Methanesulfonate (BioDeep_00000840461)
代谢物信息卡片
化学式: CH3O3S- (94.9802908)
中文名称: 甲基磺酸
谱图信息:
最多检出来源 Viridiplantae(plant) 75%
分子结构信息
SMILES: CS(=O)(=O)[O-]
InChI: InChI=1S/CH4O3S/c1-5(2,3)4/h1H3,(H,2,3,4)/p-1
描述信息
A 1,1-diunsubstituted alkanesulfonate that is the conjugate base of methanesulfonic acid.
同义名列表
1 个代谢物同义名
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(3)
PlantCyc(0)
代谢反应
23 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(4)
- methanesulfonate degradation:
NADH + O2 + methanesulfonate ⟶ H2O + NAD+ + formaldehyde + sulfite
- dimethyl sulfide degradation II (oxidation):
H+ + NADPH + O2 + dimethyl sulfide ⟶ H2O + NADP+ + dimethyl sulfoxide
- methanesulfonate degradation:
NADH + O2 + methanesulfonate ⟶ H2O + NAD+ + formaldehyde + sulfite
- methanesulfonate degradation:
NADH + O2 + methanesulfonate ⟶ H2O + NAD+ + formaldehyde + sulfite
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(17)
- glucosinolate biosynthesis from homomethionine:
H2O + O2 + glucoiberin ⟶ 3-hydroxypropyl-glucosinolate + H+ + methanesulfonate
- glucosinolate biosynthesis from homomethionine:
(E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine + H2O ⟶ (E)-ω-(methylsulfanyl)butyl-thiohydroximate + ammonium + pyruvate
- glucosinolate biosynthesis from homomethionine:
(E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine + H2O ⟶ (E)-ω-(methylsulfanyl)butyl-thiohydroximate + ammonium + pyruvate
- glucosinolate biosynthesis from homomethionine:
(E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine + H2O ⟶ (E)-ω-(methylsulfanyl)butyl-thiohydroximate + ammonium + pyruvate
- glucosinolate biosynthesis from homomethionine:
(E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine + H2O ⟶ (E)-ω-(methylsulfanyl)butyl-thiohydroximate + ammonium + pyruvate
- glucosinolate biosynthesis from homomethionine:
(E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine + H2O ⟶ (E)-ω-(methylsulfanyl)butyl-thiohydroximate + ammonium + pyruvate
- glucosinolate biosynthesis from homomethionine:
(E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine + H2O ⟶ (E)-ω-(methylsulfanyl)butyl-thiohydroximate + ammonium + pyruvate
- glucosinolate biosynthesis from homomethionine:
O2 + glucoiberin ⟶ H+ + methanesulfonate + sinigrin
- glucosinolate biosynthesis from homomethionine:
(Z)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine + H2O ⟶ (Z)-ω-(methylsulfanyl)butyl-thiohydroximate + ammonium + pyruvate
- glucosinolate biosynthesis from homomethionine:
(E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine + H2O ⟶ (E)-ω-(methylsulfanyl)butyl-thiohydroximate + ammonium + pyruvate
- glucosinolate biosynthesis from homomethionine:
H2O + O2 + glucoiberin ⟶ 3-hydroxypropyl-glucosinolate + H+ + methanesulfonate
- glucosinolate biosynthesis from homomethionine:
(E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine + H2O ⟶ (E)-ω-(methylsulfanyl)butyl-thiohydroximate + ammonium + pyruvate
- glucosinolate biosynthesis from homomethionine:
(E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine + H2O ⟶ (E)-ω-(methylsulfanyl)butyl-thiohydroximate + ammonium + pyruvate
- glucosinolate biosynthesis from homomethionine:
(E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine + H2O ⟶ (E)-ω-(methylsulfanyl)butyl-thiohydroximate + ammonium + pyruvate
- glucosinolate biosynthesis from homomethionine:
(E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine + H2O ⟶ (E)-ω-(methylsulfanyl)butyl-thiohydroximate + ammonium + pyruvate
- glucosinolate biosynthesis from homomethionine:
(E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine + H2O ⟶ (E)-ω-(methylsulfanyl)butyl-thiohydroximate + ammonium + pyruvate
- glucosinolate biosynthesis from homomethionine:
(Z)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine + H2O ⟶ (Z)-ω-(methylsulfanyl)butyl-thiohydroximate + ammonium + pyruvate
COVID-19 Disease Map(0)
PathBank(2)
- Sulfur Metabolism (Methanesulfonate):
Hydrogen sulfide + O-Acetylserine ⟶ Acetic acid + Hydrogen Ion + L-Cysteine
- Sulfur Metabolism (Methanesulfonate):
Hydrogen sulfide + O-Acetylserine ⟶ Acetic acid + Hydrogen Ion + L-Cysteine
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Dongzhi Wang, Yongpeng Li, Haojie Wang, Yongxin Xu, Yiman Yang, Yuxin Zhou, Zhongxu Chen, Yuqing Zhou, Lixuan Gui, Yi Guo, Chunjiang Zhou, Wenqiang Tang, Shuzhi Zheng, Lei Wang, Xiulin Guo, Yingjun Zhang, Fa Cui, Xuelei Lin, Yuling Jiao, Yuehui He, Junming Li, Fei He, Xigang Liu, Jun Xiao. Boosting wheat functional genomics via an indexed EMS mutant library of KN9204.
Plant communications.
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10.1016/j.xplc.2023.100593
. [PMID: 36945776] - Hayley Whitfield, Gaye White, Colleen Sprigg, Andrew M Riley, Barry V L Potter, Andrew M Hemmings, Charles A Brearley. An ATP-responsive metabolic cassette comprised of inositol tris/tetrakisphosphate kinase 1 (ITPK1) and inositol pentakisphosphate 2-kinase (IPK1) buffers diphosphosphoinositol phosphate levels.
The Biochemical journal.
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10.1042/bcj20200423
. [PMID: 32706850] - Sophie Magréault, Julie Mankikian, Sandrine Marchand, Patrice Diot, William Couet, Thomas Flament, Nicolas Grégoire. Pharmacokinetics of colistin after nebulization or intravenous administration of colistin methanesulphonate (Colimycin®) to cystic fibrosis patients.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.
2020 05; 19(3):421-426. doi:
10.1016/j.jcf.2019.08.027
. [PMID: 31501050] - Dai Long Vu, Karolína Ranglová, Jan Hájek, Pavel Hrouzek. Quantification of methionine and selenomethionine in biological samples using multiple reaction monitoring high performance liquid chromatography tandem mass spectrometry (MRM-HPLC-MS/MS).
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2018 May; 1084(?):36-44. doi:
10.1016/j.jchromb.2018.03.012
. [PMID: 29558738] - Ali S Omrani, Wafa A Alfahad, Mohamed M Shoukri, Abeer M Baadani, Sultan Aldalbahi, Ali A Almitwazi, Ali M Albarrak. High dose intravenous colistin methanesulfonate therapy is associated with high rates of nephrotoxicity; a prospective cohort study from Saudi Arabia.
Annals of clinical microbiology and antimicrobials.
2015 Jan; 14(?):3. doi:
10.1186/s12941-015-0062-8
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Journal of hazardous materials.
2014 Jun; 274(?):181-90. doi:
10.1016/j.jhazmat.2014.03.021
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Bioorganic & medicinal chemistry letters.
2012 Mar; 22(6):2251-6. doi:
10.1016/j.bmcl.2012.01.089
. [PMID: 22342146] - Qingxin Lei, Christopher M Liebold, William L Boatright, M Shah Jahan. Distribution of stable free radicals among amino acids of isolated soy proteins.
Journal of food science.
2010 Sep; 75(7):C633-40. doi:
10.1111/j.1750-3841.2010.01746.x
. [PMID: 21535530] - Stephanie J Wallace, Jian Li, Roger L Nation, Craig R Rayner, David Taylor, Deborah Middleton, Robert W Milne, Kingsley Coulthard, John D Turnidge. Subacute toxicity of colistin methanesulfonate in rats: comparison of various intravenous dosage regimens.
