Tetraglucoside (BioDeep_00000665273)

   


代谢物信息卡片


α-D-Glucopyranosyl-(1->6)-α-D-glucopyranosyl-(1->4)-α-D-glucopyranosyl-(1->4)-D-glucose

化学式: C24H42O21 (666.2218482000001)
中文名称: Glcα1-6Glcα1-4Glcα1-4Glc
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(C1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3C(OC(C(C3O)O)OC(C(CO)O)C(C(C=O)O)O)CO)O)O)O)O)O)O)O
InChI: InChI=1S/C24H42O21/c25-1-6(29)11(31)20(7(30)2-26)44-24-19(39)16(36)21(9(4-28)42-24)45-23-18(38)15(35)13(33)10(43-23)5-40-22-17(37)14(34)12(32)8(3-27)41-22/h1,6-24,26-39H,2-5H2/t6-,7+,8+,9+,10+,11+,12+,13+,14-,15-,16+,17+,18+,19+,20+,21+,22-,23+,24+/m0/s1

描述信息

同义名列表

2 个代谢物同义名

α-D-Glucopyranosyl-(1->6)-α-D-glucopyranosyl-(1->4)-α-D-glucopyranosyl-(1->4)-D-glucose; Tetraglucoside



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Omid Aryani, Masoumeh Dehghan Manshadi, Mahdi Tondar, Elham Khalili, Behnam Kamalidehghan, Fatemeh Ahmadipour, Somayeh Fani, Massoud Houshmand. A newly identified c.1824_1828dupATACG mutation in exon 13 of the GAA gene in infantile-onset glycogen storage disease type II (Pompe disease). Molecular biology reports. 2014 Sep; 41(9):6211-4. doi: 10.1007/s11033-014-3500-3. [PMID: 24976573]
  • Joaquín Bobillo Lobato, Pilar Durán Parejo, Pedro Tejero Díez, Luis M Jiménez Jiménez. [Tetra-saccharide glucose as a diagnostic biomarker for Pompe disease: a study with 35 patients]. Medicina clinica. 2013 Aug; 141(3):106-10. doi: 10.1016/j.medcli.2013.02.035. [PMID: 23756115]
  • Chihiro Yonee, Mitsuo Toyoshima, Sarah P Young, Shinsuke Maruyama, Itsuro Higuchi, Aya Narita, Yoshihiro Maegaki, Eiji Nanba, Kousaku Ohno, Yoshifumi Kawano. Quantitative computed tomography for enzyme replacement therapy in Pompe disease. Brain & development. 2012 Nov; 34(10):834-9. doi: 10.1016/j.braindev.2012.01.013. [PMID: 22521436]
  • Victoria Manwaring, Helen Prunty, Katie Bainbridge, Derek Burke, Niamh Finnegan, Rebecca Franses, Amanda Lam, Ashok Vellodi, Simon Heales. Urine analysis of glucose tetrasaccharide by HPLC; a useful marker for the investigation of patients with Pompe and other glycogen storage diseases. Journal of inherited metabolic disease. 2012 Mar; 35(2):311-6. doi: 10.1007/s10545-011-9360-2. [PMID: 21687968]
  • Sarah P Young, Monique Piraud, Jennifer L Goldstein, Haoyue Zhang, Catherine Rehder, Pascal Laforet, Priya S Kishnani, David S Millington, Mustafa R Bashir, Deeksha S Bali. Assessing disease severity in Pompe disease: the roles of a urinary glucose tetrasaccharide biomarker and imaging techniques. American journal of medical genetics. Part C, Seminars in medical genetics. 2012 Feb; 160C(1):50-8. doi: 10.1002/ajmg.c.31320. [PMID: 22252961]
  • Yoav H Messinger, Nancy J Mendelsohn, William Rhead, David Dimmock, Eli Hershkovitz, Michael Champion, Simon A Jones, Rebecca Olson, Amy White, Cara Wells, Deeksha Bali, Laura E Case, Sarah P Young, Amy S Rosenberg, Priya S Kishnani. Successful immune tolerance induction to enzyme replacement therapy in CRIM-negative infantile Pompe disease. Genetics in medicine : official journal of the American College of Medical Genetics. 2012 Jan; 14(1):135-42. doi: 10.1038/gim.2011.4. [PMID: 22237443]
