Epirubicin (BioDeep_00000405811)
Main id: BioDeep_00000014656
Chemicals and Drugs
代谢物信息卡片
4-Epidoxorubicin
化学式: C27H29NO11 (543.1740524)
中文名称: 表柔比星
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N)O
InChI: InChI=1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17-,22-,27-/m0/s1
描述信息
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01D - Cytotoxic antibiotics and related substances > L01DB - Anthracyclines and related substances
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor
D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059005 - Topoisomerase II Inhibitors
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C259 - Antineoplastic Antibiotic
C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor > C1748 - Topoisomerase Inhibitor
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent
An anthracycline that is the 4-epi-isomer of doxorubicin.
D004791 - Enzyme Inhibitors
Same as: D07901
同义名列表
2 个代谢物同义名
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:47898
- KEGG: C11230
- KEGGdrug: D07901
- PubChem: 41867
- DrugBank: DB00445
- ChEMBL: CHEMBL417
- MeSH: Epirubicin
- CAS: 56420-45-2
- MoNA: FiehnHILIC002685
- MoNA: FiehnHILIC001915
- MoNA: FiehnHILIC001175
- MoNA: FiehnHILIC000334
- MetaboLights: MTBLC47898
- PubChem: 13409
- PDB-CCD: DM6
- NIKKAJI: J81.933F
- RefMet: Epirubicin
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
- 1950 Streptomyces peucetius: 10.1038/NBT0198-69
- 1950 Streptomyces peucetius: 10.1038/NBT0198-69
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ji'an He, Mei Li, Yan Xu, Ning Fan, Chong Tian, Tianye Lv, Wenge Xing, Haipeng Yu. In vitro characteristics of Epirubicin-loaded thermosensitive liquid embolic agent.
Journal of cancer research and therapeutics.
2023 Dec; 19(6):1597-1602. doi:
10.4103/jcrt.jcrt_334_23. [PMID: 38156927] - Solomon Owumi, Uche Arunsi, Moses Otunla, Grace Adebisi, Ahmad Altayyar, Chioma Irozuru. 3-Indolepropionic acid mitigates sub-acute toxicity in the cardiomyocytes of epirubicin-treated female rats.
Naunyn-Schmiedeberg's archives of pharmacology.
2023 Jul; ?(?):. doi:
10.1007/s00210-023-02618-y. [PMID: 37477660] - Shilin Tian, Yue Lu, Haifeng Gao, Zitong Chen, Min Niu, Changjun Wang, Bin Liu. Epirubicin may enhance the inhibition of hepatocellular carcinoma induced by iodine-125 seeds through downregulating WNT pathway.
Asia-Pacific journal of clinical oncology.
2023 Jun; 19(3):355-364. doi:
10.1111/ajco.13873. [PMID: 36464954] - Yu-Jia Wang, Ling Tang, Xu-Hong Lu, Ji-Tao Liu, Yuan-Yuan Wang, Hong-Xia Geng, Xue-Tao Li, Quan An. Efficacy of epi-1 modified epirubicin and curcumin encapsulated liposomes targeting-EpCAM in the inhibition of epithelial ovarian cancer cells.
Journal of liposome research.
2023 Jun; 33(2):197-213. doi:
10.1080/08982104.2022.2153138. [PMID: 36440599] - Solomon E Owumi, Grace Adebisi. Epirubicin Treatment Induces Neurobehavioral, Oxido-Inflammatory and Neurohistology Alterations in Rats: Protective Effect of the Endogenous Metabolite of Tryptophan - 3-Indolepropionic Acid.
Neurochemical research.
2023 Apr; ?(?):. doi:
10.1007/s11064-023-03941-9. [PMID: 37097396] - Gang Yuan, Yanneng Xu, Xiaopeng Bai, Weiming Wang, Xuan Wu, Jianli Chen, Jie Li, Xiaohui Jia, Zeyun Gu, Xun Zhang, Wei Hu, Jianfang Wang, Yong Liu, Xiao-Ming Zhu. Autophagy-Targeted Calcium Phosphate Nanoparticles Enable Transarterial Chemoembolization for Enhanced Cancer Therapy.
ACS applied materials & interfaces.
2023 Feb; ?(?):. doi:
10.1021/acsami.2c18267. [PMID: 36848495] - Hongli Yu, Jianqin Yan, Zhipeng Li, Tingting Song, Fang Ning, Jinshan Tan, Yong Sun. Enhanced photothermal-ferroptosis effects based on RBCm-coated PDA nanoparticles for effective cancer therapy.
Journal of materials chemistry. B.
2023 01; 11(2):415-429. doi:
10.1039/d2tb02329f. [PMID: 36512437] - Xiaofang Li, Xin Guo, Jun Li, Li Yuan, Haixiong Wang. Preventing effect of astragalus polysaccharide on cardiotoxicity induced by chemotherapy of epirubicin: A pilot study.
Medicine.
2022 Aug; 101(32):e30000. doi:
10.1097/md.0000000000030000. [PMID: 35960075] - Wei Ha, Jun-Li Yang, Yan-Ping Shi. Antibacterial metal-phenolic nanosheets as smart carriers for the controlled release of epirubicin hydrochloride.
Nanoscale.
2022 Jul; 14(27):9806-9817. doi:
10.1039/d2nr02066a. [PMID: 35770915] - P Rollin, E Xylinas, C Lanz, F Audenet, S Brunelle, E Compérat, N Houédé, S Larré, A Masson-Lecomte, G Pignot, M Roumiguié, A Méjean, M Rouprêt, Y Neuzillet. [Intravesical adjuvant regimen of epitubicin for intermediate risk NMIBC: Feasability study from CC-AFU vessie].
Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie.
2022 Apr; 32(5):326-331. doi:
10.1016/j.purol.2021.12.008. [PMID: 35151544] - P Leon, F Saint, F Audenet, M Roumiguié, Y Allory, Y Loriot, A Masson-Lecomte, B Pradère, T Seisen, O Traxer, E Xylinas, M Roupret, Y Neuzillet. [Guidelines from the cancer committee of the French Association of Urology (CC-AFU) for adequate intravesical instillations of Mitomycin C, Epirubicin, and BCG for non-muscle invasive bladder cancer].
Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie.
2022 Apr; 32(5):299-311. doi:
10.1016/j.purol.2022.01.004. [PMID: 35151545] - Huaran Zhang, Xuejia Zhang, Yun Huang, Jie Yuan, Xiaoyi Wei, Jianhua Ju. Discovery, Structure Correction, and Biosynthesis of Actinopyrones, Cytotoxic Polyketides from the Deep-Sea Hydrothermal-Vent-Derived Streptomyces sp. SCSIO ZS0520.
Journal of natural products.
2022 03; 85(3):625-633. doi:
10.1021/acs.jnatprod.1c00901. [PMID: 34852194] - Dehua Kong, Wenyu Hong, Miao Yu, Yanxia Li, YaXin Zheng, Xue Ying. Multifunctional Targeting Liposomes of Epirubicin Plus Resveratrol Improved Therapeutic Effect on Brain Gliomas.
International journal of nanomedicine.
2022; 17(?):1087-1110. doi:
10.2147/ijn.s346948. [PMID: 35313461] - Luo Qiong, Jun Yin. Orosomucoid 1 promotes epirubicin resistance in breast cancer by upregulating the expression of matrix metalloproteinases 2 and 9.
Bioengineered.
2021 12; 12(1):8822-8832. doi:
10.1080/21655979.2021.1987067. [PMID: 34654351] - Elizabeth C Smyth, Georgios Vlachogiannis, Somaieh Hedayat, Alice Harbery, Sanna Hulkki-Wilson, Massimiliano Salati, Kyriakos Kouvelakis, Javier Fernandez-Mateos, George D Cresswell, Elisa Fontana, Therese Seidlitz, Clare Peckitt, Jens C Hahne, Andrea Lampis, Ruwaida Begum, David Watkins, Sheela Rao, Naureen Starling, Tom Waddell, Alicia Okines, Tom Crosby, Was Mansoor, Jonathan Wadsley, Gary Middleton, Matteo Fassan, Andrew Wotherspoon, Chiara Braconi, Ian Chau, Igor Vivanco, Andrea Sottoriva, Daniel E Stange, David Cunningham, Nicola Valeri. EGFR amplification and outcome in a randomised phase III trial of chemotherapy alone or chemotherapy plus panitumumab for advanced gastro-oesophageal cancers.
Gut.
2021 09; 70(9):1632-1641. doi:
10.1136/gutjnl-2020-322658. [PMID: 33199443] - Margarita Y Zhelyazkova, Nadya G Hristova-Avakumova, Georgi Tsv Momekov. Antitumor activity of the combination of artemisinin and epirubicin in human leukemia cells.
Folia medica.
2021 Aug; 63(4):488-495. doi:
10.3897/folmed.63.e55938. [PMID: 35851170] - Xue-Tao Li, Ming Jing, Fu-Yi Cai, Xue-Min Yao, Liang Kong, Xiao-Bo Wang. Enhanced antitumour efficiency of R8GD-modified epirubicin plus tetrandrine liposomes in treatment of gastric cancer via inhibiting tumour metastasis.
Journal of liposome research.
2021 Jun; 31(2):145-157. doi:
10.1080/08982104.2020.1748647. [PMID: 32223361] - Julie M Janssen, Kristel Van Calsteren, Thomas P C Dorlo, Michael J Halaska, Robert Fruscio, Petronella Ottevanger, Carolien P Schröder, Ingrid Boere, Petronella O Witteveen, Rebecca C Painter, Ruud Bekkers, Vit Drochytek, Jos H Beijnen, Alwin D R Huitema, Frederic C H Amant. Population Pharmacokinetics of Docetaxel, Paclitaxel, Doxorubicin and Epirubicin in Pregnant Women with Cancer: A Study from the International Network of Cancer, Infertility and Pregnancy (INCIP).
Clinical pharmacokinetics.
2021 06; 60(6):775-784. doi:
10.1007/s40262-020-00961-4. [PMID: 33506375] - Yi-Ting Lin, Xin-Yue Zheng, Yi-Fan Yao, Yu-Ying Zhang, Ting-Ting Huang, Yun-Lan Zhu, Jun Pei, Jin Wang, Ming Chu, Yue-Dan Wang. [Therapeutic Effect of Spleen Low Molecular Weight Extracts on Leukopenia Caused by Epirubicin in Mice and Its Mechanism].
Zhongguo shi yan xue ye xue za zhi.
2021 Jun; 29(3):969-974. doi:
10.19746/j.cnki.issn.1009-2137.2021.03.050. [PMID: 34105502] - Irisvan S Ribeiro, Francisco J G Pontes, Maria J M Carneiro, Nayara A Sousa, Vicente P T Pinto, Fábio O S Ribeiro, Durcilene A Silva, Gisele S Araújo, José D B Marinho Filho, Ana J Araújo, Haroldo C B Paula, Judith P A Feitosa, Regina C M de Paula. Poly(ε-caprolactone) grafted cashew gum nanoparticles as an epirubicin delivery system.
International journal of biological macromolecules.
2021 May; 179(?):314-323. doi:
10.1016/j.ijbiomac.2021.03.011. [PMID: 33675833] - Alessandro De Vita, Chiara Liverani, Roberto Molinaro, Jonathan O Martinez, Kelly A Hartman, Chiara Spadazzi, Giacomo Miserocchi, Francesca Taraballi, Michael Evangelopoulos, Federica Pieri, Alberto Bongiovanni, Laura Mercatali, Ennio Tasciotti, Toni Ibrahim. Lysyl oxidase engineered lipid nanovesicles for the treatment of triple negative breast cancer.
Scientific reports.
2021 03; 11(1):5107. doi:
10.1038/s41598-021-84492-3. [PMID: 33658580] - Balasubramani Gl, Rinky Rajput, Manish Gupta, Pradeep Dahiya, Jitendra K Thakur, Rakesh Bhatnagar, Abhinav Grover. Structure-based drug repurposing to inhibit the DNA gyrase of Mycobacterium tuberculosis.
The Biochemical journal.
