Salvinorin B (BioDeep_00000843708)

   

natural product


代谢物信息卡片


Salvinorin B

化学式: C21H26O7 (390.1678446)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC12CCC3C(=O)OC(CC3(C1C(=O)C(CC2C(=O)OC)O)C)C4=COC=C4
InChI: InChI=1S/C21H26O7/c1-20-6-4-12-19(25)28-15(11-5-7-27-10-11)9-21(12,2)17(20)16(23)14(22)8-13(20)18(24)26-3/h5,7,10,12-15,17,22H,4,6,8-9H2,1-3H3/t12-,13-,14-,15-,17-,20-,21-/m0/s1

描述信息

同义名列表

1 个代谢物同义名

Salvinorin B



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

18 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Maciej Jakobina, Jacek Łyczko, Antoni Szumny, Renata Galek. The influence of cultivation conditions on the formation of psychoactive salvinorin A, salvinorin B, rosmarinic acid and caffeic acid in Coleus scutellarioides. Scientific reports. 2024 03; 14(1):6693. doi: 10.1038/s41598-024-57399-y. [PMID: 38509159]
  • Eyal Vardy, J Elliott Robinson, Chia Li, Reid H J Olsen, Jeffrey F DiBerto, Patrick M Giguere, Flori M Sassano, Xi-Ping Huang, Hu Zhu, Daniel J Urban, Kate L White, Joseph E Rittiner, Nicole A Crowley, Kristen E Pleil, Christopher M Mazzone, Philip D Mosier, Juan Song, Thomas L Kash, C J Malanga, Michael J Krashes, Bryan L Roth. A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior. Neuron. 2015 May; 86(4):936-946. doi: 10.1016/j.neuron.2015.03.065. [PMID: 25937170]
  • Fernando Xavier Moreira, Félix Carvalho, Maria de Lourdes Bastos, Paula Guedes de Pinho. Analytical investigation of legal high products containing Salvia divinorum traded in smartshops and internet. Forensic science international. 2014 Sep; 242(?):255-260. doi: 10.1016/j.forsciint.2014.07.009. [PMID: 25093918]
  • John L Krstenansky, Miguel Muzzio. Analysis of the smoke of cigarettes containing Salvia divinorum. Journal of analytical toxicology. 2014 Sep; 38(7):451-5. doi: 10.1093/jat/bku054. [PMID: 24908261]
  • Madan Kumar Paudel, Osamu Shirota, Kaori Sasaki-Tabata, Hiroyuki Tanaka, Setsuko Sekita, Satoshi Morimoto. Development of an enzyme immunoassay using a monoclonal antibody against the psychoactive diterpenoid salvinorin A. Journal of natural products. 2013 Sep; 76(9):1654-60. doi: 10.1021/np400358n. [PMID: 23987562]
  • Prabhakar R Polepally, Kate White, Eyal Vardy, Bryan L Roth, Daneel Ferreira, Jordan K Zjawiony. Kappa-opioid receptor-selective dicarboxylic ester-derived salvinorin A ligands. Bioorganic & medicinal chemistry letters. 2013 May; 23(10):2860-2. doi: 10.1016/j.bmcl.2013.03.111. [PMID: 23587424]
  • Jacob M Hooker, Thomas A Munro, Cécile Béguin, David Alexoff, Colleen Shea, Youwen Xu, Bruce M Cohen. Salvinorin A and derivatives: protection from metabolism does not prolong short-term, whole-brain residence. Neuropharmacology. 2009 Sep; 57(4):386-91. doi: 10.1016/j.neuropharm.2009.06.044. [PMID: 19591852]
  • K Tsujikawa, K Kuwayama, H Miyaguchi, T Kanamori, Y T Iwata, H Inoue. In vitro stability and metabolism of salvinorin A in rat plasma. Xenobiotica; the fate of foreign compounds in biological systems. 2009 May; 39(5):391-8. doi: 10.1080/00498250902769967. [PMID: 19280383]
  • Kenji Tsujikawa, Kenji Kuwayama, Hajime Miyaguchi, Tatsuyuki Kanamori, Yuko T Iwata, Takemi Yoshida, Hiroyuki Inoue. Determination of salvinorin A and salvinorin B in Salvia divinorum-related products circulated in Japan. Forensic science international. 2008 Sep; 180(2-3):105-9. doi: 10.1016/j.forsciint.2008.07.008. [PMID: 18768273]
  • Yulin Wang, Yong Chen, Wei Xu, David Y W Lee, Zhongze Ma, Scott M Rawls, Alan Cowan, Lee-Yuan Liu-Chen. 2-Methoxymethyl-salvinorin B is a potent kappa opioid receptor agonist with longer lasting action in vivo than salvinorin A. The Journal of pharmacology and experimental therapeutics. 2008 Mar; 324(3):1073-83. doi: 10.1124/jpet.107.132142. [PMID: 18089845]
  • Michael A Ansonoff, Jiwen Zhang, Traci Czyzyk, Richard B Rothman, Jeremy Stewart, Heng Xu, Jordan Zjwiony, Daniel J Siebert, Feng Yang, Bryan L Roth, John E Pintar. Antinociceptive and hypothermic effects of Salvinorin A are abolished in a novel strain of kappa-opioid receptor-1 knockout mice. The Journal of pharmacology and experimental therapeutics. 2006 Aug; 318(2):641-8. doi: 10.1124/jpet.106.101998. [PMID: 16672569]
  • Wayne W Harding, Matthew Schmidt, Kevin Tidgewell, Pavitra Kannan, Kenneth G Holden, Brian Gilmour, Hernan Navarro, Richard B Rothman, Thomas E Prisinzano. Synthetic studies of neoclerodane diterpenes from Salvia divinorum: semisynthesis of salvinicins A and B and other chemical transformations of salvinorin A. Journal of natural products. 2006 Jan; 69(1):107-12. doi: 10.1021/np050398i. [PMID: 16441078]