5-Methyltryptophan (BioDeep_00000669826)
Secondary id: BioDeep_00000897503
代谢物信息卡片
5-Methyl-DL-tryptophan
化学式: C12H14N2O2 (218.1055)
中文名称: 5-甲基-L-色氨酸, 5-甲基-DL-色氨酸
谱图信息:
最多检出来源 Homo sapiens(general) 100%
分子结构信息
SMILES: CC1=CC2=C(C=C1)NC=C2CC(C(=O)O)N
InChI: InChI=1S/C12H14N2O2/c1-7-2-3-11-9(4-7)8(6-14-11)5-10(13)12(15)16/h2-4,6,10,14H,5,13H2,1H3,(H,15,16)
描述信息
A tryptophan derivative that is tryptophan substituted by a methyl group at position 5 of the indole ring.
同义名列表
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:52527
- ChEBI: CHEBI:52524
- PubChem: 150990
- PubChem: 92852
- ChEMBL: CHEMBL569600
- CAS: 154-06-3
- CAS: 951-55-3
- MetaboLights: MTBLC52527
- MetaboLights: MTBLC52524
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Franz Marielle Nogoy, Yu Jin Jung, Kwon-Kyoo Kang, Yong-Gu Cho. Physico-chemical characterization and transcriptome analysis of 5-methyltryptophan resistant lines in rice.
PloS one.
2019; 14(9):e0222262. doi:
10.1371/journal.pone.0222262. [PMID: 31532784] - Priyanka Verma, Ajay K Mathur, Karuna Shanker. Increased availability of tryptophan in 5-methyltryptophan-tolerant shoots of Catharanthus roseus and their postharvest in vivo elicitation induces enhanced vindoline production.
Applied biochemistry and biotechnology.
2012 Oct; 168(3):568-79. doi:
10.1007/s12010-012-9797-2. [PMID: 22798187] - Takeshi Nishimura, Kiminori Toyooka, Mayuko Sato, Sachiko Matsumoto, M Mercedes Lucas, Miroslav Strnad, Frantisek Baluska, Tomokazu Koshiba. Immunohistochemical observation of indole-3-acetic acid at the IAA synthetic maize coleoptile tips.
Plant signaling & behavior.
2011 Dec; 6(12):2013-22. doi:
10.4161/psb.6.12.18080. [PMID: 22112455] - Hiroaki Saika, Akira Oikawa, Fumio Matsuda, Haruko Onodera, Kazuki Saito, Seiichi Toki. Application of gene targeting to designed mutation breeding of high-tryptophan rice.
Plant physiology.
2011 Jul; 156(3):1269-77. doi:
10.1104/pp.111.175778. [PMID: 21543727] - Tengfang Huang, Takayuki Tohge, Anna Lytovchenko, Alisdair R Fernie, Georg Jander. Pleiotropic physiological consequences of feedback-insensitive phenylalanine biosynthesis in Arabidopsis thaliana.
The Plant journal : for cell and molecular biology.
2010 Sep; 63(5):823-35. doi:
10.1111/j.1365-313x.2010.04287.x. [PMID: 20598094] - Seema Singh, Susanna A Braus-Stromeyer, Christian Timpner, Van Tuan Tran, Gertrud Lohaus, Michael Reusche, Jessica Knüfer, Thomas Teichmann, Andreas von Tiedemann, Gerhard H Braus. Silencing of Vlaro2 for chorismate synthase revealed that the phytopathogen Verticillium longisporum induces the cross-pathway control in the xylem.
Applied microbiology and biotechnology.
2010 Feb; 85(6):1961-76. doi:
10.1007/s00253-009-2269-0. [PMID: 19826808] - Marc Morant, Claus Ekstrøm, Peter Ulvskov, Charlotte Kristensen, Mats Rudemo, Carl Erik Olsen, Jørgen Hansen, Kirsten Jørgensen, Bodil Jørgensen, Birger Lindberg Møller, Søren Bak. Metabolomic, transcriptional, hormonal, and signaling cross-talk in superroot2.
Molecular plant.
2010 Jan; 3(1):192-211. doi:
10.1093/mp/ssp098. [PMID: 20008451] - Suryadevara S Rao, Lewamy Mamadou, Matt McConnell, Raghuveer Polisetty, Prachuab Kwanyuen, David Hildebrand. Non-antibiotic selection systems for soybean somatic embryos: the lysine analog aminoethyl-cysteine as a selection agent.
BMC biotechnology.
2009 Nov; 9(?):94. doi:
10.1186/1472-6750-9-94. [PMID: 19922622] - Masashi Yamada, Katie Greenham, Michael J Prigge, Philip J Jensen, Mark Estelle. The TRANSPORT INHIBITOR RESPONSE2 gene is required for auxin synthesis and diverse aspects of plant development.