2020 11; 477(21):4167-4190. doi:
10.1042/bcj20200462. [PMID: 33030198] - Junjie Li, Keda Yu, Da Pang, Changqin Wang, Jun Jiang, Suisheng Yang, Yunjiang Liu, Peifen Fu, Yuan Sheng, Guojun Zhang, Yali Cao, Qi He, Shude Cui, Xijing Wang, Guosheng Ren, Xinzheng Li, Shiyou Yu, Pengxi Liu, Xiang Qu, Jinhai Tang, Ouchen Wang, Zhimin Fan, Guoqin Jiang, Jin Zhang, Jiandong Wang, Hongwei Zhang, Shui Wang, Jianguo Zhang, Feng Jin, Nanyan Rao, Binlin Ma, Pingqing He, Binghe Xu, Zhigang Zhuang, Jianfeng Wang, Qiang Sun, Xiaofeng Guo, Miao Mo, Zhimin Shao. Adjuvant Capecitabine With Docetaxel and Cyclophosphamide Plus Epirubicin for Triple-Negative Breast Cancer (CBCSG010): An Open-Label, Randomized, Multicenter, Phase III Trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2020 06; 38(16):1774-1784. doi:
10.1200/jco.19.02474. [PMID: 32275467] - Bernhard Tribukait. Early prediction of pathologic response to neoadjuvant treatment of breast cancer: use of a cell-loss metric based on serum thymidine kinase 1 and tumour volume.
BMC cancer.
2020 May; 20(1):440. doi:
10.1186/s12885-020-06925-y. [PMID: 32423477] - Liangliang Bi, Huaxing Zhang, Ruoling Han, Wei Chen, Na Zhao. Application of a combination of echocardiographic techniques in an experimental model of epirubicin-induced cardiotoxicity.
The international journal of cardiovascular imaging.
2020 May; 36(5):841-854. doi:
10.1007/s10554-020-01777-w. [PMID: 32034566] - Shujun Li, Yahai Liang, Yanxia Wu, Zhong Huang, Yanming Lin, Zhixiong Yang, Hualin Chen, Aibing Wu. A comparative study on etoposide combined with lobaplatin or cisplatin in the first-line treatment of extensive-stage small cell lung cancer.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology.
2020 May; 25(3):1490-1496. doi:
NULL. [PMID: 32862595] - Mariann Gyöngyösi, Dominika Lukovic, Katrin Zlabinger, Andreas Spannbauer, Alfred Gugerell, Noemi Pavo, Denise Traxler, Dietmar Pils, Gerald Maurer, Andras Jakab, Martin Riesenhuber, Andreas Pircher, Johannes Winkler, Jutta Bergler-Klein. Liposomal doxorubicin attenuates cardiotoxicity via induction of interferon-related DNA damage resistance.
Cardiovascular research.
2020 04; 116(5):970-982. doi:
10.1093/cvr/cvz192. [PMID: 31346605] - Ming Jing, Xiao-Jie Bi, Xue-Min Yao, Fuyi Cai, Jing-Jing Liu, Min Fu, Liang Kong, Xin-Ze Liu, Lu Zhang, Si-Yu He, Lian-Qun Jia, Xue-Tao Li. Enhanced antitumor efficacy using epirubicin and schisandrin B co-delivery liposomes modified with PFV via inhibiting tumor metastasis.
Drug development and industrial pharmacy.
2020 Apr; 46(4):621-634. doi:
10.1080/03639045.2020.1742145. [PMID: 32162988] - Junhui Sun, Guanhui Zhou, Xiaoxi Xie, Wenjiang Gu, Jing Huang, Dedong Zhu, Wenhao Hu, Qinming Hou, Changsheng Shi, Tiefeng Li, Xin Zhang, Wenbin Ji, Shihong Ying, Zhiyi Peng, Jian Zhou, Zhihai Yu, Jiansong Ji, Haijun Du, Xiaohua Guo, Jian Fang, Jun Han, Huanhai Xu, Zhichao Sun, Wenqiang Yu, Guoliang Shao, Xia Wu, Hongjie Hu, Ling Li, Jiaping Zheng, Jun Luo, Yutang Chen, Guohong Cao, Tingyang Hu. Efficacy and Safety of Drug-Eluting Beads Transarterial Chemoembolization by CalliSpheres® in 275 Hepatocellular Carcinoma Patients: Results From the Chinese CalliSpheres® Transarterial Chemoembolization in Liver Cancer (CTILC) Study.
Oncology research.
2020 Feb; 28(1):75-94. doi:
10.3727/096504019x15662966719585. [PMID: 31558180] - Tetsuya Masada, Toshihiro Tanaka, Hideyuki Nishiofuku, Yasushi Fukuoka, Ryosuke Taiji, Takeshi Sato, Shota Tatsumoto, Kiyoyuki Minamiguchi, Nagaaki Marugami, Kimihiko Kichikawa. Use of a Glass Membrane Pumping Emulsification Device Improves Systemic and Tumor Pharmacokinetics in Rabbit VX2 Liver Tumor in Transarterial Chemoembolization.
Journal of vascular and interventional radiology : JVIR.
2020 Feb; 31(2):347-351. doi:
10.1016/j.jvir.2019.06.015. [PMID: 31542274] - Liang Kong, Fu-Yi Cai, Xue-Min Yao, Ming Jing, Min Fu, Jing-Jing Liu, Si-Yu He, Lu Zhang, Xin-Ze Liu, Rui-Jun Ju, Xue-Tao Li. RPV-modified epirubicin and dioscin co-delivery liposomes suppress non-small cell lung cancer growth by limiting nutrition supply.
Cancer science.
2020 Feb; 111(2):621-636. doi:
10.1111/cas.14256. [PMID: 31777993] - Xiang Li, Qian Zou, Jing Zhang, Peng Zhang, Xiong Zhou, Satya Siva Kishan Yalamarty, Xinli Liang, Yali Liu, Qin Zheng, Jianqing Gao. Self-Assembled Dual-Targeted Epirubicin-Hybrid Polydopamine Nanoparticles for Combined Chemo-Photothermal Therapy of Triple-Negative Breast Cancer.
International journal of nanomedicine.
