styrene glycol (BioDeep_00000697578)

   

PANOMIX_OTCML-2023


代谢物信息卡片


(S)-(+)-1-Phenyl-1,2-ethanediol

化学式: C8H10O2 (138.0681)
中文名称: (±)-1-苯基-1,2-乙二醇, 1-苯基-1,2-乙二醇, (S)-1-苯基-1,2-乙二醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)C(CO)O
InChI: InChI=1S/C8H10O2/c9-6-8(10)7-4-2-1-3-5-7/h1-5,8-10H,6H2

描述信息

1-Phenylethane-1,2-diol is a typical benzyl diol compound. 1-Phenylethane-1,2-diol can be oxidized to hydroxyl ketone (2-hydroxy-1-phenylethan-1-one) selectively with variety of catalysts, including organocatalysts, metal complexes, non-noble metal oxides, bimetallics[1].
1-Phenylethane-1,2-diol is a typical benzyl diol compound. 1-Phenylethane-1,2-diol can be oxidized to hydroxyl ketone (2-hydroxy-1-phenylethan-1-one) selectively with variety of catalysts, including organocatalysts, metal complexes, non-noble metal oxides, bimetallics[1].

同义名列表

5 个代谢物同义名

1-phenyl-1,2-ethanediol; styrene glycol; (S)-(+)-1-Phenyl-1,2-ethanediol; 1-Phenylethane-1,2-diol; 1-Phenyl-1,2-ethanediol



数据库引用编号

8 个数据库交叉引用编号

分类词条

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代谢反应

0 个相关的代谢反应过程信息。

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在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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亚细胞结构定位 关联基因列表