Plant physiology.
2009 Sep; 151(1):168-79. doi:
10.1104/pp.109.138859. [PMID: 19625638] - Pierluigi Barone, Xing-Hai Zhang, Jack M Widholm. Tobacco plastid transformation using the feedback-insensitive anthranilate synthase [alpha]-subunit of tobacco (ASA2) as a new selectable marker.
Journal of experimental botany.
2009; 60(11):3195-202. doi:
10.1093/jxb/erp160. [PMID: 19553372] - Paoyuan Hsiao, Sanjaya, Ruey-Chih Su, Jaime A Teixeira da Silva, Ming-Tsair Chan. Plant native tryptophan synthase beta 1 gene is a non-antibiotic selection marker for plant transformation.
Planta.
2007 Mar; 225(4):897-906. doi:
10.1007/s00425-006-0405-y. [PMID: 17039373] - D S Kim, I S Lee, C S Jang, S-Y Kang, Y W Seo. Characterization of the altered anthranilate synthase in 5-methyltryptophan-resistant rice mutants.
Plant cell reports.
2005 Aug; 24(6):357-65. doi:
10.1007/s00299-005-0943-y. [PMID: 15776237] - F-Y Tsai, J E Brotherton, J M Widholm. Overexpression of the feedback-insensitive anthranilate synthase gene in tobacco causes tryptophan accumulation.
Plant cell reports.
2005 Jan; 23(8):548-56. doi:
10.1007/s00299-004-0849-0. [PMID: 15375628] - Shi-Yun Chen. Feedback-insensitive anthranilate synthase gene as a novel selectable marker for soybean transformation.
Sheng wu gong cheng xue bao = Chinese journal of biotechnology.
2004 Sep; 20(5):646-51. doi:
". [PMID: 15973983] - H-J Cho, J E Brotherton, J M Widholm. Use of the tobacco feedback-insensitive anthranilate synthase gene (ASA2) as a selectable marker for legume hairy root transformation.
Plant cell reports.
2004 Aug; 23(1-2):104-13. doi:
10.1007/s00299-004-0789-8. [PMID: 15168071] - D S Kim, I S Lee, C S Jang, S Y Kang, H S Song, Y I Lee, Y W Seo. Development of AFLP-derived STS markers for the selection of 5-methyltryptophan-resistant rice mutants.
Plant cell reports.
2004 Aug; 23(1-2):71-80. doi:
10.1007/s00299-004-0790-2. [PMID: 15064855] - Tetsuya Matsukawa, Atsushi Ishihara, Hajime Iwamura. Induction of anthranilate synthase activity by elicitors in oats.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2002 Jan; 57(1-2):121-8. doi:
10.1515/znc-2002-1-221. [PMID: 11926523] - X H Zhang, J E Brotherton, J M Widholm, A R Portis. Targeting a nuclear anthranilate synthase alpha-subunit gene to the tobacco plastid genome results in enhanced tryptophan biosynthesis. Return of a gene to its pre-endosymbiotic origin.
Plant physiology.
2001 Sep; 127(1):131-41. doi:
10.1104/pp.127.1.131. [PMID: 11553741] - Y Tozawa, H Hasegawa, T Terakawa, K Wakasa. Characterization of rice anthranilate synthase alpha-subunit genes OASA1 and OASA2. Tryptophan accumulation in transgenic rice expressing a feedback-insensitive mutant of OASA1.
Plant physiology.
2001 Aug; 126(4):1493-506. doi:
10.1104/pp.126.4.1493. [PMID: 11500548] - Y Zhao, S K Christensen, C Fankhauser, J R Cashman, J D Cohen, D Weigel, J Chory. A role for flavin monooxygenase-like enzymes in auxin biosynthesis.
Science (New York, N.Y.).
2001 Jan; 291(5502):306-9. doi:
10.1126/science.291.5502.306. [PMID: 11209081] - H J Cho, J E Brotherton, H S Song, J M Widholm. Increasing tryptophan synthesis in a forage legume Astragalus sinicus by expressing the tobacco feedback-insensitive anthranilate synthase (ASA2) gene.
Plant physiology.
2000 Jul; 123(3):1069-76. doi:
10.1104/pp.123.3.1069. [PMID: 10889256] - H Kisaka, M Kisaka, H Y Lee, T Kameya. Isolation of a cDNA for tryptophan synthase beta from rice and studies of its expression in a 5-methyltryptophan-resistant mutant of rice.
Plant molecular biology.
1998 Nov; 38(5):875-8. doi:
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