2020; 15(?):6791-6811. doi:
10.2147/ijn.s260477. [PMID: 32982234] - Natalia Treder, Olga Maliszewska, Ilona Olędzka, Piotr Kowalski, Natalia Miękus, Tomasz Bączek, Ewa Bień, Małgorzata Anna Krawczyk, Elżbieta Adamkiewicz-Drożynska, Alina Plenis. Development and validation of a high-performance liquid chromatographic method with a fluorescence detector for the analysis of epirubicin in human urine and plasma, and its application in drug monitoring.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2020 Jan; 1136(?):121910. doi:
10.1016/j.jchromb.2019.121910. [PMID: 31830661] - Nezhat Jandaghi, Shohreh Jahani, Mohammad Mehdi Foroughi, Maryam Kazemipour, Mehdi Ansari. Cerium-doped flower-shaped ZnO nano-crystallites as a sensing component for simultaneous electrochemical determination of epirubicin and methotrexate.
Mikrochimica acta.
2019 12; 187(1):24. doi:
10.1007/s00604-019-4016-2. [PMID: 31807919] - Ai Ch'i Liew, Kok-Khiang Peh, Boon Seang Tan, Wei Zhao, Balamurugan Tangiisuran. Evaluation of chemotherapy-induced toxicity and health-related quality of life amongst early-stage breast cancer patients receiving Chinese herbal medicine in Malaysia.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer.
2019 Dec; 27(12):4515-4524. doi:
10.1007/s00520-019-04724-1. [PMID: 30911917] - Neng Wang, Bowen Yang, Gulizeba Muhetaer, Shengqi Wang, Yifeng Zheng, Jiahong Lu, Min Li, Fengxue Zhang, Honglin Situ, Yi Lin, Zhiyu Wang. XIAOPI formula promotes breast cancer chemosensitivity via inhibiting CXCL1/HMGB1-mediated autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2019 Dec; 120(?):109519. doi:
10.1016/j.biopha.2019.109519. [PMID: 31629951] - Jing-Jing Liu, Wei Tang, Min Fu, Xiao-Qing Gong, Liang Kong, Xue-Min Yao, Ming Jing, Fu-Yi Cai, Xue-Tao Li, Rui-Jun Ju. Development of R8 modified epirubicin-dihydroartemisinin liposomes for treatment of non-small-cell lung cancer.
Artificial cells, nanomedicine, and biotechnology.
2019 Dec; 47(1):1947-1960. doi:
10.1080/21691401.2019.1615932. [PMID: 31079495] - Qingying Guo, Min Liu, Yanna Zhao, Yushu Wu, Jie Liu, Chang Cai, Yabo Shi, Jun Han. Spectroscopic and cytotoxicity studies on the combined interaction of (-)-epigallocatechin-3-gallate and anthracycline drugs with human serum albumin.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2019 Nov; 222(?):117213. doi:
10.1016/j.saa.2019.117213. [PMID: 31177010] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Klaudia K Brodaczewska, Zofia F Bielecka, Kamila Maliszewska-Olejniczak, Cezary Szczylik, Camillo Porta, Ewa Bartnik, Anna M Czarnecka. Metastatic renal cell carcinoma cells growing in 3D on poly‑D‑lysine or laminin present a stem‑like phenotype and drug resistance.
Oncology reports.
2019 Nov; 42(5):1878-1892. doi:
10.3892/or.2019.7321. [PMID: 31545459] - Wenjiao Jiang, Huijie Guo, Dongyuan Su, Hongjiang Xu, Hongmei Gu, Kun Hao. Ameliorative effect of Magnesium Isoglycyrrhizinate on hepatic encephalopathy by Epirubicin.
International immunopharmacology.
2019 Oct; 75(?):105774. doi:
10.1016/j.intimp.2019.105774. [PMID: 31351363] - Xu Jing, Chao Sun, Huigang Chen, Jing Sun, Ying Zhang, Jing Wu. Protection of paeonol against epirubicin-induced hepatotoxicity: A metabolomic study.
Bioscience trends.
2019 Jul; 13(3):253-260. doi:
10.5582/bst.2019.01105. [PMID: 31231109] - Fengyi Guo, Tian Xia, Yedan Zhang, Xiaotong Ma, Zhongrui Yan, Shaohua Hao, Yali Han, Ruihong Ma, Yuan Zhou, Xue Du. Menstrual blood derived mesenchymal stem cells combined with Bushen Tiaochong recipe improved chemotherapy-induced premature ovarian failure in mice by inhibiting GADD45b expression in the cell cycle pathway.
Reproductive biology and endocrinology : RB&E.
2019 Jul; 17(1):56. doi:
10.1186/s12958-019-0499-2. [PMID: 31311554] - Jingxian Gu, Xing Zhang, Ruixia Cui, Jia Zhang, Zhixin Wang, Yifan Jia, Runchen Miao, Yanyan Dong, Xiaohua Ma, Haining Fan, Haijiu Wang, Li Ren, Yiming Li, Wenquan Niu, Jingyao Zhang, Kai Qu, Chang Liu. Prognostic predictors for patients with hepatocellular carcinoma receiving adjuvant transcatheter arterial chemoembolization.
European journal of gastroenterology & hepatology.
2019 Jul; 31(7):836-844. doi:
10.1097/meg.0000000000001346. [PMID: 30614882] - Amirhossein Bahreyni, Mohammad Ramezani, Mona Alibolandi, Pirooz Hassanzadeh, Khalil Abnous, Seyed Mohammad Taghdisi. High affinity of AS1411 toward copper; its application in a sensitive aptasensor for copper detection.
Analytical biochemistry.
2019 06; 575(?):1-9. doi:
10.1016/j.ab.2019.03.016. [PMID: 30926271] - Laura Martínez-Sogues, Anna Vila, Xavier Roura, Josep Pastor, Rosa Novellas, Alberto Marco, Maria Cuvertoret-Sanz, Jorge Martínez, Laia Solano-Gallego. Hypercalcemia of Malignancy in a Dog Diagnosed With Cholangiocellular Carcinoma.
Topics in companion animal medicine.
