4-Methylumbelliferyl glucoside (BioDeep_00000759356)

   


代谢物信息卡片


4-methylumbelliferyl β-D-glucoside

化学式: C16H18O8 (338.1001628)
中文名称: 4-甲基伞形酮-β-D-葡糖苷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)OC3C(C(C(C(O3)CO)O)O)O
InChI: InChI=1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15-,16-/m1/s1

描述信息

同义名列表

2 个代谢物同义名

4-methylumbelliferyl β-D-glucoside; 4-Methylumbelliferyl glucoside



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

1 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(1)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jeroen van Smeden, Irini M Dijkhoff, Richard W J Helder, Hanin Al-Khakany, Daphne E C Boer, Anne Schreuder, Wouter W Kallemeijn, Samira Absalah, Herman S Overkleeft, Johannes M F G Aerts, Joke A Bouwstra. In situ visualization of glucocerebrosidase in human skin tissue: zymography versus activity-based probe labeling. Journal of lipid research. 2017 12; 58(12):2299-2309. doi: 10.1194/jlr.m079376. [PMID: 29025868]
  • Xuefeng Cao, Wenpeng Zhang, Xu Yan, Zhi Huang, Zhenqing Zhang, Peng Wang, Jie Shen. Modification on the O-glucoside of Sergliflozin-A: A new strategy for SGLT2 inhibitor design. Bioorganic & medicinal chemistry letters. 2016 May; 26(9):2170-3. doi: 10.1016/j.bmcl.2016.03.065. [PMID: 27025345]
  • Cécile Ouairy, Thierry Cresteil, Bernard Delpech, David Crich. Synthesis and evaluation of 3-deoxy and 3-deoxy-3-fluoro derivatives of gluco- and manno-configured tetrahydropyridoimidazole glycosidase inhibitors. Carbohydrate research. 2013 Aug; 377(?):35-43. doi: 10.1016/j.carres.2013.05.011. [PMID: 23792222]
  • Young Ock Ahn, Bun-ichi Shimizu, Kanzo Sakata, Dashzeveg Gantulga, Changhe Zhou, Zhanghe Zhou, David R Bevan, Asim Esen. Scopolin-hydrolyzing beta-glucosidases in roots of Arabidopsis. Plant & cell physiology. 2010 Jan; 51(1):132-43. doi: 10.1093/pcp/pcp174. [PMID: 19965874]
  • Yasuhiro Hayashi, Kouta Zama, Eriko Abe, Nozomu Okino, Takehiko Inoue, Kousaku Ohno, Makoto Ito. A sensitive and reproducible fluorescent-based HPLC assay to measure the activity of acid as well as neutral beta-glucocerebrosidases. Analytical biochemistry. 2008 Dec; 383(1):122-9. doi: 10.1016/j.ab.2008.07.024. [PMID: 18708024]
  • Dumrongkiet Arthan, Prasat Kittakoop, Asim Esen, Jisnuson Svasti. Furostanol glycoside 26-O-beta-glucosidase from the leaves of Solanum torvum. Phytochemistry. 2006 Jan; 67(1):27-33. doi: 10.1016/j.phytochem.2005.09.035. [PMID: 16289258]
  • Shu Wei, Ben-Ami Bravdo, Oded Shoseyov. Fluorescent screening of transgenic Arabidopsis seeds without germination. Plant physiology. 2004 Jun; 135(2):709-14. doi: 10.1104/pp.104.040709. [PMID: 15208418]
  • B Hendel, J Marxsen, D Fiebig, G Preuss. Extracellular enzyme activities during slow sand filtration in a water recharge plant. Water research. 2001 Jul; 35(10):2484-8. doi: 10.1016/s0043-1354(00)00538-8. [PMID: 11394783]
  • M Mikhaylova, G Wiederschain, V Mikhaylov, J M Aerts. The enzymatic hydrolysis of 6-acylamino-4-methylumbelliferyl-beta-D-glucosides: identification of a novel human acid beta-glucosidase. Biochimica et biophysica acta. 1996 Oct; 1317(1):71-9. doi: 10.1016/0925-4439(96)00040-3. [PMID: 8876629]
  • L Jackson, B E Langlois, K A Dawson. Beta-glucuronidase activities of fecal isolates from healthy swine. Journal of clinical microbiology. 1992 Aug; 30(8):2113-7. doi: 10.1128/jcm.30.8.2113-2117.1992. [PMID: 1500519]
  • W M Holleran, Y Takagi, G Imokawa, S Jackson, J M Lee, P M Elias. beta-Glucocerebrosidase activity in murine epidermis: characterization and localization in relation to differentiation. Journal of lipid research. 1992 Aug; 33(8):1201-9. doi: 10.1016/s0022-2275(20)40772-2. [PMID: 1431599]
  • J M Aerts, W E Donker-Koopman, M Koot, J A Barranger, J M Tager, A W Schram. Deficient activity of glucocerebrosidase in urine from patients with type 1 Gaucher disease. Clinica chimica acta; international journal of clinical chemistry. 1986 Jul; 158(2):155-63. doi: 10.1016/0009-8981(86)90231-7. [PMID: 2943536]
  • A J Cutler, F Constabel, W G Kurz, P D Shargool. Quantitation of the delivery of liposome contents into plant protoplasts. Analytical biochemistry. 1984 Jun; 139(2):482-6. doi: 10.1016/0003-2697(84)90038-1. [PMID: 6476383]
  • S L Berent, N S Radin. Mechanism of activation of glucocerebrosidase by co-beta-glucosidase (glucosidase activator protein). Biochimica et biophysica acta. 1981 Jun; 664(3):572-82. doi: 10.1016/0005-2760(81)90134-x. [PMID: 6268176]
  • S S Raghavan, J Topol, E H Kolodny. Leukocyte beta-glucosidase in homozygotes and heterozygotes for Gaucher disease. American journal of human genetics. 1980 Mar; 32(2):158-73. doi: . [PMID: 6770675]
  • D M Broadhead, J Butterworth. Pompe's disease: diagnosis in kidney and leucocytes using 4-methylumbelliferyl-alpha-D-glucopyranoside. Clinical genetics. 1978 Jun; 13(6):504-10. doi: 10.1111/j.1399-0004.1978.tb01206.x. [PMID: 352582]