Primin (BioDeep_00000004091)

   

PANOMIX_OTCML-2023 Volatile Flavor Compounds natural product


代谢物信息卡片


2,5-Cyclohexadiene-1,4-dione, 2-methoxy-6-pentyl-

化学式: C12H16O3 (208.1099386)
中文名称: 樱草素, 异兰, 异索兰
谱图信息: 最多检出来源 Viridiplantae(plant) 8.09%

Reviewed

Last reviewed on 2024-06-29.

Cite this Page

Primin. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/primin (retrieved 2024-11-22) (BioDeep RN: BioDeep_00000004091). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CCCCCC1=CC(=O)C=C(C1=O)OC
InChI: InChI=1S/C12H16O3/c1-3-4-5-6-9-7-10(13)8-11(15-2)12(9)14/h7-8H,3-6H2,1-2H3

描述信息

Primin is a 1,4-benzoquinone having a methoxy substituent at the 2-position and a pentyl substituent at the 6-position. It has a role as a hapten, a metabolite, an antimicrobial agent, an antifeedant and an allergen.
Primin is a natural product found in Miconia eriodonta, Cophinforma mamane, and other organisms with data available.
See also: Primula veris flower (part of).
A 1,4-benzoquinone having a methoxy substituent at the 2-position and a pentyl substituent at the 6-position.

Primin. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=15121-94-5 (retrieved 2024-06-29) (CAS RN: 15121-94-5). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

同义名列表

11 个代谢物同义名

2,5-Cyclohexadiene-1,4-dione, 2-methoxy-6-pentyl-; 2-methoxy-6-pentyl-2,5-cyclohexadiene-1,4-dione; 2-methoxy-6-pentylcyclohexa-2,5-diene-1,4-dione; 2-methoxy-6-n-pentyl-1,4-benzoquinone; 2-Methoxy-6-pentyl-1,4-benzoquinone; 2-methoxy-6-n-pentyl-p-benzoquinone; p-Benzoquinone, 2-methoxy-6-pentyl-; 2-Methoxy-6-phentyl-p-benzochinone; 2-methoxy-6-pentylbenzoquinone; Primin; Primin



数据库引用编号

32 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

75 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Miroslav Sisa, Marcela Dvorakova, Veronika Temml, Veronika Jarosova, Tomas Vanek, Premysl Landa. Synthesis, inhibitory activity and in silico docking of dual COX/5-LOX inhibitors with quinone and resorcinol core. European journal of medicinal chemistry. 2020 Oct; 204(?):112620. doi: 10.1016/j.ejmech.2020.112620. [PMID: 32738413]
  • Alisson Bigolin, Mariana F Maioral, Natália M Stefanes, Gabriele A Zatelli, Ana C Philippus, Miriam de B Falkenberg, Maria C Santos-Silva. Cytotoxic mechanisms of primin, a natural quinone isolated from Eugenia hiemalis, on hematological cancer cell lines. Anti-cancer drugs. 2020 08; 31(7):709-717. doi: 10.1097/cad.0000000000000937. [PMID: 32639281]
  • Flávia Pereira Dias Viegas, Patrícia Ferreira Espuri, Josidel Conceição Oliver, Naiara Chaves Silva, Amanda Latércia Tranches Dias, Marcos José Marques, Marisi Gomes Soares. Leishmanicidal and antimicrobial activity of primin and primin-containing extracts from Miconia willdenowii. Fitoterapia. 2019 Oct; 138(?):104297. doi: 10.1016/j.fitote.2019.104297. [PMID: 31404617]
  • Lorenzo Bongiorni, Andrea Prodi, Francesca Rui, Anna Belloni Fortina, Maria T Corradin, Francesca Larese Filon. Primin sensitization in north-eastern Italy: a temporal trend from 1996 to 2012. Contact dermatitis. 2015 Aug; 73(2):108-12. doi: 10.1111/cod.12385. [PMID: 25799880]
  • Premysl Landa, Zsofia Kutil, Veronika Temml, Jan Malik, Ladislav Kokoska, Ute Widowitz, Marie Pribylova, Marcela Dvorakova, Petr Marsik, Daniela Schuster, Rudolf Bauer, Tomas Vanek. Inhibition of in vitro leukotriene B4 biosynthesis in human neutrophil granulocytes and docking studies of natural quinones. Natural product communications. 2013 Jan; 8(1):105-8. doi: . [PMID: 23472470]
  • Evy Paulsen, Lars P Christensen, Klaus Ejner Andersen. Miconidin and miconidin methyl ether from Primula obconica Hance: new allergens in an old sensitizer. Contact dermatitis. 2006 Oct; 55(4):203-9. doi: 10.1111/j.1600-0536.2006.00910.x. [PMID: 16958917]
  • Vinod K Sharma, Gomathy Sethuraman, Taru Garg, Kaushal K Verma, M Ramam. Patch testing with the Indian standard series in New Delhi. Contact dermatitis. 2004 Nov; 51(5-6):319-21. doi: 10.1111/j.0105-1873.2004.0459k.x. [PMID: 15606668]
  • M Connolly, J Mc Cune, E Dauncey, C R Lovell. Primula obconica--is contact allergy on the decline?. Contact dermatitis. 2004 Oct; 51(4):167-71. doi: 10.1111/j.0105-1873.2004.00427.x. [PMID: 15500665]
  • A A Gunatilaka, J M Berger, R Evans, J S Miller, J H Wisse, K M Neddermann, I Bursuker, D G Kingston. Isolation, synthesis, and structure-activity relationships of bioactive benzoquinones from Miconia lepidota from the Suriname rainforest. Journal of natural products. 2001 Jan; 64(1):2-5. doi: 10.1021/np000219r. [PMID: 11170656]
  • L P Christensen, E Larsen. Primin-free Primula obconica plants available. Contact dermatitis. 2000 Jul; 43(1):45-6. doi: ". [PMID: 10902592]
  • L P Christensen, E Larsen. Direct emission of the allergen primin from intact Primula obconica plants. Contact dermatitis. 2000 Mar; 42(3):149-53. doi: 10.1034/j.1600-0536.2000.042003149.x. [PMID: 10727165]
  • M Krebs, L P Christensen. 2-methoxy-6-pentyl-1,4-dihydroxybenzene (miconidin) from Primula obconica: a possible allergen?. Contact dermatitis. 1995 Aug; 33(2):90-3. doi: 10.1111/j.1600-0536.1995.tb00507.x. [PMID: 8549150]
  • B M Hausen, H Heitsch, B Borrmann, D Koch, R Rathmann, B Richter, W A König. Structure-activity relationships in allergic contact dermatitis (I). Studies on the influence of side-chain length with derivatives of primin. Contact dermatitis. 1995 Jul; 33(1):12-6. doi: 10.1111/j.1600-0536.1995.tb00440.x. [PMID: 7493455]
  • E Paulsen. [Primula eczema--well-known and overlooked]. Ugeskrift for laeger. 1994 Feb; 156(8):1147-8. doi: . [PMID: 8116095]