Isopulegol (BioDeep_00000620222)

   


代谢物信息卡片


(1R,2S,5R)-5-methyl-2-(prop-1-en-2-yl)cyclohexan-1-ol

化学式: C10H18O (154.1357578)
中文名称: (-)-异蒲勒醇, 异蒲勒醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1CCC(C(C1)O)C(=C)C
InChI: InChI=1S/C10H18O/c1-7(2)9-5-4-8(3)6-10(9)11/h8-11H,1,4-6H2,2-3H3

描述信息

A natural product found in Citrus hystrix.

同义名列表

18 个代谢物同义名

Isopulegol; (-)-Isopulegol; (1R,2S,5R)-5-methyl-2-(prop-1-en-2-yl)cyclohexan-1-ol; 5-Methyl-2-(1-methylethenyl)-(1R,2S,5R)-cyclohexanol; (1R,3R,4S)-(-)-P-Menth-8-en-3-ol; (-)-L-Isopulegol; L-Isopulegol; 5-Methyl-2-(1-methylethenyl)cyclohexanol, 9ci; 5-methyl-2-(prop-1-en-2-yl)cyclohexan-1-ol; Cyclohexanol,5-methyl-2-(1-methylethenyl)-; 5-Methyl-2-(1-methylethenyl)-cyclohexanol; 5-Methyl-2-(1-methylvinyl)cyclohexan-1-ol; 1-Methyl-4-isopropenylcyclohexan-3-ol; 2-Isopropenyl-5-methylcyclohexanol; P-8(9)-Menthen-3-ol; 8(9)-P-Menthen-3-ol; p-Menth-8-en-3-ol; FEMA 2962



