BUTYLPARABEN (BioDeep_00000398401)

   

Industrial Pollutants natural product


代谢物信息卡片


BUTYLPARABEN

化学式: C11H14O3 (194.0943)
中文名称: 对羟基苯甲酸正丁酯, 对羟基苯甲酸丁酯, 丁基阿拉伯
谱图信息: 最多检出来源 Viridiplantae(general) 100%

分子结构信息

SMILES: CCCCOC(=O)C1=CC=C(C=C1)O
InChI: InChI=1S/C11H14O3/c1-2-3-8-14-11(13)9-4-6-10(12)7-5-9/h4-7,12H,2-3,8H2,1H3

描述信息

D010592 - Pharmaceutic Aids > D011310 - Preservatives, Pharmaceutical > D010226 - Parabens
CONFIDENCE standard compound; INTERNAL_ID 839; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4733; ORIGINAL_PRECURSOR_SCAN_NO 4731
CONFIDENCE standard compound; INTERNAL_ID 839; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4751; ORIGINAL_PRECURSOR_SCAN_NO 4749
CONFIDENCE standard compound; INTERNAL_ID 839; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4709; ORIGINAL_PRECURSOR_SCAN_NO 4706
CONFIDENCE standard compound; INTERNAL_ID 839; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4734; ORIGINAL_PRECURSOR_SCAN_NO 4732
CONFIDENCE standard compound; INTERNAL_ID 839; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4776; ORIGINAL_PRECURSOR_SCAN_NO 4775
CONFIDENCE standard compound; INTERNAL_ID 839; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4768; ORIGINAL_PRECURSOR_SCAN_NO 4767
CONFIDENCE standard compound; INTERNAL_ID 2368
CONFIDENCE standard compound; INTERNAL_ID 4234
CONFIDENCE standard compound; INTERNAL_ID 8639
CONFIDENCE standard compound; INTERNAL_ID 4158