  • Johannes Brettschneider, Troy D Jaskowski, Hayrettin Tumani, Sana Abdul, Dee Husebye, Haniah Seraj, Harry R Hill, Ella Fire, Larissa Spector, Jennifer Yarden, Nir Dotan, John W Rose. Serum anti-GAGA4 IgM antibodies differentiate relapsing remitting and secondary progressive multiple sclerosis from primary progressive multiple sclerosis and other neurological diseases. Journal of neuroimmunology. 2009 Dec; 217(1-2):95-101. doi: 10.1016/j.jneuroim.2009.07.017. [PMID: 19879655]
  • Sarah P Young, Haoyue Zhang, Deyanira Corzo, Beth L Thurberg, Deeksha Bali, Priya S Kishnani, David S Millington. Long-term monitoring of patients with infantile-onset Pompe disease on enzyme replacement therapy using a urinary glucose tetrasaccharide biomarker. Genetics in medicine : official journal of the American College of Medical Genetics. 2009 Jul; 11(7):536-41. doi: 10.1097/gim.0b013e3181a87867. [PMID: 19521244]
  • Mikael Schwarz, Larissa Spector, Monica Gortler, Oori Weisshaus, Lea Glass-Marmor, Arnon Karni, Nir Dotan, Ariel Miller. Serum anti-Glc(alpha1,4)Glc(alpha) antibodies as a biomarker for relapsing-remitting multiple sclerosis. Journal of the neurological sciences. 2006 May; 244(1-2):59-68. doi: 10.1016/j.jns.2005.12.006. [PMID: 16480743]
  • Yan An, Sarah P Young, Priya S Kishnani, David S Millington, Andrea Amalfitano, Deyanira Corz, Yuan-Tsong Chen. Glucose tetrasaccharide as a biomarker for monitoring the therapeutic response to enzyme replacement therapy for Pompe disease. Molecular genetics and metabolism. 2005 Aug; 85(4):247-54. doi: 10.1016/j.ymgme.2005.03.010. [PMID: 15886040]
  • Sarah P Young, Robert D Stevens, Yan An, Yuan-Tsong Chen, David S Millington. Analysis of a glucose tetrasaccharide elevated in Pompe disease by stable isotope dilution-electrospray ionization tandem mass spectrometry. Analytical biochemistry. 2003 May; 316(2):175-80. doi: 10.1016/s0003-2697(03)00056-3. [PMID: 12711338]
  • Y An, S P Young, S L Hillman, J L Van Hove, Y T Chen, D S Millington. Liquid chromatographic assay for a glucose tetrasaccharide, a putative biomarker for the diagnosis of Pompe disease. Analytical biochemistry. 2000 Dec; 287(1):136-43. doi: 10.1006/abio.2000.4838. [PMID: 11078593]
  • K Oberholzer, A C Sewell. Unique oligosaccharide (apparently glucotetrasaccharide) in urine of patients with glycogen storage diseases. Clinical chemistry. 1990 Jul; 36(7):1381. doi: NULL. [PMID: 2372959]
  • W T Wang, J Kumlien, S Ohlson, A Lundblad, D Zopf. Analysis of a glucose-containing tetrasaccharide by high-performance liquid affinity chromatography. Analytical biochemistry. 1989 Oct; 182(1):48-53. doi: 10.1016/0003-2697(89)90716-1. [PMID: 2604047]
  • A Lundblad, K Schroer, D Zopf. Affinity purification of a glucose-containing oligosaccharide using a monoclonal antibody. Journal of immunological methods. 1984 Mar; 68(1-2):227-34. doi: 10.1016/0022-1759(84)90153-4. [PMID: 6707479]
  • M A Chester, A Lundblad, A Häger, S Sjöblad, C Loonen, J M Tager, D Zopf. Increased urinary excretion of a glycogen-derived tetrasaccharide in heterozygotes with glycogen storage diseases type II and III. Lancet (London, England). 1983 Apr; 1(8331):994-5. doi: 10.1016/s0140-6736(83)92122-0. [PMID: 6132305]
  • D A Zopf, R E Levinson, A Lundblad. Determination of a glucose-containing tetrasaccharide in urine by radioimmunoassay. Journal of immunological methods. 1982; 48(1):109-19. doi: 10.1016/0022-1759(82)90215-0. [PMID: 7057040]