Kitasamycin (BioDeep_00000665714)

 

Secondary id: BioDeep_00000009422

natural product


代谢物信息卡片


Leucomycin V

化学式: C35H59NO13 (701.3986204)
中文名称: 吉他霉素
谱图信息: 最多检出来源 Mentha canadensis(plant) 90.91%

分子结构信息

SMILES: CC1CC=CC=CC(C(CC(C(C(C(CC(=O)O1)O)OC)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)O)(C)O)N(C)C)O)CC=O)C)O
InChI: InChI=1S/C35H59NO13/c1-19-16-23(14-15-37)31(32(44-8)25(39)17-26(40)45-20(2)12-10-9-11-13-24(19)38)49-34-29(41)28(36(6)7)30(21(3)47-34)48-27-18-35(5,43)33(42)22(4)46-27/h9-11,13,15,19-25,27-34,38-39,41-43H,12,14,16-18H2,1-8H3/b10-9+,13-11+/t19-,20-,21-,22+,23+,24+,25-,27+,28-,29-,30-,31+,32+,33+,34+,35-/m1/s1

描述信息

A macrolide antibiotic produced by Streptomyces kitasatoensis, showing activity against a wide spectrum of pathogens.
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007933 - Leucomycins

同义名列表

3 个代谢物同义名

Leucomycin V; Kitasamycin; Leucomycin V



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

19 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Feng Xu, Jiayong Yu, Rongrong Zhang, Zeming Zhang, Aili Sun, Xizhi Shi, Yinliang Wu. A green and rapid analytical method for determination of kitasamycin in animal feedstuffs by ultra-high performance liquid chromatography tandem mass spectrometry. Journal of chromatography. A. 2022 Aug; 1676(?):463203. doi: 10.1016/j.chroma.2022.463203. [PMID: 35753112]
  • Miao Yu, Chunlong Mu, Yuxiang Yang, Chuanjian Zhang, Yong Su, Zan Huang, Kaifan Yu, Weiyun Zhu. Increases in circulating amino acids with in-feed antibiotics correlated with gene expression of intestinal amino acid transporters in piglets. Amino acids. 2017 09; 49(9):1587-1599. doi: 10.1007/s00726-017-2451-0. [PMID: 28623466]
  • Nengfei Ding, Weidong Li, Chen Liu, Qinglin Fu, Bin Guo, Hua Li, Ningyu Li, Yicheng Lin. Decline in extractable kitasamycin during the composting of kitasamycin manufacturing waste with dairy manure and sawdust. Journal of environmental management. 2014 Feb; 134(?):39-46. doi: 10.1016/j.jenvman.2013.12.030. [PMID: 24463847]
  • Sabine Glasl, Pavel Mucaji, Ingrid Werner, Armin Presser, Johann Jurenitsch. Sesquiterpenes and flavonoid aglycones from a Hungarian taxon of the Achillea millefolium group. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2002 Nov; 57(11-12):976-82. doi: 10.1515/znc-2002-11-1203. [PMID: 12562079]
  • A G Kirmukov, M I Aĭzikov, S A Rasulova, G P Sidiakin, I D Sham'ianov, V M Malikov. [The angioprotector and hypolipemic activity of leukomizin in experimental atherosclerosis]. Farmakologiia i toksikologiia. 1991 May; 54(3):35-7. doi: . [PMID: 1915817]
  • A B Hassan, A H Atta, Z I Soliman. Pharmacokinetics and tissue residues of kitasamycin in healthy and diseased broilers. DTW. Deutsche tierarztliche Wochenschrift. 1990 Aug; 97(8):315-7. doi: NULL. [PMID: 2209453]
  • G Hesse, H Hoffmann, H Fricke, W F Fleck. [Protein binding of the macrolide antibiotic turimycin. Methodologic effects on results]. Die Pharmazie. 1983 Nov; 38(11):740-3. doi: NULL. [PMID: 6669594]
  • H Hoffmann, A Härtl. Pharmacokinetic characteristics of the new veterinary antibiotic turimycin. Polish journal of pharmacology and pharmacy. 1980 Mar; 32(2):211-6. doi: NULL. [PMID: 7454625]
  • A Härtl, H Hoffmann. Toxicological studies on the new veterinary antibiotic turimycin. Polish journal of pharmacology and pharmacy. 1980 Mar; 32(2):217-24. doi: NULL. [PMID: 7454626]