同义名列表

3 个代谢物同义名

BUTYLPARABEN; BuP; Butylparaben



数据库引用编号

40 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

9 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Lirong Huang, Jiaxin Xu, Kun Jia, Yulin Wu, Wei Yuan, Zhipeng Liao, Bo Cheng, Qiang Luo, Guiyou Tian, Huiqiang Lu. Butylparaben induced zebrafish (Danio rerio) kidney injury by down-regulating the PI3K-AKT pathway. Journal of hazardous materials. 2024 May; 470(?):134129. doi: 10.1016/j.jhazmat.2024.134129. [PMID: 38565019]
  • Mahima Singh, Ajay Guru, Raman Pachaiappan, Bader O Almutairi, Selvaraj Arokiyaraj, Muthukaruppan Gopi, Jesu Arockiaraj. Impact of butylparaben on β-cell damage and insulin/PEPCK expression in zebrafish larvae: Protective effects of morin. Journal of biochemical and molecular toxicology. 2024 Jan; 38(1):e23520. doi: 10.1002/jbt.23520. [PMID: 37632306]
  • Fátima C Martins, M M Oliveira, Isabel Gaivão, Romeu A Videira, Francisco Peixoto. The administration of methyl and butyl parabens interferes with the enzymatic antioxidant system and induces genotoxicity in rat testis: possible relation to male infertility. Drug and chemical toxicology. 2023 Feb; ?(?):1-8. doi: 10.1080/01480545.2023.2176512. [PMID: 36756703]
  • Christy Lite, Ajay Guru, Melita Juliet, Jesu Arockiaraj. Embryonic exposure to butylparaben and propylparaben induced developmental toxicity and triggered anxiety-like neurobehavioral response associated with oxidative stress and apoptosis in the head of zebrafish larvae. Environmental toxicology. 2022 Aug; 37(8):1988-2004. doi: 10.1002/tox.23545. [PMID: 35470536]
  • Frederik Damsgaard Højsager, Henriette Boye Kyhl, Hanne Frederiksen, Anders Juul, Anna-Maria Andersson, Marianne Skovsager Andersen, Anders Grøntved, Tina Kold Jensen. Prenatal Exposure to Butyl Paraben Is Associated With Fat Percentage in 7-Year-Old Boys. The Journal of clinical endocrinology and metabolism. 2021 06; 106(7):e2633-e2638. doi: 10.1210/clinem/dgab167. [PMID: 33720358]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Chaman Ara, Asmatullah, Naila Butt, Shaukat Ali, Farrah Batool, Hafiz Abdullah Shakir, Aqsa Arshad. Abnormal steroidogenesis, oxidative stress, and reprotoxicity following prepubertal exposure to butylparaben in mice and protective effect of Curcuma longa. Environmental science and pollution research international. 2021 Feb; 28(5):6111-6121. doi: 10.1007/s11356-020-10819-8. [PMID: 32986191]
  • Yaghoub Hajizadeh, Ghasem Kiani Feizabadi, Awat Feizi. Dietary Habits and Personal Care Product Use as Predictors of Urinary Concentrations of Parabens in Iranian Adolescents. Environmental toxicology and chemistry. 2020 12; 39(12):2378-2388. doi: 10.1002/etc.4861. [PMID: 32845562]
  • Julie Boberg, Hanna K L Johansson, Marta Axelstad, Gustav P M Olsen, Mathias Johansen, Stine A Holmboe, Anna-Maria Andersson, Terje Svingen. Using assessment criteria for pesticides to evaluate the endocrine disrupting potential of non-pesticide chemicals: Case butylparaben. Environment international. 2020 11; 144(?):105996. doi: 10.1016/j.envint.2020.105996. [PMID: 32771829]
  • Pobi Gogoi, Jogen Ch Kalita. Effects of butylparaben exposure on thyroid peroxidase (TPO) and type 1 iodothyronine deiodinase (D1) in female Wistar rats. Toxicology. 2020 10; 443(?):152562. doi: 10.1016/j.tox.2020.152562. [PMID: 32798586]
  • Ghasem Kiani Feizabadi, Yaghoub Hajizadeh, Awat Feizi, Karim Ebrahimpour. Urinary Concentrations of Parabens in a Population of Iranian Adolescent and Their Association with Sociodemographic Indicators. Archives of environmental contamination and toxicology. 2020 Aug; 79(2):195-207. doi: 10.1007/s00244-020-00746-7. [PMID: 32572517]