2019 Jun; 35(?):1-5. doi:
10.1053/j.tcam.2019.02.001. [PMID: 31122681] - Ean-Jeong Seo, Sabine M Klauck, Thomas Efferth, Alexander Panossian. Adaptogens in chemobrain (Part II): Effect of plant extracts on chemotherapy-induced cytotoxicity in neuroglia cells.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2019 May; 58(?):152743. doi:
10.1016/j.phymed.2018.11.004. [PMID: 30901664] - Bin Huang, Jiabo Zheng, Zhijun Yao, Wenzhe Fan, Shaopeng Qiu, Lingwu Chen, Junxing Chen. Efficacy of intra-arterial chemotherapy combined with intravesical chemotherapy in T1G3 bladder cancer when compared with intravesical chemotherapy alone after bladder-sparing surgery: a retrospective study.
World journal of urology.
2019 May; 37(5):823-829. doi:
10.1007/s00345-018-2437-x. [PMID: 30191393] - Ean-Jeong Seo, Sabine M Klauck, Thomas Efferth, Alexander Panossian. Adaptogens in chemobrain (Part I): Plant extracts attenuate cancer chemotherapy-induced cognitive impairment - Transcriptome-wide microarray profiles of neuroglia cells.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2019 Mar; 55(?):80-91. doi:
10.1016/j.phymed.2018.10.022. [PMID: 30668446] - Amr A Elsawy, Ahmed M El-Assmy, Mahmoud A Bazeed, Bedeir Ali-El-Dein. The value of immediate postoperative intravesical epirubicin instillation as an adjunct to standard adjuvant treatment in intermediate and high-risk non-muscle-invasive bladder cancer: A preliminary results of randomized controlled trial.
Urologic oncology.
2019 03; 37(3):179.e9-179.e18. doi:
10.1016/j.urolonc.2018.10.019. [PMID: 30448030] - Adrian P Wiegmans, Jodi M Saunus, Sunyoung Ham, Richard Lobb, Jamie R Kutasovic, Andrew J Dalley, Mariska Miranda, Caroline Atkinson, Simote T Foliaki, Kaltin Ferguson, Colleen Niland, Cameron N Johnstone, Victoria Lewis, Steven J Collins, Sunil R Lakhani, Fares Al-Ejeh, Andreas Möller. Secreted cellular prion protein binds doxorubicin and correlates with anthracycline resistance in breast cancer.
JCI insight.
2019 02; 5(?):. doi:
10.1172/jci.insight.124092. [PMID: 30830863] - Jixue Wang, Guanyu Wang, Hongli Shan, Xiaoqing Wang, Chunxi Wang, Xiuli Zhuang, Jianxun Ding, Xuesi Chen. Gradiently degraded electrospun polyester scaffolds with cytostatic for urothelial carcinoma therapy.
Biomaterials science.
2019 Feb; 7(3):963-974. doi:
10.1039/c8bm01317a. [PMID: 30569055] - Amar M Eltweri, Anne L Thomas, Wen Y Chung, Bruno Morgan, John Thompson, Ashley R Dennison, David J Bowrey. The Effect of Supplementary Omegaven® on the Clinical Outcome of Patients With Advanced Esophagogastric Adenocarcinoma Receiving Palliative Epirubicin, Oxaliplatin, and Capecitabine Chemotherapy: A Phase II clinical trial.
Anticancer research.
2019 Feb; 39(2):853-861. doi:
10.21873/anticanres.13185. [PMID: 30711967] - Lian Li, Jiyuan Yang, Sirima Soodvilai, Jiawei Wang, Praneet Opanasopit, Jindřich Kopeček. Drug-free albumin-triggered sensitization of cancer cells to anticancer drugs.
Journal of controlled release : official journal of the Controlled Release Society.
2019 01; 293(?):84-93. doi:
10.1016/j.jconrel.2018.11.015. [PMID: 30465822] - Limei Wang, Jin Pei, Zhongcheng Cong, Yifang Zou, Tianmeng Sun, Fionán Davitt, Adrià Garcia-Gil, Justin D Holmes, Caitriona M O'Driscoll, Kamil Rahme, Jianfeng Guo. Development of anisamide-targeted PEGylated gold nanorods to deliver epirubicin for chemo-photothermal therapy in tumor-bearing mice.
International journal of nanomedicine.
2019; 14(?):1817-1833. doi:
10.2147/ijn.s192520. [PMID: 30880982] - Sanjeev Kumar Sagwal, Gabriella Pasqual-Melo, Yana Bodnar, Rajesh Kumar Gandhirajan, Sander Bekeschus. Combination of chemotherapy and physical plasma elicits melanoma cell death via upregulation of SLC22A16.
Cell death & disease.
2018 12; 9(12):1179. doi:
10.1038/s41419-018-1221-6. [PMID: 30518936] - Pierantonio Menna, Emanuela Salvatorelli, Grazia Armento, Ombretta Annibali, Carlo Greco, Francesco Marchesi, Vito Calabrese, Giorgio Reggiardo, Giorgio Minotti. The Endogenous Lusitropic and Chronotropic Agent, B-Type Natriuretic Peptide, Limits Cardiac Troponin Release in Cancer Patients with an Early Impairment of Myocardial Relaxation Induced by Anthracyclines.
The Journal of pharmacology and experimental therapeutics.
2018 12; 367(3):518-527. doi:
10.1124/jpet.118.253104. [PMID: 30275150] - Prarthana Gopinath, Sridevi Veluswami, Rajkumar Thangarajan, Gopal Gopisetty. RP-HPLC-UV Method for Estimation of Fluorouracil-Epirubicin-Cyclophosphamide and Their Metabolite Mixtures in Human Plasma (Matrix).
Journal of chromatographic science.
2018 Jul; 56(6):488-497. doi:
10.1093/chromsci/bmy020. [PMID: 29608650] - Xiaoyun Song, Xiqiu Zhou, Yuenong Qin, Jianfeng Yang, Yu Wang, Zhenping Sun, Kui Yu, Shuai Zhang, Sheng Liu. Emodin inhibits epithelial‑mesenchymal transition and metastasis of triple negative breast cancer via antagonism of CC‑chemokine ligand 5 secreted from adipocytes.
