FA 4:0;O (BioDeep_00000629015)

Main id: BioDeep_00000014340

Secondary id: BioDeep_00000405272

PANOMIX_OTCML-2023


代谢物信息卡片


(R)-2-hydroxybutanoic acid;D-2-hydroxybutanoic acid;D-2-hydroxybutyric acid

化学式: C4H8O3 (104.0473418)
中文名称: (s)-3-羟基丁酸
谱图信息: 最多检出来源 Homo sapiens(lipidomics) 4.17%

分子结构信息

SMILES: C(=O)(O)C[C@@H](O)C
InChI: InChI=1S/C4H8O3/c5-3-1-2-4(6)7/h5H,1-3H2,(H,6,7)

描述信息

(S)-3-Hydroxybutanoic acid is a normal human metabolite, that has been found elevated in geriatric patients remitting from depression. In humans, 3-Hydroxybutyric acid is synthesized in the liver from acetyl-CoA, and can be used as an energy source by the brain when blood glucose is low.

同义名列表

29 个代谢物同义名

(3S)-3-hydroxybutanoic acid; (S)-3-Hydroxybutanoic acid; (S)-3-Hydroxybutyric acid; FA 4:0;O; (R)-2-hydroxybutanoic acid;D-2-hydroxybutanoic acid;D-2-hydroxybutyric acid; (2R)-2-hydroxybutanoic acid; (R)-2-HYDROXYBUTYRIC ACID; 2R-methyl-3-hydroxy-propanoic acid; 3R-hydroxy-isobutyric acid; 2S-hydroxy-butanoic acid; 2S-Hydroxybutanoic acid; 2-Hydroxybutanoic acid; (R)-(-)-beta-Hydroxybutyric acid; Butyric acid, 3-hydroxy-, D-(-)-; Butanoic acid, 3-hydroxy-, (R)-; (R)-(-)-3-Hydroxybutyric acid; (R)-beta-Hydroxybutanoic acid; (R)-beta-Hydroxybutyric acid; (-)-3-Hydroxy-n-butyric acid; (-)-3-Hydroxybutyric acid; 3R-hydroxy-butanoic acid; (R)-3-; 4-hydroxy-butanoic acid; 4-hydroxy-butyric acid; (+/-)alpha-hydoxy butyric acid; 2-hydroxy-butanoic acid; (S)-β-Hydroxybutanoic acid; L-(+)-3-Hydroxybutyric acid; L-β-Hydroxybutyric acid



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Valentina L Kouznetsova, Igor F Tsigelny, Megha A Nagle, Sanjay K Nigam. Elucidation of common pharmacophores from analysis of targeted metabolites transported by the multispecific drug transporter-Organic anion transporter1 (Oat1). Bioorganic & medicinal chemistry. 2011 Jun; 19(11):3320-40. doi: 10.1016/j.bmc.2011.04.045. [PMID: 21571536]
  • Gregory Kaler, David M Truong, Akash Khandelwal, Megha Nagle, Satish A Eraly, Peter W Swaan, Sanjay K Nigam. Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members. The Journal of biological chemistry. 2007 Aug; 282(33):23841-53. doi: 10.1074/jbc.m703467200. [PMID: 17553798]
  • J E Manning Fox, D Meredith, A P Halestrap. Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle. The Journal of physiology. 2000 Dec; 529 Pt 2(?):285-93. doi: 10.1111/j.1469-7793.2000.00285.x. [PMID: 11101640]