Fumonisin B3 (BioDeep_00000408561)

   

natural product


代谢物信息卡片


2-[2-[(5R,6R,7S,9S,11R,18S,19R)-19-amino-6-(3,4-dicarboxybutanoyloxy)-11,18-dihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid

化学式: C34H59NO14 (705.3935354)
中文名称: 烟曲霉毒素 B3
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCC(C)C(C(CC(C)CC(CCCCCCC(C(C)N)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O
InChI: InChI=1S/C34H59NO14/c1-5-6-11-21(3)32(49-31(43)19-24(34(46)47)17-29(40)41)27(48-30(42)18-23(33(44)45)16-28(38)39)15-20(2)14-25(36)12-9-7-8-10-13-26(37)22(4)35/h20-27,32,36-37H,5-19,35H2,1-4H3,(H,38,39)(H,40,41)(H,44,45)(H,46,47)/t20-,21+,22+,23?,24?,25+,26-,27-,32+/m0/s1

描述信息

D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins
D009676 - Noxae > D011042 - Poisons > D037341 - Fumonisins
D009676 - Noxae > D002273 - Carcinogens
CONFIDENCE isolated standard

同义名列表

2 个代谢物同义名

Fumonisin B3; 2-[2-[(5R,6R,7S,9S,11R,18S,19R)-19-amino-6-(3,4-dicarboxybutanoyloxy)-11,18-dihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

