D-(-)-Tagatose (BioDeep_00000837632)
Main id: BioDeep_00000014498
PANOMIX_OTCML-2023 BioNovoGene_Lab2019 natural product
代谢物信息卡片
化学式: C6H12O6 (180.0634)
中文名称: D-塔格糖
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C(C(C(C(=O)CO)O)O)O)O
InChI: InChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3,5-9,11-12H,1-2H2/t3-,5+,6-/m1/s1
描述信息
D064449 - Sequestering Agents > D002614 - Chelating Agents > D007502 - Iron Chelating Agents
同义名列表
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:47693
- KEGGdrug: D09007
- PubChem: 92092
- DrugBank: DB04936
- ChEMBL: CHEMBL1236183
- CAS: 17598-81-1
- CAS: 87-81-0
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-550
- KEGG: C00795
- PubChem: 4053
- KNApSAcK: 4249
- LOTUS: LTS0234757
分类词条
相关代谢途径
Reactome(0)
PlantCyc(0)
代谢反应
1 个相关的代谢反应过程信息。
Reactome(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
13 个相关的物种来源信息
- 2759 - Eukaryota: LTS0234757
- 4136 - Lamiaceae: LTS0234757
- 3398 - Magnoliopsida: LTS0234757
- 21861 - Pogostemon: LTS0234757
- 28511 - Pogostemon cablin: 10.1021/JF304466T
- 28511 - Pogostemon cablin: LTS0234757
- 4070 - Solanaceae: LTS0234757
- 4107 - Solanum: LTS0234757
- 4081 - Solanum lycopersicum: 10.1038/SDATA.2014.29
- 4081 - Solanum lycopersicum: LTS0234757
- 35493 - Streptophyta: LTS0234757
- 58023 - Tracheophyta: LTS0234757
- 33090 - Viridiplantae: LTS0234757
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Verónica Sambra, Isabella A Vicuña, Kathleen M Priken, Selva L Luna, Daniela A Allendes, Paula M Godoy, Victoria Novik, Claudia A Vega. Acute responses of stevia and d-tagatose intake on metabolic parameters and appetite/satiety in insulin resistance.
Clinical nutrition ESPEN.
2022 06; 49(?):217-224. doi:
10.1016/j.clnesp.2022.04.018
. [PMID: 35623816] - Michael J Haas, Shrina Parekh, Poonam Kalidas, Angela Richter, Firas Warda, Norman C W Wong, Masaaki Tokuda, Arshag D Mooradian. Insulin mimetic effect of D-allulose on apolipoprotein A-I gene.
Journal of food biochemistry.
2022 02; 46(2):e14064. doi:
10.1111/jfbc.14064
. [PMID: 34984676] - Paola Elisa Corneo, Andrea Nesler, Cesare Lotti, Abdessalem Chahed, Urska Vrhovsek, Ilaria Pertot, Michele Perazzolli. Interactions of tagatose with the sugar metabolism are responsible for Phytophthora infestans growth inhibition.
Microbiological research.
2021 Jun; 247(?):126724. doi:
10.1016/j.micres.2021.126724
. [PMID: 33640575] - Susumu Mochizuki, Takeshi Fukumoto, Toshiaki Ohara, Kouhei Ohtani, Akihide Yoshihara, Yoshio Shigematsu, Keiji Tanaka, Koichi Ebihara, Shigeyuki Tajima, Kenji Gomi, Kazuya Ichimura, Ken Izumori, Kazuya Akimitsu. The rare sugar D-tagatose protects plants from downy mildews and is a safe fungicidal agrochemical.
Communications biology.
2020 08; 3(1):423. doi:
10.1038/s42003-020-01133-7
. [PMID: 32759958] - Michele Perazzolli, Andrea Nesler, Oscar Giovannini, Livio Antonielli, Gerardo Puopolo, Ilaria Pertot. Ecological impact of a rare sugar on grapevine phyllosphere microbial communities.
Microbiological research.
