cabraleadiol (BioDeep_00000742750)
代谢物信息卡片
(20S,24S)-20,24-Epoxydammarane-3beta,25-diol
化学式: C30H52O3 (460.3916242)
中文名称: 南美楝属二醇, 3-表南美楝属二醇
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1(C2CCC3(C(C2(CCC1O)C)CCC4C3(CCC4C5(CCC(O5)C(C)(C)O)C)C)C)C
InChI: InChI=1S/C30H52O3/c1-25(2)21-12-17-29(7)22(27(21,5)15-13-23(25)31)10-9-19-20(11-16-28(19,29)6)30(8)18-14-24(33-30)26(3,4)32/h19-24,31-32H,9-18H2,1-8H3
描述信息
A tetracyclic triterpenoid isolated from Aglaia abbreviata.
同义名列表
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:70272
- PubChem: 21625899
- PubChem: 3850493
- ChEMBL: CHEMBL3109461
- CAS: 67253-01-4
- CAS: 19942-04-2
- MetaboLights: MTBLC70272
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Sufang Peng, Xiaobo Li, Weiwei Jiang, Yina Wang, Guisheng Xiang, Menghan Li, Yuanyuan Wang, Zijiang Yang, Ying Li, Xiangyu Liu, Guanghui Zhang, Chunhua Ma, Shengchao Yang. Identification of two key UDP-glycosyltransferases responsible for the ocotillol-type ginsenoside majonside-R2 biosynthesis in Panax vietnamensis var. fuscidiscus.
Planta.
2023 May; 257(6):119. doi:
10.1007/s00425-023-04143-x. [PMID: 37178342] - Zijiang Yang, Xiaobo Li, Ling Yang, Sufang Peng, Wanling Song, Yuan Lin, Guisheng Xiang, Ying Li, Shuang Ye, Chunhua Ma, Jianhua Miao, Guanghui Zhang, Wei Chen, Shengchao Yang, Yang Dong. Comparative genomics reveals the diversification of triterpenoid biosynthesis and origin of ocotillol-type triterpenes in Panax.
Plant communications.
2023 Mar; ?(?):100591. doi:
10.1016/j.xplc.2023.100591. [PMID: 36926697] - Ana Beatriz Morales-Cepeda, Luis Alejandro Macclesh Del Pino-Pérez, Mireya Marmolejo, José Luis Rivera-Armenta, Hernan Peraza-Vázquez. Isolation of ocotillol/ocotillone from Fouquieria splendens (Ocote) using a batch reactor.
Preparative biochemistry & biotechnology.
2022; 52(5):540-548. doi:
10.1080/10826068.2021.1972425. [PMID: 34657566] - Xue-Ni Niu, Wen Luo, Chong-Ning Lv, Jin-Cai Lu. Research progress on naturally-occurring and semi-synthetic ocotillol-type ginsenosides in the genus Panax L. (Araliaceae).
Chinese journal of natural medicines.
2021 Sep; 19(9):648-655. doi:
10.1016/s1875-5364(21)60089-4. [PMID: 34561075] - Ying Zhang, Hui Yu, Shuzheng Fu, Luying Tan, Junli Liu, Baisong Zhou, Le Li, Yunhe Liu, Caixia Wang, Pingya Li, Jinping Liu. Synthesis and Anti-Hepatocarcinoma Effect of Amino Acid Derivatives of Pyxinol and Ocotillol.
Molecules (Basel, Switzerland).
2021 Feb; 26(4):. doi:
10.3390/molecules26040780. [PMID: 33546225] - Zeng Qi, Zhenzhou Wang, Baisong Zhou, Shuilian Fu, Tie Hong, Pingya Li, Jinping Liu. A new ocotillol-type ginsenoside from stems and leaves of Panax quinquefolium L. and its anti-oxidative effect on hydrogen peroxide exposed A549 cells.
Natural product research.
2020 Sep; 34(17):2474-2481. doi:
10.1080/14786419.2018.1543677. [PMID: 30602312] - Ziyi Zhang, Zhiguo Chen, Shengyu Zhang, Xiao Shao, Zhiwen Zhou. Antibacterial activity of the structurally novel ocotillol-type lactone and its analogues.
Fitoterapia.
2020 Jul; 144(?):104597. doi:
10.1016/j.fitote.2020.104597. [PMID: 32325155] - Cuizhu Wang, Yuze Yuan, He Pan, Alan Chen-Yu Hsu, Jinluan Chen, Jinping Liu, Pingya Li, Fang Wang. Protective Effect of Ocotillol, the Derivate of Ocotillol-Type Saponins in Panax Genus, against Acetic Acid-Induced Gastric Ulcer in Rats Based on Untargeted Metabolomics.
International journal of molecular sciences.
2020 Apr; 21(7):. doi:
10.3390/ijms21072577. [PMID: 32276345] - Jianqiang Zhang, Qian Zhang, Yangrong Xu, Huixiang Li, Fenglan Zhao, Chaoming Wang, Zhi Liu, Pan Liu, Yanan Liu, Qingguo Meng, Feng Zhao. Synthesis and In Vitro Anti-inflammatory Activity of C20 Epimeric Ocotillol-Type Triterpenes and Protopanaxadiol.