9 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • András Szabó, Szabolcs Nagy, Omeralfaroug Ali, Zsolt Gerencsér, Miklós Mézes, Krisztián Milán Balogh, Tibor Bartók, Levente Horváth, Aziz Mouhanna, Melinda Kovács. A 65-Day Fumonisin B Exposure at High Dietary Levels Has Negligible Effects on the Testicular and Spermatological Parameters of Adult Rabbit Bucks. Toxins. 2021 03; 13(4):. doi: 10.3390/toxins13040237. [PMID: 33806221]
  • András Szabó, Omeralfaroug Ali, Katalin Lóki, Krisztián Balogh, Miklós Mézes, Tibor Bartók, Levente Horváth, Melinda Kovács. Orally Administered Fumonisins Affect Porcine Red Cell Membrane Sodium Pump Activity and Lipid Profile Without Apparent Oxidative Damage. Toxins. 2020 05; 12(5):. doi: 10.3390/toxins12050318. [PMID: 32408599]
  • Fenghua Li, Dafeng Jiang, Fengjia Zheng, Jindong Chen, Wei Li. Fumonisins B₁, B₂ and B₃ in corn products, wheat flour and corn oil marketed in Shandong province of China. Food additives & contaminants. Part B, Surveillance. 2015; 8(3):169-74. doi: 10.1080/19393210.2015.1028480. [PMID: 25777369]
  • Olga Torres, Jorge Matute, Janee Gelineau-van Waes, Joyce R Maddox, Simon G Gregory, Allison E Ashley-Koch, Jency L Showker, Nicholas C Zitomer, Kenneth A Voss, Ronald T Riley. Urinary fumonisin B1 and estimated fumonisin intake in women from high- and low-exposure communities in Guatemala. Molecular nutrition & food research. 2014 May; 58(5):973-83. doi: 10.1002/mnfr.201300481. [PMID: 24375966]
  • Zheng Han, Yiping Ren, Xuesong Liu, Lianjun Luan, Yongjiang Wu. A reliable isotope dilution method for simultaneous determination of fumonisins B1, B2 and B3 in traditional Chinese medicines by ultra-high-performance liquid chromatography-tandem mass spectrometry. Journal of separation science. 2010 Sep; 33(17-18):2723-33. doi: 10.1002/jssc.201000423. [PMID: 20730841]
  • Jens C Frisvad, Jørn Smedsgaard, Robert A Samson, Thomas O Larsen, Ulf Thrane. Fumonisin B2 production by Aspergillus niger. Journal of agricultural and food chemistry. 2007 Nov; 55(23):9727-32. doi: 10.1021/jf0718906. [PMID: 17929891]
  • Chenglan Liu, Wenna Xu, Fengmao Liu, Shuren Jiang. Fumonisins production by Fusarium proliferatum strains isolated from asparagus crown. Mycopathologia. 2007 Sep; 164(3):127-34. doi: 10.1007/s11046-007-9017-8. [PMID: 17629787]
  • R T Riley, O A Torres, E Palencia. International shipping of fumonisins from maize extracts on C18 sorbent. Food additives and contaminants. 2006 Aug; 23(8):826-32. doi: 10.1080/02652030600699650. [PMID: 16807208]
  • Quenton Kritzinger, Theresa A S Aveling, Walter F O Marasas, John P Rheeder, Liana Van Der Westhuizen, Gordon S Shephard. Mycoflora and fumonisin mycotoxins associated with cowpea [Vigna unguiculata (L.) Walp] seeds. Journal of agricultural and food chemistry. 2003 Apr; 51(8):2188-92. doi: 10.1021/jf026121v. [PMID: 12670154]
  • Paul C Howard, Letha H Couch, Ralph E Patton, Robert M Eppley, Daniel R Doerge, Mona I Churchwell, M Matilde Marques, Carlin V Okerberg. Comparison of the toxicity of several fumonisin derivatives in a 28-day feeding study with female B6C3F(1) mice. Toxicology and applied pharmacology. 2002 Dec; 185(3):153-65. doi: 10.1006/taap.2002.9529. [PMID: 12498732]
  • A E Desjardins, G P Munkvold, R D Plattner, R H Proctor. FUM1--a gene required for fumonisin biosynthesis but not for maize ear rot and ear infection by Gibberella moniliformis in field tests. Molecular plant-microbe interactions : MPMI. 2002 Nov; 15(11):1157-64. doi: 10.1094/mpmi.2002.15.11.1157. [PMID: 12423021]
  • H K Abbas, R D Cartwright, W Xie, C J Mirocha, J L Richard, T J Dvorak, G L Sciumbato, W T Shier. Mycotoxin production by Fusarium proliferatum isolates from rice with Fusarium sheath rot disease. Mycopathologia. 1999; 147(2):97-104. doi: 10.1023/a:1007147813326. [PMID: 10967968]
  • K A Voss, R D Plattner, R T Riley, F I Meredith, W P Norred. In vivo effects of fumonisin B1-producing and fumonisin B1-nonproducing Fusarium moniliforme isolates are similar: fumonisins B2 and B3 cause hepato- and nephrotoxicity in rats. Mycopathologia. 1998; 141(1):45-58. doi: 10.1023/a:1006810916344. [PMID: 9725030]
  • M K Morgan, J J Schroeder, G E Rottinghaus, D C Powell, S J Bursian, R J Aulerich. Dietary fumonisins disrupt sphingolipid metabolism in mink and increase the free sphinganine to sphingosine ratio in urine but not in hair. Veterinary and human toxicology. 1997 Dec; 39(6):334-6. doi: NULL. [PMID: 9397500]
  • D C Powell, S J Bursian, C R Bush, J A Render, G E Rottinghaus, R J Aulerich. Effects of dietary exposure to fumonisins from Fusarium moniliforme culture material (M-1325) on the reproductive performance of female mink. Archives of environmental contamination and toxicology. 1996 Aug; 31(2):286-92. doi: 10.1007/bf00212379. [PMID: 8781082]
  • J F Leslie, W F Marasas, G S Shephard, E W Sydenham, S Stockenström, P G Thiel. Duckling toxicity and the production of fumonisin and moniliformin by isolates in the A and E mating populations of Gibberella fujikuroi (Fusarium moniliforme). Applied and environmental microbiology. 1996 Apr; 62(4):1182-7. doi: 10.1128/aem.62.4.1182-1187.1996. [PMID: 8919779]
  • C J Mirocha, J Chen, W Xie, Y Xu, H K Abbas, L R Hogge. Biosynthesis of fumonisin and aal derivatives by Alternaria and Fusarium in laboratory culture. Advances in experimental medicine and biology. 1996; 392(?):213-24. doi: 10.1007/978-1-4899-1379-1_19. [PMID: 8850619]
  • J C Restum, S J Bursian, M Millerick, J A Render, A H Merrill, E Wang, G E Rottinghaus, R J Aulerich. Chronic toxicity of fumonisins from Fusarium moniliforme culture material (M-1325) to mink. Archives of environmental contamination and toxicology. 1995 Nov; 29(4):545-50. doi: 10.1007/bf00208387. [PMID: 7574884]
  • T S Edrington, C A Kamps-Holtzapple, R B Harvey, L F Kubena, M H Elissalde, G E Rottinghaus. Acute hepatic and renal toxicity in lambs dosed with fumonisin-containing culture material. Journal of animal science. 1995 Feb; 73(2):508-15. doi: 10.2527/1995.732508x. [PMID: 7601785]
  • J D Miller, M E Savard, S Rapior. Production and purification of fumonisins from a stirred jar fermenter. Natural toxins. 1994; 2(6):354-9. doi: ". [PMID: 7704448]
  • H K Abbas, W C Gelderblom, M E Cawood, W T Shier. Biological activities of fumonisins, mycotoxins from Fusarium moniliforme, in jimsonweed (Datura stramonium L.) and mammalian cell cultures. Toxicon : official journal of the International Society on Toxinology. 1993 Mar; 31(3):345-53. doi: 10.1016/0041-0101(93)90152-9. [PMID: 8470138]
  • J I Azcona-Olivera, M M Abouzied, R D Plattner, W P Norred, J J Pestka. Generation of antibodies reactive with fumonisins B1, B2, and B3 by using cholera toxin as the carrier-adjuvant. Applied and environmental microbiology. 1992 Jan; 58(1):169-73. doi: 10.1128/aem.58.1.169-173.1992. [PMID: 1539971]