  • Na-Youn Park, Yoon Hee Cho, Kyungho Choi, Eun-Hee Lee, Yang Jee Kim, Jung Hoan Kim, Younglim Kho. Parabens in breast milk and possible sources of exposure among lactating women in Korea. Environmental pollution (Barking, Essex : 1987). 2019 Dec; 255(Pt 2):113142. doi: 10.1016/j.envpol.2019.113142. [PMID: 31563777]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Zizhen Zhang, Hao Chen, Ziyang Chen, Peng Ding, Yingchen Ju, Qiong Gu, Jun Xu, Huihao Zhou. Identify liver X receptor β modulator building blocks by developing a fluorescence polarization-based competition assay. European journal of medicinal chemistry. 2019 Sep; 178(?):458-467. doi: 10.1016/j.ejmech.2019.06.011. [PMID: 31202993]
  • Elga Schreiber, Tània Garcia, Raju Prasad Sharma, Margarita Torrente, José Luis Domingo, Mercedes Gómez. Oxidative stress in testes of rats exposed to n-butylparaben. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2019 Sep; 131(?):110573. doi: 10.1016/j.fct.2019.110573. [PMID: 31195070]
  • Sungjin Ahn, Seungchan An, Moonyoung Lee, Eunyoung Lee, Jeong Joo Pyo, Jeong Hyeon Kim, Min Won Ki, Sun Hee Jin, Jaehyoun Ha, Minsoo Noh. A long-wave UVA filter avobenzone induces obesogenic phenotypes in normal human epidermal keratinocytes and mesenchymal stem cells. Archives of toxicology. 2019 07; 93(7):1903-1915. doi: 10.1007/s00204-019-02462-1. [PMID: 31016361]
  • Daniele C Silva, Lenard Serrano, Thiessa M A Oliveira, Adrislaine S Mansano, Eduardo A Almeida, Eny M Vieira. Effects of parabens on antioxidant system and oxidative damages in Nile tilapia (Oreochromis niloticus). Ecotoxicology and environmental safety. 2018 Oct; 162(?):85-91. doi: 10.1016/j.ecoenv.2018.06.076. [PMID: 29990743]
  • Thomas L Gonzalez, Rebecca K Moos, Christina L Gersch, Michael D Johnson, Rudy J Richardson, Holger M Koch, James M Rae. Metabolites of n-Butylparaben and iso-Butylparaben Exhibit Estrogenic Properties in MCF-7 and T47D Human Breast Cancer Cell Lines. Toxicological sciences : an official journal of the Society of Toxicology. 2018 07; 164(1):50-59. doi: 10.1093/toxsci/kfy063. [PMID: 29945225]
  • Yan Du, Zhibin Wang, Libo Wang, Mingjie Gao, Liqian Wang, Chunli Gan, Chunjuan Yang. Simultaneous Determination of Seven Phenolic Acids in Rat Plasma Using UHPLC-ESI-MS/MS after Oral Administration of Echinacea purpurea Extract. Molecules (Basel, Switzerland). 2017 Sep; 22(9):. doi: 10.3390/molecules22091494. [PMID: 28880243]
  • Tyler Pollock, Rachel E Weaver, Ramtin Ghasemi, Denys deCatanzaro. Butyl paraben and propyl paraben modulate bisphenol A and estradiol concentrations in female and male mice. Toxicology and applied pharmacology. 2017 06; 325(?):18-24. doi: 10.1016/j.taap.2017.04.001. [PMID: 28390971]
  • Rebecca K Moos, Jürgen Angerer, Georg Dierkes, Thomas Brüning, Holger M Koch. Metabolism and elimination of methyl, iso- and n-butyl paraben in human urine after single oral dosage. Archives of toxicology. 2016 Nov; 90(11):2699-2709. doi: 10.1007/s00204-015-1636-0. [PMID: 26608183]
  • Pan Hu, Rebekah C Kennedy, Xin Chen, Jia Zhang, Chwan-Li Shen, Jiangang Chen, Ling Zhao. Differential effects on adiposity and serum marker of bone formation by post-weaning exposure to methylparaben and butylparaben. Environmental science and pollution research international. 2016 Nov; 23(21):21957-21968. doi: 10.1007/s11356-016-7452-0. [PMID: 27535158]
  • I Jiménez-Díaz, F Artacho-Cordón, F Vela-Soria, H Belhassen, J P Arrebola, M F Fernández, R Ghali, A Hedhili, N Olea. Urinary levels of bisphenol A, benzophenones and parabens in Tunisian women: A pilot study. The Science of the total environment. 2016 08; 562(?):81-88. doi: 10.1016/j.scitotenv.2016.03.203. [PMID: 27096629]
