N-Acetyl-L-glutamyl 5-phosphate (BioDeep_00000005420)

 

Secondary id: BioDeep_00001869416

human metabolite Endogenous


代谢物信息卡片


(2S)-2-acetamido-5-oxo-5-(Phosphonooxy)pentanoic acid

化学式: C7H12NO8P (269.0300522)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(natural_products) 0.2%

分子结构信息

SMILES: CC(=O)NC(CCC(=O)OP(=O)(O)O)C(=O)O
InChI: InChI=1S/C7H12NO8P/c1-4(9)8-5(7(11)12)2-3-6(10)16-17(13,14)15/h5H,2-3H2,1H3,(H,8,9)(H,11,12)(H2,13,14,15)/t5-/m0/s1

描述信息

N-Acetyl-L-glutamyl 5-phosphate is an intermediate in urea cycle and metabolism of amino groups. The enzyme N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38] catalyzes the conversion of this metabolite into N-acetyl-L-glutamate 5-semialdehyde. This reaction is irreversible and occurs in the mitochondria. (BiGG database) [HMDB]
N-Acetyl-L-glutamyl 5-phosphate is an intermediate in urea cycle and metabolism of amino groups. The enzyme N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38] catalyzes the conversion of this metabolite into N-acetyl-L-glutamate 5-semialdehyde. This reaction is irreversible and occurs in the mitochondria. (BiGG database).

同义名列表

13 个代谢物同义名

(2S)-2-acetamido-5-oxo-5-(Phosphonooxy)pentanoic acid; (2S)-2-acetamido-5-oxo-5-(Phosphonooxy)pentanoate; N-Acetyl-5-oxo-5-(phosphonooxy)-L-norvaline; N-Acetyl-L-glutamic acid 5-phosphoric acid; N-Acetyl-L-glutamyl 5-phosphoric acid; N-Acetyl-5-glutamyl phosphoric acid; N-Acetyl-gamma-L-glutamyl phosphate; N-Acetyl-gamma-glutamyl phosphate; N-Acetyl-L-glutamate 5-phosphate; N-Acetyl-L-glutamyl 5-phosphate; N-Acetyl-5-glutamyl phosphate; N-Acetyl-γ-glutamyl phosphate; SCHEMBL22352571



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(0)

代谢反应

505 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(7)

WikiPathways(0)

Plant Reactome(492)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(6)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Yufei Wang, Zeliang Chen, Feng Qiao, Tianyi Ying, Jing Yuan, Zhijun Zhong, Lei Zhou, Xinying Du, Zhoujia Wang, Jin Zhao, Shicun Dong, Leili Jia, Xitong Yuan, Ruifu Yang, Yansong Sun, Liuyu Huang. Comparative proteomics analyses reveal the virB of B. melitensis affects expression of intracellular survival related proteins. PloS one. 2009; 4(4):e5368. doi: 10.1371/journal.pone.0005368. [PMID: 19401764]
  • Frances M Dupont. Metabolic pathways of the wheat (Triticum aestivum) endosperm amyloplast revealed by proteomics. BMC plant biology. 2008 Apr; 8(?):39. doi: 10.1186/1471-2229-8-39. [PMID: 18419817]
  • Tsuyoshi Nonaka, Akiko Kita, Jun Miura-Ohnuma, Etsuko Katoh, Noritoshi Inagaki, Toshimasa Yamazaki, Kunio Miki. Crystal structure of putative N-acetyl-gamma-glutamyl-phosphate reductase (AK071544) from rice (Oryza sativa). Proteins. 2005 Dec; 61(4):1137-40. doi: 10.1002/prot.20679. [PMID: 16240442]
  • S Ferraioli, R Taté, E Caputo, A Lamberti, A Riccio, E J Patriarca. The Rhizobium etli argC gene is essential for Arginine biosynthesis and nodulation of Phaseolus vulgaris. Molecular plant-microbe interactions : MPMI. 2001 Feb; 14(2):250-4. doi: 10.1094/mpmi.2001.14.2.250. [PMID: 11204789]