International journal of molecular medicine.
2018 Jul; 42(1):579-588. doi:
10.3892/ijmm.2018.3638. [PMID: 29693154] - Ting Zhang, Songlei Zhou, Ling Hu, Bo Peng, Yang Liu, Xiang Luo, Xinrong Liu, Yanzhi Song, Yihui Deng. Polysialic acid-polyethylene glycol conjugate-modified liposomes as a targeted drug delivery system for epirubicin to enhance anticancer efficiency.
Drug delivery and translational research.
2018 06; 8(3):602-616. doi:
10.1007/s13346-018-0496-6. [PMID: 29536348] - Fangfang Shi, Miao Li, Jing Wang, Di Wu, Meng Pan, Mei Guo, Jun Dou. Induction of multiple myeloma cancer stem cell apoptosis using conjugated anti-ABCG2 antibody with epirubicin-loaded microbubbles.
Stem cell research & therapy.
2018 05; 9(1):144. doi:
10.1186/s13287-018-0885-2. [PMID: 29784015] - Jing Chen, Yue Zhang, Huihua Cai, Yu Yang, Yun Fei Duan. Comparison of the effects of postoperative prophylactic transcatheter arterial chemoembolization (TACE) and transhepatic arterial infusion (TAI) after hepatectomy for primary liver cancer.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology.
2018 May; 23(3):629-634. doi:
NULL. [PMID: 30003729] - Turkan Ozturk Topcu, Feyyaz Ozdemir, Halil Kavgaci, Meral Gunaldi, Hakan Kocoglu, Goksen Inanc Imamoglu, Ahmet Mentese, Serap Ozer Yaman, Asim Orem, Fazil Aydin. The clinical importance of serum urokinase plasminogen activator receptor and carbonic anhydrase IX levels and the effect of anthracycline-based adjuvant chemotherapy on these biomarkers in breast cancer.
Journal of cancer research and therapeutics.
2018 Apr; 14(3):608-613. doi:
10.4103/0973-1482.174547. [PMID: 29893327] - Michael Stahl, Annett Maderer, Florian Lordick, Andre L Mihaljevic, Stefan Kanzler, Thomas Hoehler, Peter Thuss-Patience, Stefan Mönig, Volker Kunzmann, Sebastian Schroll, Andreas Sandermann, Andrea Tannapfel, Hans-Joachim Meyer, Christoph Schuhmacher, Hansjochen Wilke, Markus Moehler. Perioperative chemotherapy with or without epidermal growth factor receptor blockade in unselected patients with locally advanced oesophagogastric adenocarcinoma: Randomized phase II study with advanced biomarker program of the German Cancer Society (AIO/CAO STO-0801).
European journal of cancer (Oxford, England : 1990).
2018 04; 93(?):119-126. doi:
10.1016/j.ejca.2018.01.079. [PMID: 29501977] - Miao Yu, Shangcong Han, Zhongai Kou, Jialing Dai, Jiao Liu, Chen Wei, Yitong Li, Lutao Jiang, Yong Sun. Lipid nanoparticle-based co-delivery of epirubicin and BCL-2 siRNA for enhanced intracellular drug release and reversing multidrug resistance.
Artificial cells, nanomedicine, and biotechnology.
2018 Mar; 46(2):323-332. doi:
10.1080/21691401.2017.1307215. [PMID: 28393563] - Sachi Morita, Toyone Kikumori, Nobuyuki Tsunoda, Takahiro Inaishi, Yayoi Adachi, Akiko Ota, Masahiro Shibata, Ayumu Matsuoka, Kenichi Nakanishi, Dai Takeuchi, Takefumi Mizutani, Tomoya Shimokata, Hironori Hayashi, Osamu Maeda, Yuichi Ando. Feasibility of dose-dense epirubicin and cyclophosphamide with subcutaneous pegfilgrastim 3.6 mg support: a single-center prospective study in Japan.
International journal of clinical oncology.
2018 Feb; 23(1):195-200. doi:
10.1007/s10147-017-1177-z. [PMID: 28791509] - Xiantao Qin, Fangyuan Chang, Zhenfeng Wang, Wenying Jiang. Correlation of circulating pro-angiogenic miRNAs with cardiotoxicity induced by epirubicin/cyclophosphamide followed by docetaxel in patients with breast cancer.
Cancer biomarkers : section A of Disease markers.
2018; 23(4):473-484. doi:
10.3233/cbm-181301. [PMID: 30452398] - Ge Ma, Huaxing Huang, Minghui Li, Li Li, Peng Kong, Yichao Zhu, Tiansong Xia, Shui Wang. Plasma CCL5 promotes EMT-medicated epirubicin-resistance in locally advanced breast cancer.
Cancer biomarkers : section A of Disease markers.
2018; 22(3):405-415. doi:
10.3233/cbm-170986. [PMID: 29758926] - Yoshihiro Goda, Manabu Morimoto, Kuniyasu Irie, Satoshi Kobayashi, Makoto Ueno, Satoshi Moriya, Shun Tezuka, Shinichi Ohkawa, Soichiro Morinaga, Kazushi Numata, Katsuaki Tanaka, Shin Maeda. Switch to miriplatin for multinodular hepatocellular carcinoma unresponsive to transarterial chemoembolization with epirubicin: a prospective study.
Japanese journal of clinical oncology.
2017 Dec; 47(12):1151-1156. doi:
10.1093/jjco/hyx131. [PMID: 28977459] - Mingzi Zhang, Zhongkai Tian, Yehong Sun. Successful treatment of ovarian cancer with apatinib combined with chemotherapy: A case report.
Medicine.
2017 Nov; 96(45):e8570. doi:
10.1097/md.0000000000008570. [PMID: 29137078] - Yuxiao Yao, Shaoyang Sun, Fei Fei, Jingjing Wang, Youhua Wang, Ranran Zhang, Jing Wu, Lian Liu, Xiuyun Liu, Zhaomeng Cui, Qiang Li, Min Yu, Yongjun Dang, Xu Wang. Screening in larval zebrafish reveals tissue-specific distribution of fifteen fluorescent compounds.
Disease models & mechanisms.