  • Chun-Juan Yang, Zhi-Bin Wang, Ying-Ying Mi, Ming-Jie Gao, Jin-Nan Lv, Yong-Hai Meng, Bing-You Yang, Hai-Xue Kuang. UHPLC-MS/MS Determination, Pharmacokinetic, and Bioavailability Study of Taxifolin in Rat Plasma after Oral Administration of its Nanodispersion. Molecules (Basel, Switzerland). 2016 Apr; 21(4):494. doi: 10.3390/molecules21040494. [PMID: 27089318]
  • Marina T Varela, Roberto Z Dias, Ligia F Martins, Daiane D Ferreira, Andre G Tempone, Anderson K Ueno, João Henrique G Lago, João Paulo S Fernandes. Gibbilimbol analogues as antiparasitic agents--Synthesis and biological activity against Trypanosoma cruzi and Leishmania (L.) infantum. Bioorganic & medicinal chemistry letters. 2016 Feb; 26(4):1180-3. doi: 10.1016/j.bmcl.2016.01.040. [PMID: 26821820]
  • Priscilla Rocío-Bautista, Carla Martínez-Benito, Verónica Pino, Jorge Pasán, Juan H Ayala, Catalina Ruiz-Pérez, Ana M Afonso. The metal-organic framework HKUST-1 as efficient sorbent in a vortex-assisted dispersive micro solid-phase extraction of parabens from environmental waters, cosmetic creams, and human urine. Talanta. 2015 Jul; 139(?):13-20. doi: 10.1016/j.talanta.2015.02.032. [PMID: 25882402]
  • Jerry L Campbell, Miyoung Yoon, Harvey J Clewell. A case study on quantitative in vitro to in vivo extrapolation for environmental esters: Methyl-, propyl- and butylparaben. Toxicology. 2015 Jun; 332(?):67-76. doi: 10.1016/j.tox.2015.03.010. [PMID: 25839974]
  • Deborah J Watkins, Kelly K Ferguson, Liza V Anzalota Del Toro, Akram N Alshawabkeh, José F Cordero, John D Meeker. Associations between urinary phenol and paraben concentrations and markers of oxidative stress and inflammation among pregnant women in Puerto Rico. International journal of hygiene and environmental health. 2015 Mar; 218(2):212-9. doi: 10.1016/j.ijheh.2014.11.001. [PMID: 25435060]
  • Ivana Klopčič, Katra Kolšek, Marija Sollner Dolenc. Glucocorticoid-like activity of propylparaben, butylparaben, diethylhexyl phthalate and tetramethrin mixtures studied in the MDA-kb2 cell line. Toxicology letters. 2015 Jan; 232(2):376-83. doi: 10.1016/j.toxlet.2014.11.019. [PMID: 25448277]
  • Linyuan Zhang, Li Dong, Sijin Ding, Peihuan Qiao, Chong Wang, Ming Zhang, Lixia Zhang, Qingcheng Du, Yimin Li, Ning Tang, Bing Chang. Effects of n-butylparaben on steroidogenesis and spermatogenesis through changed E₂ levels in male rat offspring. Environmental toxicology and pharmacology. 2014 Mar; 37(2):705-17. doi: 10.1016/j.etap.2014.01.016. [PMID: 24607685]
  • Kristen W Smith, Irene Souter, Irene Dimitriadis, Shelley Ehrlich, Paige L Williams, Antonia M Calafat, Russ Hauser. Urinary paraben concentrations and ovarian aging among women from a fertility center. Environmental health perspectives. 2013 Nov; 121(11-12):1299-305. doi: 10.1289/ehp.1205350. [PMID: 23912598]
  • F Vela-Soria, O Ballesteros, I Rodríguez, A Zafra-Gómez, L Ballesteros, R Cela, A Navalón. A new treatment by dispersive liquid-liquid microextraction for the determination of parabens in human serum samples. Analytical and bioanalytical chemistry. 2013 Sep; 405(23):7259-67. doi: 10.1007/s00216-013-7181-x. [PMID: 23857141]
  • Felice Cerreto, Patrizia Paolicelli, Stefania Cesa, Hend M Abu Amara, Felicia Diodata D'Auria, Giovanna Simonetti, Maria Antonietta Casadei. Solid lipid nanoparticles as effective reservoir systems for long-term preservation of multidose formulations. AAPS PharmSciTech. 2013 Jun; 14(2):847-53. doi: 10.1208/s12249-013-9972-y. [PMID: 23625652]
