dIDP (BioDeep_00000004672)

 

Secondary id: BioDeep_00001869089

human metabolite Endogenous


代谢物信息卡片


{[hydroxy({[(2R,3S,5R)-3-hydroxy-5-(6-oxo-6,9-dihydro-3H-purin-9-yl)oxolan-2-yl]methoxy})phosphoryl]oxy}phosphonic acid

化学式: C10H14N4O10P2 (412.0185164)
中文名称:
谱图信息: 最多检出来源 Macaca mulatta(otcml) 4.35%

分子结构信息

SMILES: C1C(C(OC1N2C=NC3=C2N=CNC3=O)COP(=O)(O)OP(=O)(O)O)O
InChI: InChI=1S/C10H14N4O10P2/c15-5-1-7(14-4-13-8-9(14)11-3-12-10(8)16)23-6(5)2-22-26(20,21)24-25(17,18)19/h3-7,15H,1-2H2,(H,20,21)(H,11,12,16)(H2,17,18,19)/t5-,6+,7+/m0/s1

描述信息

dIDP (deoxyinoside diphosphate) is a nucleoside. Deoxyinosine diphosphate appears in the urine of patients with purine metabolism abnormalities in purine nucleoside phosphorylase deficiency(OMIM 164050) [HMDB]
dIDP (deoxyinoside diphosphate) is a nucleoside. Deoxyinosine diphosphate appears in the urine of patients with purine metabolism abnormalities in purine nucleoside phosphorylase deficiency(OMIM 164050).

同义名列表

7 个代谢物同义名

{[hydroxy({[(2R,3S,5R)-3-hydroxy-5-(6-oxo-6,9-dihydro-3H-purin-9-yl)oxolan-2-yl]methoxy})phosphoryl]oxy}phosphonic acid; 2-Deoxyinosine 5-diphosphoric acid; 2-Deoxyinosine-5-diphosphoric acid; 2-Deoxyinosine 5-diphosphate; 2-Deoxyinosine-5-diphosphate; 2-Deoxyinosine; dIDP



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

3 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(1)

Plant Reactome(0)

INOH(2)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

5 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Pei Chen, Wei Li, Qin Li, Yinghua Wang, Zhenguo Li, Yefeng Ni, Kazuo Koike. Identification and quantification of nucleosides and nucleobases in Geosaurus and Leech by hydrophilic-interaction chromatography. Talanta. 2011 Sep; 85(3):1634-41. doi: 10.1016/j.talanta.2011.06.056. [PMID: 21807233]
  • Koli Taghizadeh, Jose L McFaline, Bo Pang, Matthew Sullivan, Min Dong, Elaine Plummer, Peter C Dedon. Quantification of DNA damage products resulting from deamination, oxidation and reaction with products of lipid peroxidation by liquid chromatography isotope dilution tandem mass spectrometry. Nature protocols. 2008; 3(8):1287-98. doi: 10.1038/nprot.2008.119. [PMID: 18714297]
  • Bo Pang, Xinfeng Zhou, Hongbin Yu, Min Dong, Koli Taghizadeh, John S Wishnok, Steven R Tannenbaum, Peter C Dedon. Lipid peroxidation dominates the chemistry of DNA adduct formation in a mouse model of inflammation. Carcinogenesis. 2007 Aug; 28(8):1807-13. doi: 10.1093/carcin/bgm037. [PMID: 17347141]
  • Soo Jin Lee, Han Sung Hwang, Bit Na Rae Kim, Min A Kim, Jae Wook Lee, Yong Won Park, Young Han Kim. Changes in serum adenosine deaminase activity during normal pregnancy. Journal of Korean medical science. 2007 Aug; 22(4):718-21. doi: 10.3346/jkms.2007.22.4.718. [PMID: 17728516]
  • Maciej Szuwart, Elzbieta Starzyńska, Małgorzata Pietrowska-Borek, Andrzej Guranowski. Calcium-stimulated guanosine--inosine nucleosidase from yellow lupin (Lupinus luteus). Phytochemistry. 2006 Jul; 67(14):1476-85. doi: 10.1016/j.phytochem.2006.05.021. [PMID: 16820181]
  • Raphaelle Fanciullino, Sarah Giacometti, Claude Aubert, Frederic Fina, Pierre-Marie Martin, Philippe Piccerelle, Joseph Ciccolini. Development of stealth liposome formulation of 2'-deoxyinosine as 5-fluorouracil modulator: in vitro and in vivo study. Pharmaceutical research. 2005 Dec; 22(12):2051-7. doi: 10.1007/s11095-005-8355-9. [PMID: 16222443]