Imidazoleacetic acid ribotide (BioDeep_00000005524)

   

human metabolite Endogenous


代谢物信息卡片


2-{1-[(3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-1H-imidazol-4-yl}acetic acid

化学式: C10H15N2O9P (338.05151500000005)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(feces) 2.27%

分子结构信息

SMILES: C(c1cn(cn1)[C@H]1[C@@H]([C@@H]([C@@H](COP(=O)(O)O)O1)O)O)C(=O)O
InChI: InChI=1S/C10H15N2O9P/c13-7(14)1-5-2-12(4-11-5)10-9(16)8(15)6(21-10)3-20-22(17,18)19/h2,4,6,8-10,15-16H,1,3H2,(H,13,14)(H2,17,18,19)/t6-,8-,9-,10-/m1/s1

描述信息

Imidazoleacetic acid ribotide (IAA-RP ) is an endogenous ligand that stimulates imidazol(in)e receptors. Experimental data suggest that IAA-RP may participate in transsynaptic signaling in brain, because it exists in brainstem neurons, exhibits depolarization-induced Ca2+-dependent release from P2 synaptosomal elements, has relatively high affinity for membrane-bound I-R sites, and produces physiological effects on exogenous application. IAA-RP is rapidly metabolized by phosphatases and ecto-5-nucleotidases. (PMID: 15365189) [HMDB]
Imidazoleacetic acid ribotide (IAA-RP) is an endogenous ligand that stimulates imidazol(in)e receptors. Experimental data suggest that IAA-RP may participate in transsynaptic signaling in brain, because it exists in brainstem neurons, exhibits depolarization-induced Ca2+-dependent release from P2 synaptosomal elements, has relatively high affinity for membrane-bound I-R sites, and produces physiological effects on exogenous application. IAA-RP is rapidly metabolized by phosphatases and ecto-5-nucleotidases. (PMID: 15365189).

同义名列表

21 个代谢物同义名

2-{1-[(3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-1H-imidazol-4-yl}acetic acid; {1-[(3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]imidazol-4-yl}acetic acid; 1-beta-delta-Ribofuranosyl-imidazole-4-acetic acid 5-(dihydrogen phosphate); 1-(5-O-phosphono-beta-delta-Ribofuranosyl)-1H-imidazole-4-acetic acid; 1-b-D-Ribofuranosyl-imidazole-4-acetic acid 5-(dihydrogen phosphate); 1-(5-O-phosphono-b-D-Ribofuranosyl)-1H-imidazole-4-acetic acid; 1-beta-delta-Ribofuranosyl-imidazole-4-acetic acid 5-phosphate; 1-b-D-Ribofuranosyl-imidazole-4-acetic acid 5-phosphate; [1-(5-Phosphoribofuranosyl)imidazol-4-yl]acetic acid; [1-(5-Phosphoribosyl)imidazol-4-yl]acetic acid; 1-Ribosylimidazole-4-acetic acid 5-phosphate; 1-(5-Phosphoribosyl)imidazol-4-ylacetic acid; 1-(5-Phosphoribosyl)imidazole-4-acetic acid; [1-(5-Phosphoribosyl)imidazol-4-yl]acetate; 1-(5-Phosphoribosyl)imidazol-4-ylacetate; 1-(5-Phosphoribosyl)imidazole-4-acetate; Imidazole-4-acetic acid ribotide; Imidazoleacetic acid ribotide; Imidazoleacetate ribotide; DTXSID10951514; IAA-RP



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1 个相关的物种来源信息

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