Trichloromethyl radical (BioDeep_00000840621)
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: CCl3 (116.90655900000002)
中文名称:
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 7.84%
分子结构信息
SMILES: [C](Cl)(Cl)Cl
InChI: InChI=1S/CCl3/c2-1(3)4
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
1 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(1)
- carbon tetrachloride degradation II:
A(H2) + carbon tetrachloride ⟶ A + H+ + chloride + trichloromethyl radical
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Sadiq S Moree, J Rajesha. Investigation of in vitro and in vivo antioxidant potential of secoisolariciresinol diglucoside.
Molecular and cellular biochemistry.
2013 Jan; 373(1-2):179-87. doi:
10.1007/s11010-012-1487-4
. [PMID: 23108790] - Soo-Jung Kim, Ji-Hyun Park, Kyung-Hyun Kim, Woo-Ram Lee, Young-Chae Chang, Kwan-Kyu Park, Kwang-Gill Lee, Sang-Mi Han, Joo-Hong Yeo, Sok Cheon Pak. Bee venom inhibits hepatic fibrosis through suppression of pro-fibrogenic cytokine expression.
The American journal of Chinese medicine.
2010; 38(5):921-35. doi:
10.1142/s0192415x10008354
. [PMID: 20821823] - Yasusuke Masuda. [Learning toxicology from carbon tetrachloride-induced hepatotoxicity].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
2006 Oct; 126(10):885-99. doi:
10.1248/yakushi.126.885
. [PMID: 17016019] - Geng Tao Liu, Yan Li, Huai Ling Wei, Hui Zhang, Ji Yan Xu, Ling Hong Yu. Mechanism of protective action of bicyclol against CCl-induced liver injury in mice.
Liver international : official journal of the International Association for the Study of the Liver.
2005 Aug; 25(4):872-9. doi:
10.1111/j.1478-3231.2005.01103.x
. [PMID: 15998439] - G D Castro, M I Díaz Gómez, J A Castro. DNA bases attack by reactive metabolites produced during carbon tetrachloride biotransformation and promotion of liver microsomal lipid peroxidation.
Research communications in molecular pathology and pharmacology.
1997 Mar; 95(3):253-8. doi:
. [PMID: 9144833]
- K D Asmus, R V Bensasson, J L Bernier, R Houssin, E J Land. One-electron oxidation of ergothioneine and analogues investigated by pulse radiolysis: redox reaction involving ergothioneine and vitamin C.
The Biochemical journal.
1996 Apr; 315 ( Pt 2)(?):625-9. doi:
10.1042/bj3150625
. [PMID: 8615839] - O I Aruoma, J P Spencer, J Butler, B Halliwell. Reaction of plant-derived and synthetic antioxidants with trichloromethylperoxyl radicals.
Free radical research.
1995 Feb; 22(2):187-90. doi:
10.3109/10715769509147538
. [PMID: 7704187] - L E Rikans, K R Hornbrook, Y Cai. Carbon tetrachloride hepatotoxicity as a function of age in female Fischer 344 rats.
Mechanisms of ageing and development.
1994 Oct; 76(2-3):89-99. doi:
10.1016/0047-6374(94)91584-9
. [PMID: 7885069] - M Tezuka, S Ishii, S Okada. Chromium (III) decreases carbon tetrachloride-originated trichloromethyl radical in mice.
Journal of inorganic biochemistry.
1991 Dec; 44(4):261-5. doi:
10.1016/0162-0134(91)84031-4
. [PMID: 1662710] - P B McCay, G Brueggemann, E K Lai, S R Powell. Evidence that alpha-tocopherol functions cyclically to quench free radicals in hepatic microsomes. Requirement for glutathione and a heat-labile factor.
Annals of the New York Academy of Sciences.
1989; 570(?):32-45. doi:
10.1111/j.1749-6632.1989.tb14906.x
. [PMID: 2629601] - L A Reinke, E K Lai, P B McCay. Ethanol feeding stimulates trichloromethyl radical formation from carbon tetrachloride in liver.
Xenobiotica; the fate of foreign compounds in biological systems.
1988 Nov; 18(11):1311-8. doi:
10.3109/00498258809042255
. [PMID: 3245227] - B Rush, M V Merritt, M Kaluzny, T Van Schoick, M N Brunden, M Ruwart. Studies on the mechanism of the protective action of 16,16-dimethylPGE2 in carbon tetrachloride induced acute hepatic injury in the rat.
Prostaglandins.
1986 Sep; 32(3):439-55. doi:
10.1016/0090-6980(86)90011-0
. [PMID: 3786805] - T F Slater, K H Cheeseman, K U Ingold. Carbon tetrachloride toxicity as a model for studying free-radical mediated liver injury.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
1985 Dec; 311(1152):633-45. doi:
10.1098/rstb.1985.0169
. [PMID: 2869522]