich, Seo-Hee Kim, Min Sook Ryu, Hae-Sim Park, Yoo Seob Shin. Mono-n-butyl phthalate regulates nuclear factor erythroid 2-related factor 2 and nuclear factor kappa B pathway in an ovalbumin-induced asthma mouse model.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2022 Aug; 166(?):113171. doi:
10.1016/j.fct.2022.113171
. [PMID: 35609737] - Estela J Jauregui, Jasmine Lock, Lindsay Rasmussen, Zelieann R Craig. Mono-n-Butyl Phthalate Distributes to the Mouse Ovary and Liver and Alters the Expression of Phthalate-Metabolizing Enzymes in Both Tissues.
Toxicological sciences : an official journal of the Society of Toxicology.
2021 08; 183(1):117-127. doi:
10.1093/toxsci/kfab085
. [PMID: 34175954] - Ying Zhang, Yaqi Jiao, Yue Tao, Zixu Li, Hui Yu, Siyue Han, Yang Yang. Monobutyl phthalate can induce autophagy and metabolic disorders by activating the ire1a-xbp1 pathway in zebrafish liver.
Journal of hazardous materials.
2021 06; 412(?):125243. doi:
10.1016/j.jhazmat.2021.125243
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Reproductive toxicology (Elmsford, N.Y.).
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Ecotoxicology and environmental safety.
2021 Jun; 215(?):112174. doi:
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Journal of analytical toxicology.
2020 May; 44(4):370-377. doi:
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Chemosphere.
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Environmental health perspectives.
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Chemosphere.
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Environment international.
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BMC pediatrics.
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Environmental science and pollution research international.
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Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.
2019 Apr; 35(4):364-367. doi:
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Toxicological sciences : an official journal of the Society of Toxicology.
2019 03; 168(1):78-94. doi:
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The Science of the total environment.
2019 Mar; 654(?):1350-1357. doi:
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Environmental science and pollution research international.
2019 Mar; 26(8):7763-7771. doi:
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Chemical research in toxicology.
2019 02; 32(2):333-340. doi:
10.1021/acs.chemrestox.8b00361
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Environment international.
2019 02; 123(?):20-28. doi:
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Journal of exposure science & environmental epidemiology.
2019 01; 29(1):71-82. doi:
10.1038/s41370-018-0029-x
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Environment international.
2018 12; 121(Pt 1):538-549. doi:
10.1016/j.envint.2018.09.027
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Oncology reports.
2018 Nov; 40(5):2766-2777. doi:
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Environmental pollution (Barking, Essex : 1987).
2018 Oct; 241(?):969-977. doi:
10.1016/j.envpol.2018.06.022
. [PMID: 30029331] - Giovanna Tranfo, Lidia Caporossi, Daniela Pigini, Silvia Capanna, Bruno Papaleo, Enrico Paci. Temporal Trends of Urinary Phthalate Concentrations in Two Populations: Effects of REACH Authorization after Five Years.
International journal of environmental research and public health.
2018 09; 15(9):. doi:
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. [PMID: 30200671] - Paulina Sicińska. Di-n-butyl phthalate, butylbenzyl phthalate and their metabolites induce haemolysis and eryptosis in human erythrocytes.
Chemosphere.
2018 Jul; 203(?):44-53. doi:
10.1016/j.chemosphere.2018.03.161
. [PMID: 29605748] - Kyung-Shin Lee, Youn-Hee Lim, Kyoung-Nam Kim, Yoon-Hyeong Choi, Yun-Chul Hong, Nami Lee. Urinary phthalate metabolites concentrations and symptoms of depression in an elderly population.
The Science of the total environment.
2018 Jun; 625(?):1191-1197. doi:
10.1016/j.scitotenv.2017.12.219
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Environment international.
2018 04; 113(?):177-183. doi:
10.1016/j.envint.2018.02.004
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Chemosphere.
2018 Feb; 193(?):394-402. doi:
10.1016/j.chemosphere.2017.11.019
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Environmental pollution (Barking, Essex : 1987).
2017 Dec; 231(Pt 1):694-702. doi:
10.1016/j.envpol.2017.08.034
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Environmental health perspectives.
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Epidemiology (Cambridge, Mass.).
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Environmental health : a global access science source.
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Environmental health : a global access science source.
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International journal of environmental research and public health.
2017 02; 14(2):. doi:
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Environmental pollution (Barking, Essex : 1987).
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Human reproduction (Oxford, England).
2017 01; 32(1):232-238. doi:
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Environmental pollution (Barking, Essex : 1987).
2016 Nov; 218(?):410-418. doi:
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International journal of environmental research and public health.
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Environmental pollution (Barking, Essex : 1987).
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Biological trace element research.
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Analytical and bioanalytical chemistry.
2015 Sep; 407(24):7391-400. doi:
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Environmental science & technology.
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Environmental science & technology.
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The Journal of clinical endocrinology and metabolism.
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Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine].
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Reproductive toxicology (Elmsford, N.Y.).
2014 Aug; 47(?):70-6. doi:
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. [PMID: 24945889] - Ulla Nordström Joensen, Niels Jørgensen, Michael Meldgaard, Hanne Frederiksen, Anna-Maria Andersson, Torkil Menné, Jeanne Duus Johansen, Berit Christina Carlsen, Steen Stender, Pal Bela Szecsi, Niels Erik Skakkebæk, Ewa Rajpert-De Meyts, Jacob P Thyssen. Associations of filaggrin gene loss-of-function variants with urinary phthalate metabolites and testicular function in young Danish Men.
Environmental health perspectives.
2014 Apr; 122(4):345-50. doi:
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Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine].
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