文献列表

  • Rui Wang, Die Hu, Xuncheng Zong, Jinping Li, Lei Ding, Minchen Wu, Jianfang Li. Enantioconvergent hydrolysis of racemic styrene oxide at high concentration by a pair of novel epoxide hydrolases into (R)-phenyl-1,2-ethanediol. Biotechnology letters. 2017 Dec; 39(12):1917-1923. doi: 10.1007/s10529-017-2433-z. [PMID: 28875350]
  • Iness Bettaieb, Soumaya Bourgou, Jezia Sriti, Kamel Msaada, Ferid Limam, Brahim Marzouk. Essential oils and fatty acids composition of Tunisian and Indian cumin (Cuminum cyminum L.) seeds: a comparative study. Journal of the science of food and agriculture. 2011 Aug; 91(11):2100-7. doi: 10.1002/jsfa.4513. [PMID: 21681765]
  • Yan Xia, Samuel Chackalamannil, William J Greenlee, Charles Jayne, Bernard Neustadt, Andrew Stamford, Henry Vaccaro, Xiaoying Lucy Xu, Hana Baker, Kim O'Neill, Morgan Woods, Brian Hawes, Tim Kowalski. Discovery of a nortropanol derivative as a potent and orally active GPR119 agonist for type 2 diabetes. Bioorganic & medicinal chemistry letters. 2011 Jun; 21(11):3290-6. doi: 10.1016/j.bmcl.2011.04.035. [PMID: 21536438]
  • Iness Bettaieb, Sana Knioua, Ibtissem Hamrouni, Ferid Limam, Brahim Marzouk. Water-deficit impact on fatty acid and essential oil composition and antioxidant activities of cumin (Cuminum cyminum L.) aerial parts. Journal of agricultural and food chemistry. 2011 Jan; 59(1):328-34. doi: 10.1021/jf1037618. [PMID: 21141890]
  • Wan-Qiu Yang, Xiang-Dong Qin, Hong-Jun Shao, Li-Zhen Fang, Fei Wang, Zhi-Hui Ding, Ze-Jun Dong, Ji-Kai Liu. New phenyl-ethanediols from the culture broth of Boletus edulis. Journal of basic microbiology. 2007 Apr; 47(2):191-3. doi: 10.1002/jobm.200610260. [PMID: 17440922]
  • Li Cao, Jintae Lee, Wilfred Chen, Thomas K Wood. Enantioconvergent production of (R)-1-phenyl-1,2-ethanediol from styrene oxide by combining the Solanum tuberosum and an evolved Agrobacterium radiobacter AD1 epoxide hydrolases. Biotechnology and bioengineering. 2006 Jun; 94(3):522-9. doi: 10.1002/bit.20860. [PMID: 16498626]
  • Paola Manini, Roberta Andreoli, Diana Poli, Giuseppe De Palma, Antonio Mutti, Wilfried M A Niessen. Liquid chromatography/electrospray tandem mass spectrometry characterization of styrene metabolism in man and in rat. Rapid communications in mass spectrometry : RCM. 2002; 16(24):2239-48. doi: 10.1002/rcm.848. [PMID: 12478566]
  • Magdy Y Shamy, Hazem H Osman, Kamal M Kandeel, Nehad M Abdel-Moneim, Said Khalid F El. DNA single strand breaks induced by low levels of occupational exposure to styrene: the gap between standards and reality. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 2002; 21(1):57-61. doi: NULL. [PMID: 11934013]
  • L Yang, X Chen, L Jia, H Zou, Y Zhang. [Hydrophobic membrane chromatography for fast purification of biological macromolecules]. Se pu = Chinese journal of chromatography. 1999 Jul; 17(4):335-8. doi: NULL. [PMID: 12552843]
  • K Yeowell-O'Connell, Z Jin, S M Rappaport. Determination of albumin and hemoglobin adducts in workers exposed to styrene and styrene oxide. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 1996 Mar; 5(3):205-15. doi: . [PMID: 8833621]
  • S Chakrabarti, M A Duhr, M Senécal-Quevillon, C L Richer. Dose-dependent genotoxic effects of styrene on human blood lymphocytes and the relationship to its oxidative and metabolic effects. Environmental and molecular mutagenesis. 1993; 22(2):85-92. doi: 10.1002/em.2850220206. [PMID: 8359157]
  • J M Midgley, R Andrew, D G Watson, N MacDonald, J L Reid, D A Williams. Dichlorotetrafluoroacetone as a derivatisation reagent in the analysis of mandelic acids in human urine. Journal of chromatography. 1990 May; 527(2):259-65. doi: 10.1016/s0378-4347(00)82110-6. [PMID: 2387876]
  • L Drummond, J Caldwell, H K Wilson. The stereoselectivity of 1,2-phenylethanediol and mandelic acid metabolism and disposition in the rat. Xenobiotica; the fate of foreign compounds in biological systems. 1990 Feb; 20(2):159-68. doi: 10.3109/00498259009047151. [PMID: 2333712]
  • M Korn, R Wodarz, K Drysch, W Schoknecht, F W Schmahl. Stereometabolism of styrene in man: gas chromatographic determination of phenylethyleneglycol enantiomers and phenylethanol isomers in the urine of occupationally-exposed persons. Archives of toxicology. 1985 Dec; 58(2):110-4. doi: 10.1007/bf00348319. [PMID: 2418806]
  • E Wigaeus, A Löf, M B Nordqvist. Uptake, distribution, metabolism, and elimination of styrene in man. A comparison between single exposure and co-exposure with acetone. British journal of industrial medicine. 1984 Nov; 41(4):539-46. doi: 10.1136/oem.41.4.539. [PMID: 6498116]
  • A Löf, E Gullstrand, E Lundgren, M B Nordqvist. Occurrence of styrene-7,8-oxide and styrene glycol in mouse after the administration of styrene. Scandinavian journal of work, environment & health. 1984 Jun; 10(3):179-87. doi: 10.5271/sjweh.2345. [PMID: 6474112]
  • E Wigaeus, A Löf, R Bjurström, M B Nordqvist. Exposure to styrene. Uptake, distribution, metabolism and elimination in man. Scandinavian journal of work, environment & health. 1983 Dec; 9(6):479-88. doi: 10.5271/sjweh.2385. [PMID: 6673105]
  • A Löf, E Gullstrand, M Byfält Nordqvist. Tissue distribution of styrene, styrene glycol and more polar styrene metabolites in the mouse. Scandinavian journal of work, environment & health. 1983 Oct; 9(5):419-30. doi: 10.5271/sjweh.2392. [PMID: 6673100]