13,14-dihydro-PGE1 (BioDeep_00000594270)

   


代谢物信息卡片


9-oxo-11R,15S-dihydroxy-prostanoic acid

化学式: C20H36O5 (356.2562606)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCC(CCC1C(CC(=O)C1CCCCCCC(=O)O)O)O
InChI: InChI=1S/C20H36O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h15-17,19,21,23H,2-14H2,1H3,(H,24,25)/t15-,16+,17+,19+/m0/s1

描述信息

同义名列表

3 个代谢物同义名

13,14-dihydro-PGE1; 9-oxo-11R,15S-dihydroxy-prostanoic acid; 13,14-dihydro-Prostaglandin E1



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • T L Davis, N A Sharif. Pharmacological characterization of [(3)H]-prostaglandin E(2) binding to the cloned human EP(4) prostanoid receptor. British journal of pharmacology. 2000 Aug; 130(8):1919-26. doi: 10.1038/sj.bjp.0703525. [PMID: 10952683]
  • H Sinzinger, I Neumann, J O'Grady, W Rogatti, B A Peskar. Effects of prostaglandin E1 metabolites on the induction of arterial thromboresistance. Prostaglandins & other lipid mediators. 1998 Apr; 55(5-6):265-75. doi: 10.1016/s0090-6980(98)00025-2. [PMID: 9653766]
  • W Cawello, H Schweer, B Dietrich, H W Seyberth, D Albrecht, A Fox, H Hohmuth. Pharmacokinetics of prostaglandin E1 and its main metabolites after intracavernous injection and short-term infusion of prostaglandin E1 in patients with erectile dysfunction. The Journal of urology. 1997 Oct; 158(4):1403-7. doi: NULL. [PMID: 9302131]
  • B Misselwitz, M Bräutigam. A comparative study of the effects of iloprost and PGE1 on pulmonary arterial pressure and edema formation in the isolated perfused rat lung model. Prostaglandins. 1996 Mar; 51(3):179-90. doi: 10.1016/0090-6980(96)00002-0. [PMID: 8848548]
  • D Pallapies, B A Peskar. Effect of prostaglandin (PG) E1 and its initial metabolites on neutrophil-induced inhibition of human platelet aggregation. Thrombosis research. 1993 Aug; 71(3):217-25. doi: 10.1016/0049-3848(93)90096-7. [PMID: 8211888]
  • H Sinzinger, I Virgolini, S R Li, A Gerakakis, P Fitscha, J O'Grady. Increase in in vivo low-density lipoprotein (LDL) receptor binding after PGE1 and 13,14-dihydro-PGE1 treatment in rabbits. Journal of cardiovascular pharmacology. 1993 Mar; 21(3):503-6. doi: 10.1097/00005344-199303000-00023. [PMID: 7681515]
  • H Sinzinger, I Virgolini, A Keiler, G Lupattelli, A Gerakakis, B A Peskar. 13,14-Dihydro-prostaglandin E1 decreases low-density lipoprotein influx into rabbit aorta. European journal of pharmacology. 1992 Aug; 219(1):129-33. doi: 10.1016/0014-2999(92)90590-z. [PMID: 1397039]
  • A Leonhardt, H Schweer, D Wolf, H W Seyberth. Formation of biologically active 13,14-dihydro-prostaglandin E1 during intravenous infusion of prostaglandin E1 in newborns with ductus arteriosus-dependent congenital heart disease. British journal of clinical pharmacology. 1992 Mar; 33(3):323-5. doi: 10.1111/j.1365-2125.1992.tb04044.x. [PMID: 1576056]
  • W H Hesse, G Rudofsky, B A Peskar. [Metabolism of intravenously administered prostaglandin E1 in patients with peripheral arterial occlusive disease]. Wiener klinische Wochenschrift. 1991; 103(18):554-7. doi: NULL. [PMID: 1750222]