sodium glycocholate (BioDeep_00000829749)

   

PANOMIX_OTCML-2023 Bile acids


代谢物信息卡片


sodium glycocholate

化学式: C26H42NNaO6 (487.29096720000007)
中文名称: 甘氨胆酸钠
谱图信息: 最多检出来源 Homo sapiens(bile_acids) 10%

Reviewed

Last reviewed on 2024-08-07.

Cite this Page

sodium glycocholate. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/sodium_glycocholate (retrieved 2024-09-20) (BioDeep RN: BioDeep_00000829749). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CC(CCC(=O)NCC(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C.[Na+]
InChI: /q

描述信息

D005765 - Gastrointestinal Agents > D002756 - Cholagogues and Choleretics
D005765 - Gastrointestinal Agents > D001647 - Bile Acids and Salts
D005765 - Gastrointestinal Agents > D002793 - Cholic Acids
D013501 - Surface-Active Agents > D003902 - Detergents
Glycocholic acid sodium is an orally active bile acid with anticancer activity, targeting against pump resistance-related and non-pump resistance-related pathways[1].
Glycocholic acid sodium is an orally active bile acid with anticancer activity, targeting against pump resistance-related and non-pump resistance-related pathways[1].

同义名列表

2 个代谢物同义名

sodium glycocholate; Glycocholic acid (sodium)



