6-oxopiperidine-2-carboxylate (BioDeep_00000054822)

   

human metabolite


代谢物信息卡片


6-hydroxy-2,3,4,5-tetrahydropyridine-2-carboxylic acid

化学式: C6H9NO3 (143.0582404)
中文名称: 6-氧代哌嗪酸, (S)-2-哌啶酮-6-羧酸
谱图信息: 最多检出来源 Homo sapiens(feces) 55.72%

Reviewed

Last reviewed on 2024-09-14.

Cite this Page

6-oxopiperidine-2-carboxylate. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/6-oxopiperidine-2-carboxylate (retrieved 2024-11-21) (BioDeep RN: BioDeep_00000054822). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1CC(C(=O)O)NC(=O)C1
InChI: InChI=1S/C6H9NO3/c8-5-3-1-2-4(7-5)6(9)10/h4H,1-3H2,(H,7,8)(H,9,10)

描述信息

6-Oxopiperidine-2-carboxylic acid, also known as 6-Oxo-pipecolinic acid, or 6-Oxo-piperidine-2-carboxylic acid, is associated with penicillin V in the production on Penicillium chrysogenum fermentations. Analysis of a 13C NMR spectrum of a concentrated broth from Penicillium chrysogenum fermentation revealed the presence of penicillin V and 6-oxo-piperidine-2-carboxylic acid(1) as the principal constituents. The latter lactam, identical to an authentic sample prepared by the cyclization of alpha-aminoadipic acid was present to the extent of 28 mol\\% of penicillin V. The lactam isolated form the broth was nearly racemic, having a slight excess of the L-isomer. This isolation provides further evidence regarding the biosynthetic precursors of the hydrophobic penicillins. (PMID: 6788737

同义名列表

12 个代谢物同义名

6-hydroxy-2,3,4,5-tetrahydropyridine-2-carboxylic acid; 6-Oxopiperidine-2-carboxylic acid; 6-Oxo-2-piperidinecarboxylic acid; 6-Oxopiperidine-2-carboxylate; Cyclic alpha-aminoadipic acid; Cyclic alpha-aminoadipate; Cyclic α-aminoadipic acid; Cyclic a-aminoadipic acid; Cyclic α-aminoadipate; Cyclic a-aminoadipate; Adipo-2,6-lactam; 6-OPCA



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Udo Fh Engelke, Rianne E van Outersterp, Jona Merx, Fred Amg van Geenen, Arno van Rooij, Giel Berden, Marleen Cdg Huigen, Leo Aj Kluijtmans, Tessa Ma Peters, Hilal H Al-Shekaili, Blair R Leavitt, Erik de Vrieze, Sanne Broekman, Erwin van Wijk, Laura A Tseng, Purva Kulkarni, Floris Pjt Rutjes, Jasmin Mecinović, Eduard A Struys, Laura A Jansen, Sidney M Gospe, Saadet Mercimek-Andrews, Keith Hyland, Michèl Aap Willemsen, Levinus A Bok, Clara Dm van Karnebeek, Ron A Wevers, Thomas J Boltje, Jos Oomens, Jonathan Martens, Karlien Lm Coene. Untargeted metabolomics and infrared ion spectroscopy identify biomarkers for pyridoxine-dependent epilepsy. The Journal of clinical investigation. 2021 08; 131(15):. doi: 10.1172/jci148272. [PMID: 34138754]
  • R J Roberts. Bacterial diseases of farmed fishes. Society for Applied Bacteriology symposium series. 1976; 4(?):55-62. doi: NULL. [PMID: 5781]