Oligomycin (BioDeep_00000008597)

 

Secondary id: BioDeep_00000897266

Chemicals and Drugs


代谢物信息卡片


Oligomycin A

化学式: C45H74O11 (790.5230854)
中文名称: 寡霉素A 来源于 淀粉酶产色链霉菌
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCC1C=CC=CCC(C)C(O)C(C)(O)C(=O)C(C)C(O)C(C)C(=O)C(C)C(O)C(C)C=CC(=O)OC2C(C)C(CC1)OC1(CCC(C)C(CC(C)O)O1)C2C
InChI:

描述信息

Oligomycin A (MCH 32), created by Streptomyces, acts as a mitochondrial F0F1-ATPase inhibitor, with a Ki of 1 μM; Oligomycin A shows anti-fungal activity.

同义名列表

3 个代谢物同义名

Oligomycin A; Oligomycin; MCH 32



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Yan-Ran Sheng, Wen-Ting Hu, Hui-Hui Shen, Chun-Yan Wei, Yu-Kai Liu, Xiao-Qian Ma, Ming-Qing Li, Xiao-Yong Zhu. An imbalance of the IL-33/ST2-AXL-efferocytosis axis induces pregnancy loss through metabolic reprogramming of decidual macrophages. Cellular and molecular life sciences : CMLS. 2022 Mar; 79(3):173. doi: 10.1007/s00018-022-04197-2. [PMID: 35244789]
  • Wenjun Lin, Cheng Qiao, Jinghua Hu, Qing Wei, Tao Xu. Conserved role of ATP synthase in mammalian cilia. Experimental cell research. 2021 04; 401(1):112520. doi: 10.1016/j.yexcr.2021.112520. [PMID: 33639177]
  • Kazuki Harada, Takami Chihara, Yuki Hayasaka, Marie Mita, Mai Takizawa, Kentaro Ishida, Mary Arai, Saki Tsuno, Mitsuharu Matsumoto, Takeshi Ishihara, Hiroshi Ueda, Tetsuya Kitaguchi, Takashi Tsuboi. Green fluorescent protein-based lactate and pyruvate indicators suitable for biochemical assays and live cell imaging. Scientific reports. 2020 11; 10(1):19562. doi: 10.1038/s41598-020-76440-4. [PMID: 33177605]
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  • Hu Wang, Fanny Cheung, Anna C Stoll, Patricia Rockwell, Maria E Figueiredo-Pereira. Mitochondrial and calcium perturbations in rat CNS neurons induce calpain-cleavage of Parkin: Phosphatase inhibition stabilizes pSer65Parkin reducing its calpain-cleavage. Biochimica et biophysica acta. Molecular basis of disease. 2019 06; 1865(6):1436-1450. doi: 10.1016/j.bbadis.2019.02.016. [PMID: 30796971]
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  • Jun Gao, Tian Zhang, Zhanfang Kang, Weijen Ting, Lingqing Xu, Dazhong Yin. The F0F1 ATP synthase regulates human neutrophil migration through cytoplasmic proton extrusion coupled with ATP generation. Molecular immunology. 2017 10; 90(?):219-226. doi: 10.1016/j.molimm.2017.08.004. [PMID: 28843171]
  • Jaime Santo-Domingo, Isabelle Chareyron, Loïc Dayon, Antonio Núñez Galindo, Ornella Cominetti, María Pilar Giner Giménez, Umberto De Marchi, Carles Canto, Martin Kussmann, Andreas Wiederkehr. Coordinated activation of mitochondrial respiration and exocytosis mediated by PKC signaling in pancreatic β cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2017 03; 31(3):1028-1045. doi: 10.1096/fj.201600837r. [PMID: 27927723]
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