2020 Feb; 232(?):126387. doi:
10.1016/j.micres.2019.126387
. [PMID: 31790975] - Yu-Xuan Liang, Peng Wen, Yu Wang, Dong-Mei OuYang, Da Wang, Yu-Zhong Chen, Ya Song, Jie Deng, Yuan-Ming Sun, Hong Wang. The Constipation-Relieving Property of d-Tagatose by Modulating the Composition of Gut Microbiota.
International journal of molecular sciences.
2019 Nov; 20(22):. doi:
10.3390/ijms20225721
. [PMID: 31739640] - S J Son, J H Koh, M R Park, S Ryu, W J Lee, B Yun, J-H Lee, S Oh, Y Kim. Effect of the Lactobacillus rhamnosus strain GG and tagatose as a synbiotic combination in a dextran sulfate sodium-induced colitis murine model.
Journal of dairy science.
2019 Apr; 102(4):2844-2853. doi:
10.3168/jds.2018-15013
. [PMID: 30799108] - Yasuo Nagata, Narumi Mizuta, Akane Kanasaki, Kazunari Tanaka. Rare sugars, d-allulose, d-tagatose and d-sorbose, differently modulate lipid metabolism in rats.
Journal of the science of food and agriculture.
2018 Mar; 98(5):2020-2026. doi:
10.1002/jsfa.8687
. [PMID: 28940418] - Dhananjay Yadav, Suk-Jeong Kim, Myung Ae Bae, Jae-Ryong Kim, Kyung-Hyun Cho. The Ability of Different Ketohexoses to Alter Apo-A-I Structure and Function In Vitro and to Induce Hepatosteatosis, Oxidative Stress, and Impaired Plasma Lipid Profile in Hyperlipidemic Zebrafish.
Oxidative medicine and cellular longevity.
2018; 2018(?):3124364. doi:
10.1155/2018/3124364
. [PMID: 29951163] - Debora Collotta, Laura Lucarini, Fausto Chiazza, Alessia Sofia Cento, Mariaconcetta Durante, Silvia Sgambellone, Jacopo Chini, Francesca Baratta, Manuela Aragno, Raffaella Mastrocola, Emanuela Masini, Massimo Collino. Reduced Susceptibility to Sugar-Induced Metabolic Derangements and Impairments of Myocardial Redox Signaling in Mice Chronically Fed with D-Tagatose when Compared to Fructose.
Oxidative medicine and cellular longevity.
2018; 2018(?):5042428. doi:
10.1155/2018/5042428
. [PMID: 30327714] - Jung Hyun Kwak, Min Sun Kim, Jin Hee Lee, Yoon Jung Yang, Ki Ho Lee, Oh Yoen Kim, Jong Ho Lee. Beneficial effect of tagatose consumption on postprandial hyperglycemia in Koreans: a double-blind crossover designed study.
Food & function.
2013 Aug; 4(8):1223-8. doi:
10.1039/c3fo00006k
. [PMID: 23760573] - Tongzhi Wu, Beiyi R Zhao, Michelle J Bound, Helen L Checklin, Max Bellon, Tanya J Little, Richard L Young, Karen L Jones, Michael Horowitz, Christopher K Rayner. Effects of different sweet preloads on incretin hormone secretion, gastric emptying, and postprandial glycemia in healthy humans.
The American journal of clinical nutrition.
2012 Jan; 95(1):78-83. doi:
10.3945/ajcn.111.021543
. [PMID: 22158727] - Thomas W Donner, Laurence S Magder, Kiarash Zarbalian. Dietary supplementation with d-tagatose in subjects with type 2 diabetes leads to weight loss and raises high-density lipoprotein cholesterol.
Nutrition research (New York, N.Y.).
2010 Dec; 30(12):801-6. doi:
10.1016/j.nutres.2010.09.007
. [PMID: 21147362] - Sara B Police, J Clay Harris, Robert A Lodder, Lisa A Cassis. Effect of diets containing sucrose vs. D-tagatose in hypercholesterolemic mice.
Obesity (Silver Spring, Md.).
