2-tert-Butyl-4-hydroxyanisole (BioDeep_00000053901)

   

human metabolite


代谢物信息卡片


2-(1,1-Dimethylethyl)-4-hydroxyanisole

化学式: C11H16O2 (180.115)
中文名称: 2-叔丁基-4-羟基茴香醚
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)(C)C1=C(C=CC(=C1)O)OC
InChI: InChI=1S/C11H16O2/c1-11(2,3)9-7-8(12)5-6-10(9)13-4/h5-7,12H,1-4H3

描述信息

2-tert-Butyl-4-hydroxyanisole is an ingredient in butylated hydroxyanisole. Butylated hydroxyanisole (BHA) is an antioxidant consisting of a mixture of two isomeric organic compounds, 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole. It is prepared from 4-methoxyphenol and isobutylene. It is a waxy solid used as a food additive with the E number E320. The primary use for BHA is as an antioxidant and preservative in food, food packaging, animal feed, cosmetics, rubber, and petroleum products. BHA also is commonly used in medicines, such as isotretinoin, lovastatin, and simvastatin, among others. (Wikipedia)
C26170 - Protective Agent > C275 - Antioxidant

同义名列表

13 个代谢物同义名

2-(1,1-Dimethylethyl)-4-hydroxyanisole; 3-(1,1-Dimethylethyl)-4-methoxyphenol; 2-tert-Butyl-4-hydroxyanisole; 4-Hydroxy-2-tert-butylanisole; 2-Tert-butyl-p-hydroxyanisole; m-Tert-butyl-p-methoxyphenol; p-Methoxy-m-tert-butylphenol; 4-Methoxy-5-tert-butylphenol; 3-tert-butyl-4-methoxyphenol; 4-Methoxy-3-tert-butylphenol; 2-BHA; TBMP; Phoratoxin B (reduced) 46



数据库引用编号

4 个数据库交叉引用编号

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相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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INOH(0)

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1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Zhendong Sun, Xiaoxi Yang, Qian S Liu, Chuanhai Li, Qunfang Zhou, Heidelore Fiedler, Chunyang Liao, Jianqing Zhang, Guibin Jiang. Butylated hydroxyanisole isomers induce distinct adipogenesis in 3T3-L1 cells. Journal of hazardous materials. 2019 11; 379(?):120794. doi: 10.1016/j.jhazmat.2019.120794. [PMID: 31238218]
  • Barbara Tóth, Judit Hohmann, Andrea Vasas. Phenanthrenes: A Promising Group of Plant Secondary Metabolites. Journal of natural products. 2018 03; 81(3):661-678. doi: 10.1021/acs.jnatprod.7b00619. [PMID: 29280630]
  • Carla Barberis, Andrea Astoreca, María Guillermina Fernandez-Juri, Ana María Dalcero, Carina Magnoli. Effect of antioxidant mixtures on growth and ochratoxin a production of Aspergillus section Nigri species under different water activity conditions on peanut meal extract agar. Toxins. 2010 06; 2(6):1399-413. doi: 10.3390/toxins2061399. [PMID: 22069644]
  • S K Chaube, Sabana Khatun, S K Misra, T G Shrivastav. Calcium ionophore-induced egg activation and apoptosis are associated with the generation of intracellular hydrogen peroxide. Free radical research. 2008 Mar; 42(3):212-20. doi: 10.1080/10715760701868352. [PMID: 18344115]
  • J M Menter, A A Etemadi, W Chapman, T D Hollins, I Willis. In vivo depigmentation by hydroxybenzene derivatives. Melanoma research. 1993 Dec; 3(6):443-9. doi: 10.1097/00008390-199311000-00007. [PMID: 8161883]
  • M Hirose, A Hagiwara, K Inoue, N Ito, H Kaneko, K Saito, H Matsunaga, N Isobe, A Yoshitake, J Miyamoto. Metabolism of 2- and 3-tert-butyl-4-hydroxyanisole in the rat (III): Metabolites in the urine and feces. Toxicology. 1988 Dec; 53(1):33-43. doi: 10.1016/0300-483x(88)90234-x. [PMID: 3201475]
  • G Hocman. Chemoprevention of cancer: phenolic antioxidants (BHT, BHA). The International journal of biochemistry. 1988; 20(7):639-51. doi: 10.1016/0020-711x(88)90158-9. [PMID: 3053283]
  • M Hirose, A Hagiwara, K Inoue, T Sakata, N Ito, H Kaneko, A Yoshitake, J Miyamoto. Metabolism of 2- and 3-tert-butyl-4-hydroxyanisole (2- and 3-BHA) in the rat (I): Excretion of BHA in urine, feces and expired air and distribution of BHA in the main organs. Toxicology. 1987 Feb; 43(2):139-47. doi: 10.1016/0300-483x(87)90004-7. [PMID: 3810657]