2017 09; 10(9):1155-1164. doi:
10.1242/dmm.028811. [PMID: 28754836] - Xiao-Dong Luan, Kai-Hua Zhao, Hong Hou, Yan-Hong Gai, Qi-Tang Wang, Qiang Mu, Yue Wan. Changes in ischemia-modified albumin in myocardial toxicity induced by anthracycline and docetaxel chemotherapy.
Medicine.
2017 Aug; 96(32):e7681. doi:
10.1097/md.0000000000007681. [PMID: 28796051] - Ting Li, Jin Wang, Pengfei Liu, Jiadong Chi, Han Yan, Lei Lei, Zexing Li, Bing Yang, Xi Wang. Insulin-like growth factor 2 axis supports the serum-independent growth of malignant rhabdoid tumor and is activated by microenvironment stress.
Oncotarget.
2017 Jul; 8(29):47269-47283. doi:
10.18632/oncotarget.17617. [PMID: 28521298] - Na Ling, Xiaojun Zhou, Yubin Ji, Wenlan Li, Chenfeng Ji, Zheng Qi. Immuno-modulatory and cellular antioxidant activities of κ-selenocarrageenan in combination with Epirubicin in H22 hepatoma-bearing mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2017 Jul; 91(?):132-137. doi:
10.1016/j.biopha.2017.04.064. [PMID: 28448867] - A M Eltweri, A L Thomas, H L Fisk, A Arshad, P C Calder, A R Dennison, D J Bowrey. Plasma and erythrocyte uptake of omega-3 fatty acids from an intravenous fish oil based lipid emulsion in patients with advanced oesophagogastric cancer.
Clinical nutrition (Edinburgh, Scotland).
2017 06; 36(3):768-774. doi:
10.1016/j.clnu.2016.06.001. [PMID: 27342748] - Yilong Zhang, Mita Kuchimanchi, Min Zhu, Sameer Doshi, Tien Hoang, Sreeneeranj Kasichayanula. Assessment of pharmacokinetic interaction between rilotumumab and epirubicin, cisplatin and capecitabine (ECX) in a Phase 3 study in gastric cancer.
British journal of clinical pharmacology.
2017 05; 83(5):1048-1055. doi:
10.1111/bcp.13179. [PMID: 27966237] - G Chang, L L Xie, W Y Li, F F Xia, P C Huang, Q R Liu, C D Zhang, T J Zhang, H F Li. Application of oxaliplatin in combination with epirubicin in transcatheter arterial chemoembolization in the treatment of primary liver carcinoma.
Journal of biological regulators and homeostatic agents.
2017 Apr; 31(2):459-464. doi:
NULL. [PMID: 28685553] - M L Wumkes, A M T van der Velden, E de Bruin, A Meerveld-Eggink, M P G Koopmans, G F Rimmelzwaan, G T Rijkers, D H Biesma. Microarray profile of the humoral immune response to influenza vaccination in breast cancer patients treated with chemotherapy.
Vaccine.
2017 03; 35(9):1299-1305. doi:
10.1016/j.vaccine.2017.01.039. [PMID: 28169075] - Diane D Lu, Stephen A Boorjian, Jay D Raman. Intravesical chemotherapy use after radical nephroureterectomy: A national survey of urologic oncologists.
Urologic oncology.
2017 03; 35(3):113.e1-113.e7. doi:
10.1016/j.urolonc.2016.10.016. [PMID: 27884539] - Huixia Xiong, Quanping Diao, Rui Jin, Daqian Song, Xinghua Wang, Ying Sun. Synthesis and application of thiol-functionalized magnetic nanoparticles for studying interactions of epirubicin hydrochloride with bovine serum albumin by fluorescence spectrometry.
Luminescence : the journal of biological and chemical luminescence.
2017 Mar; 32(2):142-148. doi:
10.1002/bio.3158. [PMID: 27193868] - Gang Chen, Ding Zhang, Yacao Ying, Zhifeng Wang, Wei Tao, Hao Zhu, Jingfeng Zhang, Zhiyi Peng. [Clinical investigation on transarterial chemoembolization with indigenous drug-eluting beads in treatment of unresectable hepatocellular carcinoma].
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences.
2017 01; 46(1):44-51. doi:
10.3785/j.issn.1008-9292.2017.02.07. [PMID: 28436630] - Jing Wu, Linlin Xu, Chao Sun, Bin Zhang, Juan Li, Jing Sun, Ying Zhang, Deqing Sun. Paeonol alleviates epirubicin-induced renal injury in mice by regulating Nrf2 and NF-κB pathways.
European journal of pharmacology.
2017 Jan; 795(?):84-93. doi:
10.1016/j.ejphar.2016.12.005. [PMID: 27940053] - Feng-Wei Lin, Pin-Yuan Chen, Kuo-Chen Wei, Chiung-Yin Huang, Chih-Kuang Wang, Hung-Wei Yang. Rapid In Situ MRI Traceable Gel-forming Dual-drug Delivery for Synergistic Therapy of Brain Tumor.
Theranostics.
2017; 7(9):2524-2536. doi:
10.7150/thno.19856. [PMID: 28744332] - Xiao-Li Song, Rui-Jun Ju, Yao Xiao, Xin Wang, Shuang Liu, Min Fu, Jing-Jing Liu, Li-Yan Gu, Xue-Tao Li, Lan Cheng. Application of multifunctional targeting epirubicin liposomes in the treatment of non-small-cell lung cancer.
International journal of nanomedicine.
2017; 12(?):7433-7451. doi:
10.2147/ijn.s141787. [PMID: 29066893] - Yuanqan Huang, Zhongzhi Jia, Jianfei Tu, Tao Shen, Feng Tian, Guomin Jiang. Supplemental conventional transarterial embolization/chemoembolization therapy via extrahepatic arteries for hepatocellular carcinoma.
Journal of cancer research and therapeutics.
2017; 13(4):720-724. doi:
10.4103/jcrt.jcrt_993_16. [PMID: 28901321] - Fang Yang, Qiao Lei, Lu Li, Jian Chang He, Jiajia Zeng, Chunxiang Luo, Sai-Ching Jim Yeung, Runxiang Yang. Delivery of epirubicin via slow infusion as a strategy to mitigate chemotherapy-induced cardiotoxicity.