  • James M Mathews, Sherri S Brown, Purvi R Patel, Sherry R Black, Troy T Banks, Amy S Etheridge, Timothy R Fennell, Rodney W Snyder, Chad R Blystone, Suramya Waidyanatha. Metabolism and disposition of [14C]n-butyl-p-hydroxybenzoate in male and female Harlan Sprague Dawley rats following oral administration and dermal application. Xenobiotica; the fate of foreign compounds in biological systems. 2013 Feb; 43(2):169-81. doi: 10.3109/00498254.2012.702935. [PMID: 22830980]
  • Anna Pereira-Fernandes, Heidi Demaegdt, Karine Vandermeiren, Tine L M Hectors, Philippe G Jorens, Ronny Blust, Caroline Vanparys. Evaluation of a screening system for obesogenic compounds: screening of endocrine disrupting compounds and evaluation of the PPAR dependency of the effect. PloS one. 2013; 8(10):e77481. doi: 10.1371/journal.pone.0077481. [PMID: 24155963]
  • Pan Hu, Xin Chen, Rick J Whitener, Eric T Boder, Jeremy O Jones, Aleksey Porollo, Jiangang Chen, Ling Zhao. Effects of parabens on adipocyte differentiation. Toxicological sciences : an official journal of the Society of Toxicology. 2013 Jan; 131(1):56-70. doi: 10.1093/toxsci/kfs262. [PMID: 22956630]
  • Kristen W Smith, Joe M Braun, Paige L Williams, Shelley Ehrlich, Katharine F Correia, Antonia M Calafat, Xiaoyun Ye, Jennifer Ford, Myra Keller, John D Meeker, Russ Hauser. Predictors and variability of urinary paraben concentrations in men and women, including before and during pregnancy. Environmental health perspectives. 2012 Nov; 120(11):1538-43. doi: 10.1289/ehp.1104614. [PMID: 22721761]
  • Camilla Taxvig, Karin Dreisig, Julie Boberg, Christine Nellemann, Ane Blicher Schelde, Dorthe Pedersen, Michael Boergesen, Susanne Mandrup, Anne Marie Vinggaard. Differential effects of environmental chemicals and food contaminants on adipogenesis, biomarker release and PPARγ activation. Molecular and cellular endocrinology. 2012 Sep; 361(1-2):106-15. doi: 10.1016/j.mce.2012.03.021. [PMID: 22526026]
  • Tilak Khanal, Hyung Gyun Kim, Sun Woo Jin, Eol Shim, Hwa Jeong Han, Keumhan Noh, Sunkyoung Park, Dae Hun Lee, Wonku Kang, Hee Kyung Yeo, Dong Hyun Kim, Tae Cheon Jeong, Hye Gwang Jeong. Protective role of metabolism by intestinal microflora in butyl paraben-induced toxicity in HepG2 cell cultures. Toxicology letters. 2012 Sep; 213(2):174-83. doi: 10.1016/j.toxlet.2012.07.004. [PMID: 22814205]
  • Komal Shah, Ramtej J Verma. Protection against butyl p-hydroxybenzoic acid induced oxidative stress by Ocimum sanctum extract in mice liver. Acta poloniae pharmaceutica. 2012 Sep; 69(5):865-70. doi: ". [PMID: 23061282]
  • Nicolas Aubert, Thibault Ameller, Jean-Jacques Legrand. Systemic exposure to parabens: pharmacokinetics, tissue distribution, excretion balance and plasma metabolites of [14C]-methyl-, propyl- and butylparaben in rats after oral, topical or subcutaneous administration. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2012 Mar; 50(3-4):445-54. doi: 10.1016/j.fct.2011.12.045. [PMID: 22265941]
  • Claire Philippat, Marion Mortamais, Cécile Chevrier, Claire Petit, Antonia M Calafat, Xiaoyun Ye, Manori J Silva, Christian Brambilla, Isabelle Pin, Marie-Aline Charles, Sylvaine Cordier, Rémy Slama. Exposure to phthalates and phenols during pregnancy and offspring size at birth. Environmental health perspectives. 2012 Mar; 120(3):464-70. doi: 10.1289/ehp.1103634. [PMID: 21900077]
  • Mari Egawa, Kentaro Aoki, Yongkun Sun, Toshiyuki Hosokawa, Takeshi Saito, Masaaki Kurasaki. Effects of parabens on apoptosis induced by serum-free medium. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2012; 47(3):196-204. doi: 10.1080/03601234.2012.634341. [PMID: 22375591]
