Glycodeoxycholic acid (BioDeep_00000408599)
natural product Bile acids
代谢物信息卡片
化学式: C26H43NO5 (449.31410680000005)
中文名称: 甘氨脱氧胆酸
谱图信息:
最多检出来源 Homo sapiens(bile_acids) 46.08%
Last reviewed on 2024-07-19.
Cite this Page
Glycodeoxycholic acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/glycodeoxycholic_acid (retrieved
2024-11-22) (BioDeep RN: BioDeep_00000408599). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
分子结构信息
SMILES: CC(CCC(=O)NCC(=O)O)C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C
InChI: InChI=1S/C26H43NO5/c1-15(4-9-23(30)27-14-24(31)32)19-7-8-20-18-6-5-16-12-17(28)10-11-25(16,2)21(18)13-22(29)26(19,20)3/h15-22,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32)/t15-,16?,17-,18+,19-,20+,21+,22+,25+,26-/m1/s1
描述信息
CONFIDENCE standard compound; INTERNAL_ID 54
同义名列表
数据库引用编号
14 个数据库交叉引用编号
- PubChem: 18602029
- MeSH: Glycodeoxycholic Acid
- MoNA: CCMSLIB00005435459
- MoNA: CCMSLIB00005435460
- MoNA: CCMSLIB00005435461
- MoNA: CCMSLIB00005435519
- MoNA: CCMSLIB00005435520
- MoNA: CCMSLIB00005435521
- MoNA: CCMSLIB00005435522
- MoNA: CCMSLIB00005435523
- MoNA: RP005403
- MoNA: RP005402
- MoNA: RP005401
- RefMet: Glycodeoxycholic acid
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Cuitong Wang, Bin Cheng, Wei Wei, Lanlan Gui, Wushuang Zeng, Yutong Wang, Yixuan Wang, Qi Chen, Liang Xu, Jia Miao, Ke Lan. Comparison of 1Beta- and 5Beta-hydroxylation of Deoxycholate and Glycodeoxycholate as In Vitro Index Reactions for Cytochrome P450 3A Activities.
Drug metabolism and disposition: the biological fate of chemicals.
2024 Jan; 52(2):126-134. doi:
10.1124/dmd.123.001513. [PMID: 38050044] - Sławomira Drzymała-Czyż, Krzysztof Dziedzic, Artur Szwengiel, Patrycja Krzyżanowska-Jankowska, Jan K Nowak, Agata Nowicka, Raisa Aringazina, Sylwia Drzymała, Nataliya Kashirskaya, Jarosław Walkowiak. Serum bile acids in cystic fibrosis patients - glycodeoxycholic acid as a potential marker of liver disease.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.
2022 Jan; 54(1):111-117. doi:
10.1016/j.dld.2021.06.034. [PMID: 34305015] - Phylyne van Rijs, Vincenzo Fogliano. Roasting carob flour decreases the capacity to bind glycoconjugates of bile acids.
Food & function.
2020 Jul; 11(7):5924-5932. doi:
10.1039/d0fo01158d. [PMID: 32638775] - Li-Na Yang, Jing Wen, Yi Sun, Jia-Jia Liang, Wei-Hua Zheng, Li-Li Zhang, Yu-Jie Zhou, Zhi-Li Xiong. [Metabonomic study on the anti-liver injury effect of Si-Ni-San on rats by using UPLC-MS/MS].
Yao xue xue bao = Acta pharmaceutica Sinica.
2014 Mar; 49(3):368-73. doi:
NULL. [PMID: 24961109] - Filipe M Coreta-Gomes, Winchil L C Vaz, Emeric Wasielewski, Carlos F G C Geraldes, Maria João Moreno. Quantification of cholesterol solubilized in bile salt micellar aqueous solutions using (13)C nuclear magnetic resonance.
Analytical biochemistry.
2012 Aug; 427(1):41-8. doi:
10.1016/j.ab.2012.04.028. [PMID: 22569559] - Yong Zhou, Elizabeth J Dial, Rand Doyen, Lenard M Lichtenberger. Effect of indomethacin on bile acid-phospholipid interactions: implication for small intestinal injury induced by nonsteroidal anti-inflammatory drugs.
American journal of physiology. Gastrointestinal and liver physiology.
2010 May; 298(5):G722-31. doi:
10.1152/ajpgi.00387.2009. [PMID: 20203063] - Femke Lutgendorff, Lena M Trulsson, L Paul van Minnen, Ger T Rijkers, Harro M Timmerman, Lennart E Franzén, Hein G Gooszen, Louis M A Akkermans, Johan D Söderholm, Per A Sandström. Probiotics enhance pancreatic glutathione biosynthesis and reduce oxidative stress in experimental acute pancreatitis.
American journal of physiology. Gastrointestinal and liver physiology.
2008 Nov; 295(5):G1111-21. doi:
10.1152/ajpgi.00603.2007. [PMID: 18832452] - Frank Axel Wenger, Maik Kilian, Ina Heukamp, Thomas Foitzik, Christoph Andreas Jacobi, Hans Guski, Ingolf Schimke, Joachim Michael Müller. Effects of octreotide in acute hemorrhagic necrotizing pancreatitis in rats.
Journal of gastroenterology and hepatology.
2007 Nov; 22(11):1872-6. doi:
10.1111/j.1440-1746.2006.04627.x. [PMID: 17914962] - K Fadden, M J Hill, E Latymer, G Low, R W Owen. Steroid metabolism along the gastrointestinal tract of the cannulated pig.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP).
1999 Feb; 8(1):35-40. doi:
10.1097/00008469-199902000-00005. [PMID: 10091041] - E A Trautwein, D Rieckhoff, H F Erbersdobler. Dietary inulin lowers plasma cholesterol and triacylglycerol and alters biliary bile acid profile in hamsters.
The Journal of nutrition.
1998 Nov; 128(11):1937-43. doi:
10.1093/jn/128.11.1937. [PMID: 9808646] - J Wu, S S Peng. Comparison of hypolipidemic effect of refined konjac meal with several common dietary fibers and their mechanisms of action.
Biomedical and environmental sciences : BES.
1997 Mar; 10(1):27-37. doi:
NULL. [PMID: 9099424] - G Salvioli, E Gaetti, R Panini, R Lugli, J M Pradelli. Different resistance of mammalian red blood cells to hemolysis by bile salts.
Lipids.
1993 Nov; 28(11):999-1003. doi:
10.1007/bf02537121. [PMID: 8277831] - D W Rattner, L M Napolitano, J Corsetti, C Compton, G G Stanford, A L Warshaw, B Chernow. Hypocalcemia in experimental pancreatitis occurs independently of changes in serum nonesterified fatty acid levels.
International journal of pancreatology : official journal of the International Association of Pancreatology.
1990 Jun; 6(4):249-62. doi:
10.1007/bf02924404. [PMID: 1698894] - K Opleta, E V O'Loughlin, E A Shaffer, J Hayden, M Hollenberg, D G Gall. Effect of epidermal growth factor on growth and postnatal development of the rabbit liver.
The American journal of physiology.
1987 Nov; 253(5 Pt 1):G622-6. doi:
10.1152/ajpgi.1987.253.5.g622. [PMID: 3500648] - A K Batta, S Shefer, G Salen. Thin-layer chromatographic separation of conjugates of ursodeoxycholic acid from those of litho-, chenodeoxy-, deoxy-, and cholic acids.
Journal of lipid research.
1981 May; 22(4):712-4. doi:
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Biochimica et biophysica acta.
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10.1016/0005-2736(81)90531-9. [PMID: 7213693]