Planta medica.
2019 Mar; 85(4):292-301. doi:
10.1055/a-0770-0994. [PMID: 30380571] - Yuzhong Li, Hong Hu, Zhenguo Li, Ruihua Li, Fang Xu, Chengyan Zhao, Yue An, Yonge Liu, Zhongli Wang, Binbin Zhang, Cong Geng. Pharmacokinetic Characterizations of Ginsenoside Ocotillol, RT5 and F11, the Promising Agents for Alzheimer's Disease from American Ginseng, in Rats and Beagle Dogs.
Pharmacology.
2019; 104(1-2):7-20. doi:
10.1159/000499595. [PMID: 30947229] - Yi Bi, Xian-Xuan Liu, Heng-Yuan Zhang, Xiao Yang, Ze-Yun Liu, Jing Lu, Peter John Lewis, Chong-Zhi Wang, Jin-Yi Xu, Qing-Guo Meng, Cong Ma, Chun-Su Yuan. Synthesis and Antibacterial Evaluation of Novel 3-Substituted Ocotillol-Type Derivatives as Leads.
Molecules (Basel, Switzerland).
2017 Apr; 22(4):. doi:
10.3390/molecules22040590. [PMID: 28387737] - Jin-Ju Jeong, Thi Hong Van Le, Sang-Yun Lee, Su-Hyeon Eun, Minh Duc Nguyen, Jeong Hill Park, Dong-Hyun Kim. Anti-inflammatory effects of vina-ginsenoside R2 and majonoside R2 isolated from Panax vietnamensis and their metabolites in lipopolysaccharide-stimulated macrophages.
International immunopharmacology.
2015 Sep; 28(1):700-6. doi:
10.1016/j.intimp.2015.07.025. [PMID: 26256699] - Wenyan Wang, Li Wang, Xiangmeng Wu, Lixiao Xu, Qingguo Meng, Wanhui Liu. Stereoselective formation and metabolism of 20(S)-protopanaxadiol ocotillol type epimers in vivo and in vitro.
Chirality.
2015 Feb; 27(2):170-6. doi:
10.1002/chir.22407. [PMID: 25422175] - Thi Hong Van Le, Gwang Jin Lee, Huynh Kim Long Vu, Sung Won Kwon, Ngoc Khoi Nguyen, Jeong Hill Park, Minh Duc Nguyen. Ginseng Saponins in Different Parts of Panax vietnamensis.
Chemical & pharmaceutical bulletin.
2015; 63(11):950-4. doi:
10.1248/cpb.c15-00369. [PMID: 26521860] - Yi Bi, Cong Ma, Hengyuan Zhang, Zhiwen Zhou, Jian Yang, Zhenlei Zhang, Qingguo Meng, Peter J Lewis, Jinyi Xu. Novel 3-substituted ocotillol-type triterpenoid derivatives as antibacterial candidates.
Chemical biology & drug design.
2014 Oct; 84(4):489-96. doi:
10.1111/cbdd.12337. [PMID: 24811479] - Hui-Jiao Yan, Jun-Song Wang, Ling-Yi Kong. Cytotoxic dammarane-type triterpenoids from the stem bark of Dysoxylum binecteriferum.
Journal of natural products.
2014 Feb; 77(2):234-42. doi:
10.1021/np400700g. [PMID: 24547740] - Xiaoya Fu, Liang Kong, Mingtan Tang, Jianqiao Zhang, Xueying Zhou, Gang Li, Hongbo Wang, Fenghua Fu. Protective effect of ocotillol against doxorubicin‑induced acute and chronic cardiac injury.
Molecular medicine reports.
2014 Jan; 9(1):360-4. doi:
10.3892/mmr.2013.1791. [PMID: 24220651] - Liu Han, Mei-Yu Lin, Qian Zheng, Hai-Yu Liu, Hai-Yan Liu, Gang Dong, Jin-Ping Liu, Ping-Ya Li. A new epimer of ocotillol from stems and leaves of American ginseng.
Natural product research.
2014; 28(13):935-9. doi:
10.1080/14786419.2014.896008. [PMID: 24730645] - Zhiwen Zhou, Cong Ma, Hengyuan Zhang, Yi Bi, Xia Chen, Hua Tian, Xiaoni Xie, Qingguo Meng, Peter John Lewis, Jinyi Xu. Synthesis and biological evaluation of novel ocotillol-type triterpenoid derivatives as antibacterial agents.
European journal of medicinal chemistry.
2013 Oct; 68(?):444-53. doi:
10.1016/j.ejmech.2013.07.041. [PMID: 23994872] - Wenyan Wang, Yufeng Shao, Shasha Ma, Xiangmeng Wu, Qingguo Meng. Determination of 20(S)-protopanaxadiol ocotillol type epimers in rat plasma by liquid chromatography tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2012 Mar; 887-888(?):19-24. doi:
10.1016/j.jchromb.2011.12.032. [PMID: 22305018]