Antimicrobial agents and chemotherapy.
2008 Mar; 52(3):1159-61. doi:
10.1128/aac.01101-07
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Plant physiology and biochemistry : PPB.
2007 Feb; 45(2):108-12. doi:
10.1016/j.plaphy.2007.01.011
. [PMID: 17344056] - Lawrence G Palmer, Gustavo Frindt. Cl- channels of the distal nephron.
American journal of physiology. Renal physiology.
2006 Dec; 291(6):F1157-68. doi:
10.1152/ajprenal.00496.2005
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Biochemistry.
2006 May; 45(17):5538-50. doi:
10.1021/bi060101v
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Chemico-biological interactions.
2005 May; 153-154(?):261-6. doi:
10.1016/j.cbi.2005.03.033
. [PMID: 15935825] - Dean A Martens, Kevin L Loeffelmann. Soil amino acid composition quantified by acid hydrolysis and anion chromatography-pulsed amperometry.
Journal of agricultural and food chemistry.
2003 Oct; 51(22):6521-9. doi:
10.1021/jf034422e
. [PMID: 14558773] - Kazimierz Wrobel, Katarzyna Wrobel, Sasi S Kannamkumarath, Joseph A Caruso. Identification of selenium species in urine by ion-pairing HPLC-ICP-MS using laboratory-synthesized standards.
Analytical and bioanalytical chemistry.
2003 Oct; 377(4):670-4. doi:
10.1007/s00216-003-2147-z
. [PMID: 12937882] - Suramya Waidyanatha, Melissa A Troester, Andrew B Lindstrom, Stephen M Rappaport. Measurement of hemoglobin and albumin adducts of naphthalene-1,2-oxide, 1,2-naphthoquinone and 1,4-naphthoquinone after administration of naphthalene to F344 rats.
Chemico-biological interactions.
2002 Oct; 141(3):189-210. doi:
10.1016/s0009-2797(02)00048-0
. [PMID: 12385719] - K J Angelis, M McGuffie, M Menke, I Schubert. Adaptation to alkylation damage in DNA measured by the comet assay.
Environmental and molecular mutagenesis.
2000; 36(2):146-50. doi:
10.1002/1098-2280(2000)36:2<146::aid-em9>3.0.co;2-5
. [PMID: 11013413] - S Waidyanatha, K Yeowell-O'Connell, S M Rappaport. A new assay for albumin and hemoglobin adducts of 1,2- and 1,4-benzoquinones.
Chemico-biological interactions.
1998 Sep; 115(2):117-39. doi:
10.1016/s0009-2797(98)00067-2
. [PMID: 9826945] - A M Jayawant, E R Stephenson, C M Baumgarten, R J Damiano. Prevention of cell swelling with low chloride St. Thomas' Hospital solution improves postischemic myocardial recovery.
The Journal of thoracic and cardiovascular surgery.
1998 May; 115(5):1196-202. doi:
10.1016/s0022-5223(98)70421-0
. [PMID: 9605091] - D Filipovic, H Sackin. Stretch- and volume-activated channels in isolated proximal tubule cells.
The American journal of physiology.
1992 May; 262(5 Pt 2):F857-70. doi:
10.1152/ajprenal.1992.262.5.f857
. [PMID: 1317123] - G Brambilla, E Cajelli, R Canonero, A Martelli, U M Marinari. Mutagenicity in V79 Chinese hamster cells of n-alkanals produced by lipid peroxidation.
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1989 Jul; 4(4):277-9. doi:
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. [PMID: 2550723] - A Sono, K Sakaguchi. Inhibition of protein synthesis does not antagonize induction of UV-induced sister-chromatid exchange in xeroderma pigmentosum cells.
Cell structure and function.
1988 Feb; 13(1):39-43. doi:
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The Journal of biological chemistry.
1986 Jun; 261(18):8434-41. doi:
10.1016/s0021-9258(19)83931-5
. [PMID: 3013852] - J S LAWSON, A S HEWSTONE. TOXIC EFFECTS ON COLISTIN METHANE SULPHONATE IN THE NEW-BORN.
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