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

28 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Karunanithi Kalaivani, Chandrasekaran Sankaranarayanan. Modulatory effect of isopulegol on hepatic key enzymes of glucose metabolism in high-fat diet/streptozotocin-induced diabetic rats. Archives of physiology and biochemistry. 2021 Aug; 127(4):318-326. doi: 10.1080/13813455.2019.1638415. [PMID: 31291130]
  • Irina V Ilyina, Oksana S Patrusheva, Vladimir V Zarubaev, Maria A Misiurina, Alexander V Slita, Iana L Esaulkova, Dina V Korchagina, Yuri V Gatilov, Sophia S Borisevich, Konstantin P Volcho, Nariman F Salakhutdinov. Influenza antiviral activity of F- and OH-containing isopulegol-derived octahydro-2H-chromenes. Bioorganic & medicinal chemistry letters. 2021 01; 31(?):127677. doi: 10.1016/j.bmcl.2020.127677. [PMID: 33171219]
  • Chandrasekaran Sankaranarayanan, Karunanithi Kalaivani. Isopulegol Mitigates Hyperglycemia Mediated Oxidative and Endoplasmic Reticulum Stress in HFD/STZ Induced Diabetic Rats. Archives of medical research. 2020 04; 51(3):204-214. doi: 10.1016/j.arcmed.2020.02.001. [PMID: 32111490]
  • Xiaochang Liu, Meiying Liu, Chao Liu, Peng Quan, Yongshan Zhao, Liang Fang. An insight into the molecular mechanism of the temporary enhancement effect of isopulegol decanoate on the skin. International journal of pharmaceutics. 2017 Aug; 529(1-2):161-167. doi: 10.1016/j.ijpharm.2017.06.023. [PMID: 28610893]
  • Miyeon Jang, Junheon Kim, Kyungjae Andrew Yoon, Si Hyeock Lee, Chung Gyoo Park. Biological activity of Myrtaceae plant essential oils and their major components against Drosophila suzukii (Diptera: Drosophilidae). Pest management science. 2017 Feb; 73(2):404-409. doi: 10.1002/ps.4430. [PMID: 27607409]
  • H Tolba, H Moghrani, A Benelmouffok, D Kellou, R Maachi. Essential oil of Algerian Eucalyptus citriodora: Chemical composition, antifungal activity. Journal de mycologie medicale. 2015 Dec; 25(4):e128-33. doi: 10.1016/j.mycmed.2015.10.009. [PMID: 26597375]
  • René F Ramos Alvarenga, Baojie Wan, Taichi Inui, Scott G Franzblau, Guido F Pauli, Birgit U Jaki. Airborne antituberculosis activity of Eucalyptus citriodora essential oil. Journal of natural products. 2014 Mar; 77(3):603-10. doi: 10.1021/np400872m. [PMID: 24641242]
  • Sandeep B Rajput, S Mohan Karuppayil. Small molecules inhibit growth, viability and ergosterol biosynthesis in Candida albicans. SpringerPlus. 2013 Dec; 2(1):26. doi: 10.1186/2193-1801-2-26. [PMID: 23449869]
  • Eunae Kim, Il-Kwon Park. Fumigant antifungal activity of Myrtaceae essential oils and constituents from Leptospermum petersonii against three Aspergillus species. Molecules (Basel, Switzerland). 2012 Sep; 17(9):10459-69. doi: 10.3390/molecules170910459. [PMID: 22945026]
  • Jun Han, Soon-Il Kim, Byeoung-Ryeol Choi, Sang-Guei Lee, Young-Joon Ahn. Fumigant toxicity of lemon eucalyptus oil constituents to acaricide-susceptible and acaricide-resistant Tetranychus urticae. Pest management science. 2011 Dec; 67(12):1583-8. doi: 10.1002/ps.2216. [PMID: 21674753]
  • Maria Izabel Gomes Silva, Maria Angélica Gomes Silva, Manuel Rufino de Aquino Neto, Brinell Arcanjo Moura, Helenira Lourenço de Sousa, Everton Paulo Homem de Lavor, Patrícia Freire de Vasconcelos, Danielle Silveira Macêdo, Damião Pergentino de Sousa, Silvânia Maria Mendes Vasconcelos, Francisca Cléa Florenço de Sousa. Effects of isopulegol on pentylenetetrazol-induced convulsions in mice: possible involvement of GABAergic system and antioxidant activity. Fitoterapia. 2009 Dec; 80(8):506-13. doi: 10.1016/j.fitote.2009.06.011. [PMID: 19559770]
  • Harminder P Singh, Sunil Mittal, Shalinder Kaur, Daizy R Batish, Ravinder K Kohli. Characterization and antioxidant activity of essential oils from fresh and decaying leaves of Eucalyptus tereticornis. Journal of agricultural and food chemistry. 2009 Aug; 57(15):6962-6. doi: 10.1021/jf9012407. [PMID: 19722579]
  • Joris Vriens, Bernd Nilius, Rudi Vennekens. Herbal compounds and toxins modulating TRP channels. Current neuropharmacology. 2008 Mar; 6(1):79-96. doi: 10.2174/157015908783769644. [PMID: 19305789]
  • Soon-Young Paik, Kyung-Hee Koh, Sung-Mok Beak, Seung-Hwan Paek, Jung-Ae Kim. The essential oils from Zanthoxylum schinifolium pericarp induce apoptosis of HepG2 human hepatoma cells through increased production of reactive oxygen species. Biological & pharmaceutical bulletin. 2005 May; 28(5):802-7. doi: 10.1248/bpb.28.802. [PMID: 15863882]
  • N Dudai, Z G Weinberg, O Larkov, U Ravid, G Ashbell, E Putievsky. Changes in essential oil during enzyme-assisted ensiling of lemongrass (Cymbopogon citratus Stapf.) and lemon eucalyptus (Eucalyptus citriodora Hook). Journal of agricultural and food chemistry. 2001 May; 49(5):2262-6. doi: 10.1021/jf001324+. [PMID: 11368586]
  • H M Ferraz, M V Grazini, C M Ribeiro, U Brocksom, T J Brocksom. A short route to (-)-mintlactone by thallium(III)-mediated cyclization of (-)-isopulegol. The Journal of organic chemistry. 2000 Apr; 65(8):2606-7. doi: 10.1021/jo991802j. [PMID: 10789485]
  • P C McMinn, G M Halliday, P Waring, H K Muller. Langerhans cell depletion in gliotoxin-treated murine epidermis. Pathology. 1991 Jan; 23(1):39-44. doi: 10.3109/00313029109061439. [PMID: 1712093]