  • Komal H Shah, Ramtej J Verma. Butyl p-hydroxybenzoic acid induces oxidative stress in mice liver--an in vivo study. Acta poloniae pharmaceutica. 2011 Nov; 68(6):875-9. doi: ". [PMID: 22125952]
  • Yasuto Kido, Pär Matsson, Kathleen M Giacomini. Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2. Journal of medicinal chemistry. 2011 Jul; 54(13):4548-58. doi: 10.1021/jm2001629. [PMID: 21599003]
  • John D Meeker, Tiffany Yang, Xiaoyun Ye, Antonia M Calafat, Russ Hauser. Urinary concentrations of parabens and serum hormone levels, semen quality parameters, and sperm DNA damage. Environmental health perspectives. 2011 Feb; 119(2):252-7. doi: 10.1289/ehp.1002238. [PMID: 20876036]
  • Soo-Churl Cho, Soo-Young Bhang, Yun-Chul Hong, Min-Sup Shin, Boong-Nyun Kim, Jae-Won Kim, Hee-Jung Yoo, In Hee Cho, Hyo-Won Kim. Relationship between environmental phthalate exposure and the intelligence of school-age children. Environmental health perspectives. 2010 Jul; 118(7):1027-32. doi: 10.1289/ehp.0901376. [PMID: 20194078]
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  • Lizbeth López-Carrillo, Raúl U Hernández-Ramírez, Antonia M Calafat, Luisa Torres-Sánchez, Marcia Galván-Portillo, Larry L Needham, Rubén Ruiz-Ramos, Mariano E Cebrián. Exposure to phthalates and breast cancer risk in northern Mexico. Environmental health perspectives. 2010 Apr; 118(4):539-44. doi: 10.1289/ehp.0901091. [PMID: 20368132]
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  • Suzanne Abbas, Hélène Greige-Gerges, Nancy Karam, Marie-Hélène Piet, Patrick Netter, Jacques Magdalou. Metabolism of parabens (4-hydroxybenzoic acid esters) by hepatic esterases and UDP-glucuronosyltransferases in man. Drug metabolism and pharmacokinetics. 2010; 25(6):568-77. doi: 10.2133/dmpk.dmpk-10-rg-013. [PMID: 20930423]
  • Hanne Frederiksen, Camilla Taxvig, Ulla Hass, Anne M Vinggaard, Christine Nellemann. Higher levels of ethyl paraben and butyl paraben in rat amniotic fluid than in maternal plasma after subcutaneous administration. Toxicological sciences : an official journal of the Society of Toxicology. 2008 Dec; 106(2):376-83. doi: 10.1093/toxsci/kfn171. [PMID: 18713765]
  • Kishore Kamaraju, Sergei Sukharev. The membrane lateral pressure-perturbing capacity of parabens and their effects on the mechanosensitive channel directly correlate with hydrophobicity. Biochemistry. 2008 Oct; 47(40):10540-50. doi: 10.1021/bi801092g. [PMID: 18795793]
  • Julie Boberg, Stine Metzdorff, Rasmus Wortziger, Marta Axelstad, Leon Brokken, Anne Marie Vinggaard, Majken Dalgaard, Christine Nellemann. Impact of diisobutyl phthalate and other PPAR agonists on steroidogenesis and plasma insulin and leptin levels in fetal rats. Toxicology. 2008 Sep; 250(2-3):75-81. doi: 10.1016/j.tox.2008.05.020. [PMID: 18602967]
  • Aiming Qi, Meigui Li, Liqiu Mao. [Application of single drop microextraction in the determination of phthalate esters and parabens in drugs by gas chromatography-mass spectrometry]. Se pu = Chinese journal of chromatography. 2008 May; 26(3):306-9. doi: . [PMID: 18724664]
  • Nadeem Rezaq Janjua, Hanne Frederiksen, Niels E Skakkebaek, Hans Christian Wulf, Anna-Maria Andersson. Urinary excretion of phthalates and paraben after repeated whole-body topical application in humans. International journal of andrology. 2008 Apr; 31(2):118-30. doi: 10.1111/j.1365-2605.2007.00841.x. [PMID: 18194284]
  • Bharti Sapra, Subheet Jain, A K Tiwary. Percutaneous permeation enhancement by terpenes: mechanistic view. The AAPS journal. 2008; 10(1):120-32. doi: 10.1208/s12248-008-9012-0. [PMID: 18446512]
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