PGE2-EA (BioDeep_00000596181)

   


代谢物信息卡片


(Z)-N-(2-hydroxyethyl)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enamide

  化学式: C22H37NO5 (395.2672)
中文名称:
  谱图信息: 最多检出来源 Homo sapiens(lipidomics) 100%

分子结构信息

SMILES: CCCCCC(C=CC1C(CC(=O)C1CC=CCCCC(=O)NCCO)O)O
InChI: InChI=1S/C22H37NO5/c1-2-3-6-9-17(25)12-13-19-18(20(26)16-21(19)27)10-7-4-5-8-11-22(28)23-14-15-24/h4,7,12-13,17-19,21,24-25,27H,2-3,5-6,8-11,14-16H2,1H3,(H,23,28)/b7-4-,13-12+/t17-,18+,19+,21+/m0/s1


描述信息

同义名列表

15 个代谢物同义名

N-(11R,15S-dihydroxy-9-oxo-5Z,13E-prostadienoyl)-ethanolamine; Prostaglandin E2-EA; Prostamide-E2; NAE 20:4;O3; PGE2-EA; PME2; (Z)-N-(2-hydroxyethyl)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enamide; Prostaglandin E2 Ethanolamide; (5Z)-7-((1R,2R,3S)-3-hydroxy-2-((1E,3S)-3-hydroxyoct-1-en-1-yl)-5-oxocyclopentyl)-N-(2-hydroxyethyl)hept-5-enamide; (5Z)-7-[(1R,2R,3S)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]-N-(2-hydroxyethyl)hept-5-enamide; dinoprostone ethanolamide; PGE(2) ethanolamide; PGE2 ethanolamide; prostaglandin E(2) ethanolamide; prostamide E2



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome()

BioCyc()

PlantCyc()

代谢反应

个相关的代谢反应过程信息。

Reactome()

BioCyc()

WikiPathways()

Plant Reactome()

INOH()

PlantCyc()

COVID-19 Disease Map()

PathBank()

PharmGKB()

个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Kirsten L Brown, Jillian Davidson, Dino Rotondo. Characterisation of the prostaglandin E2-ethanolamide suppression of tumour necrosis factor-α production in human monocytic cells. Biochimica et biophysica acta. 2013 Jun; 1831(6):1098-107. doi: 10.1016/j.bbalip.2013.03.006. [PMID: 23542062]
  • Lauren L Nicotra, Megan Vu, Benjamin S Harvey, Scott D Smid. Prostaglandin ethanolamides attenuate damage in a human explant colitis model. Prostaglandins & other lipid mediators. 2013 Jan; 100-101(?):22-9. doi: 10.1016/j.prostaglandins.2013.01.003. [PMID: 23380599]
  • Joseph K Ritter, Cao Li, Min Xia, Justin L Poklis, Aron H Lichtman, Rehab A Abdullah, William L Dewey, Pin-Lan Li. Production and actions of the anandamide metabolite prostamide E2 in the renal medulla. The Journal of pharmacology and experimental therapeutics. 2012 Sep; 342(3):770-9. doi: 10.1124/jpet.112.196451. [PMID: 22685343]
  • Michelle Glass, Jiwon Hong, Timothy A Sato, Murray D Mitchell. Misidentification of prostamides as prostaglandins. Journal of lipid research. 2005 Jul; 46(7):1364-8. doi: 10.1194/jlr.c500006-jlr200. [PMID: 15863842]
  • Allan Weber, Jinsong Ni, Kah-Hiing John Ling, Andrew Acheampong, Diane D-S Tang-Liu, Robert Burk, Benjamin F Cravatt, David Woodward. Formation of prostamides from anandamide in FAAH knockout mice analyzed by HPLC with tandem mass spectrometry. Journal of lipid research. 2004 Apr; 45(4):757-63. doi: 10.1194/jlr.m300475-jlr200. [PMID: 14729864]
  • Ruth A Ross, Susan J Craib, Lesley A Stevenson, Roger G Pertwee, Andrea Henderson, John Toole, Heather C Ellington. Pharmacological characterization of the anandamide cyclooxygenase metabolite: prostaglandin E2 ethanolamide. The Journal of pharmacology and experimental therapeutics. 2002 Jun; 301(3):900-7. doi: 10.1124/jpet.301.3.900. [PMID: 12023517]