Depsidone (BioDeep_00000844916)

   

natural product


代谢物信息卡片


Depsidone

  化学式: C13H8O3 (212.0473)
中文名称: 德普西酮
  谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C2C(=C1)C(=O)OC3=CC=CC=C3O2
InChI: InChI=1S/C13H8O3/c14-13-9-5-1-2-6-10(9)15-11-7-3-4-8-12(11)16-13/h1-8H


描述信息

The simplest member of the class of depsidones comprising of a heterotricyclic system that is 11H-dibenzo[b,e][1,4]dioxepine substituted by an oxo group at position 11.

同义名列表

2 个代谢物同义名

Depsidone; Depsidone



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

7 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Feng-Zhi Shi, Yin-Dong Fang, Min Fan, Xian-Jun Jiang, Shuang Wang, Guo-Zhu Wei. Cytotoxic depsidones and xanthones from Garcinia esculenta Y. H. Li. Fitoterapia. 2024 Jan; 172(?):105779. doi: 10.1016/j.fitote.2023.105779. [PMID: 38104910]
  • Rui-Jie He, Ya-Feng Wang, Bing-Yuan Yang, Zhang-Bin Liu, Dian-Peng Li, Bi-Qun Zou, Yong-Lin Huang. Structural Characterization and Assessment of Anti-Inflammatory Activities of Polyphenols and Depsidone Derivatives from Melastoma malabathricum subsp. normale. Molecules (Basel, Switzerland). 2022 Feb; 27(5):. doi: 10.3390/molecules27051521. [PMID: 35268622]
  • Darwati Darwati, Ayu Nadila Safitri, Nurul Ambardhani, Tri Mayanti, Nurlelasari Nurlelasari, Dikdik Kurnia. Effectiveness and Anticancer Activity of a Novel Phenolic Compound from Garcinia porrecta Against the MCF-7 Breast Cancer Cell Line in vitro and in silico. Drug design, development and therapy. 2021; 15(?):3523-3533. doi: 10.2147/dddt.s321824. [PMID: 34408404]
  • Asshaima Paramita Devi, Thuc-Huy Duong, Solenn Ferron, Mehdi A Beniddir, Minh-Hiep Dinh, Van-Kieu Nguyen, Nguyen-Kim-Tuyen Pham, Dinh-Hung Mac, Joël Boustie, Warinthorn Chavasiri, Pierre Le Pogam. Salazinic Acid-Derived Depsidones and Diphenylethers with α-Glucosidase Inhibitory Activity from the Lichen Parmotrema dilatatum. Planta medica. 2020 Nov; 86(16):1216-1224. doi: 10.1055/a-1203-0623. [PMID: 32819010]
  • Thuc-Huy Duong, Tai-Xuan-Hoa Hang, Pierre Le Pogam, Thanh-Nha Tran, Dinh-Hung Mac, Minh-Hiep Dinh, Jirapast Sichaem. α-Glucosidase Inhibitory Depsidones from the Lichen Parmotrema tsavoense. Planta medica. 2020 Jul; 86(11):776-781. doi: 10.1055/a-1179-1050. [PMID: 32483775]
  • Zuzana Solárová, Alena Liskova, Marek Samec, Peter Kubatka, Dietrich Büsselberg, Peter Solár. Anticancer Potential of Lichens' Secondary Metabolites. Biomolecules. 2020 01; 10(1):. doi: 10.3390/biom10010087. [PMID: 31948092]
  • Vatcharin Rukachaisirikul, Supaporn Chinpha, Praphatsorn Saetang, Souwalak Phongpaichit, Siriporn Jungsuttiwong, Sarinya Hadsadee, Jariya Sakayaroj, Sita Preedanon, Prapapan Temkitthawon, Kornkanok Ingkaninan. Depsidones and a dihydroxanthenone from the endophytic fungi Simplicillium lanosoniveum (J.F.H. Beyma) Zare & W. Gams PSU-H168 and PSU-H261. Fitoterapia. 2019 Oct; 138(?):104286. doi: 10.1016/j.fitote.2019.104286. [PMID: 31394164]
  • Rostanie Dongmo Zeukang, Xavier Siwe-Noundou, Maurice Tagatsing Fotsing, Turibio Tabopda Kuiate, Joseph Tanyi Mbafor, Rui W M Krause, Muhammad Iqbal Choudhary, Alex de Théodore Atchadé. Cordidepsine is A Potential New Anti-HIV Depsidone from Cordia millenii, Baker. Molecules (Basel, Switzerland). 2019 Sep; 24(17):. doi: 10.3390/molecules24173202. [PMID: 31484419]
  • Jinkui Ouyang, Ziling Mao, Hui Guo, Yunying Xie, Zehua Cui, Jian Sun, Huixiong Wu, Xiujun Wen, Jun Wang, Tijiang Shan. Mollicellins O⁻R, Four New Depsidones Isolated from the Endophytic Fungus Chaetomium sp. Eef-10. Molecules (Basel, Switzerland). 2018 Dec; 23(12):. doi: 10.3390/molecules23123218. [PMID: 30563178]
  • Alain Meli Lannang, Denis Kehdinga Sema, Simplice J N Tatsimo, V F Tsague Tankeu, Hycienth F Tegha, Jean Duplex Wansi, Yoshihito Shiono, Norbert Sewald. A new depsidone derivative from the leaves of Garcinia polyantha. Natural product research. 2018 May; 32(9):1033-1038. doi: 10.1080/14786419.2017.1378201. [PMID: 28931317]
