Piperic acid (BioDeep_00000407586)

   

natural product


代谢物信息卡片


(2E,4Z)-5-(2H-1,3-benzodioxol-5-yl)penta-2,4-dienoic acid

化学式: C12H10O4 (218.057906)
中文名称: 5-(3,4-亚甲基二氧苯基)-2,4-戊二烯酸
谱图信息: 最多检出来源 Chinese Herbal Medicine(natural_products) 66.67%

分子结构信息

SMILES: C1OC2=C(O1)C=C(C=C2)C=CC=CC(=O)O
InChI: InChI=1S/C12H10O4/c13-12(14)4-2-1-3-9-5-6-10-11(7-9)16-8-15-10/h1-7H,8H2,(H,13,14)

描述信息

同义名列表

11 个代谢物同义名

(E,E)-Piperic Acid; Piperic acid; (2E,4Z)-5-(2H-1,3-benzodioxol-5-yl)penta-2,4-dienoic acid; 2,4-Pentadienoic acid, 5-(1,3-benzodioxol-5-yl)- (9ci); 5-(1,3-Benzenedioxol-5-yl)-2,4-pentadienoic acid, 9ci; 5-(1,3-Benzodioxol-5-yl)-2,4-pentadienoic acid; 5-(1,3-Benzodioxol-5-yl)penta-2,4-dienoic acid; Piperic acid (8ci); Piperic acid, 8ci; Piperinic acid; Piperonic acid



相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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Plant Reactome(0)

INOH(0)

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COVID-19 Disease Map(0)

PathBank(0)

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11 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • G N Yatoo, Basharat A Bhat, Zubaid-Ul-Khazir, Mohammad Asif, Sajad A Bhat, Farhana Gulzar, Fehmida Rashied, Abdul Haleem Wani, Ishfaq Ahmed, Sajad Majeed Zargar, Mushtaq A Mir, Javid A Banday. Network pharmacology and experimental insights into STAT3 inhibition by novel isoxazole derivatives of piperic acid in triple negative breast cancer. Fitoterapia. 2024 Jun; 175(?):105927. doi: 10.1016/j.fitote.2024.105927. [PMID: 38548028]
  • Tianze Li, Min Lv, Hui Xu. Construction of new oxime esters of cholesterol containing piperic acid-like fragments as insecticidal agents against Aphis citricola Van der Goot (Homoptera: Aphididae) and Plutella xylostella Linnaeus (Lepidoptera: Plutellidae). Bioorganic & medicinal chemistry letters. 2022 04; 62(?):128634. doi: 10.1016/j.bmcl.2022.128634. [PMID: 35202810]
  • Zhehao Jin, Juraithip Wungsintaweekul, Sang-Hoon Kim, Jeong-Han Kim, Yongho Shin, Dae-Kyun Ro, Soo-Un Kim. 4-Coumarate:coenzyme A ligase isoform 3 from Piper nigrum (Pn4CL3) catalyzes the CoA thioester formation of 3,4-methylenedioxycinnamic and piperic acids. The Biochemical journal. 2020 01; 477(1):61-74. doi: 10.1042/bcj20190527. [PMID: 31764941]
  • Ayat S Hammad, Sreenithya Ravindran, Ashraf Khalil, Shankar Munusamy. Structure-activity relationship of piperine and its synthetic amide analogs for therapeutic potential to prevent experimentally induced ER stress in vitro. Cell stress & chaperones. 2017 05; 22(3):417-428. doi: 10.1007/s12192-017-0786-9. [PMID: 28397086]
  • Youli Lu, Narisu Bao, Gereltu Borjihan, Yanling Ma, Miaomiao Hu, Chen Yu, Shuijun Li, Jingying Jia, Ding Yang, Yiping Wang. Contribution of carboxylesterase in hamster to the intestinal first-pass loss and low bioavailability of ethyl piperate, an effective lipid-lowering drug candidate. Drug metabolism and disposition: the biological fate of chemicals. 2011 May; 39(5):796-802. doi: 10.1124/dmd.110.037614. [PMID: 21346005]