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Hamid Alghurabi, Huda Jassim Muhammad, Tatsuaki Tagami, Koki Ogawa, Tetsuya Ozeki. Optimization, cellular uptake, and in vivo evaluation of Eudragit S100-coated bile salt-containing liposomes for oral colonic delivery of 5-aminosalicylic acid. International journal of pharmaceutics. 2023 Dec; 648(?):123597. doi: 10.1016/j.ijpharm.2023.123597. [PMID: 37952559]
  • Yu Tang, Zhu Han, Han Zhang, Li Che, Genjie Liao, Jun Peng, Yu Lin, Yi Wang. Characterization of Calculus bovis by principal component analysis assisted qHNMR profiling to distinguish nefarious frauds. Journal of pharmaceutical and biomedical analysis. 2023 Mar; 228(?):115320. doi: 10.1016/j.jpba.2023.115320. [PMID: 36871364]
  • Shibin Yao, Shengjie Ren, Chunfang Cai, Xiamin Cao, Ye Shi, Ping Wu, Yuantu Ye. Glycocholic acid supplementation improved growth performance and alleviated tissue damage in the liver and intestine in Pelteobagrus fulvidraco fed a high-pectin diet. Fish physiology and biochemistry. 2022 Dec; ?(?):. doi: 10.1007/s10695-022-01148-3. [PMID: 36454392]
  • Xiaolu Zhou, Yaling Li, Ren Mu, Chuanming Wang, Yuyan Song, Caibi Zhou, Xin Mei. Duyun compound green tea extracts regulate bile acid metabolism on mice induced by high-fat diet. The British journal of nutrition. 2022 Oct; ?(?):1-9. doi: 10.1017/s0007114522003166. [PMID: 36210537]
  • Jian Wu, Yanping Xu, Yubao Cui, Mariza Bortolanza, Minjie Wang, Bin Jiang, Meina Yan, Wei Liang, Yiwen Yao, Qiaoling Pan, Jinfeng Yang, Jiong Yu, Dawei Wang, Hongcui Cao, Lanjuan Li. Dynamic changes of serum metabolites associated with infection and severity of patients with acute hepatitis E infection. Journal of medical virology. 2022 06; 94(6):2714-2726. doi: 10.1002/jmv.27669. [PMID: 35199373]
  • Feiyang Deng, You Han Bae. Lipid raft-mediated and upregulated coordination pathways assist transport of glycocholic acid-modified nanoparticle in a human breast cancer cell line of SK-BR-3. International journal of pharmaceutics. 2022 Apr; 617(?):121589. doi: 10.1016/j.ijpharm.2022.121589. [PMID: 35176336]
  • Hongxue Liu, Haidong Wang, Muling Zhang. Deep Learning Algorithm-Based Magnetic Resonance Imaging Feature-Guided Serum Bile Acid Profile and Perinatal Outcomes in Intrahepatic Cholestasis of Pregnancy. Computational and mathematical methods in medicine. 2022; 2022(?):8081673. doi: 10.1155/2022/8081673. [PMID: 35707042]
  • Michelle L Manni, Victoria A Heinrich, Gregory J Buchan, James P O'Brien, Crystal Uvalle, Veronika Cechova, Adolf Koudelka, Dharti Ukani, Mohamad Rawas-Qalaji, Tim D Oury, Renee Hart, Madeline Ellgass, Steven J Mullett, Merritt L Fajt, Sally E Wenzel, Fernando Holguin, Bruce A Freeman, Stacy G Wendell. Nitroalkene fatty acids modulate bile acid metabolism and lung function in obese asthma. Scientific reports. 2021 09; 11(1):17788. doi: 10.1038/s41598-021-96471-9. [PMID: 34493738]
  • Xiping Cui, Qiyi He, Huiyi Yang, Yingshan Chen, Ding Shen, Sergei A Eremin, Yunping Mu, Suqing Zhao. Development of enzyme-free single-step immunoassays for glycocholic acid based on palladium nanoparticle-mediated signal generation. Analytical and bioanalytical chemistry. 2021 Sep; 413(23):5733-5742. doi: 10.1007/s00216-021-03548-5. [PMID: 34476526]
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  • José Tadeu Stefano, Laura Vilar Guedes, Arthur Alencar Arrais de Souza, Denise Siqueira Vanni, Venâncio Avancini Ferreira Alves, Flair José Carrilho, Alvaro Largura, Marco Arrese, Claudia P Oliveira. Usefulness of collagen type IV in the detection of significant liver fibrosis in nonalcoholic fatty liver disease. Annals of hepatology. 2021 Jan; 20(?):100253. doi: 10.1016/j.aohep.2020.08.070. [PMID: 32949785]
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  • Issey Takehara, Nobuaki Watanabe, Daiki Mori, Osamu Ando, Hiroyuki Kusuhara. Effect of Rifampicin on the Plasma Concentrations of Bile Acid-O-Sulfates in Monkeys and Human Liver-Transplanted Chimeric Mice With or Without Bile Flow Diversion. Journal of pharmaceutical sciences. 2019 08; 108(8):2756-2764. doi: 10.1016/j.xphs.2019.03.021. [PMID: 30905707]
  • Alvaro Alonso, Bing Yu, Yan V Sun, Lin Y Chen, Laura R Loehr, Wesley T O'Neal, Elsayed Z Soliman, Eric Boerwinkle. Serum Metabolomics and Incidence of Atrial Fibrillation (from the Atherosclerosis Risk in Communities Study). The American journal of cardiology. 2019 06; 123(12):1955-1961. doi: 10.1016/j.amjcard.2019.03.017. [PMID: 30979411]
  • Qiangyuan Fan, Yongtai Zhang, Xuefeng Hou, Zhe Li, Kai Zhang, Qun Shao, Nianping Feng. Improved oral bioavailability of notoginsenoside R1 with sodium glycocholate-mediated liposomes: Preparation by supercritical fluid technology and evaluation in vitro and in vivo. International journal of pharmaceutics. 2018 Dec; 552(1-2):360-370. doi: 10.1016/j.ijpharm.2018.10.005. [PMID: 30292894]
  • Qiyi He, Xiping Cui, Ding Shen, Yingshan Chen, Zhengyun Jiang, Rui Lv, Sergei A Eremin, Suqing Zhao. Development of a simple, rapid and high-throughput fluorescence polarization immunoassay for glycocholic acid in human urine. Journal of pharmaceutical and biomedical analysis. 2018 Sep; 158(?):431-437. doi: 10.1016/j.jpba.2018.06.023. [PMID: 29945060]
  • Xiping Cui, Natalia Vasylieva, Ding Shen, Bogdan Barnych, Jun Yang, Qiyi He, Zhengyun Jiang, Suqing Zhao, Bruce D Hammock. Biotinylated single-chain variable fragment-based enzyme-linked immunosorbent assay for glycocholic acid. The Analyst. 2018 Apr; 143(9):2057-2065. doi: 10.1039/c7an02024d. [PMID: 29629470]
  • Cheng Guo, Cong Xie, Peili Ding, Guangming Qin, Weimin Mo, Xiaoji Cao, Shu Zheng. Quantification of glycocholic acid in human serum by stable isotope dilution ultra performance liquid chromatography electrospray ionization tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2018 Jan; 1072(?):315-319. doi: 10.1016/j.jchromb.2017.11.037. [PMID: 29202363]
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