PloS one.
2017; 12(11):e0188025. doi:
10.1371/journal.pone.0188025. [PMID: 29131861] - Clara M W S Abreu, Haroldo C B Paula, Vitor Seabra, Judith P A Feitosa, Bruno Sarmento, Regina C M de Paula. Synthesis and characterization of non-toxic and thermo-sensitive poly(N-isopropylacrylamide)-grafted cashew gum nanoparticles as a potential epirubicin delivery matrix.
Carbohydrate polymers.
2016 Dec; 154(?):77-85. doi:
10.1016/j.carbpol.2016.08.031. [PMID: 27577899] - Alexandre A Barros, Shane Browne, Carlos Oliveira, Estevão Lima, Ana Rita C Duarte, Kevin E Healy, Rui L Reis. Drug-eluting biodegradable ureteral stent: New approach for urothelial tumors of upper urinary tract cancer.
International journal of pharmaceutics.
2016 Nov; 513(1-2):227-237. doi:
10.1016/j.ijpharm.2016.08.061. [PMID: 27590593] - Hui Li, Yiqing Mao, Qun Zhang, Qing Han, Zhenming Man, Jingyu Zhang, Xi Wang, Ruobi Hu, Xuehui Zhang, David M Irwin, Gang Niu, Huanran Tan. Xinmailong mitigated epirubicin-induced cardiotoxicity via inhibiting autophagy.
Journal of ethnopharmacology.
2016 Nov; 192(?):459-470. doi:
10.1016/j.jep.2016.08.031. [PMID: 27586823] - J Furlanetto, W Eiermann, F Marmé, T Reimer, M Reinisch, S Schmatloch, E Stickeler, C Thomssen, M Untch, C Denkert, G von Minckwitz, B Lederer, V Nekljudova, K Weber, S Loibl, V Möbus. Higher rate of severe toxicities in obese patients receiving dose-dense (dd) chemotherapy according to unadjusted body surface area: results of the prospectively randomized GAIN study.
Annals of oncology : official journal of the European Society for Medical Oncology.
2016 11; 27(11):2053-2059. doi:
10.1093/annonc/mdw315. [PMID: 27502721] - Mohammad Tariq, Md Aftab Alam, Anu T Singh, Amulya K Panda, Sushama Talegaonkar. Improved oral efficacy of epirubicin through polymeric nanoparticles: pharmacodynamic and toxicological investigations.
Drug delivery.
2016 Oct; 23(8):2990-2997. doi:
10.3109/10717544.2015.1136713. [PMID: 26800371] - Libin Zhang, Rui Zhang, Jiyuan Yang, Jiawei Wang, Jindřich Kopeček. Indium-based and iodine-based labeling of HPMA copolymer-epirubicin conjugates: Impact of structure on the in vivo fate.
Journal of controlled release : official journal of the Controlled Release Society.
2016 08; 235(?):306-318. doi:
10.1016/j.jconrel.2016.06.004. [PMID: 27266365] - Hou-Pan Song, Ru-Liu Li, Yi-Yu Wang, Xiao-Hua Tu, Jiao Deng, Wei-Wen Chen. [Effects of Methanol Extracts from Atractylodes macrocephalae Rhizoma on Small Intestinal Epi- thelial Cell Proliferation and Migration, and Expression of Phospholipase C-γl].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2016 07; 36(7):861-866. doi:
. [PMID: 30634216] - Eman I El-Kimary, Amira F El-Yazbi. An eco-friendly stability-indicating spectrofluorimetric method for the determination of two anticancer stereoisomer drugs in their pharmaceutical preparations following micellar enhancement: Application to kinetic degradation studies.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2016 Jun; 163(?):145-53. doi:
10.1016/j.saa.2016.03.034. [PMID: 27045788] - Chiaming Fan, Kristen R Georgiou, Ross A McKinnon, Dorothy M K Keefe, Peter R C Howe, Cory J Xian. Combination chemotherapy with cyclophosphamide, epirubicin and 5-fluorouracil causes trabecular bone loss, bone marrow cell depletion and marrow adiposity in female rats.
Journal of bone and mineral metabolism.
2016 May; 34(3):277-90. doi:
10.1007/s00774-015-0679-x. [PMID: 26056019] - Lijun Luo, Chunyang Zhou, Ying Hui, Katsuhisa Kurogi, Yoichi Sakakibara, Masahito Suiko, Ming-Cheh Liu. Human cytosolic sulfotransferase SULT1C4 mediates the sulfation of doxorubicin and epirubicin.
Drug metabolism and pharmacokinetics.
2016 Apr; 31(2):163-6. doi:
10.1016/j.dmpk.2016.01.003. [PMID: 26948952] - Li-han Zhang, Ai-jun Yang, Min Wang, Wei Liu, Chen-yu Wang, Xiao-feng Xie, Xu Chen, Jing-fei Dong, Min Li. Enhanced autophagy reveals vulnerability of P-gp mediated epirubicin resistance in triple negative breast cancer cells.
Apoptosis : an international journal on programmed cell death.
2016 Apr; 21(4):473-88. doi:
10.1007/s10495-016-1214-9. [PMID: 26767845] - Jing Wu, Xia Xue, Bin Zhang, Wen Jiang, Hongmei Cao, Rongmei Wang, Deqing Sun, Ruichen Guo. The protective effects of paeonol against epirubicin-induced hepatotoxicity in 4T1-tumor bearing mice via inhibition of the PI3K/Akt/NF-kB pathway.
Chemico-biological interactions.
2016 Jan; 244(?):1-8. doi:
10.1016/j.cbi.2015.11.025. [PMID: 26646421] - Monika Sharma, Jo Tuaine, Blair McLaren, Debra L Waters, Katherine Black, Lynnette M Jones, Sally P A McCormick. Chemotherapy Agents Alter Plasma Lipids in Breast Cancer Patients and Show Differential Effects on Lipid Metabolism Genes in Liver Cells.
PloS one.
2016; 11(1):e0148049. doi:
10.1371/journal.pone.0148049. [PMID: 26807857]