  • Praphatsorn Saetang, Vatcharin Rukachaisirikul, Souwalak Phongpaichit, Sita Preedanon, Jariya Sakayaroj, Suparerk Borwornpinyo, Sawinee Seemakhan, Chatchai Muanprasat. Depsidones and an α-pyrone derivative from Simplicillium sp. PSU-H41, an endophytic fungus from Hevea brasiliensis leaf [corrected]. Phytochemistry. 2017 11; 143(?):115-123. doi: 10.1016/j.phytochem.2017.08.002. [PMID: 28803995]
  • Edwin Risky Sukandar, Pongpun Siripong, Suttira Khumkratok, Santi Tip-Pyang. New depsidones and xanthone from the roots of Garcinia schomburgkiana. Fitoterapia. 2016 Jun; 111(?):73-7. doi: 10.1016/j.fitote.2016.04.012. [PMID: 27102610]
  • Kyoungran Lee, Joung-Han Yim, Hong-Kum Lee, Suhkneung Pyo. Inhibition of VCAM-1 expression on mouse vascular smooth muscle cells by lobastin via downregulation of p38, ERK 1/2 and NF-κB signaling pathways. Archives of pharmacal research. 2016 Jan; 39(1):83-93. doi: 10.1007/s12272-015-0687-3. [PMID: 26597859]
  • Chongming Wu, Ran Chen, Mingyue Liu, Dong Liu, Xin Li, Shuai Wang, Siwen Niu, Peng Guo, Wenhan Lin. Spiromastixones Inhibit Foam Cell Formation via Regulation of Cholesterol Efflux and Uptake in RAW264.7 Macrophages. Marine drugs. 2015 Oct; 13(10):6352-65. doi: 10.3390/md13106352. [PMID: 26473890]
  • Timo D Stark, Mathias Salger, Oliver Frank, Onesmo B Balemba, Junichiro Wakamatsu, Thomas Hofmann. Antioxidative compounds from Garcinia buchananii stem bark. Journal of natural products. 2015 Feb; 78(2):234-40. doi: 10.1021/np5007873. [PMID: 25625705]
  • Oue-artorn Rajachan, Somdej Kanokmedhakul, Kwanjai Kanokmedhakul, Kasem Soytong. Bioactive depsidones from the fungus Pilobolus heterosporus. Planta medica. 2014 Nov; 80(17):1635-40. doi: 10.1055/s-0034-1383082. [PMID: 25248047]
  • Festus Basden C Okoye, Chukwuemeka S Nworu, Peter A Akah, Charles O Esimone, Abdessamad Debbab, Peter Proksch. Inhibition of inflammatory mediators and reactive oxygen and nitrogen species by some depsidones and diaryl ether derivatives isolated from Corynespora cassiicola, an endophytic fungus of Gongronema latifolium leaves. Immunopharmacology and immunotoxicology. 2013 Dec; 35(6):662-8. doi: 10.3109/08923973.2013.834930. [PMID: 24041314]
  • Ingrid Ramírez, Soledad Araya, Marisa Piovano, Marcela Carvajal, Alvaro Cuadros-Inostroza, Luis Espinoza, Juan Antonio Garbarino, Hugo Peña-Cortés. Lichen depsides and depsidones reduce symptoms of diseases caused by tobacco mosaic virus (TMV) in tobacco leaves. Natural product communications. 2012 May; 7(5):603-6. doi: ". [PMID: 22799086]
  • Ly Dieu Ha, Poul Erik Hansen, Fritz Duus, Hung Dinh Pham, Lien-Hoa D Nguyen. Oliveridepsidones A-D, antioxidant depsidones from Garcinia oliveri. Magnetic resonance in chemistry : MRC. 2012 Mar; 50(3):242-5. doi: 10.1002/mrc.2862. [PMID: 22407733]
  • Hiroshi Furukawa. [Search of novel bioactive natural products from plant sources--novel structures and biological activities--]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2009 Oct; 129(10):1155-75. doi: 10.1248/yakushi.129.1155. [PMID: 19797871]
  • Changon Seo, Jae Hak Sohn, Jong Seog Ahn, Joung Han Yim, Hong Kum Lee, Hyuncheol Oh. Protein tyrosine phosphatase 1B inhibitory effects of depsidone and pseudodepsidone metabolites from the Antarctic lichen Stereocaulon alpinum. Bioorganic & medicinal chemistry letters. 2009 May; 19(10):2801-3. doi: 10.1016/j.bmcl.2009.03.108. [PMID: 19362837]
  • Janine Meister, Daniela Weber, Virginia Martino, Olov Sterner, Timm Anke. Phomopsidone, a novel depsidone from an endophyte of the medicinal plant Eupatorium arnottianum. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2007 Jan; 62(1-2):11-5. doi: 10.1515/znc-2007-1-202. [PMID: 17425098]
  • C Ito, M Itoigawa, Y Mishina, H Tomiyasu, M Litaudon, J P Cosson, T Mukainaka, H Tokuda, H Nishino, H Furukawa. Cancer chemopreventive agents. New depsidones from Garcinia plants. Journal of natural products. 2001 Feb; 64(2):147-50. doi: 10.1021/np000333+. [PMID: 11429990]
  • M E Hidalgo, E Fernández, W Quilhot, E Lissi. Antioxidant activity of depsides and depsidones. Phytochemistry. 1994 Dec; 37(6):1585-7. doi: 10.1016/s0031-9422(00)89571-0. [PMID: 7765999]