Madurmycin (BioDeep_00000649665)
Chemicals and Drugs
代谢物信息卡片
化学式: C47H83NO17 (933.5660708)
中文名称: 马杜霉素, 马度米星
谱图信息:
最多检出来源 () 0%
Last reviewed on 2024-08-12.
Cite this Page
Madurmycin. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/madurmycin (retrieved
2024-11-23) (BioDeep RN: BioDeep_00000649665). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
分子结构信息
SMILES: CC1CC(C(OC1C2CC(C(O2)C3(CCC(O3)C4(CCC5(O4)CC(C(C(O5)C(C)C6C(C(C(C(O6)(CC(=O)O)O)C)OC)OC)C)O)C)C)OC7CC(C(C(O7)C)OC)OC)(C)O)C.N
InChI: InChI=1S/C47H80O17.H3N/c1-23-18-24(2)45(9,51)61-36(23)31-19-32(58-35-20-30(53-10)40(55-12)28(6)57-35)42(59-31)44(8)15-14-33(60-44)43(7)16-17-46(64-43)21-29(48)25(3)37(62-46)26(4)38-41(56-13)39(54-11)27(5)47(52,63-38)22-34(49)50
描述信息
C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C277 - Antiprotozoal Agent
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
Maduramicin ammonium (Maduramycin ammonium) is isolated from the actinomycete?Actinomadura rubra. Maduramicin ammonium (Maduramycin ammonium) is an anticoccidial agent for the the treatment of Eimeria spp., E. adenoeides, E. gallopavonis, and E. dispersa infection[1]. Maduramicin ammonium (Maduramycin ammonium) induces cell apoptosis in chicken myocardial cells via intrinsic and extrinsic pathways[2].
同义名列表
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:189929
- KEGGdrug: D04830
- PubChem: 68595
- DrugBank: DB11525
- ChEMBL: CHEMBL2105807
- CAS: 61991-54-6
- medchemexpress: HY-N7071A
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Sawsan S Elbasuni, Hanan A A Taie, Samah M Abdel Gawad, Reda E L Kamar, Hala El Daous, Marwa Darweish, Mai O Nada, Walaa F SaadEldin, Marwa I Abdel Haleem. Efficacy of dietary supplements of Glycyrrhiza glabra (Licorice) and maduramicin alone or in combination with Eimeria tenella infected chicks: A clinical study and molecular docking.
Open veterinary journal.
2024 Jan; 14(1):225-241. doi:
10.5455/ovj.2024.v14.i1.20. [PMID: 38633172] - Yuxiang Xie, Bing Huang, Lingyang Xu, Qiping Zhao, Shunhai Zhu, Huanzhi Zhao, Hui Dong, Hongyu Han. Comparative Transcriptome Analyses of Drug-sensitive and Drug-resistant Strains of Eimeria tenella by RNA-sequencing.
The Journal of eukaryotic microbiology.
2020 07; 67(4):406-416. doi:
10.1111/jeu.12790. [PMID: 32027445] - Mohsin Raza, Hina Bharti, Aakriti Singal, Alo Nag, Prahlad C Ghosh. Long circulatory liposomal maduramicin inhibits the growth of Plasmodium falciparum blood stages in culture and cures murine models of experimental malaria.
Nanoscale.
2018 Jul; 10(28):13773-13791. doi:
10.1039/c8nr02442a. [PMID: 29995025] - G-Y Wang, P Tu, X Chen, Y-G Guo, S-X Jiang. Effect of three polyether ionophores on pharmacokinetics of florfenicol in male broilers.
Journal of veterinary pharmacology and therapeutics.
2013 Oct; 36(5):494-501. doi:
10.1111/jvp.12020. [PMID: 23067134] - F C Guo, X Suo, G Z Zhang, J Z Shen. Efficacy of decoquinate against drug sensitive laboratory strains of Eimeria tenella and field isolates of Eimeria spp. in broiler chickens in China.
Veterinary parasitology.
2007 Jul; 147(3-4):239-45. doi:
10.1016/j.vetpar.2007.04.002. [PMID: 17485176] - N Sharma, A Bhalla, S Varma, S Jain, S Singh. Toxicity of maduramicin.
Emergency medicine journal : EMJ.
2005 Dec; 22(12):880-2. doi:
10.1136/emj.2004.020883. [PMID: 16299200] - Tersem Singh, R P Gupta. Clinico-haematological and mineral studies on experimental maduramicin toxicity in chickens.
Veterinary parasitology.
2003 Oct; 116(4):345-53. doi:
10.1016/j.vetpar.2003.07.009. [PMID: 14580805] - M T Gutiérrez-Lugo, B Lotina-Hennsen, A Farrés, S Sánchez, R Mata. Phytotoxic and photosynthetic activities of maduramicin and maduramicin methyl ester.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
1999 May; 54(5-6):325-32. doi:
10.1515/znc-1999-5-606. [PMID: 10431386] - D G Kennedy, W J Blanchflower, B C O'Dornan. Development of an ELISA for maduramicin and determination of the depletion kinetics of maduramicin residues in poultry.
Food additives and contaminants.
1997 Jan; 14(1):27-33. doi:
10.1080/02652039709374494. [PMID: 9059580] - M J Arrowood, J R Mead, L Xie, X You. In vitro anticryptosporidial activity of dinitroaniline herbicides.
FEMS microbiology letters.
1996 Mar; 136(3):245-9. doi:
10.1111/j.1574-6968.1996.tb08056.x. [PMID: 8867379] - J Lehel, P Laczay, Z Móra, G Semjén. Toxicological studies on potentiated ionophores in chickens. II. Compatibility study.
Acta veterinaria Hungarica.
1995; 43(2-3):335-45. doi:
. [PMID: 7491873] - J Lehel, P Laczay, Z Móra, G Semjén. Toxicological studies on potentiated ionophores in chickens. I. Tolerance study.
Acta veterinaria Hungarica.
1995; 43(2-3):321-33. doi:
NULL. [PMID: 7491872] - A Shlosberg, A Harmelin, S Perl, G Pano, M Davidson, U Orgad, U Kali, A Bor, M Van Ham, G Hoida. Cardiomyopathy in cattle induced by residues of the coccidiostat maduramicin in poultry litter given as a feedstuff.
Veterinary research communications.
1992; 16(1):45-58. doi:
10.1007/bf01839204. [PMID: 1598754] - N Fourie, S S Bastianello, L Prozesky, P W Nel, T S Kellerman. Cardiomyopathy of ruminants induced by the litter of poultry fed on rations containing the ionophore antibiotic, maduramicin. I. Epidemiology, clinical signs and clinical pathology.
The Onderstepoort journal of veterinary research.
1991 Dec; 58(4):291-6. doi:
NULL. [PMID: 1780131] - W F Fleck, D G Strauss, J Meyer, G Porstendorfer. Fermentation, isolation, and biological activity of maduramycin: a new antibiotic from Actinomadura rubra.
Zeitschrift fur allgemeine Mikrobiologie.
1978; 18(6):389-98. doi:
10.1002/jobm.3630180602. [PMID: 362738]