2009 Feb; 17(2):269-75. doi:
10.1038/oby.2008.508
. [PMID: 19008872] - L Normén, H N Laerke, B B Jensen, A M Langkilde, H Andersson. Small-bowel absorption of D-tagatose and related effects on carbohydrate digestibility: an ileostomy study.
The American journal of clinical nutrition.
2001 Jan; 73(1):105-10. doi:
10.1093/ajcn/73.1.105
. [PMID: 11124758] - B Buemann, H Gesmar, A Astrup, B Quistorff. Effects of oral D-tagatose, a stereoisomer of D-fructose, on liver metabolism in man as examined by 31P-magnetic resonance spectroscopy.
Metabolism: clinical and experimental.
2000 Oct; 49(10):1335-9. doi:
10.1053/meta.2000.9532
. [PMID: 11079825] - B Buemann, S Toubro, J J Holst, J F Rehfeld, B M Bibby, A Astrup. D-tagatose, a stereoisomer of D-fructose, increases blood uric acid concentration.
Metabolism: clinical and experimental.
2000 Aug; 49(8):969-76. doi:
10.1053/meta.2000.7724
. [PMID: 10954012] - H N Laerke, B B Jensen, S Højsgaard. In vitro fermentation pattern of D-tagatose is affected by adaptation of the microbiota from the gastrointestinal tract of pigs.
The Journal of nutrition.
2000 Jul; 130(7):1772-9. doi:
10.1093/jn/130.7.1772
. [PMID: 10867049] - T W Donner, J F Wilber, D Ostrowski. D-tagatose, a novel hexose: acute effects on carbohydrate tolerance in subjects with and without type 2 diabetes.
Diabetes, obesity & metabolism.
1999 Sep; 1(5):285-91. doi:
10.1046/j.1463-1326.1999.00039.x
. [PMID: 11225640] - A Bär, B A Lina, D M de Groot, B de Bie, M J Appel. Effect of D-tagatose on liver weight and glycogen content of rats.
Regulatory toxicology and pharmacology : RTP.
1999 Apr; 29(2 Pt 2):S11-28. doi:
10.1006/rtph.1998.1266
. [PMID: 10341157] - J P Saunders, T W Donner, J H Sadler, G V Levin, N G Makris. Effects of acute and repeated oral doses of D-tagatose on plasma uric acid in normal and diabetic humans.
Regulatory toxicology and pharmacology : RTP.
1999 Apr; 29(2 Pt 2):S57-65. doi:
10.1006/rtph.1998.1264
. [PMID: 10341162] - J P Saunders, L R Zehner, G V Levin. Disposition of D-[U-14C]tagatose in the rat.
Regulatory toxicology and pharmacology : RTP.
1999 Apr; 29(2 Pt 2):S46-56. doi:
10.1006/rtph.1998.1251
. [PMID: 10341161] - A Lee, D M Storey. Comparative gastrointestinal tolerance of sucrose, lactitol, or D-tagatose in chocolate.
Regulatory toxicology and pharmacology : RTP.
1999 Apr; 29(2 Pt 2):S78-82. doi:
10.1006/rtph.1998.1255
. [PMID: 10341165] - B Buemann, S Toubro, A Astrup. D-Tagatose, a stereoisomer of D-fructose, increases hydrogen production in humans without affecting 24-hour energy expenditure or respiratory exchange ratio.
The Journal of nutrition.
1998 Sep; 128(9):1481-6. doi:
10.1093/jn/128.9.1481
. [PMID: 9732308] - J C Paterna, F Boess, A Stäubli, U A Boelsterli. Antioxidant and cytoprotective properties of D-tagatose in cultured murine hepatocytes.
Toxicology and applied pharmacology.
1998 Jan; 148(1):117-25. doi:
10.1006/taap.1997.8315
. [PMID: 9465271] - G Livesey, J C Brown. D-tagatose is a bulk sweetener with zero energy determined in rats.
The Journal of nutrition.
1996 Jun; 126(6):1601-9. doi:
10.1093/jn/126.6.1601
. [PMID: 8648434]